Short Stature

Common Name(s)

Short Stature

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Short Stature" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Short Stature" returned 293 free, full-text research articles on human participants. First 3 results:

Height-reducing variants and selection for short stature in Sardinia.
 

Author(s): Magdalena Zoledziewska, Carlo Sidore, Charleston W K Chiang, Serena Sanna, Antonella Mulas, Maristella Steri, Fabio Busonero, Joseph H Marcus, Michele Marongiu, Andrea Maschio, Diego Ortega Del Vecchyo, Matteo Floris, Antonella Meloni, Alessandro Delitala, Maria Pina Concas, Federico Murgia, Ginevra Biino, Simona Vaccargiu, Ramaiah Nagaraja, Kirk E Lohmueller, , Nicholas J Timpson, Nicole Soranzo, Ioanna Tachmazidou, George Dedoussis, Eleftheria Zeggini, , Sergio Uzzau, Chris Jones, Robert Lyons, Andrea Angius, Gonçalo R Abecasis, John Novembre, David Schlessinger, Francesco Cucca

Journal: Nat. Genet.. 2015 Nov;47(11):1352-6.

 

We report sequencing-based whole-genome association analyses to evaluate the impact of rare and founder variants on stature in 6,307 individuals on the island of Sardinia. We identify two variants with large effects. One variant, which introduces a stop codon in the GHR gene, is relatively ...

Last Updated: 28 Oct 2015

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A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly.
 

Author(s): Baroj Abdulkarim, Marc Nicolino, Mariana Igoillo-Esteve, Mathilde Daures, Sophie Romero, Anne Philippi, Valérie Senée, Miguel Lopes, Daniel A Cunha, Heather P Harding, Céline Derbois, Nathalie Bendelac, Andrew T Hattersley, Décio L Eizirik, David Ron, Miriam Cnop, Cécile Julier

Journal: Diabetes. 2015 Nov;64(11):3951-62.

 

Dysregulated endoplasmic reticulum stress and phosphorylation of eukaryotic translation initiation factor 2α (eIF2α) are associated with pancreatic β-cell failure and diabetes. Here, we report the first homozygous mutation in the PPP1R15B gene (also known as constitutive repressor ...

Last Updated: 23 Oct 2015

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[Characteristics of R bone age, C bone age, and T bone age in children with different causes of short stature based on Tanner and Whitehouse skeletal age assessment system 2].
 

Author(s): Yun-Pu Cui, Ming-Tao Zhang, Xin-Li Wang

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2015 May;17(5):464-8.

 

To study the characteristics of R bone age, C bone age, and T bone age in children with different causes of short stature based on the Tanner and Whitehouse skeletal age assessment system 2 (TW2), and to provide a reference for the etiological diagnosis of short stature.

Last Updated: 27 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Short Stature" returned 34 free, full-text review articles on human participants. First 3 results:

Genetic evaluation of short stature.
 

Author(s): Andrew Dauber, Ron G Rosenfeld, Joel N Hirschhorn

Journal: J. Clin. Endocrinol. Metab.. 2014 Sep;99(9):3080-92.

 

Genetics plays a major role in determining an individual's height. Although there are many monogenic disorders that lead to perturbations in growth and result in short stature, there is still no consensus as to the role that genetic diagnostics should play in the evaluation of a child ...

Last Updated: 6 Sep 2014

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The etiology of short stature affects the clinical outcome of lower limb lengthening using external fixation. A systematic review of 18 trials involving 547 patients.
 

Author(s): Seung-Ju Kim, Wendy Pierce, Sanjeev Sabharwal

Journal: Acta Orthop. 2014 Apr;85(2):181-6.

 

Distraction osteogenesis (DO) has been used to gain height in short statured individuals. However, there have been no studies comparing the clinical outcome of limb lengthening based on the etiology of the short stature. We assessed whether different underlying diagnoses are associated ...

Last Updated: 21 Mar 2014

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Syndromic disorders with short stature.
 

Author(s): Zeynep Şıklar, Merih Berberoğlu

Journal: J Clin Res Pediatr Endocrinol. 2014 ;6(1):1-8.

 

Short stature is one of the major components of many dysmorphic syndromes. Growth failure may be due to a wide variety of mechanisms, either related to the growth hormone (GH)/insulin-like growth factor axis or to underlying unknown pathologies. In this review, the relatively more ...

Last Updated: 18 Mar 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Role of Igf-1 Generation Test in Diagnosis and Treatment of Short Stature
 

Status: Not yet recruiting

Condition Summary: Short Stature

 

Last Updated: 25 Oct 2013

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Short Stature Related Distress
 

Status: Recruiting

Condition Summary: Idiopathic Short Stature; Self Image

 

Last Updated: 26 Nov 2015

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IGF-1 Treatment for Individuals With Short Stature Due to PAPP-A2 Deficiency
 

Status: Not yet recruiting

Condition Summary: Short Stature

 

Last Updated: 16 Dec 2015

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