Shigellosis

Common Name(s)

Shigellosis

Shigellosis is a contagious illness caused by the Shigella bacterium. There are four different types of Shigella which cause diarrhea. The bacteria are present in the fecal matter (bowel movement) of infected individuals. Shigella bacteria are often spread by touching contaminated hands to the mouth, by eating/drinking contaminated food or water, or through person to person contact. Shigella cannot live outside the body for long. Children, childcare workers, and those with weak immune systems are the most likely to be infected. However, not all infected people develop symptoms.

Symptoms of shigellosis begin 1 to 2 days after exposure to the bacteria and may include fever, diarrhea, and stomach cramps. Symptoms generally last 5 to 7 days. Shigellosis may be difficult to diagnose because the symptoms are common to other illnesses. Lab tests of the stool or fecal matter can determine the bacteria type and if antibiotics will help.

Complications include post-infectious arthritis, blood stream infections, seizures, and hemolytic-uremic syndrome. Post-infectious arthritis symptoms include joint pain, eye irritation, and painful urination, which may last only a few months or may be permanent. Blood stream infections usually occur in individuals with weak immune systems by germs entering the blood stream through damaged lining of the intestines. Children with a high fever may experience seizures. Hemolytic-uremic syndrome occurs when bacteria in the digestive system produce toxins to destroy red blood cells, causing bloody diarrhea.

Treatment for shigellosis includes drinking fluids and rest. In most cases, the body will clear the bacterial infection on its own. Antibiotics may be used in severe cases, although some Shigella bacteria are resistant. Common hygiene methods such as washing hands with soap can reduce the spread of shigellosis. If you are suffering from shigellosis, talk to your doctor about the most current treatment options.

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Condition Specific Organizations

Following organizations serve the condition "Shigellosis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Shigellosis" returned 159 free, full-text research articles on human participants. First 3 results:

Functional and Antigen-Specific Serum Antibody Levels as Correlates of Protection against Shigellosis in a Controlled Human Challenge Study.
 

Author(s): Avital A Shimanovich, Amanda D Buskirk, Shannon J Heine, William C Blackwelder, Rezwanul Wahid, Karen L Kotloff, Marcela F Pasetti

Journal:

 

Shigella is an important cause of diarrheal disease in young children living in developing countries. No approved vaccines are available, and the development of vaccine candidates has been hindered by the lack of firm immunological correlates of protection, among other reasons. To ...

Last Updated: 8 Dec 2016

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Shigellosis in Nepal: 13 years review of nationwide surveillance.
 

Author(s): Geeta Shakya, Jyoti Acharya, Shailaja Adhikari, Nisha Rijal

Journal:

 

Shigella is a major cause of gastroenteritis especially in children. In developing countries, the incidence is frequent and results are often life threatening. Changing epidemiology and emerging antibiotic resistance warrants continuous monitoring of susceptibility. The present study ...

Last Updated: 5 Nov 2016

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Notes from the Field: Shigellosis Outbreak Among Men Who Have Sex with Men and Homeless Persons - Oregon, 2015-2016.
 

Author(s): Jonas Z Hines, Taylor Pinsent, Kathleen Rees, Jennifer Vines, Anna Bowen, Jacqueline Hurd, Richard F Leman, Katrina Hedberg

Journal:

 

In July 2015, Shigella sonnei infections with a specific pulsed-field gel electrophoresis (PFGE) pattern linked to a multistate outbreak were recognized among men who have sex with men (MSM) in the Portland metropolitan area, and an outbreak investigation was initiated. During November ...

Last Updated: 12 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Shigellosis" returned 9 free, full-text review articles on human participants. First 3 results:

Shigellosis: Epidemiology in India.
 

Author(s): Neelam Taneja, Abhishek Mewara

Journal: Indian J. Med. Res.. 2016 May;143(5):565-76.

 

Shigellosis is one of the major causes of diarrhoea in India. The accurate estimates of morbidity and mortality due to shigellosis are lacking, though it is endemic in the country and has been reported to cause many outbreaks. The limited information available indicates Shigella to ...

Last Updated: 4 Aug 2016

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Causative species and serotypes of shigellosis in mainland China: systematic review and meta-analysis.
 

Author(s): Zhili Chang, Shuting Lu, Lihong Chen, Qi Jin, Jian Yang

Journal: PLoS ONE. 2012 ;7(12):e52515.

 

Shigella, the causative agent of shigellosis, is a major global public health concern, particularly in developing countries with poor sanitation. A comprehensive and current understanding of the prevalent species and serotypes of shigellosis is essential for both disease prevention ...

Last Updated: 3 Jan 2013

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Decrease in shigellosis-related deaths without Shigella spp.-specific interventions, Asia.
 

Author(s): Pradip Bardhan, A S G Faruque, Aliya Naheed, David A Sack

Journal: Emerging Infect. Dis.. 2010 Nov;16(11):1718-23.

 

In 1999, a review of the literature for 1966-1997 suggested that ≈1.1 million persons die annually of shigellosis, including ≈880,000 in Asia. Our recent review of the literature for 1990-2009 indicates that ≈125 million shigellosis cases occur annually in Asia, of which ≈14,000 ...

Last Updated: 29 Oct 2010

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

SF2a-TT15 Conjugate Vaccine in Healthy Adult Volunteers
 

Status: Not yet recruiting

Condition Summary: Shigellosis; Bacillary Dysentery

 

Last Updated: 16 Jun 2016

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Phase 1 Study of dmLT ID Vaccination in Healthy Adults
 

Status: Recruiting

Condition Summary: Gastroenteritis Escherichia Coli

 

Last Updated: 12 Oct 2017

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