Seizures

Common Name(s)

Seizures, Epileptic seizure

Seizures occur when there is abnormal electrical activity in the brain. Chemical changes in our nerve cells trigger the electrical activity in our body. Brain cells either trigger or stop other brain cells from sending messages throughout the body. During a seizure there is either too much or too little activity going on in the brain cells. This causes the sudden electrical activity that leads to seizures. Since there are different types of seizures, the location of the abnormal activity in the brain sets one seizure apart from another.

Non-epileptic seizures are seizures that occur from injuries. In partial seizures, the abnormal activity occurs in only one side of the brain. This results in only one side of the body experiencing the seizure. Generalized seizures affect both sides of the brain. Each seizure has different symptoms. Brief blackout, twitching and jerking movements, sudden falling, shaking of the entire body, sudden eye movements, change in behavior, loss of bladder control, loss of speech control, and teeth clenching are a few symptoms of seizures.

Seizures are often a symptom of other health conditions. They may result from high fever, head injury, infections, trauma, stroke, drug abuse, electric shock, extremely high blood pressure, alcohol withdrawal, and drug withdrawal. Doctors diagnose seizures by running a test called electroencephalogram (EEG). This test checks the brain for unusual electrical activity. There are many types of medications available to treat this condition. If medication does not work, then surgery may be an option. Talk with your doctor to decide which treatment plan is best for you. Support groups are also good resources for support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Seizures" for support, advocacy or research.

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Epilepsy Foundation - Home Office

The mission of the Epilepsy Foundation is to stop seizures and SUDEP, find a cure and overcome the challenges created by epilepsy through efforts including education, advocacy and research to accelerate ideas into therapies.

Last Updated: 28 Apr 2015

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Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

Last Updated: 20 Jul 2015

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The Arc of East Central Iowa

The Arc of East Central Iowa empowers people with intellectual and related disabilities to engage in lifelong opportunities to live, learn, work and play with dignity, freedom and full inclusion in their communities.

Last Updated: 11 Apr 2013

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Zellweger Baby Support Network

This organization was started by a small group of parents whose lives have been affected in some way by a rare disorder. Our gift, in honor of our children, was to start this site, so we can help families and to raise awareness of these rare disorders. If your child has been diagnosed with Zellweger syndrome, a peroxisomal disorder or another rare disorder, we are here to help you. You are not alone! Our mission is to promote, advance, and improve awareness of Zellweger syndrome and other peroxisomal disorders, to assist, support, and aid, financially or otherwise, individuals and families affected by Zellweger syndrome. We will help you learn more about these disorders. We will provide emotional support, and we can help you to create a journal site for your child so that family and friends can be kept up to date on your child. We will pray with you and for you as you journey through life with your special angel. We know this is a hard time for you; you want answers, informa

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Seizures" for support, advocacy or research.

Logo
Epilepsy Foundation - Home Office

The mission of the Epilepsy Foundation is to stop seizures and SUDEP, find a cure and overcome the challenges created by epilepsy through efforts including education, advocacy and research to accelerate ideas into therapies.

http://www.epilepsy.com

Last Updated: 28 Apr 2015

View Details
Logo
Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

http://www.simonsvipconnect.org

Last Updated: 20 Jul 2015

View Details
The Arc of East Central Iowa

The Arc of East Central Iowa empowers people with intellectual and related disabilities to engage in lifelong opportunities to live, learn, work and play with dignity, freedom and full inclusion in their communities.

http://www.arceci.org

Last Updated: 11 Apr 2013

View Details
Logo
Zellweger Baby Support Network

This organization was started by a small group of parents whose lives have been affected in some way by a rare disorder. Our gift, in honor of our children, was to start this site, so we can help families and to raise awareness of these rare disorders. If your child has been diagnosed with Zellweger syndrome, a peroxisomal disorder or another rare disorder, we are here to help you. You are not alone! Our mission is to promote, advance, and improve awareness of Zellweger syndrome and other peroxisomal disorders, to assist, support, and aid, financially or otherwise, individuals and families affected by Zellweger syndrome. We will help you learn more about these disorders. We will provide emotional support, and we can help you to create a journal site for your child so that family and friends can be kept up to date on your child. We will pray with you and for you as you journey through life with your special angel. We know this is a hard time for you; you want answers, informa

http://www.zbsn.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Seizures" returned 2239 free, full-text research articles on human participants. First 3 results:

Case report of an infant with severe vitamin D deficiency rickets manifested as hypocalcemic seizures.
 

