Sarcoidosis

Common Name(s)

Sarcoidosis

Sarcoidosis is an inflammatory disease characterized by the development and growth of tiny lumps of cells called granulomas. If these tiny granulomas grow and clump together in an organ, they can affect how the organ works, leading to the symptoms of sarcoidosis. The granulomas can be found in almost any part of the body, but occur more commonly in the lungs, lymph nodes, eyes, skin, and liver.  Although no one is sure what causes sarcoidosis, it is thought by most scientists to be a disorder of the immune system.  The course of the disease varies from person to person. It often goes away on its own, but in some people symptoms of sarcoidosis may last a lifetime. For those who need treatment, anti-inflammatory medications can help.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sarcoidosis" for support, advocacy or research.

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Foundation for Sarcoidosis Research

The Foundation for Sarcoidosis Research is the nation's leading nonprofit organization dedicated to finding a cure for this disease and to improving care for sarcoidosis patients. Since its establishment in 2000, FSR has funded numerous domestic and international research efforts and worked diligently to provide resources to thousands.

Last Updated: 19 Feb 2013

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Janine's sarcoidosis outreach foundation

Our mission is to empower communities through Sarcoidosis Education and Outreach

Last Updated: 19 Feb 2013

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Sarcoid Networking Association

The Sarcoid Networking Association was founded in 1992 to educate individuals, provide information and heighten public awareness about sarcoidosis.

Last Updated: 30 Apr 2014

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Sarcoidosis Australia

Bring fellow sufferers together to support each other and their families Provide and share information and experiences, acting as a forum to help those affected to understand the condition Support the medical profession in the early diagnosis and treatment of those with these diseases Support the medical profession in research into the disease Heighten awareness of the disease in Australia

Last Updated: 2 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sarcoidosis" for support, advocacy or research.

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Foundation for Sarcoidosis Research

The Foundation for Sarcoidosis Research is the nation's leading nonprofit organization dedicated to finding a cure for this disease and to improving care for sarcoidosis patients. Since its establishment in 2000, FSR has funded numerous domestic and international research efforts and worked diligently to provide resources to thousands.

http://www.stopsarcoidosis.org

Last Updated: 19 Feb 2013

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Janine's sarcoidosis outreach foundation

Our mission is to empower communities through Sarcoidosis Education and Outreach

http://www.jsof.org

Last Updated: 19 Feb 2013

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Sarcoid Networking Association

The Sarcoid Networking Association was founded in 1992 to educate individuals, provide information and heighten public awareness about sarcoidosis.

http://www.sarcoidosisnetwork.org

Last Updated: 30 Apr 2014

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Sarcoidosis Australia

Bring fellow sufferers together to support each other and their families Provide and share information and experiences, acting as a forum to help those affected to understand the condition Support the medical profession in the early diagnosis and treatment of those with these diseases Support the medical profession in research into the disease Heighten awareness of the disease in Australia

http://www.sarcoidosisaustralia.com

Last Updated: 2 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Sarcoidosis" returned 1956 free, full-text research articles on human participants. First 3 results:

An atypical sarcoidosis involvement in FDG PET/CT: A case report.
 

Author(s): Philippe Robin, Paolo Benigni, Benoit Feger, Pierre-Yves Salaun, Ronan Abgral

Journal: Medicine (Baltimore). 2016 Dec;95(52):e5700.

 

Sarcoidosis is an idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis which involve various organs. Laryngeal involvement is extremely rare, with a prevalence of about 0.5 to 1%.

Last Updated: 29 Dec 2016

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Vitreous lavage fluid and bronchoalveolar lavage fluid have equal diagnostic value in sarcoidosis.
 

Author(s): Kazuichi Maruyama, Tohru Inaba, Tsutomu Tamada, Toru Nakazawa

Journal: Medicine (Baltimore). 2016 Dec;95(49):e5531.

 

Here, we elucidate the immunological features of both bronchoalveolar lavage fluid (BALF) and vitreous lavage fluid (VLF) samples from patients with histopathologically verified sarcoidosis. In addition, we assess the safety of vitrectomy in sarcoidosis patients by investigating the ...

Last Updated: 8 Dec 2016

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Differential Expression of Cardiac Troponin T and I in a Patient with Isolated Skeletal Muscular Sarcoidosis.
 

Author(s): Hiroshi Mannoji, Fumie Hayashi, Toru Kubota, Yoshihiko Ikeda, Hatsue Ishibashi-Ueda, Seiya Kato, Nobuhiro Tahara, Takayoshi Fukutomi, Takeshi Yamada, Masanori Okabe, Yusuke Yamamoto

Journal: Intern. Med.. ;55(21):3215-3217.

 

A 49-year-old female was referred to our hospital due to high serum creatine kinase (CK) (2,605 IU/L) and serum cardiac troponin T (cTnT) (0.342 ng/mL) levels. She had no other complaints and further examinations suggested no signs of cardiac disease. Additionally, the serum cardiac ...

Last Updated: 2 Nov 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Sarcoidosis" returned 190 free, full-text review articles on human participants. First 3 results:

Cryptococcal meningitis complicating sarcoidosis.
 

Author(s): Sonja E Leonhard, Daan Fritz, Diederik van de Beek, Matthijs C Brouwer

Journal: Medicine (Baltimore). 2016 Aug;95(35):e4587.

 

Cryptococcal meningitis is an uncommon but severe complication of sarcoidosis.

Last Updated: 2 Sep 2016

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Annexins family: insights into their functions and potential role in pathogenesis of sarcoidosis.
 

Author(s): Mehdi Mirsaeidi, Sanaz Gidfar, Ann Vu, Dean Schraufnagel

Journal:

 

Annexins are Ca(2+)-regulated phospholipid-binding proteins that play an important role in the cell life cycle, exocytosis, and apoptosis. Annexin A11 is one of the oldest vertebrate annexins that has a crucial role in sarcoidosis pathogenesis. The mechanism of effect in sarcoidosis ...

Last Updated: 13 Apr 2016

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Ocular Sarcoidosis.
 

Author(s): Sirichai Pasadhika, James T Rosenbaum

Journal: Clin. Chest Med.. 2015 Dec;36(4):669-83.

 

Sarcoidosis is one of the leading causes of inflammatory eye disease. Ocular sarcoidosis can involve any part of the eye and its adnexal tissues and may cause uveitis, episcleritis/scleritis, eyelid abnormalities, conjunctival granuloma, optic neuropathy, lacrimal gland enlargement, ...

Last Updated: 23 Nov 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Worldwide Sarcoidosis Research Study
 

Status: Recruiting

Condition Summary: Sarcoidosis

 

Last Updated: 27 May 2015

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Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis
 

Status: Recruiting

Condition Summary: Sarcoidosis

 

Last Updated: 24 Jan 2017

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Acthar Gel for Chronic Pulmonary Sarcoidosis (ACPS)
 

Status: Recruiting

Condition Summary: Sarcoidosis; Pulmonary Sarcoidosis

 

Last Updated: 4 Dec 2015

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