Situs inversus

Common Name(s)

Situs inversus

Situs inversus is a condition in which the internal organs of the abdomen (stomach) and thorax (chest) lie in mirror image of their normal body position. It can occur alone, without any other anomalies, or it can be  a part of a syndrome with various other defects. Situs inversus has been inherited in different ways in different families. Autosomal dominant, autosomal recessive, and X-linked inheritance have been reported. Treatment, when needed, is symptomatic and supportive.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Situs inversus" for support, advocacy or research.

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Heterotaxy Foundation

The Heterotaxy Foundation is a non-profit organization created to raise funds for research and promote awareness of a rare disease called Heterotaxy Syndrome.

Last Updated: 12 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Situs inversus" for support, advocacy or research.

Logo
Heterotaxy Foundation

The Heterotaxy Foundation is a non-profit organization created to raise funds for research and promote awareness of a rare disease called Heterotaxy Syndrome.

http://www.heterotaxy.org

Last Updated: 12 Feb 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Situs inversus" returned 180 free, full-text research articles on human participants. First 3 results:

VACTER syndrome with situs inversus totalis: Case report and a new syndrome.
 

Author(s): Wei Wu, Zhibao Lv, Weijue Xu, Jiangbing Liu, Wei Jia

Journal: Medicine (Baltimore). 2017 Jun;96(25):e7260.

 

The association of situs inversus totalis (SIT) and VACTERL syndrome an extremely rare coincidence.

Last Updated: 22 Jun 2017

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Jejunojejunal intussusception after Roux-en-Y gastric bypass in a situs inversus totalis patient: A case report.
 

Author(s): Guangyi Jiang, Baojuan Fu, Sheng Lv, Junjie Hong, Xiujun Cai

Journal: Medicine (Baltimore). 2017 Apr;96(15):e6589.

 

Situs inversus totalis (SIT) is an uncommon clinical manifestation. Patients with SIT typically have malformation in the thorax and abdomen. The incidence of SIT ranges from 1/10,000 to 1/20,000 (Al-Jumaily and Hoche. J Laparoendosc Adv Surg Tech A 2001;11:229). Jejunojejunal intussusception ...

Last Updated: 13 Apr 2017

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Congenitally Corrected Transposition of the Great Arteries and Situs Inversus in an Octogenarian With Systemic Right Ventricular Failure.
 

Author(s): Mikio Shiba, Shigefumi Fukui, Hideo Ohuchi, Jin Ueda, Akihiro Tsuji, Yoshiaki Morita, Aya Miyazaki, Takeshi Ogo, Satoshi Yasuda, Isao Shiraishi, Norifumi Nakanishi

Journal: Int Heart J. 2017 Feb;58(1):151-154.

 

Systemic right ventricular (RV) failure in patients with congenitally corrected transposition of the great arteries (ccTGA), a major cause of mortality in the long-term follow-up, is usually induced by concomitant severe morphologically tricuspid regurgitation (TR) with/without Ebstein's ...

Last Updated: 7 Nov 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Situs inversus" returned 13 free, full-text review articles on human participants. First 3 results:

PEComa of the uterus with coexistence of situs inversus totalis, a case report and literature review.
 

Author(s): Yang Han, Ting-ting Liu, Xue-shan Qiu, Qing-chang Li, Yi Zhao, Xiao-Yan Pang, En-hua Wang

Journal:

 

PEComas are a group of very rare mesenchymal neoplasms, which express myogenic and melanocytic markers, such as HMB-45 and actin. Situs inversus totalis represents a complete left to right side transposition of the asymmetrical thoracic and abdominal organs and incorporates dextrocardia. ...

Last Updated: 13 Aug 2015

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Therapeutic endoscopic retrograde cholangiopancreatography in a patient with situs inversus viscerum.
 

Author(s): Yi Hu, Hao Zeng, Xiao-Lin Pan, Nong-Hua Lv, Zhi-Jian Liu, Yang Hu

Journal: World J. Gastroenterol.. 2015 May;21(18):5744-8.

 

Situs inversus viscerum (SIV) is a rare congenital condition characterized by complete transposition of all viscera. This anatomical pathology makes endoscopic retrograde cholangiopancreatography (ERCP) technically difficult. We report a new case of a 70-year-old Chinese male with ...

Last Updated: 19 May 2015

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Simplified technique of laparoscopic cholecystectomy in a patient with situs inversus: a case report and review of techniques.
 

Author(s): Natthawut Phothong, Thawatchai Akaraviputh, Vitoon Chinswangwatanakul, Atthaphorn Trakarnsanga

Journal:

 

Situs inversus is a rare and silent autosomal recessive disorder occurring in 1:5,000 to 1:20,000 individuals. Laparoscopic cholecystectomy, a standard treatment for gallbladder disease in the general population, is very challenging in patients with situs inversus, especially for ...

Last Updated: 17 Apr 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Fibrosis, Valvular and Ventricular Function in Patients With TGA
 

Status: Recruiting

Condition Summary: Transposition of Great Vessels

 

Last Updated: 11 May 2016

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Cardiovascular MRI and Cardiopulmonary Exercise Capacity After Neonatal ASO) in Young Adults
 

Status: Recruiting

Condition Summary: Transposition of the Great Arteries; Artery Switch Operation

 

Last Updated: 17 Feb 2016

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Transcatheter Valve Implantation in Patients With Dysfunctional Left and Right Sided Heart Valves
 

Status: Recruiting

Condition Summary: Eisenmenger Syndrome

 

Last Updated: 3 Jun 2016

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