Seizures

Common Name(s)

Seizures, Epileptic seizure

Seizures occur when there is abnormal electrical activity in the brain. Chemical changes in our nerve cells trigger the electrical activity in our body. Brain cells either trigger or stop other brain cells from sending messages throughout the body. During a seizure there is either too much or too little activity going on in the brain cells. This causes the sudden electrical activity that leads to seizures. Since there are different types of seizures, the location of the abnormal activity in the brain sets one seizure apart from another.

Non-epileptic seizures are seizures that occur from injuries. In partial seizures, the abnormal activity occurs in only one side of the brain. This results in only one side of the body experiencing the seizure. Generalized seizures affect both sides of the brain. Each seizure has different symptoms. Brief blackout, twitching and jerking movements, sudden falling, shaking of the entire body, sudden eye movements, change in behavior, loss of bladder control, loss of speech control, and teeth clenching are a few symptoms of seizures.

Seizures are often a symptom of other health conditions. They may result from high fever, head injury, infections, trauma, stroke, drug abuse, electric shock, extremely high blood pressure, alcohol withdrawal, and drug withdrawal. Doctors diagnose seizures by running a test called electroencephalogram (EEG). This test checks the brain for unusual electrical activity. There are many types of medications available to treat this condition. If medication does not work, then surgery may be an option. Talk with your doctor to decide which treatment plan is best for you. Support groups are also good resources for support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Seizures" for support, advocacy or research.

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Epilepsy Foundation - Home Office

The mission of the Epilepsy Foundation is to stop seizures and SUDEP, find a cure and overcome the challenges created by epilepsy through efforts including education, advocacy and research to accelerate ideas into therapies.

Last Updated: 28 Apr 2015

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Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

Last Updated: 20 Jul 2015

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The Arc of East Central Iowa

The Arc of East Central Iowa empowers people with intellectual and related disabilities to engage in lifelong opportunities to live, learn, work and play with dignity, freedom and full inclusion in their communities.

Last Updated: 11 Apr 2013

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Zellweger Baby Support Network

This organization was started by a small group of parents whose lives have been affected in some way by a rare disorder. Our gift, in honor of our children, was to start this site, so we can help families and to raise awareness of these rare disorders. If your child has been diagnosed with Zellweger syndrome, a peroxisomal disorder or another rare disorder, we are here to help you. You are not alone! Our mission is to promote, advance, and improve awareness of Zellweger syndrome and other peroxisomal disorders, to assist, support, and aid, financially or otherwise, individuals and families affected by Zellweger syndrome. We will help you learn more about these disorders. We will provide emotional support, and we can help you to create a journal site for your child so that family and friends can be kept up to date on your child. We will pray with you and for you as you journey through life with your special angel. We know this is a hard time for you; you want answers, informa

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Seizures" for support, advocacy or research.

Logo
Epilepsy Foundation - Home Office

The mission of the Epilepsy Foundation is to stop seizures and SUDEP, find a cure and overcome the challenges created by epilepsy through efforts including education, advocacy and research to accelerate ideas into therapies.

http://www.epilepsy.com

Last Updated: 28 Apr 2015

View Details
Logo
Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

http://www.simonsvipconnect.org

Last Updated: 20 Jul 2015

View Details
The Arc of East Central Iowa

The Arc of East Central Iowa empowers people with intellectual and related disabilities to engage in lifelong opportunities to live, learn, work and play with dignity, freedom and full inclusion in their communities.

http://www.arceci.org

Last Updated: 11 Apr 2013

View Details
Logo
Zellweger Baby Support Network

This organization was started by a small group of parents whose lives have been affected in some way by a rare disorder. Our gift, in honor of our children, was to start this site, so we can help families and to raise awareness of these rare disorders. If your child has been diagnosed with Zellweger syndrome, a peroxisomal disorder or another rare disorder, we are here to help you. You are not alone! Our mission is to promote, advance, and improve awareness of Zellweger syndrome and other peroxisomal disorders, to assist, support, and aid, financially or otherwise, individuals and families affected by Zellweger syndrome. We will help you learn more about these disorders. We will provide emotional support, and we can help you to create a journal site for your child so that family and friends can be kept up to date on your child. We will pray with you and for you as you journey through life with your special angel. We know this is a hard time for you; you want answers, informa

http://www.zbsn.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Seizures" returned 2151 free, full-text research articles on human participants. First 3 results:

Seizures in Children and Adolescents Aged 6-17 Years - United States, 2010-2014.
 

