Situs inversus

Common Name(s)

Situs inversus

Situs inversus is a condition in which the internal organs of the abdomen (stomach) and thorax (chest) lie in mirror image of their normal body position. It can occur alone, without any other anomalies, or it can be  a part of a syndrome with various other defects. Situs inversus has been inherited in different ways in different families. Autosomal dominant, autosomal recessive, and X-linked inheritance have been reported. Treatment, when needed, is symptomatic and supportive.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Situs inversus" for support, advocacy or research.

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Heterotaxy Foundation

The Heterotaxy Foundation is a non-profit organization created to raise funds for research and promote awareness of a rare disease called Heterotaxy Syndrome.

Last Updated: 12 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Situs inversus" for support, advocacy or research.

Logo
Heterotaxy Foundation

The Heterotaxy Foundation is a non-profit organization created to raise funds for research and promote awareness of a rare disease called Heterotaxy Syndrome.

http://www.heterotaxy.org

Last Updated: 12 Feb 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Situs inversus" returned 179 free, full-text research articles on human participants. First 3 results:

Nephrotic syndrome and situs inversus--A chance association?
 

Author(s): Vaishali B More, Amit Saxena, Ratna Sharma

Journal: Saudi J Kidney Dis Transpl. 2016 Jan;27(1):177-8.

 

Last Updated: 20 Jan 2016

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Aortic root remodeling and external aortic annuloplasty to treat sinus of Valsalva aneurysm in a patient with complete situs inversus.
 

Author(s): Charline Pujos, Marie-Catherine Morgant, Ghislain Malapert, Olivier Bouchot

Journal:

 

Sinus of Valsalva aneurysm is an uncommon anomaly of the aorta. It occurs most frequently in the right sinus of Valsalva. Complications depend on its size and location. Situs inversus totalis is a rare condition wherein organs are reversed from their normal positions (mirror image).

Last Updated: 8 Dec 2015

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A Patient with Advanced Gastric Cancer and Situs Inversus Totalis: Report of a Case.
 

Author(s): Taro Isobe, Suguru Ogata, Hideaki Kaku, Kousuke Hashimoto, Junya Kizaki, Satoru Matono, Hiroto Ishikawa, Naotaka Murakami, Tetsushi Kinugasa, Keishiro Aoyagi, Yoshito Akagi

Journal: Kurume Med J. 2015 ;61(3-4):73-6.

 

Situs inversus totalis (SIT) is a rare congenital anomaly in which the positions of the abdominal and thoracic cavity structures are reversed. The reported incidence of SIT is one in 10,000 to 50,000 live births. There are few reports of gastric cancer in individuals with SIT or of ...

Last Updated: 3 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Situs inversus" returned 14 free, full-text review articles on human participants. First 3 results:

PEComa of the uterus with coexistence of situs inversus totalis, a case report and literature review.
 

Author(s): Yang Han, Ting-ting Liu, Xue-shan Qiu, Qing-chang Li, Yi Zhao, Xiao-Yan Pang, En-hua Wang

Journal:

 

PEComas are a group of very rare mesenchymal neoplasms, which express myogenic and melanocytic markers, such as HMB-45 and actin. Situs inversus totalis represents a complete left to right side transposition of the asymmetrical thoracic and abdominal organs and incorporates dextrocardia. ...

Last Updated: 13 Aug 2015

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Therapeutic endoscopic retrograde cholangiopancreatography in a patient with situs inversus viscerum.
 

Author(s): Yi Hu, Hao Zeng, Xiao-Lin Pan, Nong-Hua Lv, Zhi-Jian Liu, Yang Hu

Journal: World J. Gastroenterol.. 2015 May;21(18):5744-8.

 

Situs inversus viscerum (SIV) is a rare congenital condition characterized by complete transposition of all viscera. This anatomical pathology makes endoscopic retrograde cholangiopancreatography (ERCP) technically difficult. We report a new case of a 70-year-old Chinese male with ...

Last Updated: 19 May 2015

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Simplified technique of laparoscopic cholecystectomy in a patient with situs inversus: a case report and review of techniques.
 

Author(s): Natthawut Phothong, Thawatchai Akaraviputh, Vitoon Chinswangwatanakul, Atthaphorn Trakarnsanga

Journal:

 

Situs inversus is a rare and silent autosomal recessive disorder occurring in 1:5,000 to 1:20,000 individuals. Laparoscopic cholecystectomy, a standard treatment for gallbladder disease in the general population, is very challenging in patients with situs inversus, especially for ...

Last Updated: 17 Apr 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Fibrosis, Valvular and Ventricular Function in Patients With TGA
 

Status: Recruiting

Condition Summary: Transposition of Great Vessels

 

Last Updated: 11 May 2016

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Cardiovascular MRI and Cardiopulmonary Exercise Capacity After Neonatal ASO) in Young Adults
 

Status: Recruiting

Condition Summary: Transposition of the Great Arteries; Artery Switch Operation

 

Last Updated: 17 Feb 2016

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Transcatheter Valve Implantation in Patients With Dysfunctional Left and Right Sided Heart Valves
 

Status: Recruiting

Condition Summary: Eisenmenger Syndrome

 

Last Updated: 3 Jun 2016

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