Short bowel syndrome

Common Name(s)

Short bowel syndrome

Short bowel syndrome is a group of problems involving the small intestine that causes poor absorption of nutrients from food. The main cause of short bowel syndrome is surgical removal of half or more of the small intestine to treat intestinal diseases, injuries, or defects present at birth. Signs and symptoms may include diarrhea, cramping, bloating, heartburn, dehydration, malnutrition, weight loss, food sensitivities, weakness, and fatigue. Examples of treatment include diet and nutritional support, and in some cases intestinal transplantation.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Short bowel syndrome" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Short bowel syndrome" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Short bowel syndrome" returned 119 free, full-text research articles on human participants. First 3 results:

Is jejunostomy output nutrient or waste in short bowel syndrome? Experience from six cases.
 

Author(s): Ming-Yi Liu, Hsiu-Chih Tang, Hui-Lan Yang, Sue-Joan Chang

Journal: Asia Pac J Clin Nutr. 2016 ;25(2):430-5.

 

Certain patients who undergo proximal jejunum resection are unable to undergo primary anastomosis and require exteriorization of the proximal jejunum. These patients usually have major problems with short bowel due to the high output of the stoma. The output of a proximal jejunostomy ...

Last Updated: 25 May 2016

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Faecal short-chain fatty acids - a diagnostic biomarker for irritable bowel syndrome?
 

Author(s): Per G Farup, Knut Rudi, Knut Hestad

Journal:

 

The diagnosis of irritable bowel syndrome (IBS) relies on symptom-based criteria. A valid and reliable biomarker that could confirm the diagnosis is desirable. This study evaluated the properties of faecal short-chain fatty acids (SCFA) as diagnostic biomarkers for IBS.

Last Updated: 28 Apr 2016

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A potential anatomic subtype of short bowel syndrome: a matched case-control study.
 

Author(s): Wencheng Kong, Jian Wang, Rongchao Ying, Yousheng Li, Huicheng Jin, Qi Mao, Danhua Yao, Mingxiao Guo

Journal:

 

Fundamental researches suggest that ileum presents greater adaptive potential than the jejunum. However, few studies estimate the association between ileum and adaptive potential in human. To discover the association, we conducted this matched case-control study.

Last Updated: 29 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Short bowel syndrome" returned 22 free, full-text review articles on human participants. First 3 results:

Animal models of gastrointestinal and liver diseases. Animal models of infant short bowel syndrome: translational relevance and challenges.
 

Author(s): Per T Sangild, Denise M Ney, David L Sigalet, Andreas Vegge, Douglas Burrin

Journal: Am. J. Physiol. Gastrointest. Liver Physiol.. 2014 Dec;307(12):G1147-68.

 

Intestinal failure (IF), due to short bowel syndrome (SBS), results from surgical resection of a major portion of the intestine, leading to reduced nutrient absorption and need for parenteral nutrition (PN). The incidence is highest in infants and relates to preterm birth, necrotizing ...

Last Updated: 16 Dec 2014

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Surgical options to enhance intestinal function in patients with short bowel syndrome.
 

Author(s): Josh Sommovilla, Brad W Warner

Journal: Curr. Opin. Pediatr.. 2014 Jun;26(3):350-5.

 

This review will provide the practitioner with an understanding of the spectrum of nontransplant surgical options for managing patients with short bowel syndrome (SBS).

Last Updated: 6 May 2014

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Role of probiotics in short bowel syndrome in infants and children--a systematic review.
 

Author(s): Vudum S Reddy, Sanjay K Patole, Shripada Rao

Journal:

 

Short bowel syndrome (SBS) is a cause of significant morbidity and mortality in children. Probiotics, due to their beneficial effects on the gastrointestinal tract (e.g., improving gut barrier function, motility, facilitation of intestinal adaptation and decreasing pathogen load and ...

Last Updated: 6 Mar 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Use of DPP-4 Inhibitors in Short Bowel Syndrome
 

Status: Recruiting

Condition Summary: Short Bowel Syndrome

 

Last Updated: 5 Dec 2016

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A Prospective, Multi-center Registry for Patients With Short Bowel Syndrome
 

Status: Recruiting

Condition Summary: Short Bowel Syndrome

 

Last Updated: 5 Jan 2017

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Short Bowel Syndrome Research Study for Children Up To 17 Years of Age on Parenteral Nutrition
 

Status: Recruiting

Condition Summary: Short Bowel Syndrome

 

Last Updated: 13 Jan 2017

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