Situs inversus

Common Name(s)

Situs inversus

Situs inversus is a condition in which the internal organs of the abdomen (stomach) and thorax (chest) lie in mirror image of their normal body position. It can occur alone, without any other anomalies, or it can be  a part of a syndrome with various other defects. Situs inversus has been inherited in different ways in different families. Autosomal dominant, autosomal recessive, and X-linked inheritance have been reported. Treatment, when needed, is symptomatic and supportive.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Situs inversus" for support, advocacy or research.

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Heterotaxy Foundation

The Heterotaxy Foundation is a non-profit organization created to raise funds for research and promote awareness of a rare disease called Heterotaxy Syndrome.

Last Updated: 12 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Situs inversus" for support, advocacy or research.

Logo
Heterotaxy Foundation

The Heterotaxy Foundation is a non-profit organization created to raise funds for research and promote awareness of a rare disease called Heterotaxy Syndrome.

http://www.heterotaxy.org

Last Updated: 12 Feb 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Situs inversus" returned 126 free, full-text research articles on human participants. First 3 results:

Aortic arch rerouting and OPCAB in a patient with situs inversus totalis.
 

Author(s): Yusuke Irisawa, Tadashi Kitamura, Tsuyoshi Taketani, Naoji Hanayama, Norihiko Oka, Takahiro Tomoyasu, Keiichi Itatani, Miyuki Shibata, Hidenori Hayashi, Takamichi Inoue, Kagami Miyaji

Journal: Int Heart J. 2014 ;55(3):278-9.

 

Endovascular therapy approaches for aortic aneurysm have lowered the mortality and morbidity rates even in high-risk patients; moreover, these approaches are applied in the management of aortic arch pathologies by transposition of the supra-aortic branches. We present the case of ...

Last Updated: 26 May 2014

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Orthotopic liver transplantation in situs inversus adult from an ABO-incompatible donor with situs inversus.
 

Author(s): Songfeng Yu, Hua Guo, Wu Zhang, Jun Yu, Sheng Yan, Jian Wu, Min Zhang, Shusen Zheng

Journal:

 

Situs inversus is a rare congenital anomaly characterized by the complete inversion of thoracic and abdominal organs. Liver transplantation in such patients or from donors in situs inversus is technically challenging because of the reversed anatomic structures. A small number of successful ...

Last Updated: 17 Mar 2014

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Pancreaticoduodenectomy for biliary tract carcinoma with situs inversus totalis: difficulties and technical notes based on two cases.
 

Author(s): Daisuke Kyuno, Yasutoshi Kimura, Masafumi Imamura, Motonobu Uchiyama, Masayuki Ishii, Makoto Meguro, Masaki Kawamoto, Toru Mizuguchi, Koichi Hirata

Journal:

 

Situs inversus totalis (SIT) denotes complete right-left inversion of the thoracic and abdominal viscera. Diagnosis and surgical procedures for abdominal pathology in patients with SIT are technically more complicated because of mirror-image transposition of the visceral organs. Moreover, ...

Last Updated: 20 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Situs inversus" returned 8 free, full-text review articles on human participants. First 3 results:

Situs inversus in association with duodenal atresia.
 

Author(s): Ademola Olusegun Talabi, Oludayo Adedapo Sowande, Adebayo Gbenga Tanimola, Olusanya Adejuyigbe

Journal: Afr J Paediatr Surg. ;10(3):275-8.

 

Situs inversus in association with duodenal atresia is very rare. A high index of suspicion coupled with appropriate evaluation is necessary for diagnosis and operative planning. We report a case of a 5-day-old who presented with duodenal atresia associated with polysplenia and situs ...

Last Updated: 6 Nov 2013

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Tetralogy of fallot with dextrocardia and situs inversus in a 7-year-old boy.
 

Author(s): Michael Dilorenzo, Samuel Weinstein, Rajesh Shenoy

Journal: Tex Heart Inst J. 2013 ;40(4):481-3.

 

Tetralogy of Fallot is one of the most frequently diagnosed congenital cardiac abnormalities; however, its association with dextrocardia and situs inversus is reported only rarely. We report a case of these findings in a 7-year-old boy, describe the patient's postoperative course, ...

Last Updated: 1 Oct 2013

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Endovascular repair of blunt aortic injury in a patient with situs inversus and dextrocardia.
 

Author(s): John F Bilello, Peter L Birnbaum, Chandra Venugopal, Leo L Fong

Journal: J. Vasc. Surg.. 2011 Sep;54(3):857-9.

 

A 24-year-old male pedestrian with situs inversus and dextrocardia was struck by a car and sustained multiple injuries, including a pseudoaneurysm of the proximal descending thoracic aorta. A thoracic endograft was deployed to exclude the blunt aortic injury. We are not aware of any ...

Last Updated: 5 Sep 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Ambrisentan in Single Ventricle
 

Status: Not yet recruiting

Condition Summary: Hypoplastic Left Heart Syndrome; Hypoplastic Right-sided Heart Complex

 

Last Updated: 7 Nov 2014

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Early Detection and Characterization of Primary Ciliary Dyskinesia
 

Status: Recruiting

Condition Summary: Primary Ciliary Dyskinesia

 

Last Updated: 7 May 2012

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Inflammatory and Microbiologic Markers in Sputum: Comparing Cystic Fibrosis With Primary Ciliary Dyskinesia
 

Status: Recruiting

Condition Summary: Cystic Fibrosis; Primary Ciliary Dyskinesia

 

Last Updated: 30 Aug 2013

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