Atrioventricular septal defect

Common Name(s)

Atrioventricular septal defect

Atrioventricular septal defects (AVSD) are a group of heart defects present at birth (congenital). Normally the four heart chambers are separated by walls (septum) to keep oxygen rich and oxygen poor blood separate. The blood flow between the chambers is controlled by valves. AVSDs are caused by a hole being present in the upper chambers (atrium) which allows a mixing of blood. AVSDs may also include defects in the AV valves. These birth defects cause the heart to send too much blood to the lungs. The overworked heart enlarges and causes the blood pressure in the lungs to become too high. Ultimately, an AVSD can lead to heart failure.

Common symptoms include difficulty breathing, abnormal heartbeats (arrhythmia), and poor blood circulation, which can cause bluish lips and skin and swelling in the legs (edema). Children with an AVSD may also have poor appetite and become tired easily. Sometimes symptoms may not appear for weeks or months after birth. The causes of AVSDs are believed to be a combination of genetics and environment. Babies with Down syndrome are at an increased risk for developing the condition. Other risk factors include the mother drinking alcohol during pregnancy or poorly controlled maternal diabetes.

Doctors may hear a swishing sound in the heartbeat (a murmur) when listening with a stethoscope. Tests used to confirm a VSD may include a chest X-ray, electrocardiogram (EKG) (tests the electrical impulses), echocardiogram (used sound waves to create a picture), or cardiac MRI.

Smaller defects may close on their own, but the most common treatment is surgical repair. If your baby or child has been diagnosed with an AVSD, talk to their pediatric cardiologist (a heart doctor for children) about the most current treatment options. Support organizations and genetic counselors are also a good source of information and can help connect you with others affected by AVSDs.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Atrioventricular septal defect" for support, advocacy or research.

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Atrioventricular septal defect" for support, advocacy or research.

Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Atrioventricular septal defect" returned 102 free, full-text research articles on human participants. First 3 results:

Surgical repair of a complete atrioventricular septal defect with tetralogy of Fallot using a classical one-patch technique and pulmonary valve preservation.
 

Author(s): Carine Pavy, Olivier Ghez

Journal:

 

The association of complete atrial ventricular septal defect (cAVSD) with tetralogy of Fallot remains a complex malformation that involves both inlet and outlet components of the ventricles. The surgical treatment used to be, in the 1980s, a staged repair strategy due to the high ...

Last Updated: 20 Jan 2017

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Accessory Mitral Valve Leaflet Causing Severe Left Ventricular Outflow Tract Obstruction in a Preterm Neonate with a Partial Atrioventricular Septal Defect.
 

Author(s): J Kevin Wilkes, Charles D Fraser, Thomas J Seery

Journal:

 

Atrioventricular septal defects represent a class of congenital cardiac malformations that vary in presentation and management strategy depending upon the severity of the particular lesions present. We present the case of a premature neonate who had a partial atrioventricular septal ...

Last Updated: 19 Jan 2017

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Transesophageal echocardiography in an atrioventricular septal defect.
 

Author(s): Rohan Magoon, Arindam Choudhury, Amita Sharma, Poonam Malhotra Kapoor

Journal: Ann Card Anaesth. ;19(4):587-588.

 

Last Updated: 7 Oct 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Atrioventricular septal defect" returned 5 free, full-text review articles on human participants. First 3 results:

Complete atrioventricular septal defect in the era of prenatal diagnosis.
 

Author(s): Daniel Mureşan, Claudiu Mărginean, Gabriela Zaharie, Florin Stamatian, Ioana Cristina Rotar

Journal: Med Ultrason. 2016 Dec;18(4):500-507.

 

Complete atrioventricular septal defect (CAVSD) is a fetal cardiac malformation (5% of all cardiac malformations) that can be detected prenatally with a reserved prognosis. The diagnosis can be suspected early at the end of the first trimester using the transabdominal or transvaginal ...

Last Updated: 16 Dec 2016

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Down Syndrome with Complete Atrioventricular Septal Defect, Hypertrophic Cardiomyopathy, and Pulmonary Vein Stenosis.
 

Author(s): Guruprasad Mahadevaiah, Manoj Gupta, Ravi Ashwath

Journal:

 

The prevalence of congenital heart disease in infants with Down syndrome is 40%, compared with 0.3% in children who have normal chromosomes. Atrioventricular and ventricular septal defects are often associated with chromosomal aberrations, such as in trisomy 21, whereas hypertrophic ...

Last Updated: 27 Oct 2015

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[The ostium primum or partial atrioventricular septal defect].
 

Author(s): M A Radermecker, R Fontaine, R Limet

Journal: Rev Med Liege. 2007 Jan;62(1):25-8.

 

Often assimilated to simple inter-atrial communication, the ostium primum, or partial atrio-ventricular septal defect, is an entity that is characterized by a different embryological mechanism and requires some specific surgical expertise. Basically, knowledge of the morphology of ...

Last Updated: 8 Mar 2007

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Mesoblast Stem Cell Therapy for Patients With Single Ventricle and Borderline Left Ventricle
 

Status: Not yet recruiting

Condition Summary: Hypoplastic Left Heart Syndrome; Atrioventricular Canal

 

Last Updated: 5 Oct 2017

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