Silicosis

Common Name(s)

Silicosis

Silicosis is a respiratory disease caused by breathing in (inhaling) silica dust. There are three types of silicosis:

Simple chronic silicosis, the most common type of silicosis, results from long-term exposure (usually more than 20 years) to low amounts of silica dust. Simple chronic silicosis may cause people to have difficulty breathing.  Accelerated silicosis occurs after 5 to 15 years of exposure of higher levels of silica. Swelling of the lungs and other symptoms occur faster in this type of silicosis than in the simple chronic form.  Acute silicosis results from short-term exposure of large amounts of silica. The lungs become very inflamed and can fill with fluid, causing severe shortness of breath and low blood oxygen levels. Acute silicosis progresses rapidly and can be fatal within months. 

People who work in jobs where they are exposed to silica dust (mining, quarrying, construction, sand blasting, stone cutting) are at risk of developing this condition.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Silicosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Silicosis" returned 177 free, full-text research articles on human participants. First 3 results:

Osteoporosis: can it be related to silicosis?
 

Author(s): Mustafa Turgut Yildizgören, Timur Ekiz, Türkan Nadir Öziş, Ali Erdem Baki, Engin Tutkun, Neşe Özgirgin

Journal: Tuberk Toraks. 2014 ;62(1):98-9.

 

Last Updated: 12 May 2014

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Role of Fas/FasL pathway-mediated alveolar macrophages releasing inflammatory cytokines in human silicosis.
 

Author(s): San Qiao Yao, Qin Cheng He, Ju Xiang Yuan, Jie Chen, Gang Chen, Yao Lu, Yu Ping Bai, Chun Min Zhang, Yang Yuan, Ying Jun Xu

Journal: Biomed. Environ. Sci.. 2013 Nov;26(11):930-3.

 

Last Updated: 16 Dec 2013

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Cryptococcosis, silicosis, and tuberculous pseudotumor in the same pulmonary lobe.
 

Author(s): Geruza Alves da Silva, Daniel Ferracioli Brandão, Elcio Oliveira Vianna, João Batista Carlos de Sá Filho, José Baddini-Martinez

Journal: J Bras Pneumol. ;39(5):620-6.

 

Tuberculosis and cryptococcosis are infectious diseases that can result in the formation of single or multiple nodules in immunocompetent patients. Exposure to silica is known to raise the risk of infection with Mycobacterium tuberculosis. We report the case of an elderly man with ...

Last Updated: 6 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Silicosis" returned 15 free, full-text review articles on human participants. First 3 results:

A stone miner with both silicosis and constrictive pericarditis: case report and review of the literature.
 

Author(s): Yajian Jiang, Fangchun Shao

Journal:

 

The working environment of stone miners has been believed to cause their susceptibility to respiratory diseases. Silicosis is an occupational disease caused by exposure to crystalline silica dust which is marked by inflammation and scarring in the lung. The immune system boosted after ...

Last Updated: 16 Dec 2013

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Silica exposure, smoking, silicosis and lung cancer--complex interactions.
 

Author(s): Terry Brown

Journal: Occup Med (Lond). 2009 Mar;59(2):89-95.

 

Establishing a clear relationship between workplace exposures and cancer is often difficult. The latent period for cancer development can make it difficult to establish a definite cause-effect relationship. The picture is further complicated by variable job histories, concomitant ...

Last Updated: 23 Feb 2009

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Tuberculosis and silicosis: epidemiology, diagnosis and chemoprophylaxis.
 

Author(s): Carlos Eduardo Galvão Barboza, Daniel Hugo Winter, Márcia Seiscento, Ubiratan de Paula Santos, Mário Terra Filho

Journal: J Bras Pneumol. 2008 Nov;34(11):959-66.

 

Silicosis, the most prevalent of the pneumoconioses, is caused by inhalation of crystalline silica particles. Silica-exposed workers, with or without silicosis, are at increased risk for tuberculosis and nontuberculous mycobacteria-related diseases. The risk of a patient with silicosis ...

Last Updated: 22 Dec 2008

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety of Stem Cells Intrabronchial Instillation for Silicosis
 

Status: Recruiting

Condition Summary: Chronic and Accelerated Silicosis, Characterized With a Fibrotic Increase in the Last Two Years

 

Last Updated: 10 Nov 2010

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Last Updated: 16 Apr 2011

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DNA-damage Pathways in Workers Exposed to Silica (Caesar Stone)
 

Status: Not yet recruiting

Condition Summary: Silicosis

 

Last Updated: 1 Apr 2011

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