Sarcoidosis

Common Name(s)

Sarcoidosis

Sarcoidosis is an inflammatory disease characterized by the development and growth of tiny lumps of cells called granulomas. If these tiny granulomas grow and clump together in an organ, they can affect how the organ works, leading to the symptoms of sarcoidosis. The granulomas can be found in almost any part of the body, but occur more commonly in the lungs, lymph nodes, eyes, skin, and liver.  Although no one is sure what causes sarcoidosis, it is thought by most scientists to be a disorder of the immune system.  The course of the disease varies from person to person. It often goes away on its own, but in some people symptoms of sarcoidosis may last a lifetime. For those who need treatment, anti-inflammatory medications can help.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sarcoidosis" for support, advocacy or research.

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Foundation for Sarcoidosis Research

The Foundation for Sarcoidosis Research is the nation's leading nonprofit organization dedicated to finding a cure for this disease and to improving care for sarcoidosis patients. Since its establishment in 2000, FSR has funded numerous domestic and international research efforts and worked diligently to provide resources to thousands.

Last Updated: 19 Feb 2013

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Janine's sarcoidosis outreach foundation

Our mission is to empower communities through Sarcoidosis Education and Outreach

Last Updated: 19 Feb 2013

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Sarcoid Networking Association

The Sarcoid Networking Association was founded in 1992 to educate individuals, provide information and heighten public awareness about sarcoidosis.

Last Updated: 30 Apr 2014

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Sarcoidosis Australia

Bring fellow sufferers together to support each other and their families Provide and share information and experiences, acting as a forum to help those affected to understand the condition Support the medical profession in the early diagnosis and treatment of those with these diseases Support the medical profession in research into the disease Heighten awareness of the disease in Australia

Last Updated: 2 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sarcoidosis" for support, advocacy or research.

Logo
Foundation for Sarcoidosis Research

The Foundation for Sarcoidosis Research is the nation's leading nonprofit organization dedicated to finding a cure for this disease and to improving care for sarcoidosis patients. Since its establishment in 2000, FSR has funded numerous domestic and international research efforts and worked diligently to provide resources to thousands.

http://www.stopsarcoidosis.org

Last Updated: 19 Feb 2013

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Janine's sarcoidosis outreach foundation

Our mission is to empower communities through Sarcoidosis Education and Outreach

http://www.jsof.org

Last Updated: 19 Feb 2013

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Sarcoid Networking Association

The Sarcoid Networking Association was founded in 1992 to educate individuals, provide information and heighten public awareness about sarcoidosis.

http://www.sarcoidosisnetwork.org

Last Updated: 30 Apr 2014

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Sarcoidosis Australia

Bring fellow sufferers together to support each other and their families Provide and share information and experiences, acting as a forum to help those affected to understand the condition Support the medical profession in the early diagnosis and treatment of those with these diseases Support the medical profession in research into the disease Heighten awareness of the disease in Australia

http://www.sarcoidosisaustralia.com

Last Updated: 2 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Sarcoidosis" returned 1597 free, full-text research articles on human participants. First 3 results:

Disposal of iNKT cell deficiency and an increase in expression of SLAM signaling factors characterizes sarcoidosis remission: a 4-year longitudinal study.
 

Author(s): Katarina Osolnik, Matija Rijavec, Peter Korosec

Journal:

 

Invariant NKT (iNKT) cells are regulatory lymphocytes that may be important in disorders with increased Th1 responses. We utilized a 4-year longitudinal observational study of iNKT cells and SLAM signaling pathway factors, which are important for iNKT development in patients with ...

Last Updated: 4 Nov 2014

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Acute renal failure as a form of presentation of sarcoidosis in a young adult: a case report.
 

Author(s): Joana Rema, Margarida Carvalho, Raquel Vaz, Margarida Fonseca, Susana Sampaio, Augusta Pra├ža, Margarida Freitas-Silva, Teresa Cardoso

Journal:

 

Sarcoidosis is a systemic granulomatous disease. Renal involvement is a rare initial presentation of this disease. Few articles on renal involvement as an initial presentation of sarcoidosis have been published in the literature.

Last Updated: 20 Aug 2014

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[Granulomatous appendicitis caused by sarcoidosis: report of one case].
 

Author(s): Oscar Tapia E

Journal: Rev Med Chil. 2014 Apr;142(4):526-8.

 

Granulomatous appendicitis is uncommon and can be caused by Crohn's disease, foreign body reactions, infections or sarcoidosis. We report a 26-year-old female consulting in the emergency room for pain in the right lower abdomen. She was released with analgesics and consulted 14 days ...

Last Updated: 13 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Sarcoidosis" returned 141 free, full-text review articles on human participants. First 3 results:

Immunopathology of sarcoidosis.
 

Author(s): Esmaeil Mortaz, Mohammad Reza Masjedi, Payam Tabarsi, Mihan Pourabdollah, Ian M Adcock

Journal: Iran J Allergy Asthma Immunol. 2014 Oct;13(5):300-6.

 

The immunopathology of sarcoidosis remains elusive despite years of research into this multiorgan disease.However, recent studies have provided new insights into the genetics and immune components involved in the clinical manifestation of the disease. Granulomatous inflammation is ...

Last Updated: 23 Aug 2014

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The role of positron emission tomography-computed tomography/magnetic resonance imaging in the management of sarcoidosis patients.
 

Author(s): Chetsadaporn Promteangtrong, Ali Salavati, Gang Cheng, Drew A Torigian, Abass Alavi

Journal: Hell J Nucl Med. ;17(2):123-35.

 

Sarcoidosis is a multisystem granulomatous disease of unknown etiology. The diagnosis is based on clinical and radiographic findings as well as by histopathological findings. Molecular imaging in recent years has made important progress regarding the study of various inflammatory ...

Last Updated: 6 Aug 2014

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Cardiac involvement in sarcoidosis: evolving concepts in diagnosis and treatment.
 

Author(s): Joseph P Lynch, Jennifer Hwang, Jason Bradfield, Michael Fishbein, Kalyanam Shivkumar, Roderick Tung

Journal: Semin Respir Crit Care Med. 2014 Jun;35(3):372-90.

 

Clinically evident sarcoidosis involving the heart has been noted in at least 2 to 7% of patients with sarcoidosis, but occult involvement is much higher (> 20%). Cardiac sarcoidosis is often not recognized antemortem, as sudden death may be the presenting feature. Cardiac involvement ...

Last Updated: 10 Jul 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Cardiac Sarcoidosis: FDG PET vs. Ga-DOTANOC PET
 

Status: Recruiting

Condition Summary: Sarcoidosis; Cardiac Sarcoidosis

 

Last Updated: 26 Nov 2012

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Acthar Gel for Chronic Pulmonary Sarcoidosis (ACPS)
 

Status: Recruiting

Condition Summary: Sarcoidosis; Pulmonary Sarcoidosis

 

Last Updated: 26 Jan 2015

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ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot Study
 

Status: Not yet recruiting

Condition Summary: Sarcoidosis; Hypercalcemia Due to Sarcoidosis

 

Last Updated: 23 Jan 2015

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