Soft tissue sarcoma

Common Name(s)

Soft tissue sarcoma

Soft-tissue sarcomas are cancerous tumors that begin in the soft tissues of the body. This stype of sarcoma is rare in adults and not very common in children. Symptoms of soft-tissue sarcomas are not noticeable initially, but as the tumor grows, several of the following may develop: a lump or swelling, a blockage in the stomach or intestines if the tumor is located in the abdomen or digestive tract, and pain, particularly if the tumor sits on or near a bundle of nerves. Soft-tissue sarcomas can go by a variety of names, depending on the location of origination, and include disorders such as Kaposi’s sasrcoma, synovial sarcoma, liposarcoma, fibrosaroma, and neurofibrosarcoma.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Soft tissue sarcoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Soft tissue sarcoma" returned 390 free, full-text research articles on human participants. First 3 results:

Comorbidity is independently associated with poor outcome in extremity soft tissue sarcoma.
 

Author(s): Seungcheol Kang, Han-Soo Kim, Wanlim Kim, Jun Ho Kim, So Hyun Kang, Ilkyu Han

Journal: Clin Orthop Surg. 2015 Mar;7(1):120-30.

 

Comorbidity has not been examined as an independent prognostic factor in soft tissue sarcoma (STS). We examined the prognostic impact of comorbidity on oncologic outcome in STS with an adjustment for possible confounding factors.

Last Updated: 2 Mar 2015

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Chemotherapy in soft-tissue sarcoma: where do we go from here?
 

Author(s): William Gwin, Richard F Riedel

Journal: Oncology (Williston Park, N.Y.). 2015 Jan;29(1):50, 52-3.

 

Last Updated: 16 Jan 2015

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Role of matrix metalloproteinase (MMP) 2 and MMP-9 in soft tissue sarcoma.
 

Author(s): Hyun Kee Yang, Kwang Cheul Jeong, Yang Kyung Kim, Sung Taek Jung

Journal: Clin Orthop Surg. 2014 Dec;6(4):443-54.

 

We investigated the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in malignant fibrous histiocytoma (MFH), and determined whether these could be useful as prognostic factors.

Last Updated: 1 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Soft tissue sarcoma" returned 33 free, full-text review articles on human participants. First 3 results:

Absence of 19 known hotspot oncogenic mutations in soft tissue clear cell sarcoma: two cases report with review of the literature.
 

Author(s): Chunxia Liu, Yan Ren, Xiaoying Li, Yuwen Cao, Yunzhao Chen, Xiaobin Cui, Li Li, Feng Li

Journal:

 

Clear cell sarcoma (CCS) of the tendons and aponeuroses is a rare soft tissue sarcoma that morphologically resembles cutaneous malignant melanoma but exhibits a distinct molecular profile. Gastrointestinal (GI) CCS is extremely rare. In this study, two cases of CCS were presented: ...

Last Updated: 8 Sep 2014

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Soft tissue sarcoma: an update on systemic treatment options for patients with advanced disease.
 

Author(s): Patrick Schöffski, Jasmien Cornillie, Agnieszka Wozniak, Haifu Li, Daphne Hompes

Journal: Oncol Res Treat. 2014 ;37(6):355-62.

 

Sarcomas are a group of rare solid tumours arising from mesenchymal or connective tissue. This review focuses on soft tissue sarcoma and covers general topics such as the epidemiology, age distribution, site of disease, histogenesis, histological subtypes, prognosis and outcome of ...

Last Updated: 6 Jun 2014

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Sarcoma classification: an update based on the 2013 World Health Organization Classification of Tumors of Soft Tissue and Bone.
 

Author(s): Leona A Doyle

Journal: Cancer. 2014 Jun;120(12):1763-74.

 

The 2013 World Health Organization Classification of Tumors of Soft Tissue and Bone incorporates changes in tumor classification, as well as new genetic insights into the pathogenesis of many different tumor types that have emerged over the 11 years since the publication of the prior ...

Last Updated: 4 Jun 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery
 

Status: Recruiting

Condition Summary: Adult Fibrosarcoma; Alveolar Soft Part Sarcoma; Angiomatoid Fibrous Histiocytoma; Atypical Fibroxanthoma; Clear Cell Sarcoma of Soft Tissue; Epithelioid Malignant Peripheral Nerve Sheath Tumor; Epithelioid Sarcoma; Extraskeletal Myxoid Chondrosarcoma; Extraskeletal Osteosarcoma; Fibrohistiocytic Neoplasm; Glomus Tumor of the Skin; Inflammatory Myofibroblastic Tumor; Intimal Sarcoma; Leiomyosarcoma; Liposarcoma; Low Grade Fibromyxoid Sarcoma; Low Grade Myofibroblastic Sarcoma; Malignant Cutaneous Granular Cell Tumor; Malignant Peripheral Nerve Sheath Tumor; Malignant Triton Tumor; Mesenchymal Chondrosarcoma; Myxofibrosarcoma; Myxoid Chondrosarcoma; Myxoinflammatory Fibroblastic Sarcoma; Nerve Sheath Neoplasm; PEComa; Pericytic Neoplasm; Plexiform Fibrohistiocytic Tumor; Sclerosing Epithelioid Fibrosarcoma; Stage IB Soft Tissue Sarcoma; Stage IIB Soft Tissue Sarcoma; Stage III Soft Tissue Sarcoma; Stage IV Soft Tissue Sarcoma; Synovial Sarcoma; Undifferentiated (Embryonal) Sarcoma; Undifferentiated High Grade Pleomorphic Sarcoma of Bone

 

Last Updated: 30 Jul 2015

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Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas
 

Status: Recruiting

Condition Summary: Childhood Alveolar Soft-part Sarcoma; Childhood Angiosarcoma; Childhood Desmoplastic Small Round Cell Tumor; Childhood Epithelioid Sarcoma; Childhood Fibrosarcoma; Childhood Leiomyosarcoma; Childhood Liposarcoma; Childhood Malignant Mesenchymoma; Childhood Neurofibrosarcoma; Childhood Synovial Sarcoma; Chordoma; Desmoid Tumor; Metastatic Childhood Soft Tissue Sarcoma; Nonmetastatic Childhood Soft Tissue Sarcoma; Recurrent Childhood Soft Tissue Sarcoma

 

Last Updated: 6 May 2015

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Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma
 

Status: Recruiting

Condition Summary: Adult Alveolar Soft Part Sarcoma; Adult Angiosarcoma; Adult Desmoplastic Small Round Cell Tumor; Adult Epithelioid Hemangioendothelioma; Adult Epithelioid Sarcoma; Adult Extraskeletal Myxoid Chondrosarcoma; Adult Extraskeletal Osteosarcoma; Adult Fibrosarcoma; Adult Leiomyosarcoma; Adult Liposarcoma; Adult Malignant Mesenchymoma; Adult Malignant Peripheral Nerve Sheath Tumor; Adult Rhabdomyosarcoma; Adult Synovial Sarcoma; Adult Undifferentiated Pleomorphic Sarcoma; Malignant Adult Hemangiopericytoma; Recurrent Adult Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma

 

Last Updated: 24 Jun 2015

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