Author(s): Wanjun Cui, Rosemarie Kobau, Matthew M Zack, Sandra Helmers, Marshalyn Yeargin-Allsopp

Journal:

 

Last Updated: 6 Nov 2015

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A noninterventional study evaluating the effectiveness and safety of lacosamide added to monotherapy in patients with epilepsy with partial-onset seizures in daily clinical practice: The VITOBA study.
 

Author(s): Uwe Runge, Stephan Arnold, Christian Brandt, Fritjof Reinhardt, Frank Kühn, Kathleen Isensee, Francisco Ramirez, Peter Dedeken, Thomas Lauterbach, Matthias Noack-Rink, Thomas Mayer

Journal: Epilepsia. 2015 Dec;56(12):1921-30.

 

Evidence for the efficacy and safety of adjunctive lacosamide in the treatment of partial-onset seizures (POS) was gained during placebo-controlled clinical trials in patients with treatment-resistant seizures who were taking one to three concomitant antiepileptic drugs (AEDs). The ...

Last Updated: 15 Dec 2015

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Critical Roles of the Direct GABAergic Pallido-cortical Pathway in Controlling Absence Seizures.
 

Author(s): Mingming Chen, Daqing Guo, Min Li, Tao Ma, Shengdun Wu, Jingling Ma, Yan Cui, Yang Xia, Peng Xu, Dezhong Yao

Journal:

 

The basal ganglia (BG), serving as an intermediate bridge between the cerebral cortex and thalamus, are believed to play crucial roles in controlling absence seizure activities generated by the pathological corticothalamic system. Inspired by recent experiments, here we systematically ...

Last Updated: 27 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Seizures" returned 276 free, full-text review articles on human participants. First 3 results:

Treatment for psychogenic non-epileptic seizures.
 

Author(s): Mia Tuft, Hilde Nordahl Karterud, Antonia Villagran, Karl O Nakken

Journal:

 

The main differential diagnosis of epilepsy among young adults is psychogenic non-epileptic seizures. Such seizures may manifest themselves in very different ways and usually have complex root causes. Optimal treatment of persons experiencing seizures of this type requires close cooperation ...

Last Updated: 11 Sep 2015

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Clinical Management of Seizures in Patients With Low-Grade Glioma.
 

Author(s): Anna F Piotrowski, Jaishri Blakeley

Journal: Semin Radiat Oncol. 2015 Jul;25(3):219-24.

 

Seizures, transient disruptions of normal brain electrical activity, are common for patients with low-grade glioma (LGG) and significantly affect quality of life. Up to 75% of patients with a LGG will have seizures in the course of their disease (compared with 1%-2% of the general ...

Last Updated: 8 Jun 2015

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Cardiac arrhythmias during or after epileptic seizures.
 

Author(s): Marije van der Lende, Rainer Surges, Josemir W Sander, Roland D Thijs

Journal: J. Neurol. Neurosurg. Psychiatr.. 2016 Jan;87(1):69-74.

 

Seizure-related cardiac arrhythmias are frequently reported and have been implicated as potential pathomechanisms of Sudden Unexpected Death in Epilepsy (SUDEP). We attempted to identify clinical profiles associated with various (post)ictal cardiac arrhythmias. We conducted a systematic ...

Last Updated: 18 Dec 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Remegal Fixed Dose as Adjunctive Therapy in Patients With Partial Seizures
 

Status: Recruiting

Condition Summary: Epilepsy; Simple Partial Seizures; Complex Partial Seizures; Partial Seizures With Secondary Generalization

 

Last Updated: 11 Dec 2012

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Respiratory Physiology in Children With Febrile Seizures.
 

Status: Recruiting

Condition Summary: Febrile Illness in Children; Seizures, Febrile

 

Last Updated: 23 Jul 2013

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