Schizophrenia

Common Name(s)

Schizophrenia

Schizophrenia is a psychosis, a disorder of thought and sense of self. Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. There is no characteristic pathology, such as neurofibrillary tangles in Alzheimer disease ({104300}). Schizophrenia is a common disorder with a lifetime prevalence of approximately 1%. It is highly heritable but the genetics are complex. This may not be a single entity. Reviews In a review of schizophrenia, {167:van Os and Kapur (2009)} noted that in Japan the term schizophrenia was abandoned and the illness is now called integration-dysregulation syndrome.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 3 Oct 2013

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 29 Jan 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 3 Oct 2013

View Details
National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 29 Jan 2013

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General Support Organizations

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General Resources

Schizophrenia

A brochure for individuals and families discussing symptoms, causes, treatment and recovery supports.

Updated 29 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Schizophrenia" returned 5544 free, full-text research articles on human participants. First 3 results:

[Reaction on 'The stigmatising of schizophrenia and autism in the Flemish daily papers'].
 

Author(s): H Tjeerdema

Journal: Tijdschr Psychiatr. 2014 ;56(9):629-31.

 

Last Updated: 16 Sep 2014

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The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for gXe research.
 

Author(s): James B Kirkbride

Journal: Soc Psychiatry Psychiatr Epidemiol. 2014 Oct;49(10):1531-4.

 

In this commentary I review the recent paper by Iyegbe et al. on "The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for gXe research". I discuss how the paper advances our knowledge of polygenic risk scores for use, amongst others, ...

Last Updated: 17 Sep 2014

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The use of electroconvulsive therapy and general anaesthesia in catatonic schizophrenia complicated by clozapine - induced pancytopenia - case report.
 

Author(s): Nikolina Jovanović, Vanja Lovretić, Martina Rojnić Kuzman

Journal: Psychiatr Danub. 2014 Sep;26(3):285-7.

 

Last Updated: 6 Sep 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Schizophrenia" returned 1185 free, full-text review articles on human participants. First 3 results:

Understanding noise stress-induced cognitive impairment in healthy adults and its implications for schizophrenia.
 

Author(s): Bernice Wright, Emmanuelle Peters, Ulrich Ettinger, Elizabeth Kuipers, Veena Kumari

Journal: Noise Health. ;16(70):166-76.

 

Noise stress (NS) is detrimental to many aspects of human health and behavior. Understanding the effect of noise stressors on human cognitive function is a growing area of research and is crucial to helping clinical populations, such as those with schizophrenia, which are particularly ...

Last Updated: 23 Jun 2014

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[Minocycline for schizophrenia: a brief overview].
 

Author(s): J E Hovens, T A M Onderwater

Journal: Tijdschr Psychiatr. 2014 ;56(6):402-6.

 

The tetracyclic antibiotic minocycline appears to have positive results when added to the the treatment prescribed for persistent symptoms of schizophrenia.

Last Updated: 23 Jun 2014

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[Functional MRI for schizophrenia: importance of the type of task being scanned].
 

Author(s): J Van Hecke, T E Gladwin, J Coremans, W Hulstijn, B Sabbe

Journal: Tijdschr Psychiatr. 2014 ;56(6):385-93.

 

Functional magnetic resonance imaging (fMRI) is an important technique for detecting neural network problems in patients with schizophrenia. Very often, however, the professionals involved are insufficiently aware of the fact that when fMRI scans are used for patients with schizophrenia, ...

Last Updated: 23 Jun 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluation of Efficacy and Safety of Long-acting Risperidone Microspheres in Patients With Schizophrenia or Other Psychotic Disorders When Switching From Typical Antipsychotic (Oral/Depot) or Atypical Oral Other Than Risperidone
 

Status: Recruiting

Condition Summary: Schizophrenia, Catatonic; Schizophrenia, Disorganized; Schizophrenia, Paranoid; Schizophrenia; Psychotic Disorders

 

Last Updated: 6 Jul 2010

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RISE (Rehabilitation Intervention for People With Schizophrenia in Ethiopia)
 

Status: Not yet recruiting

Condition Summary: Schizophrenia Spectrum Disorder; Schizophrenia; Schizoaffective Disorder; Schizophreniform Disorder

 

Last Updated: 9 Jun 2014

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Electroconvulsive Therapy (ECT) in Patients With Super Refractory Schizophrenia
 

Status: Recruiting

Condition Summary: Refractory Schizophrenia; Super Refractory Schizophrenia

 

Last Updated: 27 Jan 2014

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