Sleep Apnea

Common Name(s)

Sleep Apnea

Sleep apnea is an ongoing disorder characterized by pauses in breathing that occur while sleeping. These disruptions can occur 30 times or more per hour. After the pauses, breathing will resume, sometimes accompanied by choking or snorting. Some symptoms include: daytime sleepiness (hypersomnia), loud snoring, headaches, sore throat, or dry mouth in the morning, insomnia, or abrupt awakenings in the night. There are two types of sleep apnea: obstructive and central. Obstructive sleep apnea is more common and is triggered by the airway collapsing or becoming blocked during sleep. Obstructive sleep apnea is most common in overweight people. Central sleep apnea occurs when the area of the brain that controls breathing fails to send signals to the breathing muscles. Central sleep apnea can affect anyone and can occur in addition to obstructive sleep apnea.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sleep Apnea" for support, advocacy or research.

American Sleep Apnea Association

Our mission is to reduce injury, disability and death from sleep apnea and to enhance the lives of those affected by this common disorder.

Last Updated: 9 Jan 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sleep Apnea" for support, advocacy or research.

American Sleep Apnea Association

Our mission is to reduce injury, disability and death from sleep apnea and to enhance the lives of those affected by this common disorder.

http://www.sleepapnea.org

Last Updated: 9 Jan 2013

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General Support Organizations

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General Resources

Online Directory of Products and Services

A directory of products and services for the apnea patient.

Updated 9 Jan 2013

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Apnea Support Forum

Internet Message Board for patients to interact with other patients.

Updated 9 Jan 2013

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CPAP Assistance Program

A program to provide gently used PAP devices to those who have no insurance or their insurance does not cover equipment.

Updated 9 Jan 2013

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Blogs

Executive Director Blog

The ASAA Executive Director keeps a sometime journal of his activities.

Updated 9 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Sleep Apnea" returned 1730 free, full-text research articles on human participants. First 3 results:

[Association of glucose transporter 4 gene polymorphism with hypoxia caused by obstructive sleep apnea syndrome and with related inflammatory factors].
 

Author(s): Ting Yin, Nan-fang Li, Li-gen Ai, Xiao-guang Yao, Jing Hong, Ling Zhou, Jian-qiong Kong

Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2014 Aug;36(4):400-9.

 

To investigate the relationship between genetic polymorphisms of glucose transporter 4 (GLUT4) and hypoxia caused by obstructive sleep apnea syndrome (OSAS) as well as with related inflammatory factors.

Last Updated: 1 Sep 2014

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Obstructive sleep apnea and the prevalence and incidence of cancer.
 

Author(s): Tetyana Kendzerska, Richard S Leung, Gillian Hawker, George Tomlinson, Andrea S Gershon

Journal: CMAJ. 2014 Sep;186(13):985-92.

 

A link between obstructive sleep apnea and cancer development or progression has been suggested, possibly through chronic hypoxemia, but supporting evidence is limited. We examined the association between the severity of obstructive sleep apnea and prevalent and incident cancer, controlling ...

Last Updated: 16 Sep 2014

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Examining the mechanism of action of a new device using oral pressure therapy for the treatment of obstructive sleep apnea.
 

Author(s): Richard J Schwab, C Kim, Lawrence Siegel, B T Keenan, Jed Black, Mehran Farid-Moayer, Jonathan Podmore, Matt Vaska

Journal:

 

The objective of this study was to explore the mechanism of action of the oral pressure therapy (OPT) device, a new treatment for sleep apnea.

Last Updated: 25 Jul 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Sleep Apnea" returned 245 free, full-text review articles on human participants. First 3 results:

[The treatment of central sleep-apnea syndrome, updated information, and review of the literature].
 

Author(s): Handan Inönü Köseoğlu, Asiye Kanbay, Oğuz Köktürk

Journal: Tuberk Toraks. 2014 ;62(1):68-78.

 

Central sleep-apnea syndrome (CSAS) is a disease state characterized by respiratory arrest as a result of decrease or lack of respiratory drive originating from respiratory center. Although it is seen in less than 5% of the casses who consult to the sleep disorders center, incidence ...

Last Updated: 12 May 2014

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Effect of continuous positive airway pressure on lipid profile in patients with obstructive sleep apnea syndrome: a meta-analysis of randomized controlled trials.
 

Author(s): Huajun Xu, Hongliang Yi, Jian Guan, Shankai Yin

Journal: Atherosclerosis. 2014 Jun;234(2):446-53.

 

Obstructive sleep apnea syndrome (OSAS) is an independent risk factor for development of dyslipidemia. Continuous positive airway pressure (CPAP) is the first-line treatment for OSAS. However, it is unclear whether CPAP improves lipid metabolism.

Last Updated: 23 May 2014

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The association of 5-HT2A, 5-HTT, and LEPR polymorphisms with obstructive sleep apnea syndrome: a systematic review and meta-analysis.
 

Author(s): Baodong Qin, Zhen Sun, Yan Liang, Zaixing Yang, Renqian Zhong

Journal:

 

A consensus has not been reached regarding the association of several different gene polymorphisms and susceptibility to obstructive sleep apnea syndrome (OSAS). We performed a meta-analysis to better evaluate the associations between 5-HT2A, 5-HTT, and LEPR polymorphisms, and OSAS.

Last Updated: 23 Apr 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Testing the Elevation as Sleep Apnea Treatment
 

Status: Not yet recruiting

Condition Summary: Sleep Apnea, Obstructive; Sleep Apnea Syndromes; Sleep

 

Last Updated: 14 Sep 2014

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Effect of Obstructive Sleep Apnea Syndrome on Insulin Sensitivity and Cardiovascular Risk in PCOS Adolescents
 

Status: Recruiting

Condition Summary: Obstructive Sleep Apnea Syndrome; Polycystic Ovary Syndrome; Sleep Apnea

 

Last Updated: 10 Sep 2014

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Undetected Sleep Apnea in the Postanesthesia Acute Care Unit (PACU)
 

Status: Recruiting

Condition Summary: Sleep Apnea, Obstructive

 

Last Updated: 28 Oct 2014

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