Rhabdomyosarcoma alveolar

Common Name(s)

Rhabdomyosarcoma alveolar

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Rhabdomyosarcoma alveolar" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Rhabdomyosarcoma alveolar" returned 100 free, full-text research articles on human participants. First 3 results:

PDGFRβ reverses EphB4 signaling in alveolar rhabdomyosarcoma.
 

Author(s): M Imran Aslam, Jinu Abraham, Atiya Mansoor, Brian J Druker, Jeffrey W Tyner, Charles Keller

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2014 Apr;111(17):6383-8.

 

Alveolar rhabdomyosarcoma (aRMS) is an aggressive myogenic childhood malignancy, not infrequently presenting as incurable metastatic disease. To identify therapeutic targets, we performed an unbiased tyrosine kinome RNA interference screen in primary cell cultures from a genetically ...

Last Updated: 30 Apr 2014

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Nasopharyngeal alveolar rhabdomyosarcoma expressing CD56: a mimicker of extranodal natural killer/T-cell lymphoma.
 

Author(s): Khin Than Win, Ming-Yuan Lee, Tran-Der Tan, Mung-pei Tsai, Armita Bahrami, Susana C Raimondi, Shih-Sung Chuang

Journal:

 

Alveolar rhabdomyosarcoma (ARMS) is remarkably rare in adults older than 45 years. Histologically, the tumor is composed of blue round cells with frequent expression of CD56 in addition to myogenic markers. Recent studies of ARMS have shown two specific recurrent translocations: PAX3-FKHR ...

Last Updated: 15 Jan 2014

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Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression.
 

Author(s): Lisa E S Crose, Kathleen A Galindo, Julie Grondin Kephart, Candy Chen, Julien Fitamant, Nabeel Bardeesy, Rex C Bentley, Rene L Galindo, Jen-Tsan Ashley Chi, Corinne M Linardic

Journal: J. Clin. Invest.. 2014 Jan;124(1):285-96.

 

Alveolar rhabdomyosarcoma (aRMS) is an aggressive sarcoma of skeletal muscle characterized by expression of the paired box 3-forkhead box protein O1 (PAX3-FOXO1) fusion oncogene. Despite its discovery nearly two decades ago, the mechanisms by which PAX3-FOXO1 drives tumor development ...

Last Updated: 2 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Rhabdomyosarcoma alveolar" returned 4 free, full-text review articles on human participants. First 3 results:

Alveolar rhabdomyosarcoma with multiple distal metastases. A case report and review of literature.
 

Author(s): Debojyoti Sarkar, Sayantan Ray, Manjari Saha, Prantar Chakrabarti, Prantari Chakrabarti

Journal:

 

An 18-year-old boy, presented with a history of right hip pain with movement restriction and proptosis of right eye. There was severe anaemia, febrile neutropaenia and bleeding manifestations. CT scan of right orbit documented a retro orbital mass. MRI revealed a mass on right side ...

Last Updated: 5 Sep 2012

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New genetic tactics to model alveolar rhabdomyosarcoma in the mouse.
 

Author(s): Charles Keller, Mario R Capecchi

Journal: Cancer Res.. 2005 Sep;65(17):7530-2.

 

Using conditional knock-in and knock-out techniques, we designed a mouse model of the childhood muscle cancer alveolar rhabdomyosarcoma (ARMS) that is driven by the chromosomal translocation product, Pax3:Fkhr. Tumors that closely recapitulate the spectrum of molecular markers and ...

Last Updated: 5 Sep 2005

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Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma.
 

Author(s): F G Barr

Journal: Oncogene. 2001 Sep;20(40):5736-46.

 

The chromosomal translocations t(2;13)(q35;q14) and t(1;13)(p36;q14) are characteristic of alveolar rhabdomyosarcoma, a pediatric soft tissue cancer related to the striated muscle lineage. These translocations rearrange PAX3 and PAX7, members of the paired box transcription factor ...

Last Updated: 18 Oct 2001

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

CREATE: Cross-tumoral Phase 2 With Crizotinib
 

Status: Recruiting

Condition Summary: Locally Advanced and/or Metastatic Anaplastic Large Cell Lymphoma; Locally Advanced and/or Metastatic Inflammatory Myofibroblastic Tumor; Locally Advanced and/or Metastatic Papillary Renal Cell Carcinoma Type 1; Locally Advanced and/or Metastatic Alveolar Soft Part Sarcoma; Locally Advanced and/or Metastatic Clear Cell Sarcoma; Locally Advanced and/or Metastatic Alveolar Rhabdomyosarcoma

 

Last Updated: 2 Jun 2014

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Studying Protein Expression in Tissue Samples From Younger Patients With Rhabdomyosarcoma
 

Status: Recruiting

Condition Summary: Alveolar Childhood Rhabdomyosarcoma; Embryonal Childhood Rhabdomyosarcoma; Previously Treated Childhood Rhabdomyosarcoma; Previously Untreated Childhood Rhabdomyosarcoma; Recurrent Childhood Rhabdomyosarcoma

 

Last Updated: 5 Aug 2014

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Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma
 

Status: Recruiting

Condition Summary: Adult Alveolar Soft-part Sarcoma; Adult Angiosarcoma; Adult Desmoplastic Small Round Cell Tumor; Adult Epithelioid Hemangioendothelioma; Adult Epithelioid Sarcoma; Adult Extraskeletal Chondrosarcoma; Adult Extraskeletal Osteosarcoma; Adult Fibrosarcoma; Adult Leiomyosarcoma; Adult Liposarcoma; Adult Malignant Fibrous Histiocytoma; Adult Malignant Hemangiopericytoma; Adult Malignant Mesenchymoma; Adult Neurofibrosarcoma; Adult Rhabdomyosarcoma; Adult Synovial Sarcoma; Childhood Alveolar Soft-part Sarcoma; Childhood Angiosarcoma; Childhood Desmoplastic Small Round Cell Tumor; Childhood Epithelioid Hemangioendothelioma; Childhood Epithelioid Sarcoma; Childhood Fibrosarcoma; Childhood Leiomyosarcoma; Childhood Liposarcoma; Childhood Malignant Hemangiopericytoma; Childhood Malignant Mesenchymoma; Childhood Neurofibrosarcoma; Childhood Synovial Sarcoma; Dermatofibrosarcoma Protuberans; Metastatic Childhood Soft Tissue Sarcoma; Nonmetastatic Childhood Soft Tissue Sarcoma; Recurrent Adult Soft Tissue Sarcoma; Recurrent Childhood Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma

 

Last Updated: 26 Jul 2014

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