Sarcoidosis

Common Name(s)

Sarcoidosis

Sarcoidosis is an inflammatory disease characterized by the development and growth of tiny lumps of cells called granulomas. If these tiny granulomas grow and clump together in an organ, they can affect how the organ works, leading to the symptoms of sarcoidosis. The granulomas can be found in almost any part of the body, but occur more commonly in the lungs, lymph nodes, eyes, skin, and liver.  Although no one is sure what causes sarcoidosis, it is thought by most scientists to be a disorder of the immune system.  The course of the disease varies from person to person. It often goes away on its own, but in some people symptoms of sarcoidosis may last a lifetime. For those who need treatment, anti-inflammatory medications can help.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sarcoidosis" for support, advocacy or research.

Logo
Foundation for Sarcoidosis Research

The Foundation for Sarcoidosis Research is the nation's leading nonprofit organization dedicated to finding a cure for this disease and to improving care for sarcoidosis patients. Since its establishment in 2000, FSR has funded numerous domestic and international research efforts and worked diligently to provide resources to thousands.

Last Updated: 19 Feb 2013

View Details
Logo
Janine's sarcoidosis outreach foundation

Our mission is to empower communities through Sarcoidosis Education and Outreach

Last Updated: 19 Feb 2013

View Details
Logo
Sarcoid Networking Association

The Sarcoid Networking Association was founded in 1992 to educate individuals, provide information and heighten public awareness about sarcoidosis.

Last Updated: 30 Apr 2014

View Details
Logo
Sarcoidosis Australia

Bring fellow sufferers together to support each other and their families Provide and share information and experiences, acting as a forum to help those affected to understand the condition Support the medical profession in the early diagnosis and treatment of those with these diseases Support the medical profession in research into the disease Heighten awareness of the disease in Australia

Last Updated: 2 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sarcoidosis" for support, advocacy or research.

Logo
Foundation for Sarcoidosis Research

The Foundation for Sarcoidosis Research is the nation's leading nonprofit organization dedicated to finding a cure for this disease and to improving care for sarcoidosis patients. Since its establishment in 2000, FSR has funded numerous domestic and international research efforts and worked diligently to provide resources to thousands.

http://www.stopsarcoidosis.org

Last Updated: 19 Feb 2013

View Details
Logo
Janine's sarcoidosis outreach foundation

Our mission is to empower communities through Sarcoidosis Education and Outreach

http://www.jsof.org

Last Updated: 19 Feb 2013

View Details
Logo
Sarcoid Networking Association

The Sarcoid Networking Association was founded in 1992 to educate individuals, provide information and heighten public awareness about sarcoidosis.

http://www.sarcoidosisnetwork.org

Last Updated: 30 Apr 2014

View Details
Logo
Sarcoidosis Australia

Bring fellow sufferers together to support each other and their families Provide and share information and experiences, acting as a forum to help those affected to understand the condition Support the medical profession in the early diagnosis and treatment of those with these diseases Support the medical profession in research into the disease Heighten awareness of the disease in Australia

http://www.sarcoidosisaustralia.com

Last Updated: 2 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Sarcoidosis" returned 1972 free, full-text research articles on human participants. First 3 results:

Upper Airway Obstruction Requiring Emergent Tracheostomy Secondary to Laryngeal Sarcoidosis: A Case Report.
 

Author(s): Changwan Ryu, Erica L Herzog, Hongyi Pan, Robert Homer, Mridu Gulati

Journal:

 

BACKGROUND Laryngeal sarcoidosis is a rare extrapulmonary manifestation of sarcoidosis, accounting for 0.33-2.1% of cases. A life-threatening complication of laryngeal sarcoidosis is upper airway obstruction. In this report we describe our experience in the acute and chronic care ...

Last Updated: 13 Feb 2017

Go To URL
[Pulmonary sarcoidosis presenting as multiple scattered pulmonary nodules: about a case].
 

Author(s): Haykel Abdelhedi, Naziha Khammassi, Amira Mhenni, Youssef Kort, Ouahida Cherif

Journal:

 

Sarcoidosis is a multisystem granulomatous disease that can affect all organs, thoracic involvement often predominates representing its most evocative manifestation. Atypical manifestations, such as the presence of multiple scattered pulmonary nodules may indicate malignancy. Our ...

Last Updated: 3 Feb 2017

Go To URL
Cardiac Sarcoidosis Diagnosed by Incidental Lymph Node Biopsy.
 

Author(s): Jun Matsuda, Katsuhito Fujiu, Solji Roh, Miyu Tajima, Hisataka Maki, Toshiya Kojima, Tetsuo Ushiku, Kan Nawata, Norihiko Takeda, Masafumi Watanabe, Hiroshi Akazawa, Issei Komuro

Journal: Int Heart J. 2017 Feb;58(1):140-143.

 

Cardiac involvement in systemic sarcoidosis sometimes provokes life-threatening ventricular tachyarrhythmia. Steroid administration is one of the fundamental anti-arrhythmia therapies. For an indication of steroid therapy, a definitive diagnosis of sarcoidosis is required.(1)) However, ...

Last Updated: 26 Jan 2017

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Sarcoidosis" returned 193 free, full-text review articles on human participants. First 3 results:

Cryptococcal meningitis complicating sarcoidosis.
 

Author(s): Sonja E Leonhard, Daan Fritz, Diederik van de Beek, Matthijs C Brouwer

Journal: Medicine (Baltimore). 2016 Aug;95(35):e4587.

 

Cryptococcal meningitis is an uncommon but severe complication of sarcoidosis.

Last Updated: 2 Sep 2016

Go To URL
Annexins family: insights into their functions and potential role in pathogenesis of sarcoidosis.
 

Author(s): Mehdi Mirsaeidi, Sanaz Gidfar, Ann Vu, Dean Schraufnagel

Journal:

 

Annexins are Ca(2+)-regulated phospholipid-binding proteins that play an important role in the cell life cycle, exocytosis, and apoptosis. Annexin A11 is one of the oldest vertebrate annexins that has a crucial role in sarcoidosis pathogenesis. The mechanism of effect in sarcoidosis ...

Last Updated: 13 Apr 2016

Go To URL
Evaluation of Known or Suspected Cardiac Sarcoidosis.
 

Author(s): Ron Blankstein, Alfonso H Waller

Journal: Circ Cardiovasc Imaging. 2016 Mar;9(3):e000867.

 

Sarcoidosis is a multisystem disorder of unknown cause, and cardiac sarcoidosis affects at least 25% of patients and accounts for substantial mortality and morbidity from this disease. Cardiac sarcoidosis may present with heart failure, left ventricular systolic dysfunction, AV block, ...

Last Updated: 1 Mar 2016

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Worldwide Sarcoidosis Research Study
 

Status: Recruiting

Condition Summary: Sarcoidosis

 

Last Updated: 27 May 2015

Go to URL
Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis
 

Status: Recruiting

Condition Summary: Sarcoidosis

 

Last Updated: 24 Jan 2017

Go to URL
Acthar Gel for Chronic Pulmonary Sarcoidosis (ACPS)
 

Status: Recruiting

Condition Summary: Sarcoidosis; Pulmonary Sarcoidosis

 

Last Updated: 4 Dec 2015

Go to URL