Soft tissue sarcoma

Common Name(s)

Soft tissue sarcoma

Soft-tissue sarcomas are cancerous tumors that begin in the soft tissues of the body. This stype of sarcoma is rare in adults and not very common in children. Symptoms of soft-tissue sarcomas are not noticeable initially, but as the tumor grows, several of the following may develop: a lump or swelling, a blockage in the stomach or intestines if the tumor is located in the abdomen or digestive tract, and pain, particularly if the tumor sits on or near a bundle of nerves. Soft-tissue sarcomas can go by a variety of names, depending on the location of origination, and include disorders such as Kaposi’s sasrcoma, synovial sarcoma, liposarcoma, fibrosaroma, and neurofibrosarcoma.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Soft tissue sarcoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Soft tissue sarcoma" returned 382 free, full-text research articles on human participants. First 3 results:

Chemotherapy in soft-tissue sarcoma: where do we go from here?
 

Author(s): William Gwin, Richard F Riedel

Journal: Oncology (Williston Park, N.Y.). 2015 Jan;29(1):50, 52-3.

 

Last Updated: 16 Jan 2015

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Comparative study of planned and unplanned excisions for the treatment of soft tissue sarcoma of the extremities.
 

Author(s): Carlos E H Hanasilo, Marcelo S Casadei, Leandro Auletta, Eliane M I Amstalden, Silvia R F Matte, Mauricio Etchebehere

Journal: Clinics (Sao Paulo). 2014 Sep;69(9):579-84.

 

Unplanned excision of soft tissue sarcomas is common because benign soft tissue lesions are very frequent. This study evaluated the impact of unplanned resections on overall survival, local recurrence and distant metastasis in patients with soft tissue sarcomas of the extremities.

Last Updated: 16 Oct 2014

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Relative mortality in soft tissue sarcoma patients: a Danish population-based cohort study.
 

Author(s): Katja Maretty-Nielsen, Ninna Aggerholm-Pedersen, Johnny Keller, Akmal Safwat, Steen Baerentzen, Alma B Pedersen

Journal:

 

Cancer-specific survival estimates rely on precise and correct data on the cause of death; however, these data can be difficult to acquire, particularly in elderly patients where comorbidity is common. Furthermore, while some deaths are directly related to cancer, others are more ...

Last Updated: 24 Sep 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Soft tissue sarcoma" returned 31 free, full-text review articles on human participants. First 3 results:

Soft tissue sarcoma: an update on systemic treatment options for patients with advanced disease.
 

Author(s): Patrick Schöffski, Jasmien Cornillie, Agnieszka Wozniak, Haifu Li, Daphne Hompes

Journal: Oncol Res Treat. 2014 ;37(6):355-62.

 

Sarcomas are a group of rare solid tumours arising from mesenchymal or connective tissue. This review focuses on soft tissue sarcoma and covers general topics such as the epidemiology, age distribution, site of disease, histogenesis, histological subtypes, prognosis and outcome of ...

Last Updated: 6 Jun 2014

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Multidisciplinary management of soft tissue sarcoma.
 

Author(s): Lukas M Nystrom, Nickolas B Reimer, John D Reith, Long Dang, Robert A Zlotecki, Mark T Scarborough, C Parker Gibbs

Journal:

 

Soft tissue sarcoma is a rare malignancy, with approximately 11,000 cases per year encountered in the United States. It is primarily encountered in adults but can affect patients of any age. There are many histologic subtypes and the malignancy can be low or high grade. Appropriate ...

Last Updated: 28 Aug 2013

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Efficacy and safety of pharmacological interventions in second- or later-line treatment of patients with advanced soft tissue sarcoma: a systematic review.
 

Author(s): Sheetal Sharma, Shweta Takyar, Stephanie C Manson, Sarah Powell, Nicolas Penel

Journal:

 

Current guidelines recommend anthracycline-based chemotherapy primarily with doxorubicin either as monotherapy or in combination with ifosfamide as the first-line treatment for most advanced STS subtypes. Therapeutic options after failure of doxorubicin and/or ifosfamide are limited. ...

