Rhabdoid tumor

Common Name(s)

Rhabdoid tumor

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Rhabdoid tumor" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Rhabdoid tumor" returned 106 free, full-text research articles on human participants. First 3 results:

Phosphoproteomic analysis reveals Smarcb1 dependent EGFR signaling in Malignant Rhabdoid tumor cells.
 

Author(s): Jonatan Darr, Agnes Klochendler, Sara Isaac, Tamar Geiger, Tami Geiger, Amir Eden

Journal:

 

The SWI/SNF ATP dependent chromatin remodeling complex is a multi-subunit complex, conserved in eukaryotic evolution that facilitates nucleosomal re-positioning relative to the DNA sequence. In recent years the SWI/SNF complex has emerged to play a role in cancer development as various ...

Last Updated: 15 Sep 2015

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[About a rare case of atypical rhabdoid teratoid tumor of the central nervous system in a pregnant woman].
 

Author(s): Mohammed Afif, Jihane Khalil, Fadila Kouhen, Abdellah Aissa, Youssef Omour, Mustapha Elkabous, Hanan Elkacemi, Tayeb Kebdani, Noureddine Benjaafar

Journal:

 

Last Updated: 21 May 2015

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Primary atypical teratoid/rhabdoid tumor of the optic nerve: a rare entity in an exceptional location.
 

Author(s): Youssef Mahdi, Jinane Kharmoum, Amal Alouan, Hakima Elouarradi, Iman Elkhiyat, Mustapha Maher, Moulay Zahid Benchrif, Amina Kili, Rajae Daoudi, Nadia Cherradi

Journal:

 

Atypical teratoid/rhabdoid tumors are rare and highly malignant central nervous system tumors. They have no specific radiological features and often present several histological components that make a problem in differential diagnosis with medulloblastoma and primitive neuroectodermal ...

Last Updated: 2 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Rhabdoid tumor" returned 10 free, full-text review articles on human participants. First 3 results:

Atypical teratoid/rhabdoid tumor (AT/RT) arising from the acoustic nerve in a young adult: a case report and a review of literature.
 

Author(s): Xingfu Wang, Xueyong Liu, Zhixiong Lin, Yupeng Chen, Pengcheng Wang, Sheng Zhang

Journal: Medicine (Baltimore). 2015 Jan;94(4):e439.

 

Atypical teratoid/rhabdoid tumors (AT/RTs) are rare, highly malignant central nervous system tumors that predominantly occur in young children. A 22-year-old woman presented with a 4-year history of relapsing tinnitus and gradual hearing loss. Neuroimaging revealed an enhanced intrinsic ...

Last Updated: 30 Jan 2015

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Primary atypical teratoid/rhabdoid tumor of central nervous system in children: a clinicopathological analysis and review of literature in China.
 

Author(s): Min Yang, Xi Chen, Ning Wang, Kun Zhu, Ying-Zi Hu, Yun Zhao, Yan Shu, Man-Li Zhao, Wei-Zhong Gu, Hong-Feng Tang

Journal:

 

Atypical teratoid/rhabdoid tumor (AT/RT) is a very rare and highly malignant embryonal tumor in the central nervous system (CNS). Five patients (4 girls and 1 boy) with AT/RT were treated in our hospital. The clinical histories, symptoms, neuroimaging aspects, therapies, histological ...

Last Updated: 26 Jun 2014

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Mechanisms by which SMARCB1 loss drives rhabdoid tumor growth.
 

Author(s): Kimberly H Kim, Charles W M Roberts

Journal: Cancer Genet. 2014 Sep;207(9):365-72.

 

SMARCB1 (INI1/SNF5/BAF47), a core subunit of the SWI/SNF (BAF) chromatin-remodeling complex, is inactivated in the large majority of rhabdoid tumors, and germline heterozygous SMARCB1 mutations form the basis for rhabdoid predisposition syndrome. Mouse models validated Smarcb1 as ...

Last Updated: 9 Dec 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors
 

Status: Recruiting

Condition Summary: Malignant Rhabdoid Tumor; Atypical Teratoid Rhabdoid Tumor

 

Last Updated: 4 May 2016

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A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma
 

Status: Recruiting

Condition Summary: Malignant Rhabdoid Tumors (MRT); Rhabdoid Tumors of the Kidney (RTK); Atypical Teratoid Rhabdoid Tumors (ATRT); Selected Tumors With Rhabdoid Features; Synovial Sarcoma; INI1-negative Tumors; Malignant Rhabdoid Tumor of Ovary; Renal Medullary Carcinoma; Epithelioid Sarcoma

 

Last Updated: 22 Jul 2016

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A Phase 1 Study of the EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma
 

Status: Recruiting

Condition Summary: Rhabdoid Tumors; INI1-negative Tumors; Synovial Sarcoma; Malignant Rhabdoid Tumor of Ovary

 

Last Updated: 28 Jun 2016

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