Asthma

Common Name(s)

Asthma

Asthma is a chronic (long-term), inflammatory condition affecting the airways. The causes of asthma may be environmental, genetic, or both.

There are many risk factors that may increase the chances of having asthma, some of which can be controlled but others cannot. In childhood, males are more likely to have asthma than females but this trend reverses in adulthood. Allergic hypersensitivity (atopy) and sleep apnea often coexist with asthma. Obesity, cigarette smoking, pregnancy, and environmental factors such as pollution, cold air, or high humidity may also be risk factors for asthma.

Common symptoms of asthma include coughing, wheezing, shortness of breath, and chest tightness. Symptoms often come and go and there can be different triggers for acute (sudden, severe) attacks in different people. When there is a trigger (typically allergens such as pet dander, dust mites, mold etc.), inflammation of the airways occurs. The muscles in that area tighten up making a smaller opening for air to pass through. This tightening causes breathing difficulties and common symptoms. Many people with asthma also have a personal or family history of allergies, hay fever, or eczema. There is no diagnostic test for asthma, but through examining symptoms, risk factors, and response to appropriate therapies, one may be diagnosed with the condition.

Unfortunately, there is no cure for asthma at this time. However, there are management options that can limit or improve the response to the symptoms including medications and life style changes. Most people with asthma lead normal lives. If you or your child has asthma, talk to your doctor to discuss the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Asthma" for support, advocacy or research.

Logo
Allergy & Asthma Network Mothers of Asthmatics

Allergy & Asthma Network Mothers of Asthmatics (AANMA) is the leading national non-profit organization dedicated to eliminating needless death and suffering due to asthma, allergies and related conditions through education, community outreach, advocacy and research. AANMA facilitates communication of quality information among patients, parents, physicians, community members, government and private industry through accurate guidance and clearly written resources on asthma and allergies, provided through its website, aanma.org, published reports, position statements, quarterly magazine, Allergy & Asthma Today, and monthly newsletter, The MA Report.

Last Updated: 15 Feb 2013

View Details
Logo
American Lung Association

The American Lung Association is the leading organization working to save lives, improve lung health and prevent lung disease. The American Lung Association is "Fighting for Air" through research, education and advocacy.

Last Updated: 17 May 2010

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

View Details
Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Asthma" for support, advocacy or research.

Logo
Allergy & Asthma Network Mothers of Asthmatics

Allergy & Asthma Network Mothers of Asthmatics (AANMA) is the leading national non-profit organization dedicated to eliminating needless death and suffering due to asthma, allergies and related conditions through education, community outreach, advocacy and research. AANMA facilitates communication of quality information among patients, parents, physicians, community members, government and private industry through accurate guidance and clearly written resources on asthma and allergies, provided through its website, aanma.org, published reports, position statements, quarterly magazine, Allergy & Asthma Today, and monthly newsletter, The MA Report.

http://www.aanma.org

Last Updated: 15 Feb 2013

View Details
Logo
American Lung Association

The American Lung Association is the leading organization working to save lives, improve lung health and prevent lung disease. The American Lung Association is "Fighting for Air" through research, education and advocacy.

http://www.lungusa.org

Last Updated: 17 May 2010

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

View Details
Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Asthma" returned 9472 free, full-text research articles on human participants. First 3 results:

Effect of Antibiotics on Polymorphonuclear Leukocyte Functions and Myeloperoxidase Activity, Glutathione and Malondialdehyde Levels in Allergic Asthma.
 

Author(s): Pervin Rayaman, Erkan Rayaman, Adile Cevikbaş, Refik Demirtunç, Ahmet Ozer Sehirli, Seyda Gül Alagöz, Umran Soyoğul Gürer

Journal: Pol. J. Microbiol.. 2015 ;64(1):69-72.

 

We investigated the effect of ciprofloxacin, rifampicine and doxycycline on myeloperoxidase (MPO) activity, glutathione (GSH) and malondialdehyde (MDA) levels in allergic asthma patients and healthy volunteers. Polymorphonuclear leukocytes (PMNs) were isolated with ficoll-hypaque ...

Last Updated: 22 Jun 2015

Go To URL
[Genome wide expression analysis of the effect of Socheongryong Tang in asthma model of mice].
 

Author(s): Chi-Yeon Lim, Hyung-Woo Kim, Bu-Yeo Kim, Su-In Cho

Journal: J Tradit Chin Med. 2015 Apr;35(2):168-74.

 

To investigate the molecular effect of Socheongryong Tang (SCRT, Xiaoqinglong Tang in Chinese) on whole genome level in asthma mouse model by microarray technology.

Last Updated: 15 May 2015

Go To URL
Work-related asthma cluster at a syntactic foam manufacturing facility - Massachusetts 2008-2013.
 

Author(s): Megan Casey, Marcia L Stanton, Kristin J Cummings, Elise Pechter, Kathleen Fitzsimmons, Ryan F LeBouf, Christine R Schuler, Kathleen Kreiss

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2015 Apr;64(15):411-4.

 

Work-related asthma is asthma that is caused or exacerbated by exposure to specific substances in the workplace. Approximately 10%-16% of adult-onset asthma cases are attributable to occupational factors, and estimates of asthma exacerbated by work range from 13% to 58%. During 2008-2012, ...

Last Updated: 24 Apr 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Asthma" returned 1491 free, full-text review articles on human participants. First 3 results:

[Bronchial thermoplasty; a new treatment modality in asthma].
 

Author(s): Zehra Yaşar, Erdoğan Çetinkaya

Journal: Tuberk Toraks. 2014 ;62(4):291-300.

 

Bronchial thermoplasty is a non-drug treatment modality for moderate-to-severe asthma that involves the delivery of radio frequency energy to the airway wall in a precisely controlled manner to reduce excessive airway smooth muscle. Bronchial thermoplasty is performed under conscious ...

Last Updated: 13 Jan 2015

Go To URL
Childhood asthma: causes, risks, and protective factors; a role of innate immunity.
 

Author(s): Georgios T Noutsios, Joanna Floros

Journal:

 

Childhood asthma is an umbrella of multifactorial diseases with similar clinical features such as mast cell and eosinophil infiltration causing airway hyper responsiveness, inflammation, and airway obstruction. There are various factors that are implicated in childhood asthma pathogenesis. ...

Last Updated: 25 Dec 2014

Go To URL
Type 2 inflammation in asthma--present in most, absent in many.
 

Author(s): John V Fahy

Journal: Nat. Rev. Immunol.. 2015 Jan;15(1):57-65.

 

Asthma is one of the most common chronic immunological diseases in humans, affecting people from childhood to old age. Progress in treating asthma has been relatively slow and treatment guidelines have mostly recommended empirical approaches on the basis of clinical measures of disease ...

Last Updated: 23 Dec 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Asthma Inflammation Research
 

Status: Recruiting

Condition Summary: Asthma; Allergic Asthma; Non-allergic Asthma

 

Last Updated: 2 Feb 2015

Go to URL
Asthma Self-management Via Application of Telehealth
 

Status: Recruiting

Condition Summary: Asthma; Mixed Asthma With Acute Exacerbation

 

Last Updated: 15 Apr 2015

Go to URL
Unravelling Targets of Therapy in Bronchial Thermoplasty in Severe Asthma
 

Status: Recruiting

Condition Summary: Asthma; Bronchial Asthma

 

Last Updated: 23 Jun 2015

Go to URL