Schizophrenia

Common Name(s)

Schizophrenia

Schizophrenia is a mental illness which affects social behavior and the ability to determine what is real. It is a lifelong, serious illness. Schizophrenia affects people of all genders, races, social classes and cultures. In total, the condition affects about 51 million people worldwide. Types include paranoid, disorganized, catatonic, residual, and schizoaffective.

Symptoms may include delusions, hallucinations, disorganized speech and behavior, and negative symptoms such as social withdrawal, poor hygiene and lack of inhibition. Symptoms often begin between the ages of 16 and 25 and may occur earlier in males. Schizophrenia may also cause problems with memory, attention and socialization.

The causes of schizophrenia are poorly understood but are believed to be caused by both genetics and the environment. Several genes when damaged are known to increase the risk of developing schizophrenia, but more are expected to be found. Other risk factors include exposure to malnutrition or viral infections before birth; heavy, frequent use of marijuana by teens and young adults; and problems with certain brain chemicals or neurotransmitters (dopamine and glutamate). Other factors which affect brain development may also be involved.

Diagnosis is made by examining the symptoms and ruling out other possible causes. Treatment includes antipsychotic medication and medications to help treat anxiety and depression. Group therapy may also be helpful. Treatment is lifelong, but it is often difficult to keep someone with schizophrenia on medications. Self-medication with street drugs is common. Suicide is a real concern. If you or a family member has been diagnosed with schizophrenia, talk to your psychiatrist, psychologist or therapist about the most current treatment options. A genetic counselor can help explain risks to other family members. Support groups are also good resources and can connect you with others affected by schizophrenia.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 6 Apr 2015

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Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

Last Updated: 20 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

View Details
National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 6 Apr 2015

View Details
Logo
Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

http://www.simonsvipconnect.org

Last Updated: 20 Jul 2015

View Details

 

General Support Organizations

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General Resources

Schizophrenia

A brochure for individuals and families discussing symptoms, causes, treatment and recovery supports.

Updated 29 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Schizophrenia" returned 7717 free, full-text research articles on human participants. First 3 results:

Influence of an inconsistent appearance of antipsychotics on drug adherence in patients with schizophrenia.
 

Author(s): Unax Lertxundi, Rafael Hernandez, Beatriz Corcóstegui, Olatz Ibarra, Gorka Mentxaka, Juan Medrano

Journal: Medicine (Baltimore). 2018 Nov;97(44):e12990.

 

In this study, we aimed to determine whether an inconsistent appearance of antipsychotic drugs dispensed was associated with poorer adherence in patients with schizophrenia.To conduct this study, we linked information from different administrative healthcare databases from the Basque ...

Last Updated: 31 Dec 1969

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Living the intensive order: Common sense and schizophrenia in Deleuze and Guattari.
 

Author(s): Julie Van der Wielen

Journal: Nurs Philos. 2018 Oct;19(4):e12226.

 

In Anti-Oedipus, Deleuze and Guattari aim to describe schizophrenia in a positive manner. According to them, the schizophrenic lives on the intensive order. To fully comprehend what this means, it is key to address some of Deleuze's insights regarding the notion of intensity in relation ...

Last Updated: 31 Dec 1969

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Characterization of neurological soft signs in a Brazilian sample of stable patients with schizophrenia.
 

Author(s): Vinicius Sousa Pietra Pedroso, Antônio Lúcio Teixeira, João Vinícius Salgado

Journal: Trends Psychiatry Psychother. ;40(3):244-247.

 

Neurological soft signs (NSS) have been considered one of the target features and a potential endophenotype for schizophrenia. The present study aimed to characterize NSS in a sample of patients with chronic schizophrenia and to compare them with healthy control individuals.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Schizophrenia" returned 1525 free, full-text review articles on human participants. First 3 results:

The difficulties of secondary prophylaxis of cervical cancer in women suffering from paranoid schizophrenia - a case study.
 

Author(s): Aneta Tylec, Halina Dubas-Ślemp, Anna Wójcicka, Bartłomiej Drop, Katarzyna Kucharska

Journal: Psychiatr. Pol.. 2018 Apr;52(2):251-259.

 

Cervical cancer constitutes 5.32% of all malignant neoplasm cases, it is the sixth most common condition of the cancer type and it is an important problem because of its medical, epidemiological and social implications. The aim of primary prophylaxis is to reduce the number of new ...

Last Updated: 31 Dec 1969

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Schizophrenia as a disorder of embodied self.
 

Author(s): Joanna Szczotka, Bartosz Majchrowicz

Journal: Psychiatr. Pol.. 2018 Apr;52(2):199-215.

 

Theories of schizophrenia propose numerous mechanisms underlying development of this disorder, yet the account including satisfactory etiological explanation is still lacking. Current trend is to indicate core, basic factors which may further give rise to whole diversity of symptoms. ...

Last Updated: 31 Dec 1969

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Clinical picture, pathogenesis and psychometric assessment of negative symptoms of schizophrenia.
 

Author(s): Paweł Wójciak, Janusz Rybakowski

Journal: Psychiatr. Pol.. 2018 Apr;52(2):185-197.

 

Negative symptoms of schizophrenia constitute a serious diagnostic and therapeutic problem. They substantially account for the impairment of health, social functioning and quality of life whereas treatment is difficult. In this paper the development of the concept of schizophrenia ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study to Assess Safety and Efficacy of KarXT in Adult Patients With Schizophrenia
 

Status: Recruiting

Condition Summary: Schizophrenia

 

Last Updated: 19 Oct 2018

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Last Updated: 5 Nov 2018

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The Optimal Treatment for Treatment-resistant Schizophrenia
 

Status: Recruiting

Condition Summary: Schizophrenia

 

Last Updated: 22 Feb 2018

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