Schizophrenia

Common Name(s)

Schizophrenia

Schizophrenia is a psychosis, a disorder of thought and sense of self. Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. There is no characteristic pathology, such as neurofibrillary tangles in Alzheimer disease ({104300}). Schizophrenia is a common disorder with a lifetime prevalence of approximately 1%. It is highly heritable but the genetics are complex. This may not be a single entity. Reviews In a review of schizophrenia, {167:van Os and Kapur (2009)} noted that in Japan the term schizophrenia was abandoned and the illness is now called integration-dysregulation syndrome.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 3 Oct 2013

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 29 Jan 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 3 Oct 2013

View Details
National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 29 Jan 2013

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General Support Organizations

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General Resources

Schizophrenia

A brochure for individuals and families discussing symptoms, causes, treatment and recovery supports.

Updated 29 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Schizophrenia" returned 5505 free, full-text research articles on human participants. First 3 results:

The use of electroconvulsive therapy and general anaesthesia in catatonic schizophrenia complicated by clozapine - induced pancytopenia - case report.
 

Author(s): Nikolina Jovanović, Vanja Lovretić, Martina Rojnić Kuzman

Journal: Psychiatr Danub. 2014 Sep;26(3):285-7.

 

Last Updated: 6 Sep 2014

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Influence of psycho-social factors on the emergence of depression and suicidal risk in patients with schizophrenia.
 

Author(s): Katarina Dokić Pješčić, Milutin M Nenadović, Miroslava Jašović-Gašić, Goran Trajković, Mirjana Kostić, Radmila Ristić-Dimitrijević

Journal: Psychiatr Danub. 2014 Sep;26(3):226-30.

 

The aim of this study was to investigate the influence of certain psychosocial factors - insight, psycho-education, family and social support, loneliness and social isolation - on the appearance of depression and suicidal risk in schizophrenia.

Last Updated: 6 Sep 2014

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Elevated neutrophil/lymphocyte ratio in patients with schizophrenia.
 

Author(s): Murat Semiz, Osman Yildirim, Fatih Canan, Suleyman Demir, Ekrem Hasbek, Taha Can Tuman, Nefise Kayka, Mehmet Tosun

Journal: Psychiatr Danub. 2014 Sep;26(3):220-5.

 

Inflammatory mechanisms are reported to play important roles in the pathophysiology of schizophrenia. The neutrophil-lymphocyte ratio (NLR) is a simple and easily accessible indicator of the systemic inflammatory response. Our goal was to investigate whether NLR was higher in patients ...

Last Updated: 6 Sep 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Schizophrenia" returned 1177 free, full-text review articles on human participants. First 3 results:

Understanding noise stress-induced cognitive impairment in healthy adults and its implications for schizophrenia.
 

Author(s): Bernice Wright, Emmanuelle Peters, Ulrich Ettinger, Elizabeth Kuipers, Veena Kumari

Journal: Noise Health. ;16(70):166-76.

 

Noise stress (NS) is detrimental to many aspects of human health and behavior. Understanding the effect of noise stressors on human cognitive function is a growing area of research and is crucial to helping clinical populations, such as those with schizophrenia, which are particularly ...

Last Updated: 23 Jun 2014

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Schizophrenia: mechanism of action of current and novel treatments.
 

Author(s): Christoph U Correll, John M Kane

Journal: J Clin Psychiatry. 2014 Apr;75(4):347-8.

 

Last Updated: 12 May 2014

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[The schizophrenia spectrum and other psychotic disorders in the DSM-5].
 

Author(s): N Tan, J van Os

Journal: Tijdschr Psychiatr. 2014 ;56(3):167-72.

 

This article discusses changes made in the diagnostic criteria for psychotic disorders in the transition from DSM-IV to DSM-5.

Last Updated: 19 Mar 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluation of Efficacy and Safety of Long-acting Risperidone Microspheres in Patients With Schizophrenia or Other Psychotic Disorders When Switching From Typical Antipsychotic (Oral/Depot) or Atypical Oral Other Than Risperidone
 

Status: Recruiting

Condition Summary: Schizophrenia, Catatonic; Schizophrenia, Disorganized; Schizophrenia, Paranoid; Schizophrenia; Psychotic Disorders

 

Last Updated: 6 Jul 2010

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Peony-Glycyrrhiza Decoction (PGD) for Antipsychotic-induced Hyperprolactinemia in Patients With Schizophrenia
 

Status: Recruiting

Condition Summary: Schizophrenia; Schizophrenic Disorder; Hyperprolactinemia; Hyperprolactinaemia

 

Last Updated: 10 May 2013

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RISE (Rehabilitation Intervention for People With Schizophrenia in Ethiopia)
 

Status: Not yet recruiting

Condition Summary: Schizophrenia Spectrum Disorder; Schizophrenia; Schizoaffective Disorder; Schizophreniform Disorder

 

Last Updated: 9 Jun 2014

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