Rhabdomyosarcoma alveolar

Common Name(s)

Rhabdomyosarcoma alveolar

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Rhabdomyosarcoma alveolar" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Rhabdomyosarcoma alveolar" returned 126 free, full-text research articles on human participants. First 3 results:

Crizotinib-induced antitumour activity in human alveolar rhabdomyosarcoma cells is not solely dependent on ALK and MET inhibition.
 

Author(s): Francesca Megiorni, Heather P McDowell, Simona Camero, Olga Mannarino, Simona Ceccarelli, Milena Paiano, Paul D Losty, Barry Pizer, Rajeev Shukla, Antonio Pizzuti, Anna Clerico, Carlo Dominici

Journal:

 

Rhabdomyosarcoma (RMS) is the most commonly diagnosed malignant soft tissue tumour in children and adolescents. Aberrant expression of Anaplastic Lymphoma Kinase (ALK) and MET gene has been implicated in the malignant progression of RMS, especially in the alveolar subtype. This observation ...

Last Updated: 8 Oct 2015

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DAX-1 Expression in Pediatric Rhabdomyosarcomas: Another Immunohistochemical Marker Useful in the Diagnosis of Translocation Positive Alveolar Rhabdomyosarcoma.
 

Author(s): Calogero Virgone, Enzo Lalli, Gianni Bisogno, Elena Lazzari, Josep Roma, Angelica Zin, Elena Poli, Giovanni Cecchetto, Patrizia Dall'Igna, Rita Alaggio

Journal:

 

The aim of this study was to investigate the expression of DAX-1 in a series of pediatric rhabdomyosarcomas (RMS) with known translocation and compare it to Ap2β, known to be selectively expressed in ARMS.

Last Updated: 14 Jul 2015

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Alveolar rhabdomyosarcoma of the anterior mediastinum with vessel invasion in a 4-month-old boy: a case report.
 

Author(s): Simon C Y Chow, Randolph H L Wong, Innes Y P Wan, Ka Fai To, Song Wan, Malcolm J Underwood, Calvin S H Ng

Journal:

 

Alveolar rhabdomyosarcomas of the mediastinum in children are rarely reported. Multimodality therapy including chemotherapy, surgery and radiotherapy make up the backbone of the treatment of childhood rhabdomyosarcomas. Complete resection whenever achievable is an important prognostic ...

Last Updated: 18 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Rhabdomyosarcoma alveolar" returned 4 free, full-text review articles on human participants. First 3 results:

Alveolar rhabdomyosarcoma with multiple distal metastases. A case report and review of literature.
 

Author(s): Debojyoti Sarkar, Sayantan Ray, Manjari Saha, Prantar Chakrabarti, Prantari Chakrabarti

Journal:

 

An 18-year-old boy, presented with a history of right hip pain with movement restriction and proptosis of right eye. There was severe anaemia, febrile neutropaenia and bleeding manifestations. CT scan of right orbit documented a retro orbital mass. MRI revealed a mass on right side ...

Last Updated: 5 Sep 2012

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New genetic tactics to model alveolar rhabdomyosarcoma in the mouse.
 

Author(s): Charles Keller, Mario R Capecchi

Journal: Cancer Res.. 2005 Sep;65(17):7530-2.

 

Using conditional knock-in and knock-out techniques, we designed a mouse model of the childhood muscle cancer alveolar rhabdomyosarcoma (ARMS) that is driven by the chromosomal translocation product, Pax3:Fkhr. Tumors that closely recapitulate the spectrum of molecular markers and ...

Last Updated: 5 Sep 2005

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Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma.
 

Author(s): F G Barr

Journal: Oncogene. 2001 Sep;20(40):5736-46.

 

The chromosomal translocations t(2;13)(q35;q14) and t(1;13)(p36;q14) are characteristic of alveolar rhabdomyosarcoma, a pediatric soft tissue cancer related to the striated muscle lineage. These translocations rearrange PAX3 and PAX7, members of the paired box transcription factor ...

Last Updated: 18 Oct 2001

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

CREATE: Cross-tumoral Phase 2 With Crizotinib
 

Status: Recruiting

Condition Summary: Locally Advanced and/or Metastatic Anaplastic Large Cell Lymphoma; Locally Advanced and/or Metastatic Inflammatory Myofibroblastic Tumor; Locally Advanced and/or Metastatic Papillary Renal Cell Carcinoma Type 1; Locally Advanced and/or Metastatic Alveolar Soft Part Sarcoma; Locally Advanced and/or Metastatic Clear Cell Sarcoma; Locally Advanced and/or Metastatic Alveolar Rhabdomyosarcoma

 

Last Updated: 16 Jul 2015

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Combination Chemotherapy and Irinotecan Hydrochloride or Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma
 

Status: Recruiting

Condition Summary: Alveolar Rhabdomyosarcoma; Botryoid-Type Embryonal Rhabdomyosarcoma; Embryonal Rhabdomyosarcoma; Rhabdomyosarcoma; Sclerosing Rhabdomyosarcoma; Spindle Cell Rhabdomyosarcoma; Untreated Childhood Rhabdomyosarcoma

 

Last Updated: 29 Jun 2016

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Studying Mechanisms of Radiation Therapy Resistance in Samples From Younger Patients With Rhabdomyosarcoma
 

Status: Recruiting

Condition Summary: Alveolar Childhood Rhabdomyosarcoma; Embryonal Childhood Rhabdomyosarcoma; Previously Treated Childhood Rhabdomyosarcoma; Previously Untreated Childhood Rhabdomyosarcoma; Recurrent Childhood Rhabdomyosarcoma

 

Last Updated: 13 May 2016

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