Last Updated: 26 Aug 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery
 

Status: Recruiting

Condition Summary: Adult Fibrosarcoma; Alveolar Soft Part Sarcoma; Angiomatoid Fibrous Histiocytoma; Atypical Fibroxanthoma; Clear Cell Sarcoma of Soft Tissue; Epithelioid Malignant Peripheral Nerve Sheath Tumor; Epithelioid Sarcoma; Extraskeletal Myxoid Chondrosarcoma; Extraskeletal Osteosarcoma; Fibrohistiocytic Neoplasm; Glomus Tumor of the Skin; Inflammatory Myofibroblastic Tumor; Intimal Sarcoma; Leiomyosarcoma; Liposarcoma; Low Grade Fibromyxoid Sarcoma; Low Grade Myofibroblastic Sarcoma; Malignant Cutaneous Granular Cell Tumor; Malignant Peripheral Nerve Sheath Tumor; Malignant Triton Tumor; Mesenchymal Chondrosarcoma; Myxofibrosarcoma; Myxoid Chondrosarcoma; Myxoinflammatory Fibroblastic Sarcoma; Neoplasm With Perivascular Epithelioid Cell Differentiation; Nerve Sheath Neoplasm; Pericytic Neoplasm; Plexiform Fibrohistiocytic Tumor; Sclerosing Epithelioid Fibrosarcoma; Stage IB Soft Tissue Sarcoma; Stage IIB Soft Tissue Sarcoma; Stage III Soft Tissue Sarcoma; Stage IV Soft Tissue Sarcoma; Synovial Sarcoma; Unclassified Pleomorphic Sarcoma of Bone; Undifferentiated (Embryonal) Sarcoma

 

Last Updated: 21 May 2015

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Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma
 

Status: Recruiting

Condition Summary: Adult Alveolar Soft-part Sarcoma; Adult Angiosarcoma; Adult Desmoplastic Small Round Cell Tumor; Adult Epithelioid Hemangioendothelioma; Adult Epithelioid Sarcoma; Adult Extraskeletal Chondrosarcoma; Adult Extraskeletal Osteosarcoma; Adult Fibrosarcoma; Adult Leiomyosarcoma; Adult Liposarcoma; Adult Malignant Fibrous Histiocytoma; Adult Malignant Hemangiopericytoma; Adult Malignant Mesenchymoma; Adult Neurofibrosarcoma; Adult Rhabdomyosarcoma; Adult Synovial Sarcoma; Childhood Alveolar Soft-part Sarcoma; Childhood Angiosarcoma; Childhood Desmoplastic Small Round Cell Tumor; Childhood Epithelioid Hemangioendothelioma; Childhood Epithelioid Sarcoma; Childhood Fibrosarcoma; Childhood Leiomyosarcoma; Childhood Liposarcoma; Childhood Malignant Hemangiopericytoma; Childhood Malignant Mesenchymoma; Childhood Neurofibrosarcoma; Childhood Synovial Sarcoma; Dermatofibrosarcoma Protuberans; Metastatic Childhood Soft Tissue Sarcoma; Nonmetastatic Childhood Soft Tissue Sarcoma; Recurrent Adult Soft Tissue Sarcoma; Recurrent Childhood Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma

 

Last Updated: 5 Jan 2015

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Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas
 

Status: Recruiting

Condition Summary: Childhood Alveolar Soft-part Sarcoma; Childhood Angiosarcoma; Childhood Desmoplastic Small Round Cell Tumor; Childhood Epithelioid Sarcoma; Childhood Fibrosarcoma; Childhood Leiomyosarcoma; Childhood Liposarcoma; Childhood Malignant Mesenchymoma; Childhood Neurofibrosarcoma; Childhood Synovial Sarcoma; Chordoma; Desmoid Tumor; Metastatic Childhood Soft Tissue Sarcoma; Nonmetastatic Childhood Soft Tissue Sarcoma; Recurrent Childhood Soft Tissue Sarcoma

 

Last Updated: 6 May 2015

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