Scott syndrome

Common Name(s)

Scott syndrome

Scott syndrome is a mild platelet-type bleeding disorder characterized by impaired surface exposure of procoagulant phosphatidylserine (PS) on platelets and other blood cells, following activation with Ca(2+)-elevating agents ({9:Munnix et al., 2003}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Scott syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Scott syndrome" returned 20 free, full-text research articles on human participants. First 3 results:

Mania with Aarskog-Scott syndrome.
 

Author(s): Raghavendra B Nayak, L Ambika, G S Bhogale, A Pandurangi

Journal: Indian Pediatr. 2012 Apr;49(4):327-8.

 

Aarskog-Scott syndrome is transmitted as an X-linked trait and affects males. We report a 10-year-old boy presenting with complaints of increased temper tantrums, demanding behavior, grandiose ideas, over familiarity, abusive assaultive behavior and tobacco abuse. On examination, ...

Last Updated: 8 May 2012

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Clinical utility gene card for: Aarskog-Scott syndrome (faciogenital dysplasia).
 

Author(s): Alfredo Orrico, Lucia Galli, Jill Clayton-Smith, Jean-Pierre Fryns

Journal: Eur. J. Hum. Genet.. 2011 Nov;19(11):.

 

Last Updated: 20 Oct 2011

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Compound heterozygosity for 2 novel TMEM16F mutations in a patient with Scott syndrome.
 

Author(s): Elisabetta Castoldi, Peter W Collins, Patrick L Williamson, Edouard M Bevers

Journal: Blood. 2011 Apr;117(16):4399-400.

 

Last Updated: 22 Apr 2011

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Scott syndrome" returned 1 free, full-text review articles on human participants. First 3 results:

Scott syndrome, a bleeding disorder caused by defective scrambling of membrane phospholipids.
 

Author(s): Robert F A Zwaal, Paul Comfurius, Edouard M Bevers

Journal: Biochim. Biophys. Acta. 2004 Mar;1636(2-3):119-28.

 

Normal quescent cells maintain membrane lipid asymmetry by ATP-dependent membrane lipid transporters, which shuttle different phospholipids from one leaflet to the other against their respective concentration gradients. When cells are challenged, membrane lipid asymmetry can be perturbed ...

Last Updated: 28 May 2004

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Markers of Defective Membrane Remodelling in Scott-like Syndromes
 

Status: Recruiting

Condition Summary: Unexplained Isolated Provoked Hemorrhages; Familial Bleeding Disorder; Scott Syndrome

 

Last Updated: 4 Sep 2014

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