SARS

Common Name(s)

SARS

Severe Acute Respiratory Syndrome (SARS) is a respiratory illness belonging to a common class of viruses called coronaviruses. SARS was first reported in Asia in February 2003 and spread quickly to two dozen countries before being contained successfully. There have been no outbreaks since 2004. Symptoms usually begin with a high fever, and may include a headache, an overall feeling of discomfort, and body aches. Some people have mild respiratory symptoms at the outset, and 10-20% experience diarrhea. After 2-7 days, SARS patients may develop a dry cough. Most will develop pneumonia as a secondary infection. SARS is most easily spread by respiratory droplets released when an infected individual coughs or sneezes.

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "SARS" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "SARS" returned 743 free, full-text research articles on human participants. First 3 results:

SARS-CoV envelope protein palmitoylation or nucleocapid association is not required for promoting virus-like particle production.
 

Author(s): Ying-Tzu Tseng, Shiu-Mei Wang, Kuo-Jung Huang, Chin-Tien Wang

Journal:

 

Coronavirus membrane (M) proteins are capable of interacting with nucleocapsid (N) and envelope (E) proteins. Severe acute respiratory syndrome coronavirus (SARS-CoV) M co-expression with either N or E is sufficient for producing virus-like particles (VLPs), although at a lower level ...

Last Updated: 3 Jun 2014

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The YXXΦ motif within the severe acute respiratory syndrome coronavirus (SARS-CoV) 3a protein is crucial for its intracellular transport.
 

Author(s): Rinki Minakshi, Kartika Padhan

Journal:

 

The SARS coronavirus (SARS-CoV) 3a protein functions as an ion channel, induces apoptosis and is important for viral pathogenesis. It is expressed on the cell surface and contains a tyrosine-based sorting motif and a di-acidic motif, which may be crucial for its intracellular trafficking. ...

Last Updated: 30 Apr 2014

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From SARS to H7N9: the mechanism of responding to emerging communicable diseases has made great progress in China.
 

Author(s): Linong Yao, Enfu Chen, Zhiping Chen, Zhenyu Gong

Journal: Biosci Trends. 2013 Dec;7(6):290-3.

 

The outbreak of severe acute respiratory syndrome (SARS) in 2003 indicated that China's existing former mechanism for emergency management was very vulnerable. The Chinese Government has since established a new mechanism for responding to emerging communicable diseases. This paper ...

Last Updated: 6 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "SARS" returned 69 free, full-text review articles on human participants. First 3 results:

Clinical management and infection control of SARS: lessons learned.
 

Author(s): Vincent C C Cheng, Jasper F W Chan, Kelvin K W To, K Y Yuen

Journal: Antiviral Res.. 2013 Nov;100(2):407-19.

 

The outbreak of severe acute respiratory syndrome (SARS) in 2003 was the first emergence of an important human pathogen in the 21st century. Responding to the epidemic provided clinicians with extensive experience in diagnosing and treating a novel respiratory viral disease. In this ...

Last Updated: 4 Nov 2013

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Receptor recognition and cross-species infections of SARS coronavirus.
 

Author(s): Fang Li

Journal: Antiviral Res.. 2013 Oct;100(1):246-54.

 

Receptor recognition is a major determinant of the host range, cross-species infections, and pathogenesis of the severe acute respiratory syndrome coronavirus (SARS-CoV). A defined receptor-binding domain (RBD) in the SARS-CoV spike protein specifically recognizes its host receptor, ...

Last Updated: 25 Nov 2013

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Therapeutic options for Middle East respiratory syndrome coronavirus (MERS-CoV)--possible lessons from a systematic review of SARS-CoV therapy.
 

Author(s): Hisham Momattin, Khurram Mohammed, Alimuddin Zumla, Ziad A Memish, Jaffar A Al-Tawfiq

Journal: Int. J. Infect. Dis.. 2013 Oct;17(10):e792-8.

 

The Middle East Respiratory Syndrome coronavirus (MERS-CoV) has been detected in a number of countries in the Middle East and Europe with an apparently high mortality rate. It is phylogenetically related to the SARS coronavirus and has also been associated with severe respiratory ...

Last Updated: 16 Sep 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

INSIGHT Respiratory Virus Hospitalization Study (FLU 003 Plus)
 

Status: Recruiting

Condition Summary: Influenza; Novel Respiratory Virus-1 MERS-CoV; Novel Respiratory Virus-2 SARS-CoV

 

Last Updated: 9 Oct 2014

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Trial of Pimasertib With SAR245409 or Placebo in Ovarian Cancer
 

Status: Recruiting

Condition Summary: Ovarian Cancer

 

Last Updated: 7 Jul 2014

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