Seizures

Common Name(s)

Seizures, Epileptic seizure

Seizures occur when there is abnormal electrical activity in the brain. Chemical changes in our nerve cells trigger the electrical activity in our body. Brain cells either trigger or stop other brain cells from sending messages throughout the body. During a seizure there is either too much or too little activity going on in the brain cells. This causes the sudden electrical activity that leads to seizures. Since there are different types of seizures, the location of the abnormal activity in the brain sets one seizure apart from another.

Non-epileptic seizures are seizures that occur from injuries. In partial seizures, the abnormal activity occurs in only one side of the brain. This results in only one side of the body experiencing the seizure. Generalized seizures affect both sides of the brain. Each seizure has different symptoms. Brief blackout, twitching and jerking movements, sudden falling, shaking of the entire body, sudden eye movements, change in behavior, loss of bladder control, loss of speech control, and teeth clenching are a few symptoms of seizures.

Seizures are often a symptom of other health conditions. They may result from high fever, head injury, infections, trauma, stroke, drug abuse, electric shock, extremely high blood pressure, alcohol withdrawal, and drug withdrawal. Doctors diagnose seizures by running a test called electroencephalogram (EEG). This test checks the brain for unusual electrical activity. There are many types of medications available to treat this condition. If medication does not work, then surgery may be an option. Talk with your doctor to decide which treatment plan is best for you. Support groups are also good resources for support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Seizures" for support, advocacy or research.

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Epilepsy Foundation - Home Office

The mission of the Epilepsy Foundation is to stop seizures and SUDEP, find a cure and overcome the challenges created by epilepsy through efforts including education, advocacy and research to accelerate ideas into therapies.

Last Updated: 28 Apr 2015

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Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

Last Updated: 20 Jul 2015

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The Arc of East Central Iowa

The Arc of East Central Iowa empowers people with intellectual and related disabilities to engage in lifelong opportunities to live, learn, work and play with dignity, freedom and full inclusion in their communities.

Last Updated: 11 Apr 2013

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Zellweger Baby Support Network

This organization was started by a small group of parents whose lives have been affected in some way by a rare disorder. Our gift, in honor of our children, was to start this site, so we can help families and to raise awareness of these rare disorders. If your child has been diagnosed with Zellweger syndrome, a peroxisomal disorder or another rare disorder, we are here to help you. You are not alone! Our mission is to promote, advance, and improve awareness of Zellweger syndrome and other peroxisomal disorders, to assist, support, and aid, financially or otherwise, individuals and families affected by Zellweger syndrome. We will help you learn more about these disorders. We will provide emotional support, and we can help you to create a journal site for your child so that family and friends can be kept up to date on your child. We will pray with you and for you as you journey through life with your special angel. We know this is a hard time for you; you want answers, informa

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Seizures" for support, advocacy or research.

Logo
Epilepsy Foundation - Home Office

The mission of the Epilepsy Foundation is to stop seizures and SUDEP, find a cure and overcome the challenges created by epilepsy through efforts including education, advocacy and research to accelerate ideas into therapies.

http://www.epilepsy.com

Last Updated: 28 Apr 2015

View Details
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Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

http://www.simonsvipconnect.org

Last Updated: 20 Jul 2015

View Details
The Arc of East Central Iowa

The Arc of East Central Iowa empowers people with intellectual and related disabilities to engage in lifelong opportunities to live, learn, work and play with dignity, freedom and full inclusion in their communities.

http://www.arceci.org

Last Updated: 11 Apr 2013

View Details
Logo
Zellweger Baby Support Network

This organization was started by a small group of parents whose lives have been affected in some way by a rare disorder. Our gift, in honor of our children, was to start this site, so we can help families and to raise awareness of these rare disorders. If your child has been diagnosed with Zellweger syndrome, a peroxisomal disorder or another rare disorder, we are here to help you. You are not alone! Our mission is to promote, advance, and improve awareness of Zellweger syndrome and other peroxisomal disorders, to assist, support, and aid, financially or otherwise, individuals and families affected by Zellweger syndrome. We will help you learn more about these disorders. We will provide emotional support, and we can help you to create a journal site for your child so that family and friends can be kept up to date on your child. We will pray with you and for you as you journey through life with your special angel. We know this is a hard time for you; you want answers, informa

http://www.zbsn.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Seizures" returned 2375 free, full-text research articles on human participants. First 3 results:

Profile and clinical characterization of seizures in hospitalized children.
 

