Rocky mountain spotted fever

Common Name(s)

Rocky mountain spotted fever

Rocky Mountain spotted fever (RMSF) is a disease that primarily affects those in North and South America, transmitted to humans by the bite of infected ticks. RMSF cases have been reported throughout most of the United States, though the states of North Carolina, Oklahoma, Arkansas, Tennessee, and Missouri account for over 60% of cases, with the majority of cases reported have peaked during the summer months in June and July. Children under 10 years old, Native Americans, people with a compromised immune system, and people with delayed treatment are most at risk of a fatal outcome from RMSF. Signs and symptoms of RMSF include fever, headache, abdominal pain, rash, vomiting, and muscle pain. If not treated immediately, RMSF can be a severe or even fatal illness. RMSF and other tick-borne diseases are preventable.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Rocky mountain spotted fever" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Rocky mountain spotted fever" returned 74 free, full-text research articles on human participants. First 3 results:

No visible dental staining in children treated with doxycycline for suspected Rocky Mountain Spotted Fever.
 

Author(s): Suzanne R Todd, F Scott Dahlgren, Marc S Traeger, Eugenio D Beltrán-Aguilar, Donald W Marianos, Charlene Hamilton, Jennifer H McQuiston, Joanna J Regan

Journal: J. Pediatr.. 2015 May;166(5):1246-51.

 

To evaluate whether cosmetically relevant dental effects occurred among children who had received doxycycline for treatment of suspected Rocky Mountain spotted fever (RMSF).

Last Updated: 29 Apr 2015

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Rocky mountain spotted fever characterization and comparison to similar illnesses in a highly endemic area-Arizona, 2002-2011.
 

Author(s): Marc S Traeger, Joanna J Regan, Dwight Humpherys, Dianna L Mahoney, Michelle Martinez, Ginny L Emerson, Danielle M Tack, Aimee Geissler, Seema Yasmin, Regina Lawson, Charlene Hamilton, Velda Williams, Craig Levy, Kenneth Komatsu, Jennifer H McQuiston, David A Yost

Journal: Clin. Infect. Dis.. 2015 Jun;60(11):1650-8.

 

Rocky Mountain spotted fever (RMSF) has emerged as a significant cause of morbidity and mortality since 2002 on tribal lands in Arizona. The explosive nature of this outbreak and the recognition of an unexpected tick vector, Rhipicephalus sanguineus, prompted an investigation to characterize ...

Last Updated: 14 May 2015

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Risk factors for fatal outcome from rocky mountain spotted Fever in a highly endemic area-Arizona, 2002-2011.
 

Author(s): Joanna J Regan, Marc S Traeger, Dwight Humpherys, Dianna L Mahoney, Michelle Martinez, Ginny L Emerson, Danielle M Tack, Aimee Geissler, Seema Yasmin, Regina Lawson, Velda Williams, Charlene Hamilton, Craig Levy, Ken Komatsu, David A Yost, Jennifer H McQuiston

Journal: Clin. Infect. Dis.. 2015 Jun;60(11):1659-66.

 

Rocky Mountain spotted fever (RMSF) is a disease that now causes significant morbidity and mortality on several American Indian reservations in Arizona. Although the disease is treatable, reported RMSF case fatality rates from this region are high (7%) compared to the rest of the ...

Last Updated: 14 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Rocky mountain spotted fever" returned 4 free, full-text review articles on human participants. First 3 results:

Hemostatic changes in Rocky Mountain spotted fever and Mediterranean spotted fever.
 

Author(s): M T Elghetany, D H Walker

Journal: Am. J. Clin. Pathol.. 1999 Aug;112(2):159-68.

 

Rocky Mountain spotted fever and Mediterranean spotted fever are rickettsial infections primarily of endothelial cells that normally have a potent anticoagulant function. As a result of endothelial cell infection and injury, the hemostatic system is perturbed and shows changes that ...

Last Updated: 24 Aug 1999

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Rocky mountain spotted fever.
 

Author(s): A R Thorner, D H Walker, W A Petri

Journal: Clin. Infect. Dis.. 1998 Dec;27(6):1353-9; quiz 1360.

 

Last Updated: 8 Mar 1999

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Rocky Mountain spotted fever: a disease in need of microbiological concern.
 

Author(s): D H Walker

Journal: Clin. Microbiol. Rev.. 1989 Jul;2(3):227-40.

 

Rocky Mountain spotted fever, a life-threatening tick-transmitted infection, is the most prevalent rickettsiosis in the United States. This zoonosis is firmly entrenched in the tick host, which maintains the rickettsiae in nature by transovarian transmission. Although the incidence ...

Last Updated: 27 Sep 1989

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
 

Status: Recruiting

Condition Summary: Infection; Hypertension; Pain; Reflux; Edema; Hyperlipidemia; Hypotension; Hypercholesterolemia; Sedation; Anxiolysis; Benzodiazepine Withdrawal; Bipolar Disorder; Autistic Disorder; Schizophrenia; Influenza Treatment or Prophylaxis; Acute Decompensated Heart Failure; Stable Angina; Life-threatening Fungal Infections; Nosocomial Pneumonia; Community Acquired Pneumonia; Acute Bacterial Exacerbation of Chronic Bronchitis; Complicated Skin and Skin Structure Infections; Uncomplicated Skin and Skin Structure Infections; Chronic Bacterial Prostatitis; Complicated Urinary Tract Infections; Acute Pyelonephritis; Uncomplicated Urinary Tract Infections; Inhalational Anthrax (Post-Exposure); Infantile Hemangioma; Withdrawal; Inflammation; Bacterial Septicemia; Cytomegalovirus Retinitis; Herpes Simplex Virus; Adenovirus; Brain Swelling; Airway Swelling; Adrenal Insufficiency; Anxiety; Nausea; Vomiting; Convulsions; Muscle Spasms; Seizures; Epilepsy; Bartonellosis; Brucellosis; Cholera; Plague; Psittacosis; Q Fever; Relapsing Fever; Rocky Mountain Spotted Fever; Trachoma; Tularemia; Typhus Fever; Bronchospasm; Cardiac Arrest; Hypersensitivity Reaction; Cyanide Poisoning; Acute Bacterial Sinusitis; Bacterial Meningitis; Sepsis; Gastroparesis; Opioid Addiction; Migraines; Headaches

 

Last Updated: 4 Feb 2016

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