Rickets

Common Name(s)

Rickets

Rickets is a condition that causes children to have soft, weak bones. It usually occurs when children do not get enough vitamin D, which helps growing bones absorb important nutrients. Vitamin D comes from sunlight and food. Skin produces vitamin D in response to the sun's rays. Some foods also contain vitamin D, including fortified dairy products and cereals, and some kinds of fish.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Rickets" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Rickets" returned 408 free, full-text research articles on human participants. First 3 results:

Case report of an infant with severe vitamin D deficiency rickets manifested as hypocalcemic seizures.
 

Author(s): Biljana Vuletić, Slavica Marković, Zoran Igrutinović, Radlović Vladimir, Zorica Rasković, Aleksandra Simović

Journal: Srp Arh Celok Lek. ;144(1-2):90-3.

 

Hypocalcemic seizures are uncommon in the post-neonatal period. We report an infant with hypocalcemic seizures caused by severe deficiency of vitamin D.

Last Updated: 9 Jun 2016

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Global Consensus Recommendations on Prevention and Management of Nutritional Rickets.
 

Author(s): Craig F Munns, Nick Shaw, Mairead Kiely, Bonny L Specker, Tom D Thacher, Keiichi Ozono, Toshimi Michigami, Dov Tiosano, M Zulf Mughal, Outi Mäkitie, Lorna Ramos-Abad, Leanne Ward, Linda A DiMeglio, Navoda Atapattu, Hamilton Cassinelli, Christian Braegger, John M Pettifor, Anju Seth, Hafsatu Wasagu Idris, Vijayalakshmi Bhatia, Junfen Fu, Gail Goldberg, Lars Sävendahl, Rajesh Khadgawat, Pawel Pludowski, Jane Maddock, Elina Hyppönen, Abiola Oduwole, Emma Frew, Magda Aguiar, Ted Tulchinsky, Gary Butler, Wolfgang Högler

Journal: Horm Res Paediatr. 2016 ;85(2):83-106.

 

Vitamin D and calcium deficiencies are common worldwide, causing nutritional rickets and osteomalacia, which have a major impact on health, growth, and development of infants, children, and adolescents; the consequences can be lethal or can last into adulthood. The goals of this evidence-based ...

Last Updated: 29 Jan 2016

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Novel Vitamin D Receptor Mutations in Hereditary Vitamin D Resistant Rickets in Chinese.
 

Author(s): Lee-Moay Lim, Xuan Zhao, Mei-Chyn Chao, Jer-Ming Chang, Wei-Chiao Chang, Hung-Ying Kao, Daw-Yang Hwang, Hung-Chun Chen

Journal:

 

Hereditary 1, 25-dihydroxyvitamin D-resistant rickets (HVDRR), a rare recessive disease, is caused by mutation in the VDR gene encoding the vitamin D receptor leading to the resistance to vitamin D. We described a female toddler with initial presentation of leg tenderness and clinical ...

Last Updated: 1 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Rickets" returned 26 free, full-text review articles on human participants. First 3 results:

Global Consensus Recommendations on Prevention and Management of Nutritional Rickets.
 

Author(s): Craig F Munns, Nick Shaw, Mairead Kiely, Bonny L Specker, Tom D Thacher, Keiichi Ozono, Toshimi Michigami, Dov Tiosano, M Zulf Mughal, Outi Mäkitie, Lorna Ramos-Abad, Leanne Ward, Linda A DiMeglio, Navoda Atapattu, Hamilton Cassinelli, Christian Braegger, John M Pettifor, Anju Seth, Hafsatu Wasagu Idris, Vijayalakshmi Bhatia, Junfen Fu, Gail Goldberg, Lars Sävendahl, Rajesh Khadgawat, Pawel Pludowski, Jane Maddock, Elina Hyppönen, Abiola Oduwole, Emma Frew, Magda Aguiar, Ted Tulchinsky, Gary Butler, Wolfgang Högler

Journal: J. Clin. Endocrinol. Metab.. 2016 Feb;101(2):394-415.

 

Vitamin D and calcium deficiencies are common worldwide, causing nutritional rickets and osteomalacia, which have a major impact on health, growth, and development of infants, children, and adolescents; the consequences can be lethal or can last into adulthood. The goals of this evidence-based ...

Last Updated: 4 Feb 2016

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Hypophosphatemic rickets: revealing novel control points for phosphate homeostasis.
 

Author(s): Kenneth E White, Julia M Hum, Michael J Econs

Journal: Curr Osteoporos Rep. 2014 Sep;12(3):252-62.

 

Rapid and somewhat surprising advances have recently been made toward understanding the molecular mechanisms causing heritable disorders of hypophosphatemia. The results of clinical, genetic, and translational studies have interwoven novel concepts underlying the endocrine control ...

Last Updated: 13 Aug 2014

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Coupling fibroblast growth factor 23 production and cleavage: iron deficiency, rickets, and kidney disease.
 

Author(s): Myles Wolf, Kenneth E White

Journal: Curr. Opin. Nephrol. Hypertens.. 2014 Jul;23(4):411-9.

 

High levels of fibroblast growth factor 23 (FGF23) cause the rare disorders of hypophosphatemic rickets and are a risk factor for cardiovascular disease and death in patients with chronic kidney disease (CKD). Despite major advances in understanding FGF23 biology, fundamental aspects ...

Last Updated: 6 Jun 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Iron Therapy for Autosomal Dominant Hypophosphatemic Rickets: A Pilot Project.
 

Status: Recruiting

Condition Summary: Autosomal Dominant Hypophosphatemic Rickets

 

Last Updated: 12 Apr 2016

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Vitamin D Status in Lower Extremity Joint Replacement Surgery Patients
 

Status: Not yet recruiting

Condition Summary: Hypovitaminosis D

 

Last Updated: 11 Dec 2014

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