Sarcoidosis

Common Name(s)

Sarcoidosis

Sarcoidosis is an inflammatory disease characterized by the development and growth of tiny lumps of cells called granulomas. If these tiny granulomas grow and clump together in an organ, they can affect how the organ works, leading to the symptoms of sarcoidosis. The granulomas can be found in almost any part of the body, but occur more commonly in the lungs, lymph nodes, eyes, skin, and liver.  Although no one is sure what causes sarcoidosis, it is thought by most scientists to be a disorder of the immune system.  The course of the disease varies from person to person. It often goes away on its own, but in some people symptoms of sarcoidosis may last a lifetime. For those who need treatment, anti-inflammatory medications can help.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sarcoidosis" for support, advocacy or research.

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Foundation for Sarcoidosis Research

The Foundation for Sarcoidosis Research is the nation's leading nonprofit organization dedicated to finding a cure for this disease and to improving care for sarcoidosis patients. Since its establishment in 2000, FSR has funded numerous domestic and international research efforts and worked diligently to provide resources to thousands.

Last Updated: 19 Feb 2013

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Janine's sarcoidosis outreach foundation

Our mission is to empower communities through Sarcoidosis Education and Outreach

Last Updated: 19 Feb 2013

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Sarcoid Networking Association

The Sarcoid Networking Association was founded in 1992 to educate individuals, provide information and heighten public awareness about sarcoidosis.

Last Updated: 30 Apr 2014

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Sarcoidosis Australia

Bring fellow sufferers together to support each other and their families Provide and share information and experiences, acting as a forum to help those affected to understand the condition Support the medical profession in the early diagnosis and treatment of those with these diseases Support the medical profession in research into the disease Heighten awareness of the disease in Australia

Last Updated: 2 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sarcoidosis" for support, advocacy or research.

Logo
Foundation for Sarcoidosis Research

The Foundation for Sarcoidosis Research is the nation's leading nonprofit organization dedicated to finding a cure for this disease and to improving care for sarcoidosis patients. Since its establishment in 2000, FSR has funded numerous domestic and international research efforts and worked diligently to provide resources to thousands.

http://www.stopsarcoidosis.org

Last Updated: 19 Feb 2013

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Janine's sarcoidosis outreach foundation

Our mission is to empower communities through Sarcoidosis Education and Outreach

http://www.jsof.org

Last Updated: 19 Feb 2013

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Sarcoid Networking Association

The Sarcoid Networking Association was founded in 1992 to educate individuals, provide information and heighten public awareness about sarcoidosis.

http://www.sarcoidosisnetwork.org

Last Updated: 30 Apr 2014

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Sarcoidosis Australia

Bring fellow sufferers together to support each other and their families Provide and share information and experiences, acting as a forum to help those affected to understand the condition Support the medical profession in the early diagnosis and treatment of those with these diseases Support the medical profession in research into the disease Heighten awareness of the disease in Australia

http://www.sarcoidosisaustralia.com

Last Updated: 2 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Sarcoidosis" returned 2017 free, full-text research articles on human participants. First 3 results:

Sarcoidosis and Autoimmunity: From Genetic Background to Environmental Factors.
 

Author(s): Sara Bindoli, Amir Dagan, José J Torres-Ruiz, Carlo Perricone, Mojca Bizjak, Andrea Doria, Yehuda Shoenfeld

Journal: Isr. Med. Assoc. J.. ;18(3-4):197-202.

 

Sarcoidosis is a chronic multisystem disease with variable course resulting from the interaction between environmental factors and the immune system of individuals genetically predisposed. The evidence linking sarcoidosis with environmental triggers such as metals is increasing. We ...

Last Updated: 27 May 2016

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In-Hospital Disease Burden of Sarcoidosis in Switzerland from 2002 to 2012.
 

Author(s): Susanne Pohle, Florent Baty, Martin Brutsche

Journal:

 

Sarcoidosis is a multisystem disease with an unpredictable and sometimes fatal course while the underlying pathomechanism is still unclear. Reasons of the increasing hospitalization rate and mortality in the United States remain in dispute but incriminated are a number of distinct ...

Last Updated: 18 Mar 2016

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Effects of radiological extent on neutrophil/lymphocyte ratio in pulmonary sarcoidosis.
 

Author(s): N Ocal, D Dogan, R Ocal, E Tozkoparan, O Deniz, E Ucar, S Gumus, C Tasci, B Yildiz, G Taskin, A Taskin, S Badem, U Turhan

Journal: Eur Rev Med Pharmacol Sci. 2016 ;20(4):709-14.

 

Determining the severity of sarcoidosis is based on the clinical and radiological findings of the disease and the changes in pulmonary function test results. On the other hand; studies are ongoing for objective and easy markers in this respect. Neutrophil/lymphocyte ratio (NLR) is ...

Last Updated: 9 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Sarcoidosis" returned 193 free, full-text review articles on human participants. First 3 results:

Annexins family: insights into their functions and potential role in pathogenesis of sarcoidosis.
 

Author(s): Mehdi Mirsaeidi, Sanaz Gidfar, Ann Vu, Dean Schraufnagel

Journal:

 

Annexins are Ca(2+)-regulated phospholipid-binding proteins that play an important role in the cell life cycle, exocytosis, and apoptosis. Annexin A11 is one of the oldest vertebrate annexins that has a crucial role in sarcoidosis pathogenesis. The mechanism of effect in sarcoidosis ...

Last Updated: 13 Apr 2016

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Ocular Sarcoidosis.
 

Author(s): Sirichai Pasadhika, James T Rosenbaum

Journal: Clin. Chest Med.. 2015 Dec;36(4):669-83.

 

Sarcoidosis is one of the leading causes of inflammatory eye disease. Ocular sarcoidosis can involve any part of the eye and its adnexal tissues and may cause uveitis, episcleritis/scleritis, eyelid abnormalities, conjunctival granuloma, optic neuropathy, lacrimal gland enlargement, ...

Last Updated: 23 Nov 2015

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Identifying Novel Biomarkers in Sarcoidosis Using Genome-Based Approaches.
 

Author(s): Nancy Casanova, Tong Zhou, Kenneth S Knox, Joe G N Garcia

Journal: Clin. Chest Med.. 2015 Dec;36(4):621-30.

 

This article briefly reviews conventional biomarkers used clinically to (1) support a diagnosis and (2) monitor disease progression in patients with sarcoidosis. Potential new biomarkers identified by genome-wide screening and the approaches to discover these biomarkers are described.

Last Updated: 23 Nov 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Worldwide Sarcoidosis Research Study
 

Status: Recruiting

Condition Summary: Sarcoidosis

 

Last Updated: 27 May 2015

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Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis
 

Status: Recruiting

Condition Summary: Sarcoidosis

 

Last Updated: 18 Nov 2015

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Acthar Gel for Chronic Pulmonary Sarcoidosis (ACPS)
 

Status: Recruiting

Condition Summary: Sarcoidosis; Pulmonary Sarcoidosis

 

Last Updated: 4 Dec 2015

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