SARS

Common Name(s)

SARS

Severe Acute Respiratory Syndrome (SARS) is a respiratory illness belonging to a common class of viruses called coronaviruses. SARS was first reported in Asia in February 2003 and spread quickly to two dozen countries before being contained successfully. There have been no outbreaks since 2004. Symptoms usually begin with a high fever, and may include a headache, an overall feeling of discomfort, and body aches. Some people have mild respiratory symptoms at the outset, and 10-20% experience diarrhea. After 2-7 days, SARS patients may develop a dry cough. Most will develop pneumonia as a secondary infection. SARS is most easily spread by respiratory droplets released when an infected individual coughs or sneezes.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "SARS" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "SARS" returned 742 free, full-text research articles on human participants. First 3 results:

Network-based analysis of comorbidities risk during an infection: SARS and HIV case studies.
 

Author(s): Mohammad Ali Moni, Pietro Liò

Journal:

 

Infections are often associated to comorbidity that increases the risk of medical conditions which can lead to further morbidity and mortality. SARS is a threat which is similar to MERS virus, but the comorbidity is the key aspect to underline their different impacts. One UK doctor ...

Last Updated: 13 Jan 2015

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SARS-CoV envelope protein palmitoylation or nucleocapid association is not required for promoting virus-like particle production.
 

Author(s): Ying-Tzu Tseng, Shiu-Mei Wang, Kuo-Jung Huang, Chin-Tien Wang

Journal:

 

Coronavirus membrane (M) proteins are capable of interacting with nucleocapsid (N) and envelope (E) proteins. Severe acute respiratory syndrome coronavirus (SARS-CoV) M co-expression with either N or E is sufficient for producing virus-like particles (VLPs), although at a lower level ...

Last Updated: 3 Jun 2014

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The YXXΦ motif within the severe acute respiratory syndrome coronavirus (SARS-CoV) 3a protein is crucial for its intracellular transport.
 

Author(s): Rinki Minakshi, Kartika Padhan

Journal:

 

The SARS coronavirus (SARS-CoV) 3a protein functions as an ion channel, induces apoptosis and is important for viral pathogenesis. It is expressed on the cell surface and contains a tyrosine-based sorting motif and a di-acidic motif, which may be crucial for its intracellular trafficking. ...

Last Updated: 30 Apr 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "SARS" returned 70 free, full-text review articles on human participants. First 3 results:

Proteolytic activation of the SARS-coronavirus spike protein: cutting enzymes at the cutting edge of antiviral research.
 

Author(s): Graham Simmons, Pawel Zmora, Stefanie Gierer, Adeline Heurich, Stefan Pöhlmann

Journal: Antiviral Res.. 2013 Dec;100(3):605-14.

 

The severe acute respiratory syndrome (SARS) pandemic revealed that zoonotic transmission of animal coronaviruses (CoV) to humans poses a significant threat to public health and warrants surveillance and the development of countermeasures. The activity of host cell proteases, which ...

Last Updated: 25 Nov 2013

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Clinical management and infection control of SARS: lessons learned.
 

Author(s): Vincent C C Cheng, Jasper F W Chan, Kelvin K W To, K Y Yuen

Journal: Antiviral Res.. 2013 Nov;100(2):407-19.

 

The outbreak of severe acute respiratory syndrome (SARS) in 2003 was the first emergence of an important human pathogen in the 21st century. Responding to the epidemic provided clinicians with extensive experience in diagnosing and treating a novel respiratory viral disease. In this ...

Last Updated: 4 Nov 2013

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Receptor recognition and cross-species infections of SARS coronavirus.
 

Author(s): Fang Li

Journal: Antiviral Res.. 2013 Oct;100(1):246-54.

 

Receptor recognition is a major determinant of the host range, cross-species infections, and pathogenesis of the severe acute respiratory syndrome coronavirus (SARS-CoV). A defined receptor-binding domain (RBD) in the SARS-CoV spike protein specifically recognizes its host receptor, ...

Last Updated: 25 Nov 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Respiratory Virus Hospitalization Study (FLU 003 Plus)
 

Status: Recruiting

Condition Summary: Influenza; Novel Respiratory Virus-1 MERS-CoV; Novel Respiratory Virus-2 SARS-CoV

 

Last Updated: 17 Dec 2014

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SAR650984, Pomalidomide and Dexamethasone in Combination in RRMM Patients
 

Status: Recruiting

Condition Summary: Haematological Malignancy

 

Last Updated: 9 Apr 2015

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