Author(s): Biljana Vuletić, Slavica Marković, Zoran Igrutinović, Radlović Vladimir, Zorica Rasković, Aleksandra Simović

Journal: Srp Arh Celok Lek. ;144(1-2):90-3.

 

Hypocalcemic seizures are uncommon in the post-neonatal period. We report an infant with hypocalcemic seizures caused by severe deficiency of vitamin D.

Last Updated: 9 Jun 2016

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[Risk factors for 5-year recurrence of spontaneous symptomatic epileptic seizures in infants and young children].
 

Author(s): Li-Ya Zhang, Ji-Hong Tang, Yan Li

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2016 Apr;18(4):301-5.

 

To investigate the recurrence rate and risk factors of spontaneous symptomatic epileptic seizures after the first episode in infants and young children.

Last Updated: 21 Apr 2016

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The ictal wavefront is the spatiotemporal source of discharges during spontaneous human seizures.
 

Author(s): Elliot H Smith, Jyun-you Liou, Tyler S Davis, Edward M Merricks, Spencer S Kellis, Shennan A Weiss, Bradley Greger, Paul A House, Guy M McKhann, Robert R Goodman, Ronald G Emerson, Lisa M Bateman, Andrew J Trevelyan, Catherine A Schevon

Journal:

 

The extensive distribution and simultaneous termination of seizures across cortical areas has led to the hypothesis that seizures are caused by large-scale coordinated networks spanning these areas. This view, however, is difficult to reconcile with most proposed mechanisms of seizure ...

Last Updated: 29 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Seizures" returned 285 free, full-text review articles on human participants. First 3 results:

Bilateral posterior fracture-dislocation of the shoulders following epileptic seizures: a case report and review of the literature.
 

Author(s): Jagath Pushpakumara, Sivagamaroobasunthari Sivathiran, Lasantha Roshan, Saman Gunatilake

Journal:

 

Bilateral posterior fracture-dislocation of the shoulders is an uncommon complication of grand mal seizures. We report a case of bilateral posterior dislocation of the shoulders with proximal humeral fractures following epileptic seizures. A posterior fracture-dislocation of the shoulder ...

Last Updated: 24 Nov 2015

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Tranexamic acid-associated seizures: Causes and treatment.
 

Author(s): Irene Lecker, Dian-Shi Wang, Paul D Whissell, Sinziana Avramescu, C David Mazer, Beverley A Orser

Journal: Ann. Neurol.. 2016 Jan;79(1):18-26.

 

Antifibrinolytic drugs are routinely used worldwide to reduce the bleeding that results from a wide range of hemorrhagic conditions. The most commonly used antifibrinolytic drug, tranexamic acid, is associated with an increased incidence of postoperative seizures. The reported increase ...

Last Updated: 2 Feb 2016

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Brivaracetam: review of its pharmacology and potential use as adjunctive therapy in patients with partial onset seizures.
 

Author(s): Laura Mumoli, Caterina Palleria, Sara Gasparini, Rita Citraro, Angelo Labate, Edoardo Ferlazzo, Antonio Gambardella, Giovambattista De Sarro, Emilio Russo

Journal:

 

Brivaracetam (BRV), a high-affinity synaptic vesicle protein 2A ligand, reported to be 10-30-fold more potent than levetiracetam (LEV), is highly effective in a wide range of experimental models of focal and generalized seizures. BRV and LEV similarly bind to synaptic vesicle protein ...

Last Updated: 6 Nov 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Remegal Fixed Dose as Adjunctive Therapy in Patients With Partial Seizures
 

Status: Recruiting

Condition Summary: Epilepsy; Simple Partial Seizures; Complex Partial Seizures; Partial Seizures With Secondary Generalization

 

Last Updated: 11 Dec 2012

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Respiratory Physiology in Children With Febrile Seizures.
 

Status: Recruiting

Condition Summary: Febrile Illness in Children; Seizures, Febrile

 

Last Updated: 23 Jul 2013

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