Sideroblastic Anemia

Common Name(s)

Sideroblastic Anemia

Sideroblastic anemia is a heterogeneous group of blood disorders characterized by an impaired ability of the bone marrow to produce normal red blood cells. The iron inside red blood cells is inadequately used to make hemoglobin, despite adequate or increased amounts of iron. Abnormal red blood cells called sideroblasts are found in the blood of people with these anemias. Sideroblastic anemias are classified as hereditary, acquired, and reversible.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sideroblastic Anemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Sideroblastic Anemia" returned 65 free, full-text research articles on human participants. First 3 results:

A novel hemizygous I418S mutation in the ALAS2 gene in a young Korean man with X-linked sideroblastic anemia.
 

Author(s): Soo Young Moon, In-Jae Jun, Ji-Eun Kim, Seung Jun Lee, Hyun Kyung Kim, Sung-Soo Yoon

Journal: Ann Lab Med. 2014 Mar;34(2):159-62.

 

Last Updated: 13 Mar 2014

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Mutation spectrum in Chinese patients affected by congenital sideroblastic anemia and a search for a genotype-phenotype relationship.
 

Author(s): Gang Liu, Shanshan Guo, Huiyuan Kang, Fuming Zhang, Yulin Hu, Lu Wang, Mianyang Li, Yongxin Ru, Clara Camaschella, Bing Han, Guangjun Nie

Journal: Haematologica. 2013 Dec;98(12):e158-60.

 

Last Updated: 10 Dec 2013

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X-linked sideroblastic anemia due to ALAS2 intron 1 enhancer element GATA-binding site mutations.
 

Author(s): Dean R Campagna, Charlotte I de Bie, Klaus Schmitz-Abe, Marion Sweeney, Anoop K Sendamarai, Paul J Schmidt, Matthew M Heeney, Helger G Yntema, Caroline Kannengiesser, Bernard Grandchamp, Charlotte M Niemeyer, Nine V A M Knoers, Sonia Swart, Gordon Marron, Richard van Wijk, Reinier A Raymakers, Alison May, Kyriacos Markianos, Sylvia S Bottomley, Dorine W Swinkels, Mark D Fleming

Journal: Am. J. Hematol.. 2014 Mar;89(3):315-9.

 

X-linked sideroblastic anemia (XLSA) is the most common form of congenital sideroblastic anemia. In affected males, it is uniformly associated with partial loss-of-function missense mutations in the erythroid-specific heme biosynthesis protein 5-aminolevulinate synthase 2 (ALAS2). ...

Last Updated: 28 Feb 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Sideroblastic Anemia" returned 1 free, full-text review articles on human participants. First 3 results:

[Congenital sideroblastic anemia-a new family with identification of K156E mutation of ALAS2 gene and literature review].
 

Author(s): Rui Cui, Zefeng Xu, Tiejun Qin, Yue Zhang, Zhijian Xiao

Journal: Zhonghua Xue Ye Xue Za Zhi. 2014 Feb;35(2):142-6.

 

To raise awareness of molecular pathogenesis and treatment of congenital sideroblastic anemia (CSA).

Last Updated: 10 Mar 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.