Sarcoidosis

Common Name(s)

Sarcoidosis

Sarcoidosis is an inflammatory disease characterized by the development and growth of tiny lumps of cells called granulomas. If these tiny granulomas grow and clump together in an organ, they can affect how the organ works, leading to the symptoms of sarcoidosis. The granulomas can be found in almost any part of the body, but occur more commonly in the lungs, lymph nodes, eyes, skin, and liver.  Although no one is sure what causes sarcoidosis, it is thought by most scientists to be a disorder of the immune system.  The course of the disease varies from person to person. It often goes away on its own, but in some people symptoms of sarcoidosis may last a lifetime. For those who need treatment, anti-inflammatory medications can help.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sarcoidosis" for support, advocacy or research.

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Foundation for Sarcoidosis Research

The Foundation for Sarcoidosis Research is the nation's leading nonprofit organization dedicated to finding a cure for this disease and to improving care for sarcoidosis patients. Since its establishment in 2000, FSR has funded numerous domestic and international research efforts and worked diligently to provide resources to thousands.

Last Updated: 19 Feb 2013

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Janine's sarcoidosis outreach foundation

Our mission is to empower communities through Sarcoidosis Education and Outreach

Last Updated: 19 Feb 2013

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Sarcoid Networking Association

The Sarcoid Networking Association was founded in 1992 to educate individuals, provide information and heighten public awareness about sarcoidosis.

Last Updated: 30 Apr 2014

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Sarcoidosis Australia

Bring fellow sufferers together to support each other and their families Provide and share information and experiences, acting as a forum to help those affected to understand the condition Support the medical profession in the early diagnosis and treatment of those with these diseases Support the medical profession in research into the disease Heighten awareness of the disease in Australia

Last Updated: 2 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sarcoidosis" for support, advocacy or research.

Logo
Foundation for Sarcoidosis Research

The Foundation for Sarcoidosis Research is the nation's leading nonprofit organization dedicated to finding a cure for this disease and to improving care for sarcoidosis patients. Since its establishment in 2000, FSR has funded numerous domestic and international research efforts and worked diligently to provide resources to thousands.

http://www.stopsarcoidosis.org

Last Updated: 19 Feb 2013

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Janine's sarcoidosis outreach foundation

Our mission is to empower communities through Sarcoidosis Education and Outreach

http://www.jsof.org

Last Updated: 19 Feb 2013

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Sarcoid Networking Association

The Sarcoid Networking Association was founded in 1992 to educate individuals, provide information and heighten public awareness about sarcoidosis.

http://www.sarcoidosisnetwork.org

Last Updated: 30 Apr 2014

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Sarcoidosis Australia

Bring fellow sufferers together to support each other and their families Provide and share information and experiences, acting as a forum to help those affected to understand the condition Support the medical profession in the early diagnosis and treatment of those with these diseases Support the medical profession in research into the disease Heighten awareness of the disease in Australia

http://www.sarcoidosisaustralia.com

Last Updated: 2 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Sarcoidosis" returned 1968 free, full-text research articles on human participants. First 3 results:

Sarcoidosis and Autoimmunity: From Genetic Background to Environmental Factors.
 

Author(s): Sara Bindoli, Amir Dagan, José J Torres-Ruiz, Carlo Perricone, Mojca Bizjak, Andrea Doria, Yehuda Shoenfeld

Journal: Isr. Med. Assoc. J.. ;18(3-4):197-202.

 

Sarcoidosis is a chronic multisystem disease with variable course resulting from the interaction between environmental factors and the immune system of individuals genetically predisposed. The evidence linking sarcoidosis with environmental triggers such as metals is increasing. We ...

Last Updated: 27 May 2016

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Altered miRNA expression in pulmonary sarcoidosis.
 

Author(s): Justyna Kiszałkiewicz, Wojciech J Piotrowski, Dorota Pastuszak-Lewandoska, Paweł Górski, Adam Antczak, Witold Górski, Daria Domańska-Senderowska, Monika Migdalska-Sęk, Karolina H Czarnecka, Ewa Nawrot, Ewa Brzeziańska-Lasota

Journal:

 

miRNAs control important cellular functions including angiogenesis/angiostasis or fibrosis and reveal altered expression during pathological processes in the lung.

