Silicosis

Common Name(s)

Silicosis

Silicosis is a respiratory disease caused by breathing in (inhaling) silica dust. There are three types of silicosis:

Simple chronic silicosis, the most common type of silicosis, results from long-term exposure (usually more than 20 years) to low amounts of silica dust. Simple chronic silicosis may cause people to have difficulty breathing.  Accelerated silicosis occurs after 5 to 15 years of exposure of higher levels of silica. Swelling of the lungs and other symptoms occur faster in this type of silicosis than in the simple chronic form.  Acute silicosis results from short-term exposure of large amounts of silica. The lungs become very inflamed and can fill with fluid, causing severe shortness of breath and low blood oxygen levels. Acute silicosis progresses rapidly and can be fatal within months. 

People who work in jobs where they are exposed to silica dust (mining, quarrying, construction, sand blasting, stone cutting) are at risk of developing this condition.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Silicosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Silicosis" returned 185 free, full-text research articles on human participants. First 3 results:

Notes from the Field: Update: Silicosis Mortality - United States, 1999-2013.
 

Author(s): Jacek M Mazurek, Patricia L Schleiff, John M Wood, Scott A Hendricks, Ainsley Weston,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2015 Jun;64(23):653-4.

 

Silicosis is a potentially fatal but preventable occupational lung disease caused by inhaling respirable crystalline silica (silica). Chronic silicosis, the most common form, occurs after exposure to relatively low silica concentrations for >10 years. Accelerated silicosis occurs ...

Last Updated: 19 Jun 2015

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Splenic calcification in a patient with silicosis.
 

Author(s): Kazuhiro Yatera, Shiro Ono, Keiji Joko, Hiroshi Mukae

Journal: Intern. Med.. 2015 ;54(8):987-8.

 

Last Updated: 16 Apr 2015

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Notes from the field: silicosis in a countertop fabricator - Texas, 2014.
 

Author(s): Gary K Friedman, Robert Harrison, Heidi Bojes, Karen Worthington, Margaret Filios,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2015 Feb;64(5):129-30.

 

In May 2014, the Texas Department of State Health Services was notified of a case of silicosis with progressive massive fibrosis in a Hispanic male aged 37 years who worked for an engineered stone countertop company as a polisher, laminator, and fabricator. He was exposed to dust ...

Last Updated: 14 Feb 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Silicosis" returned 16 free, full-text review articles on human participants. First 3 results:

Introduction: 'dying for gold': the effects of mineral miningon HIV, tuberculosis, silicosis, and occupational diseases in southern Africa.
 

Author(s): David Stuckler, Sarah Steele, Mark Lurie, Sanjay Basu

Journal: Int J Health Serv. 2013 ;43(4):639-49.

 

Mineral mining is among the world's most hazardous occupations. It is especially dangerous in southern Africa, where mining activity is a leading cause of HIV and tuberculosis epidemics. Inside mines, silica dust exposure causes long-term pulmonary damage. Living conditions are often ...

Last Updated: 8 Jan 2014

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A stone miner with both silicosis and constrictive pericarditis: case report and review of the literature.
 

Author(s): Yajian Jiang, Fangchun Shao

Journal:

 

The working environment of stone miners has been believed to cause their susceptibility to respiratory diseases. Silicosis is an occupational disease caused by exposure to crystalline silica dust which is marked by inflammation and scarring in the lung. The immune system boosted after ...

Last Updated: 16 Dec 2013

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Silica exposure, smoking, silicosis and lung cancer--complex interactions.
 

Author(s): Terry Brown

Journal: Occup Med (Lond). 2009 Mar;59(2):89-95.

 

Establishing a clear relationship between workplace exposures and cancer is often difficult. The latent period for cancer development can make it difficult to establish a definite cause-effect relationship. The picture is further complicated by variable job histories, concomitant ...

Last Updated: 23 Feb 2009

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 16 Apr 2011

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DNA-damage Pathways in Workers Exposed to Silica (Caesar Stone)
 

Status: Not yet recruiting

Condition Summary: Silicosis

 

Last Updated: 1 Apr 2011

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Efficacy of Weekly Rifapentine and Isoniazid for Tuberculosis Prevention
 

Status: Recruiting

Condition Summary: Silicosis; Tuberculosis

 

Last Updated: 25 Apr 2015

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