Ring Chromosomes

Common Name(s)

Ring Chromosomes

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ring Chromosomes" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ring Chromosomes" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ring Chromosomes" returned 19 free, full-text research articles on human participants. First 3 results:

Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells.
 

Author(s): Marina Bershteyn, Yohei Hayashi, Guillaume Desachy, Edward C Hsiao, Salma Sami, Kathryn M Tsang, Lauren A Weiss, Arnold R Kriegstein, Shinya Yamanaka, Anthony Wynshaw-Boris

Journal: Nature. 2014 Mar;507(7490):99-103.

 

Ring chromosomes are structural aberrations commonly associated with birth defects, mental disabilities and growth retardation. Rings form after fusion of the long and short arms of a chromosome, and are sometimes associated with large terminal deletions. Owing to the severity of ...

Last Updated: 6 Mar 2014

Go To URL
Duplications in addition to terminal deletions are present in a proportion of ring chromosomes: clues to the mechanisms of formation.
 

Author(s): E Rossi, M Riegel, J Messa, S Gimelli, P Maraschio, R Ciccone, M Stroppi, P Riva, C S Perrotta, T Mattina, L Memo, A Baumer, V Kucinskas, C Castellan, A Schinzel, O Zuffardi

Journal: J. Med. Genet.. 2008 Mar;45(3):147-54.

 

Ring chromosomes are often associated with abnormal phenotypes because of loss of genomic material at one or both ends. In some cases no deletion has been detected and the abnormal phenotype has been attributed to mitotic ring instability. We investigated 33 different ring chromosomes ...

Last Updated: 3 Mar 2008

Go To URL
Telomere-independent homologue pairing and checkpoint escape of accessory ring chromosomes in male mouse meiosis.
 

Author(s): Thierry Voet, Bodo Liebe, Charlotte Labaere, Peter Marynen, Harry Scherthan

Journal: J. Cell Biol.. 2003 Sep;162(5):795-807.

 

We analyzed transmission of a ring minichromosome (MC) through mouse spermatogenesis as a monosome and in the presence of a homologue. Mice, either monosomic or disomic for the MC, produced MC+ offspring. In the monosomic condition, most univalents underwent self-synapsis as indicated ...

Last Updated: 3 Sep 2003

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ring Chromosomes" returned 1 free, full-text review articles on human participants. First 3 results:

Constitutional ring chromosomes and tumour suppressor genes.
 

Author(s): N Tommerup, R Lothe

Journal: J. Med. Genet.. 1992 Dec;29(12):879-82.

 

The types of malignancy reported in carriers of constitutional ring chromosomes r(11), r(13), and r(22) are concordant with the chromosomal assignment of tumour suppressor loci associated with Wilms' tumour, retinoblastoma, and meningioma. It is suggested that the somatic instability ...

Last Updated: 9 Feb 1993

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.