Sideroblastic Anemia

Common Name(s)

Sideroblastic Anemia

Sideroblastic anemia is a heterogeneous group of blood disorders characterized by an impaired ability of the bone marrow to produce normal red blood cells. The iron inside red blood cells is inadequately used to make hemoglobin, despite adequate or increased amounts of iron. Abnormal red blood cells called sideroblasts are found in the blood of people with these anemias. Sideroblastic anemias are classified as hereditary, acquired, and reversible.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sideroblastic Anemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sideroblastic Anemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Sideroblastic Anemia" returned 92 free, full-text research articles on human participants. First 3 results:

Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia.
 

Author(s): J Pedro Fernández-Murray, Sergey V Prykhozhij, J Noelia Dufay, Shelby L Steele, Daniel Gaston, Gheyath K Nasrallah, Andrew J Coombs, Robert S Liwski, Conrad V Fernandez, Jason N Berman, Christopher R McMaster

Journal:

 

Sideroblastic anemias are acquired or inherited anemias that result in a decreased ability to synthesize hemoglobin in red blood cells and result in the presence of iron deposits in the mitochondria of red blood cell precursors. A common subtype of congenital sideroblastic anemia ...

Last Updated: 29 Jan 2016

Go To URL
Mutation analysis of Chinese sporadic congenital sideroblastic anemia by targeted capture sequencing.
 

Author(s): Wenbin An, Jingliao Zhang, Lixian Chang, Yingchi Zhang, Yang Wan, Yuanyuan Ren, Deyun Niu, Jian Wu, Xiaofan Zhu, Ye Guo

Journal:

 

Congenital sideroblastic anemias (CSAs) comprise a group of heterogenous genetic diseases that are caused by the mutation of various genes involved in heme biosynthesis, iron-sulfur cluster biogenesis, or mitochondrial solute transport or metabolism. However, approximately 40% of ...

Last Updated: 24 May 2015

Go To URL
Transfer RNA and syndromic sideroblastic anemia.
 

Author(s): Achille Iolascon

Journal: Blood. 2014 Oct;124(18):2763-4.

 

Last Updated: 31 Oct 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Sideroblastic Anemia" returned 2 free, full-text review articles on human participants. First 3 results:

Idiopathic refractory sideroblastic anemia: incidence and risk factors for leukemic transformation.
 

Author(s): D S Cheng, J P Kushner, M M Wintrobe

Journal: Cancer. 1979 Aug;44(2):724-31.

 

The clinical course of 29 patients with idiopathic refractory sideroblastic anemia studied by us was reviewed. Four patients developed acute leukemia. We were able to find 27 out of 268 cases of idiopathic refractory sideroblastic anemia reported in the literature which terminated ...

Last Updated: 21 Nov 1979

Go To URL
Idiopathic acquired sideroblastic anemia terminating in acute myelofibrosis: case report and review of leterature.
 

Author(s): K Yeung, A A Trowbridge

Journal: Cancer. 1977 Jan;39(1):359-65.

 

Acute myelofibrosis is a rare but distinct accelerated variant of agnogenic myeloid metaplasia that is characterized by marked anemia, peripheral blood myeloblastosis and normoblastosis, a lack of teardrop poikilocytosis, and prominent myelofibrosis. There is usually no palpable hepatosplenomegaly ...

Last Updated: 15 Mar 1977

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.