Schizophrenia

Common Name(s)

Schizophrenia

Schizophrenia is a psychosis, a disorder of thought and sense of self. Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. There is no characteristic pathology, such as neurofibrillary tangles in Alzheimer disease ({104300}). Schizophrenia is a common disorder with a lifetime prevalence of approximately 1%. It is highly heritable but the genetics are complex. This may not be a single entity. Reviews In a review of schizophrenia, {167:van Os and Kapur (2009)} noted that in Japan the term schizophrenia was abandoned and the illness is now called integration-dysregulation syndrome.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 27 Apr 2015

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 6 Apr 2015

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Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

Last Updated: 22 Apr 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 27 Apr 2015

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 6 Apr 2015

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Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

http://www.simonsvipconnect.org

Last Updated: 22 Apr 2015

View Details

 

General Support Organizations

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General Resources

Schizophrenia

A brochure for individuals and families discussing symptoms, causes, treatment and recovery supports.

Updated 29 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Schizophrenia" returned 5823 free, full-text research articles on human participants. First 3 results:

Lumpers, splitters, and statistics: bipolar disorder, schizophrenia, and their relationship to seasonality.
 

Author(s): Fernando S Goes, J Raymond DePaulo

Journal: J Clin Psychiatry. 2015 Feb;76(2):e214-5.

 

Last Updated: 6 Mar 2015

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Prescription practices in the treatment of first-episode schizophrenia spectrum disorders: data from the national RAISE-ETP study.
 

Author(s): Delbert G Robinson, Nina R Schooler, Majnu John, Christoph U Correll, Patricia Marcy, Jean Addington, Mary F Brunette, Sue E Estroff, Kim T Mueser, David Penn, James Robinson, Robert A Rosenheck, Joanne Severe, Amy Goldstein, Susan Azrin, Robert Heinssen, John M Kane

Journal: Am J Psychiatry. 2015 Mar;172(3):237-48.

 

Treatment guidelines suggest distinctive medication strategies for first-episode and multiepisode patients with schizophrenia. To assess the extent to which community clinicians adjust their usual treatment regimens for first-episode patients, the authors examined prescription patterns ...

Last Updated: 2 Mar 2015

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[The perception of authorship in schizophrenia - the analysis of activity patterns in autonarrations].
 

Author(s): Małgorzata Chądzynska, Anna Osuchowska-Kościjańska, Agata Bednarek

Journal: Psychiatr. Pol.. ;48(6):1225-35.

 

The paper presents the study of narrations of schizophrenic patients focused on the description of activities characteristics. The aim is to answer the question of how experiencing of psychotic crisis influences the perception of their authorship. Do the inherent characteristics of ...

Last Updated: 26 Feb 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Schizophrenia" returned 1246 free, full-text review articles on human participants. First 3 results:

[Cognitive rehabilitation for people living with schizophrenia - the newest interventions].
 

Author(s): Magdalena Linke, Marek Jarema

Journal: Psychiatr. Pol.. ;48(6):1179-88.

 

The article reviews the latest interventions in cognitive rehabilitation for patients with schizophrenia. Studies referring to cognitive rehabilitation for people with schizophrenia from the last three years, found in the PubMed database, are presented. The authors categorised cognitive ...

Last Updated: 26 Feb 2015

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Schizophrenia: overview and dopamine dysfunction.
 

Author(s): Anissa Abi-Dargham

Journal: J Clin Psychiatry. 2014 Nov;75(11):e31.

 

Schizophrenia is a chronic, often disabling illness that affects approximately 24 million people worldwide. Unfortunately, while the majority of first-episode schizophrenia patients respond well to initial antipsychotic treatment, less than 1 in 5 will maintain recovery over 2 to ...

Last Updated: 4 Dec 2014

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Bridging the efficacy-effectiveness gap in the antipsychotic treatment of schizophrenia: back to the basics.
 

Author(s): Rajiv Tandon

Journal: J Clin Psychiatry. 2014 Nov;75(11):e1321-2.

 

Last Updated: 4 Dec 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluation of Efficacy and Safety of Long-acting Risperidone Microspheres in Patients With Schizophrenia or Other Psychotic Disorders When Switching From Typical Antipsychotic (Oral/Depot) or Atypical Oral Other Than Risperidone
 

Status: Recruiting

Condition Summary: Schizophrenia, Catatonic; Schizophrenia, Disorganized; Schizophrenia, Paranoid; Schizophrenia; Psychotic Disorders

 

Last Updated: 6 Jul 2010

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RISE (Rehabilitation Intervention for People With Schizophrenia in Ethiopia)
 

Status: Not yet recruiting

Condition Summary: Schizophrenia Spectrum Disorder; Schizophrenia; Schizoaffective Disorder; Schizophreniform Disorder

 

Last Updated: 31 Mar 2015

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Electroconvulsive Therapy (ECT) in Patients With Super Refractory Schizophrenia
 

Status: Recruiting

Condition Summary: Refractory Schizophrenia; Super Refractory Schizophrenia

 

Last Updated: 27 Jan 2014

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