Schizophrenia

Common Name(s)

Schizophrenia

Schizophrenia is a psychosis, a disorder of thought and sense of self. Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. There is no characteristic pathology, such as neurofibrillary tangles in Alzheimer disease ({104300}). Schizophrenia is a common disorder with a lifetime prevalence of approximately 1%. It is highly heritable but the genetics are complex. This may not be a single entity. Reviews In a review of schizophrenia, {167:van Os and Kapur (2009)} noted that in Japan the term schizophrenia was abandoned and the illness is now called integration-dysregulation syndrome.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 3 Oct 2013

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 29 Jan 2013

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General Support Organizations

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How do you compare to others with this condition?

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Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 3 Oct 2013

View Details
National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 29 Jan 2013

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General Support Organizations

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General Resources

Schizophrenia

A brochure for individuals and families discussing symptoms, causes, treatment and recovery supports.

Updated 29 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Schizophrenia" returned 5368 free, full-text research articles on human participants. First 3 results:

Managed care considerations. Optimal pharmacotherapy of schizophrenia.
 

Author(s): Roger Muller

Journal: Manag Care. 2014 Apr;23(4 Suppl 1):4.

 

Last Updated: 17 Jul 2014

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Delaying time to relapse in schizophrenia. The role of long-acting injectable antipsychotics.
 

Author(s): Roger Muller

Journal: Manag Care. 2014 Apr;23(4 Suppl 1):2-3.

 

Last Updated: 17 Jul 2014

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Methamphetamine enhances the development of schizophrenia in first-degree relatives of patients with schizophrenia.
 

Author(s): Huabing Li, Qiong Lu, Enhua Xiao, Qiuyun Li, Zhong He, Xilong Mei

Journal: Can J Psychiatry. 2014 Feb;59(2):107-13.

 

Although there is some evidence that methamphetamine (MA) abuse may play a causative role in the development of schizophrenia, studies directly linking these 2 are rare.

Last Updated: 2 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Schizophrenia" returned 1145 free, full-text review articles on human participants. First 3 results:

Understanding noise stress-induced cognitive impairment in healthy adults and its implications for schizophrenia.
 

Author(s): Bernice Wright, Emmanuelle Peters, Ulrich Ettinger, Elizabeth Kuipers, Veena Kumari

Journal: Noise Health. ;16(70):166-76.

 

Noise stress (NS) is detrimental to many aspects of human health and behavior. Understanding the effect of noise stressors on human cognitive function is a growing area of research and is crucial to helping clinical populations, such as those with schizophrenia, which are particularly ...

Last Updated: 23 Jun 2014

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Schizophrenia: mechanism of action of current and novel treatments.
 

Author(s): Christoph U Correll, John M Kane

Journal: J Clin Psychiatry. 2014 Apr;75(4):347-8.

 

Last Updated: 12 May 2014

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Neurocognitive vulnerability: suicidal and homicidal behaviours in patients with schizophrenia.
 

Author(s): St├ęphane Richard-Devantoy, Manuel Orsat, Alexandre Dumais, Gustavo Turecki, Fabrice Jollant

Journal: Can J Psychiatry. 2014 Jan;59(1):18-25.

 

Schizophrenia is associated with an increase in the risk of both homicide and suicide. The objectives of this study were to systematically review all published articles that examined the relation between neurocognitive deficits and suicidal or homicidal behaviours in schizophrenia, ...

Last Updated: 21 Jan 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluation of Efficacy and Safety of Long-acting Risperidone Microspheres in Patients With Schizophrenia or Other Psychotic Disorders When Switching From Typical Antipsychotic (Oral/Depot) or Atypical Oral Other Than Risperidone
 

Status: Recruiting

Condition Summary: Schizophrenia, Catatonic; Schizophrenia, Disorganized; Schizophrenia, Paranoid; Schizophrenia; Psychotic Disorders

 

Last Updated: 6 Jul 2010

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Peony-Glycyrrhiza Decoction (PGD) for Antipsychotic-induced Hyperprolactinemia in Patients With Schizophrenia
 

Status: Recruiting

Condition Summary: Schizophrenia; Schizophrenic Disorder; Hyperprolactinemia; Hyperprolactinaemia

 

Last Updated: 10 May 2013

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Yoga as Cognitive Remediation in Schizophrenia
 

Status: Recruiting

Condition Summary: Cognition in Schizophrenia; Independent Living Skills in Schizophrenia; Symptoms of Schizophrenia

 

Last Updated: 18 Jun 2013

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