Abdominal Aortic Aneurysm

Common Name(s)

Abdominal Aortic Aneurysm

Abdominal aortic aneurysms (AAAs) are aneurysms that occur in the part of the aorta that passes through the abdomen. They may occur at any age, but are most common in men between 50 and 80 years of age. Many people with an AAA have no symptoms, but some people have a pulsing sensation in the abdomen and/or pain in the back. If the aneurysm ruptures, it may cause deep, severe pain; nausea; vomiting; fast heart rate; clammy skin; and/or shock. About 20% of AAAs eventually rupture and are often fatal. The condition has multiple genetic and environmental risk factors, and may sometimes occur as part of an inherited syndrome. When more than one family member is affected, it may be considered "familial abdominal aortic aneurysm." Treatment depends on the size of the aneurysm and may include blood pressure medications, or surgery to repair the aneurysm.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Abdominal Aortic Aneurysm" for support, advocacy or research.

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Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

Last Updated: 22 Jan 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Abdominal Aortic Aneurysm" for support, advocacy or research.

Logo
Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

http://www.marfan.ca

Last Updated: 22 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Abdominal Aortic Aneurysm" returned 1126 free, full-text research articles on human participants. First 3 results:

Long-term outcome of ruptured abdominal aortic aneurysm: impact of treatment and age.
 

Author(s): Jelle W Raats, Hans C Flu, Gwan H Ho, Eelco J Veen, Louwerens D Vos, Ewout W Steyerberg, Lijckle van der Laan

Journal:

 

Despite advances in operative repair, ruptured abdominal aortic aneurysm (rAAA) remains associated with high mortality and morbidity rates, especially in elderly patients. The purpose of this study was to evaluate the outcomes of emergency endovascular aneurysm repair (eEVAR), conventional ...

Last Updated: 24 Oct 2014

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Improving the efficiency of abdominal aortic aneurysm wall stress computations.
 

Author(s): Jaime E Zelaya, Sevan Goenezen, Phong T Dargon, Amir-Farzin Azarbal, Sandra Rugonyi

Journal:

 

An abdominal aortic aneurysm is a pathological dilation of the abdominal aorta, which carries a high mortality rate if ruptured. The most commonly used surrogate marker of rupture risk is the maximal transverse diameter of the aneurysm. More recent studies suggest that wall stress ...

Last Updated: 10 Jul 2014

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Early and delayed rupture after endovascular abdominal aortic aneurysm repair in a 10-year multicenter registry.
 

Author(s): Leah Candell, Lue-Yen Tucker, Philip Goodney, Joy Walker, Steven Okuhn, Bradley Hill, Robert Chang

Journal: J. Vasc. Surg.. 2014 Nov;60(5):1146-52.

 

Rupture after abdominal endovascular aortic aneurysm repair (EVAR) is a function of graft maintenance of the seal and fixation. We describe our 10-year experience with rupture after EVAR.

Last Updated: 2 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Abdominal Aortic Aneurysm" returned 118 free, full-text review articles on human participants. First 3 results:

Novel biomarkers of abdominal aortic aneurysm disease: identifying gaps and dispelling misperceptions.
 

Author(s): Demetrios Moris, Eleftherios Mantonakis, Efthymios Avgerinos, Marinos Makris, Chris Bakoyiannis, Emmanuel Pikoulis, Sotirios Georgopoulos

Journal: Biomed Res Int. 2014 ;2014():925840.

 

Abdominal aortic aneurysm (AAA) is a prevalent and potentially life-threatening disease. Early detection by screening programs and subsequent surveillance has been shown to be effective at reducing the risk of mortality due to aneurysm rupture. The aim of this review is to summarize ...

Last Updated: 26 Jun 2014

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Enhanced recovery after elective open surgical repair of abdominal aortic aneurysm: a complementary overview through a pooled analysis of proportions from case series studies.
 

Author(s): Sanderland J T Gurgel, Regina El Dib, Paulo do Nascimento

Journal:

 

To evaluate the efficacy and safety of enhanced recovery after surgery (ERAS) programs in elective open surgical repair (OSR) of abdominal aortic aneurysm (AAA).

Last Updated: 3 Jun 2014

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Editor's Choice - Endovascular aneurysm repair versus open repair for patients with a ruptured abdominal aortic aneurysm: a systematic review and meta-analysis of short-term survival.
 

Author(s): S C van Beek, A P Conijn, M J Koelemay, R Balm

Journal: Eur J Vasc Endovasc Surg. 2014 Jun;47(6):593-602.

 

There is clinical equipoise between open (OR) and endovascular aneurysm repair (EVAR) for the best treatment of ruptured abdominal aortic aneurysm (RAAA).

Last Updated: 26 May 2014

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Cyclosporine A in Patients With Small Diameter Abdominal Aortic Aneurysms
 

Status: Recruiting

Condition Summary: Abdominal Aortic Aneurysm,; Small Abdominal Aortic Aneurysm

 

Last Updated: 25 Aug 2014

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Study of the Glycocalyx in Abdominal Aortic Aneurysm
 

Status: Recruiting

Condition Summary: Abdominal Aortic Aneurism; Surgery; Ischemic Reperfusion Injury

 

Last Updated: 16 Apr 2013

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ACZ885 for the Treatment of Abdominal Aortic Aneurysm
 

Status: Recruiting

Condition Summary: Abdominal Aortic Aneurysm (AAA)

 

Last Updated: 22 Sep 2014

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