Last Updated: 15 Jan 2016

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Prognosis of Myocardial Damage in Sarcoidosis Patients With Preserved Left Ventricular Ejection Fraction: Risk Stratification Using Cardiovascular Magnetic Resonance.
 

Author(s): Gillian Murtagh, Luke J Laffin, John F Beshai, Francesco Maffessanti, Catherine A Bonham, Amit V Patel, Zoe Yu, Karima Addetia, Victor Mor-Avi, Joshua D Moss, D Kyle Hogarth, Nadera J Sweiss, Roberto M Lang, Amit R Patel

Journal: Circ Cardiovasc Imaging. 2016 Jan;9(1):e003738.

 

Cardiac sarcoidosis is associated with an increased risk of heart failure and sudden death, but its risk in patients with preserved left ventricular ejection fraction is unknown. Using cardiovascular magnetic resonance in patients with extracardiac sarcoidosis and preserved left ventricular ...

Last Updated: 14 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Sarcoidosis" returned 179 free, full-text review articles on human participants. First 3 results:

Selected molecular events in the pathogenesis of sarcoidosis - recent advances.
 

Author(s): Justyna Kiszałkiewicz, Wojciech J Piotrowski, Ewa Brzeziańska-Lasota

Journal: Pneumonol Alergol Pol. 2015 ;83(6):462-75.

 

Sarcoidosis is an orphan inflammatory disorder that can virtually affect any organ or system in the body, although the lungs and lymph nodes are most frequently involved. Sarcoidosis is believed to derive from an interaction between environmental and genetic agents. Many studies emphasize ...

Last Updated: 12 Nov 2015

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Sarcoidosis Occurring After Solid Cancer: A Nonfortuitous Association: Report of 12 Cases and Review of the Literature.
 

Author(s): Aurélie Grados, Mikael Ebbo, Emmanuelle Bernit, Véronique Veit, Karin Mazodier, Rodolphe Jean, Diane Coso, Thérèse Aurran-Schleinitz, Florence Broussais, Reda Bouabdallah, Gwenaelle Gravis, Anthony Goncalves, Marc Giovaninni, Pascal Sève, Bruno Chetaille, Florence Gavet-Bongo, Thierry Weitten, Michel Pavic, Jean-Robert Harlé, Nicolas Schleinitz

Journal: Medicine (Baltimore). 2015 Jul;94(28):e928.

 

The association between cancer and sarcoidosis is controversial. Some epidemiological studies show an increase of the incidence of cancer in patients with sarcoidosis but only few cases of sarcoidosis following cancer treatment have been reported. We conducted a retrospective case ...

Last Updated: 18 Jul 2015

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Electrophysiological correlates of cardiac sarcoidosis: an appraisal of current evidence.
 

Author(s): Mrinal Yadava, Rupa Bala

Journal: Turk Kardiyol Dern Ars. 2015 Jun;43(4):392-401.

 

Cardiac sarcoidosis is an underdiagnosed condition that may be present in as many as 25% of patients with systemic sarcoidosis. It is associated with significant morbidity and mortality in affected individuals. The presentation of cardiac involvement in sarcoidosis includes sudden ...

Last Updated: 6 Jul 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Acthar Gel for Chronic Pulmonary Sarcoidosis (ACPS)
 

Status: Recruiting

Condition Summary: Sarcoidosis; Pulmonary Sarcoidosis

 

Last Updated: 4 Dec 2015

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ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot Study
 

Status: Not yet recruiting

Condition Summary: Sarcoidosis; Hypercalcemia Due to Sarcoidosis

 

Last Updated: 23 Jan 2015

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Worldwide Sarcoidosis Research Study
 

Status: Recruiting

Condition Summary: Sarcoidosis

 

Last Updated: 27 May 2015

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