Short bowel syndrome

Common Name(s)

Short bowel syndrome

Short bowel syndrome is a group of problems involving the small intestine that causes poor absorption of nutrients from food. The main cause of short bowel syndrome is surgical removal of half or more of the small intestine to treat intestinal diseases, injuries, or defects present at birth. Signs and symptoms may include diarrhea, cramping, bloating, heartburn, dehydration, malnutrition, weight loss, food sensitivities, weakness, and fatigue. Examples of treatment include diet and nutritional support, and in some cases intestinal transplantation.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Short bowel syndrome" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Short bowel syndrome" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Short bowel syndrome" returned 123 free, full-text research articles on human participants. First 3 results:

[Intestinal failure due to short bowel syndrome: impact of a multidisciplinary intestinal rehabilitation program].
 

Author(s): María Elena Molina, Felipe Bellolio, Julieta Klaassen, Javier Gómez, Constanza Villalón, Juan Francisco Guerra, Álvaro Zúñiga

Journal: Rev Med Chil. 2016 Nov;144(11):1410-1416.

 

In patients suffering intestinal failure due to short bowel, the goal of an Intestinal Rehabilitation Program is to optimize and tailor all aspects of clinical management, and eventually, wean patients off lifelong parenteral nutrition.

Last Updated: 10 Apr 2017

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Outcomes from a 12-Week, Open-Label, Multicenter Clinical Trial of Teduglutide in Pediatric Short Bowel Syndrome.
 

Author(s): Beth A Carter, Valeria C Cohran, Conrad R Cole, Mark R Corkins, Reed A Dimmitt, Christopher Duggan, Susan Hill, Simon Horslen, Joel D Lim, David F Mercer, Russell J Merritt, Peter F Nichol, Luther Sigurdsson, Daniel H Teitelbaum, John Thompson, Charles Vanderpool, Juliana F Vaughan, Benjamin Li, Nader N Youssef, Robert S Venick, Samuel A Kocoshis

Journal: J. Pediatr.. 2017 Feb;181():102-111.e5.

 

To determine safety and pharmacodynamics/efficacy of teduglutide in children with intestinal failure associated with short bowel syndrome (SBS-IF).

Last Updated: 18 Nov 2016

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Therapeutic Drug Monitoring of Anti-human Immunodeficiency Virus Drugs in a Patient with Short Bowel Syndrome.
 

Author(s): Motoko Ikuma, Dai Watanabe, Hiroki Yagura, Misa Ashida, Masaaki Takahashi, Masaaki Shibata, Tadafumi Asaoka, Munehiro Yoshino, Tomoko Uehira, Wataru Sugiura, Takuma Shirasaka

Journal: Intern. Med.. ;55(20):3059-3063.

 

An elderly woman with human immunodeficiency virus-1 infection developed short bowel syndrome as a result of extensive intestinal resection. Considering the possibility of poor absorption of antiretroviral drugs (ARVs), therapeutic drug monitoring (TDM) was performed. A single-dose ...

Last Updated: 17 Oct 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Short bowel syndrome" returned 23 free, full-text review articles on human participants. First 3 results:

Treatment of short bowel syndrome in children. Value of the Intestinal Rehabilitation Program.
 

Author(s): Uenis Tannuri, Fabio de Barros, Ana Cristina Aoun Tannuri

Journal: Rev Assoc Med Bras (1992). 2016 Sep;62(6):575-583.

 

The main cause of acute intestinal failure is short bowel syndrome, generally as a result of resection of extensive segments of small intestine. As a result, the main symptoms are watery diarrhea, malabsorption syndrome, chronic malnutrition, and death, if the patient is not properly ...

Last Updated: 16 Nov 2016

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Generation of an artificial intestine for the management of short bowel syndrome.
 

Author(s): Mitchell R Ladd, Diego F Niño, John C March, Chhinder P Sodhi, David J Hackam

Journal: Curr Opin Organ Transplant. 2016 Apr;21(2):178-85.

 

This article discusses the current state of the art in artificial intestine generation in the treatment of short bowel syndrome.

Last Updated: 11 Mar 2016

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Animal models of gastrointestinal and liver diseases. Animal models of infant short bowel syndrome: translational relevance and challenges.
 

Author(s): Per T Sangild, Denise M Ney, David L Sigalet, Andreas Vegge, Douglas Burrin

Journal: Am. J. Physiol. Gastrointest. Liver Physiol.. 2014 Dec;307(12):G1147-68.

 

Intestinal failure (IF), due to short bowel syndrome (SBS), results from surgical resection of a major portion of the intestine, leading to reduced nutrient absorption and need for parenteral nutrition (PN). The incidence is highest in infants and relates to preterm birth, necrotizing ...

Last Updated: 16 Dec 2014

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Use of DPP-4 Inhibitors in Short Bowel Syndrome
 

Status: Recruiting

Condition Summary: Short Bowel Syndrome

 

Last Updated: 5 Dec 2016

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A Prospective, Multi-center Registry for Patients With Short Bowel Syndrome
 

Status: Recruiting

Condition Summary: Short Bowel Syndrome

 

Last Updated: 5 Jan 2017

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Use of Pancreatic Enzymes in Short Bowel Syndrome
 

Status: Recruiting

Condition Summary: Short Bowel Syndrome

 

Last Updated: 14 Aug 2017

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