Schwannoma

Common Name(s)

Schwannoma

Schwannomas are tumors of the tissue that covers the nerves (nerve sheath). These tumors develop from a type of cell called a Schwann cell, which gives them their name. They are usually benign (not cancerous). Although schwannomas can arise from any nerve in the body, the most common areas include the nerves of the head and neck and those involved with flexing in the arms and legs. Common symptoms include a slow-growing mass and Tinel shock (an electric-like shock when the affected area is touched). The cause of schwannomas is unknown, but they sometimes occur in people with certain disorders including some types of neurofibromatosis. Benign schwannomas are typically treated with surgery.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schwannoma" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Schwannoma" returned 668 free, full-text research articles on human participants. First 3 results:

Global Proteome and Phospho-proteome Analysis of Merlin-deficient Meningioma and Schwannoma Identifies PDLIM2 as a Novel Therapeutic Target.
 

Author(s): Kayleigh Bassiri, Sara Ferluga, Vikram Sharma, Nelofer Syed, Claire L Adams, Edwin Lasonder, C Oliver Hanemann

Journal: EBioMedicine. 2017 Feb;16():76-86.

 

Loss or mutation of the tumour suppressor Merlin predisposes individuals to develop multiple nervous system tumours, including schwannomas and meningiomas, sporadically or as part of the autosomal dominant inherited condition Neurofibromatosis 2 (NF2). These tumours display largely ...

Last Updated: 27 Jan 2017

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Vertigo Perception and Quality of Life in Patients after Surgical Treatment of Vestibular Schwannoma with Pretreatment Prehabituation by Chemical Vestibular Ablation.
 

Author(s): Zdeněk Čada, Zuzana Balatková, Martin Chovanec, Ondřej Čakrt, Silvie Hrubá, Jaroslav Jeřábek, Eduard Zvěřina, Oliver Profant, Zdeněk Fík, Martin Komarc, Jan Betka, Jan Kluh, Rudolf Černý

Journal: Biomed Res Int. 2016 ;2016():6767216.

 

Surgical removal of vestibular schwannoma causes acute vestibular symptoms, including postoperative vertigo and oscillopsia due to nystagmus. In general, the dominant symptom postoperatively is vertigo. Preoperative chemical vestibular ablation can reduce vestibular symptoms postoperatively. ...

Last Updated: 5 Jan 2017

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Clinical Neuropathology image 1-2017: incidental schwannoma of the posterior root.
 

Author(s): Ellen Gelpi, Mikel Vicente-Pascual

Journal: Clin. Neuropathol.. 2017 Jan;36 (2017)(1):3-4.

 

Last Updated: 14 Dec 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Schwannoma" returned 101 free, full-text review articles on human participants. First 3 results:

Epithelioid schwannoma of the skin displaying unique histopathological features: a teaching case giving rise to diagnostic difficulties on a morphological examination of a resected specimen, with a brief literature review.
 

Author(s): Sohsuke Yamada, Mari Kirishima, Tsubasa Hiraki, Michiyo Higashi, Kazuhito Hatanaka, Akihide Tanimoto

Journal:

 

Epithelioid schwannoma as a rare variant poses a challenge to all pathologists, as this uncommon entity is extremely difficult to conclusively diagnose by morphological analyses on a resected sample alone owing to its unique histopathological features. However, few papers have described ...

Last Updated: 20 Jan 2017

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Schwannoma of the biliary tract resembling cholangiocarcinoma: A case report and review.
 

Author(s): C Marin Campos, I Garcia Sanz, J L Muñoz de Nova, A Valdés de Anca, M E Martín Pérez

Journal: Ann R Coll Surg Engl. 2016 Sep;98(7):e143-6.

 

Schwannomas are benign tumours derived from Schwann cells and are extremely rare in the biliary tract. We present the case of a 62-year-old patient with a common bile duct schwannoma that resembled a cholangiocarcinoma. We also review all 17 previously published cases of schwannoma ...

Last Updated: 1 Sep 2016

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Schwannoma in Sellar Region Mimics Invasive Pituitary Macroadenoma: Literature Review With One Case Report.
 

Author(s): Xiangyi Kong, Huanwen Wu, Wenbin Ma, Yongning Li, Yi Yang, Bing Xing, Junji Wei, Yong Yao, Jun Gao, Wei Lian, Zhiqin Xu, Wanchen Dou, Zuyuan Ren, Changbao Su, Renzhi Wang

Journal: Medicine (Baltimore). 2016 Mar;95(9):e2931.

 

In central nervous system, schwannomas, as ubiquitous tumors, mostly originate from sensory nerves like auditory and trigeminal nerves. However, intrasellar schwannomas are extremely rare. They are often misdiagnosed as pituitary adenomas. We report a rare case of schwannoma in the ...

Last Updated: 6 Mar 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Vestibular Schwannoma - Radiosurgery or Expectation: V-REX.
 

Status: Recruiting

Condition Summary: Vestibular Schwannoma

 

Last Updated: 29 Feb 2016

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Gentamicin Treatment Prior to Schwannoma Surgery - Residual Function
 

Status: Recruiting

Condition Summary: Vestibular Schwannoma

 

Last Updated: 6 Sep 2016

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