SARS

Common Name(s)

SARS

Severe Acute Respiratory Syndrome (SARS) is a respiratory illness belonging to a common class of viruses called coronaviruses. SARS was first reported in Asia in February 2003 and spread quickly to two dozen countries before being contained successfully. There have been no outbreaks since 2004. Symptoms usually begin with a high fever, and may include a headache, an overall feeling of discomfort, and body aches. Some people have mild respiratory symptoms at the outset, and 10-20% experience diarrhea. After 2-7 days, SARS patients may develop a dry cough. Most will develop pneumonia as a secondary infection. SARS is most easily spread by respiratory droplets released when an infected individual coughs or sneezes.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "SARS" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "SARS" returned 749 free, full-text research articles on human participants. First 3 results:

10th anniversary of SARS: China is better prepared for the H7N9 avian influenza outbreak.
 

Author(s): Yi Zhang, Yong-Sheng Yu, Zheng-Hao Tang, Xiao-Hua Chen, Guo-Qing Zang

Journal:

 

Last Updated: 16 Oct 2013

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A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses.
 

Author(s): Hugh D Mitchell, Amie J Eisfeld, Amy C Sims, Jason E McDermott, Melissa M Matzke, Bobbi-Jo M Webb-Robertson, Susan C Tilton, Nicolas Tchitchek, Laurence Josset, Chengjun Li, Amy L Ellis, Jean H Chang, Robert A Heegel, Maria L Luna, Athena A Schepmoes, Anil K Shukla, Thomas O Metz, Gabriele Neumann, Arndt G Benecke, Richard D Smith, Ralph S Baric, Yoshihiro Kawaoka, Michael G Katze, Katrina M Waters

Journal:

 

Respiratory infections stemming from influenza viruses and the Severe Acute Respiratory Syndrome corona virus (SARS-CoV) represent a serious public health threat as emerging pandemics. Despite efforts to identify the critical interactions of these viruses with host machinery, the ...

Last Updated: 12 Aug 2013

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Synergistic inhibitor binding to the papain-like protease of human SARS coronavirus: mechanistic and inhibitor design implications.
 

Author(s): Hyun Lee, Shuyi Cao, Kirk E Hevener, Lena Truong, Joseph L Gatuz, Kavankumar Patel, Arun K Ghosh, Michael E Johnson

Journal: ChemMedChem. 2013 Aug;8(8):1361-72.

 

We previously developed two potent chemical classes that inhibit the essential papain-like protease (PLpro) of severe acute respiratory syndrome coronavirus. In this study, we applied a novel approach to identify small fragments that act synergistically with these inhibitors. A fragment ...

Last Updated: 29 Jul 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "SARS" returned 69 free, full-text review articles on human participants. First 3 results:

Clinical management and infection control of SARS: lessons learned.
 

Author(s): Vincent C C Cheng, Jasper F W Chan, Kelvin K W To, K Y Yuen

Journal: Antiviral Res.. 2013 Nov;100(2):407-19.

 

The outbreak of severe acute respiratory syndrome (SARS) in 2003 was the first emergence of an important human pathogen in the 21st century. Responding to the epidemic provided clinicians with extensive experience in diagnosing and treating a novel respiratory viral disease. In this ...

Last Updated: 4 Nov 2013

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Therapeutic options for Middle East respiratory syndrome coronavirus (MERS-CoV)--possible lessons from a systematic review of SARS-CoV therapy.
 

Author(s): Hisham Momattin, Khurram Mohammed, Alimuddin Zumla, Ziad A Memish, Jaffar A Al-Tawfiq

Journal: Int. J. Infect. Dis.. 2013 Oct;17(10):e792-8.

 

The Middle East Respiratory Syndrome coronavirus (MERS-CoV) has been detected in a number of countries in the Middle East and Europe with an apparently high mortality rate. It is phylogenetically related to the SARS coronavirus and has also been associated with severe respiratory ...

Last Updated: 16 Sep 2013

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Viral pathogens and acute lung injury: investigations inspired by the SARS epidemic and the 2009 H1N1 influenza pandemic.
 

Author(s): Carolyn M Hendrickson, Michael A Matthay

Journal: Semin Respir Crit Care Med. 2013 Aug;34(4):475-86.

 

Acute viral pneumonia is an important cause of acute lung injury (ALI), although not enough is known about the exact incidence of viral infection in ALI. Polymerase chain reaction-based assays, direct fluorescent antigen (DFA) assays, and viral cultures can detect viruses in samples ...

Last Updated: 12 Aug 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Induction of Cytokines in Human Monocytes by SARS-CoV in Adults and Children
 

Status: Recruiting

Condition Summary: Healthy

 

Last Updated: 30 Nov 2007

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