SARS

Common Name(s)

SARS

Severe Acute Respiratory Syndrome (SARS) is a respiratory illness belonging to a common class of viruses called coronaviruses. SARS was first reported in Asia in February 2003 and spread quickly to two dozen countries before being contained successfully. There have been no outbreaks since 2004. Symptoms usually begin with a high fever, and may include a headache, an overall feeling of discomfort, and body aches. Some people have mild respiratory symptoms at the outset, and 10-20% experience diarrhea. After 2-7 days, SARS patients may develop a dry cough. Most will develop pneumonia as a secondary infection. SARS is most easily spread by respiratory droplets released when an infected individual coughs or sneezes.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "SARS" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "SARS" returned 824 free, full-text research articles on human participants. First 3 results:

Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus.
 

Author(s): Ben Hu, Lei-Ping Zeng, Xing-Lou Yang, Xing-Yi Ge, Wei Zhang, Bei Li, Jia-Zheng Xie, Xu-Rui Shen, Yun-Zhi Zhang, Ning Wang, Dong-Sheng Luo, Xiao-Shuang Zheng, Mei-Niang Wang, Peter Daszak, Lin-Fa Wang, Jie Cui, Zheng-Li Shi

Journal:

 

A large number of SARS-related coronaviruses (SARSr-CoV) have been detected in horseshoe bats since 2005 in different areas of China. However, these bat SARSr-CoVs show sequence differences from SARS coronavirus (SARS-CoV) in different genes (S, ORF8, ORF3, etc) and are considered ...

Last Updated: 31 Dec 1969

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A Novel Chemical Compound for Inhibition of SARS Coronavirus Helicase.
 

Author(s): Jin-Moo Lee, Jin-Beom Cho, Hee-Chul Ahn, Woong Jung, Yong-Joo Jeong

Journal: J. Microbiol. Biotechnol.. 2017 Nov;27(11):2070-2073.

 

We have discovered a novel chemical compound, (E)-3-(furan-2-yl)--(4-sulfamoylphenyl) acrylamide, that suppresses the enzymatic activities of SARS coronavirus helicase. To determine the inhibitory effect, ATP hydrolysis and double-stranded DNA unwinding assays were performed in the ...

Last Updated: 31 Dec 1969

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Role of fomites in SARS transmission during the largest hospital outbreak in Hong Kong.
 

Author(s): Shenglan Xiao, Yuguo Li, Tze-Wai Wong, David S C Hui

Journal:

 

The epidemic of severe acute respiratory syndrome (SARS) had a significant effect on global society in the early 2000s and the potential of its resurgence exists. Studies on the modes of transmission of SARS are limited though a number of outbreak studies have revealed the possible ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "SARS" returned 89 free, full-text review articles on human participants. First 3 results:

The role of epidermal growth factor receptor (EGFR) signaling in SARS coronavirus-induced pulmonary fibrosis.
 

Author(s): Thiagarajan Venkataraman, Matthew B Frieman

Journal: Antiviral Res.. 2017 07;143():142-150.

 

Many survivors of the 2003 outbreak of severe acute respiratory syndrome (SARS) developed residual pulmonary fibrosis with increased severity seen in older patients. Autopsies of patients that died from SARS also showed fibrosis to varying extents. Pulmonary fibrosis can be occasionally ...

Last Updated: 31 Dec 1969

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Pains and Gains from China's Experiences with Emerging Epidemics: From SARS to H7N9.
 

Author(s): Pengfei Wei, Zelang Cai, Jinwen Hua, Weijia Yu, Jiajie Chen, Kang Kang, Congling Qiu, Lanlan Ye, Jiayun Hu, Kunmei Ji

Journal: Biomed Res Int. 2016 ;2016():5717108.

 

Over the recent decades, China experienced several emerging virus outbreaks including those caused by the severe acute respiratory syndrome- (SARS-) coronavirus (Cov), H5N1 virus, and H7N9 virus. The SARS tragedy revealed faults in China's infectious disease prevention system, propelling ...

Last Updated: 31 Dec 1969

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Middle East respiratory syndrome: SARS redux?
 

Author(s): Glenn W Wortmann

Journal: Cleve Clin J Med. 2015 Sep;82(9):584-8.

 

Middle East respiratory syndrome (MERS) is caused by the Middle East respiratory syndrome coronavirus (MERS-CoV). Although predominantly affecting countries across the Arabian Peninsula, the infection has been exported by travelers to countries around the world, including the United ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Long-term Assessment of Organ Functions Among Survivors of Severe Acute Respiratory Syndrome
 

Status: Recruiting

Condition Summary: SARS Virus; Long-Term Survivors

 

Last Updated: 22 Feb 2018

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Last Updated: 21 Aug 2018

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Last Updated: 17 May 2018

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