Author(s): Ernestina Ernest Mwipopo, Shahnawaz Akhatar, Panpan Fan, Dongchi Zhao

Journal:

 

Seizure is the commonest pediatric neurological disorder, which is frightening to caretakers. The current study aims to determine profile, clinical spectrum and analyze the commonest etiology of seizures in children admitted to a tertiary hospital in Central China.

Last Updated: 3 Feb 2017

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Prevalence of non-febrile seizures in children with idiopathic autism spectrum disorder and their unaffected siblings: a retrospective cohort study.
 

Author(s): Lena M McCue, Louise H Flick, Kimberly A Twyman, Hong Xian, Thomas E Conturo

Journal:

 

Autism spectrum disorder (ASD) is a heterogeneous disorder characterized not only by deficits in communication and social interactions but also a high rate of co-occurring disorders, including metabolic abnormalities, gastrointestinal and sleep disorders, and seizures. Seizures, when ...

Last Updated: 29 Nov 2016

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Response to Zhang et al.: Levetiracetam vs. brivaracetam for adults with refractory focal seizures: A meta-analysis and indirect comparison.
 

Author(s): Simon Borghs, Mata Charokopou, Christian Brandt, Pavel Klein

Journal: Seizure. 2016 Oct;41():182-3.

 

Last Updated: 25 Sep 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Seizures" returned 310 free, full-text review articles on human participants. First 3 results:

Association between seizures after ischemic stroke and stroke outcome: A systematic review and meta-analysis.
 

Author(s): Tao Xu, Shu Ou, Xi Liu, Xinyuan Yu, Jinxian Yuan, Hao Huang, Yangmei Chen

Journal: Medicine (Baltimore). 2016 Jul;95(27):e4117.

 

A systematic review and meta-analysis were performed to investigate a potential association between post-ischemic stroke seizures (PISS) and subsequent ischemic stroke (IS) outcome.A systematic search of two electronic databases (Medline and Embase) was conducted to identify studies ...

Last Updated: 12 Jul 2016

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[Epilepsy and acute seizures in childhood in sub-Saharan Africa: challenges and hopes].
 

Author(s): CĂ©lestin Kaputu-Kalala-Malu

Journal:

 

Epilepsy is a neurological disease common among children in sub-Saharan Africa (SSA). Although its exact prevalence in this population is unknown, it is probably similar to that found in the general population because of its early onset (60% starts before the age of 20 years) and ...

Last Updated: 24 May 2016

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Atypical facial pain in multiple sclerosis caused by spinal cord seizures: a case report and review of the literature.
 

Author(s): Kunal Gupta, Kim J Burchiel

Journal:

 

Pain is a very commonly reported symptom and often drives patients to seek medical attention; however, it can prove a very difficult diagnostic conundrum and even more challenging to treat effectively. Accurately determining the primary pain generator is key, as certain conditions ...

Last Updated: 20 Apr 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Levetiracetam Treatment of Neonatal Seizures
 

Status: Recruiting

Condition Summary: Neonatal Seizures

 

Last Updated: 15 Dec 2016

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Pilot Study of Bumetanide for Newborn Seizures
 

Status: Recruiting

Condition Summary: Seizures

 

Last Updated: 14 Oct 2016

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Treating Non-epileptic Seizures Using Magnetic Brain Stimulation
 

Status: Not yet recruiting

Condition Summary: Nonepileptic Seizures

 

Last Updated: 7 Jun 2016

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