Sideroblastic Anemia

Common Name(s)

Sideroblastic Anemia

Sideroblastic anemia is a heterogeneous group of blood disorders characterized by an impaired ability of the bone marrow to produce normal red blood cells. The iron inside red blood cells is inadequately used to make hemoglobin, despite adequate or increased amounts of iron. Abnormal red blood cells called sideroblasts are found in the blood of people with these anemias. Sideroblastic anemias are classified as hereditary, acquired, and reversible.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sideroblastic Anemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Sideroblastic Anemia" returned 88 free, full-text research articles on human participants. First 3 results:

Transfer RNA and syndromic sideroblastic anemia.
 

Author(s): Achille Iolascon

Journal: Blood. 2014 Oct;124(18):2763-4.

 

Last Updated: 31 Oct 2014

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Heterozygous missense mutations in the GLRX5 gene cause sideroblastic anemia in a Chinese patient.
 

Author(s): Gang Liu, Shanshan Guo, Gregory J Anderson, Clara Camaschella, Bing Han, Guangjun Nie

Journal: Blood. 2014 Oct;124(17):2750-1.

 

Last Updated: 24 Oct 2014

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Mutations in TRNT1 cause congenital sideroblastic anemia with immunodeficiency, fevers, and developmental delay (SIFD).
 

Author(s): Pranesh K Chakraborty, Klaus Schmitz-Abe, Erin K Kennedy, Hapsatou Mamady, Turaya Naas, Danielle Durie, Dean R Campagna, Ashley Lau, Anoop K Sendamarai, Daniel H Wiseman, Alison May, Stephen Jolles, Philip Connor, Colin Powell, Matthew M Heeney, Patricia-Jane Giardina, Robert J Klaassen, Caroline Kannengiesser, Isabelle Thuret, Alexis A Thompson, Laura Marques, Stephen Hughes, Denise K Bonney, Sylvia S Bottomley, Robert F Wynn, Ronald M Laxer, Caterina P Minniti, John Moppett, Victoria Bordon, Michael Geraghty, Paul B M Joyce, Kyriacos Markianos, Adam D Rudner, Martin Holcik, Mark D Fleming

Journal: Blood. 2014 Oct;124(18):2867-71.

 

Mutations in genes encoding proteins that are involved in mitochondrial heme synthesis, iron-sulfur cluster biogenesis, and mitochondrial protein synthesis have previously been implicated in the pathogenesis of the congenital sideroblastic anemias (CSAs). We recently described a syndromic ...

Last Updated: 31 Oct 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Sideroblastic Anemia" returned 2 free, full-text review articles on human participants. First 3 results:

Idiopathic refractory sideroblastic anemia: incidence and risk factors for leukemic transformation.
 

Author(s): D S Cheng, J P Kushner, M M Wintrobe

Journal: Cancer. 1979 Aug;44(2):724-31.

 

The clinical course of 29 patients with idiopathic refractory sideroblastic anemia studied by us was reviewed. Four patients developed acute leukemia. We were able to find 27 out of 268 cases of idiopathic refractory sideroblastic anemia reported in the literature which terminated ...

Last Updated: 21 Nov 1979

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Idiopathic acquired sideroblastic anemia terminating in acute myelofibrosis: case report and review of leterature.
 

Author(s): K Yeung, A A Trowbridge

Journal: Cancer. 1977 Jan;39(1):359-65.

 

Acute myelofibrosis is a rare but distinct accelerated variant of agnogenic myeloid metaplasia that is characterized by marked anemia, peripheral blood myeloblastosis and normoblastosis, a lack of teardrop poikilocytosis, and prominent myelofibrosis. There is usually no palpable hepatosplenomegaly ...

Last Updated: 15 Mar 1977

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.