Ataxia

Common Name(s)

Ataxia

Ataxia occurs as a result of damage to a part of the brain called the cerebellum which controls muscle movement. Other causes of ataxia include alcohol abuse, stroke, tumor, cerebral palsy or multiple sclerosis. Ataxia can be passed on through your genes without your parents ever showing symptoms of having the disease. Common symptoms of ataxia include slurred speech, difficulty walking, losing your balance and having trouble swallowing. As ataxia develops, it may become harder to walk, button up shirts, grasp small objects, swallow food/saliva or control your eye movements. Treatment for ataxia includes physical therapy, occupational therapy and/or speech therapy depending on what type of ataxia you have been diagnosed with.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ataxia" for support, advocacy or research.

Movement Disorder Society

The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.

Last Updated: 5 May 2014

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National Ataxia Foundation

The National Ataxia Foundation is dedicated to improving the lives of persons affected by ataxia through support, education, and research.

Last Updated: 12 Dec 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ataxia" for support, advocacy or research.

Movement Disorder Society

The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.

http://www.movementdisorders.org/MDS.htm

Last Updated: 5 May 2014

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National Ataxia Foundation

The National Ataxia Foundation is dedicated to improving the lives of persons affected by ataxia through support, education, and research.

http://www.ataxia.org

Last Updated: 12 Dec 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ataxia" returned 1466 free, full-text research articles on human participants. First 3 results:

Ataxia-telangiectasia with novel splicing mutations in the ATM gene.
 

Author(s): Heejeong Jeong, Hee Jae Huh, Jinyoung Youn, Ji Sun Kim, Jin Whan Cho, Chang-Seok Ki

Journal: Ann Lab Med. 2014 Jan;34(1):80-4.

 

Last Updated: 14 Jan 2014

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Inhibition of ataxia telangiectasia mutated (ATM) kinase suppresses herpes simplex virus type 1 (HSV-1) keratitis.
 

Author(s): Oleg Alekseev, Kelly Donovan, Jane Azizkhan-Clifford

Journal:

 

Herpes keratitis (HK) remains the leading cause of cornea-derived blindness in the developed world, despite the availability of effective antiviral drugs. Treatment toxicity and the emergence of drug resistance highlight the need for additional therapeutic approaches. This study examined ...

Last Updated: 4 Feb 2014

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Spinal cord atrophy in spinocerebellar ataxia type 1.
 

Author(s): José Luiz Pedroso, Orlando G P Barsottini

Journal: Arq Neuropsiquiatr. 2013 Dec;71(12):977.

 

Last Updated: 18 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ataxia" returned 103 free, full-text review articles on human participants. First 3 results:

Prevalence of ataxia in children: a systematic review.
 

Author(s): Kristin E Musselman, Cristina T Stoyanov, Rhul Marasigan, Mary E Jenkins, Jürgen Konczak, Susanne M Morton, Amy J Bastian

Journal: Neurology. 2014 Jan;82(1):80-9.

 

To estimate the prevalence of childhood ataxia resulting from both genetic and acquired causes.

Last Updated: 31 Dec 2013

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Friedreich's ataxia, frataxin, PIP5K1B: echo of a distant fracas.
 

Author(s): Aurélien Bayot, Pierre Rustin

Journal: Oxid Med Cell Longev. 2013 ;2013():725635.

 

"Frataxin fracas" were the words used when referring to the frataxin-encoding gene (FXN) burst in as a motive to disqualify an alternative candidate gene, PIP5K1B, as an actor in Friedreich's ataxia (FRDA) (Campuzano et al., 1996; Cossee et al., 1997; Carvajal et al., 1996). The instrumental ...

Last Updated: 6 Nov 2013

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[Chronic ataxia in childhood].
 

Author(s): Ricardo Erazo Torricelli

Journal: Medicina (B Aires). 2013 ;73 Suppl 1():38-48.

 

Chronic ataxias are an heterogeneous group of disorders that affect the child at different ages. Thus, the congenital forms, generally non progressive are observed from first months of life and are expressed by hypotonia and motor delay long before the ataxia became evident. The cerebral ...

Last Updated: 27 Sep 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias
 

Status: Recruiting

Condition Summary: Spinocerebellar Ataxia Type 1; Spinocerebellar Ataxia Type 2; Spinocerebellar Ataxia Type 3; Spinocerebellar Ataxia Type 6

 

Last Updated: 20 May 2014

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Phenotypic and Genotypic Studies in Congenital and Early Onset Ataxias
 

Status: Recruiting

Condition Summary: Congenital Cerebellar Ataxias; Early-onset Cerebellar Ataxias

 

Last Updated: 26 Feb 2014

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Immunogenicity of Pneumococcal Vaccines in Ataxia-telangiectasia Patients
 

Status: Not yet recruiting

Condition Summary: Ataxia Telangiectasia

 

Last Updated: 15 Mar 2010

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