Abdominal aortic aneurysm

Common Name(s)

Abdominal aortic aneurysm

An abdominal aortic aneurysm (AAA) is when the lower part of the aorta becomes enlarged, like a balloon. The aorta is the largest artery in the body. It carries blood from the heart down along the backbone where it splits into many smaller arteries that bring blood to all of the organs. Aneurysm is a general term that describes an enlargement of any blood vessel in the body. Aneurysms usually develop slowly over time and may not cause problems until they become so enlarged that they can rupture.

Smaller AAAs generally do not cause symptoms. Larger AAAs can cause symptoms such as a pulsating feeling near the belly button, deep and constant abdominal pain, or back pain. Rupture of an aortic aneurysm is a medical emergency. If an aortic aneurysm ruptures, symptoms include vomiting, intense pain, excessive sweating, a drop in blood pressure, fainting, and shortness of breath.

AAAs can be caused by stiffening of the artery walls due to plaque build up (atherosclerosis), infection of the aorta, or connective tissue diseases. Risk factors for the development of AAAs are increased in individuals who smoke, are male, or have a family history of aneurysms.

A doctor can perform many tests to diagnose this condition. Possible tests include imaging by abdominal ultrasound, chest X-ray, and MRI. Treatment options will vary depending on the size of the aneurysm. For smaller aneurysms, it may be better to wait and watch before seeking surgery. For larger aneurysms that are at risk of rupturing, surgery is usually the best treatment. Talk to your doctor about which of the current treatment options is right for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Abdominal aortic aneurysm" for support, advocacy or research.

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Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

Last Updated: 22 Jan 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Abdominal aortic aneurysm" for support, advocacy or research.

Logo
Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

http://www.marfan.ca

Last Updated: 22 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Abdominal aortic aneurysm" returned 1857 free, full-text research articles on human participants. First 3 results:

Marfan syndrome combined with huge abdominal aortic aneurysm size of 20 × 11 cm: A case report of surgical approach.
 

Author(s): Tian-Hua Zhang, De-Cai Chi, Wei-Liang Jiang, Shuai Qiang

Journal: Medicine (Baltimore). 2018 Sep;97(37):e09398.

 

Abdominal aortic aneurysm is one of the most common aneurisms. Patients presenting with secondary back pain should be given prompt medical attention. Herein, a rare case of a giant abdominal aortic aneurysm that was successfully treated with surgery is described.

Last Updated: 31 Dec 1969

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Proprotein Convertase Subtilisin/Kexin Type 9 Is Associated with Degenerating Adipocytes in Abdominal Aortic Aneurysm.
 

Author(s): Hiroki Tanaka, Kazunori Inuzuka, Yasunori Iida, Hideyuki Shimizu, Naoki Unno, Tetsumei Urano

Journal: J Oleo Sci. 2018 Oct;67(10):1355-1360.

 

Abdominal aortic aneurysm (AAA) is a common disease among the elderly. Recently, proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors have been indicated as useful therapeutic tools for the treatment of cardiovascular diseases. The aim of this study was to elucidate the ...

Last Updated: 31 Dec 1969

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Novel surgical treatment of abdominal aortic aneurysm complicated with primary aorto-colonic fistula: A case report.
 

Author(s): Maoxun Huang, Hulin Piao, Yong Wang, Weitie Wang, Shibo Wei, Chulong Xie, Kexiang Liu

Journal: Medicine (Baltimore). 2018 Aug;97(33):e11890.

 

Primary aorto-colonic fistula is a rare complication of an abdominal aortic aneurysm. Without surgical treatment, the associated mortality rate is 100%. Even if patients receive timely surgical treatment, they may still die of complications such as infection.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Abdominal aortic aneurysm" returned 186 free, full-text review articles on human participants. First 3 results:

Modulation of Immune-Inflammatory Responses in Abdominal Aortic Aneurysm: Emerging Molecular Targets.
 

Author(s): Hanrong Li, Shuling Bai, Qiang Ao, Xiaohong Wang, Xiaohong Tian, Xiang Li, Hao Tong, Weijian Hou, Jun Fan

Journal:

 

Abdominal aortic aneurysm (AAA), a deadly vascular disease in human, is a chronic degenerative process of the abdominal aorta. In this process, inflammatory responses and immune system work efficiently by inflammatory cell attraction, proinflammatory factor secretion and subsequently ...

Last Updated: 31 Dec 1969

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[Ruptured abdominal aortic aneurysm].
 

Author(s): V Tchana-Sato, N Sakalihasan, J O Defraigne

Journal: Rev Med Liege. 2018 May;73(5-6):296-299.

 

Ruptured abdominal aortic aneurysm is a cardiovascular emergency associated with a 30 day mortality as high as 70 %. However, recent progresses in the management of these patients have improved the results. From a surgical point of view, endovascular methods such as balloon occlusion ...

Last Updated: 31 Dec 1969

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Endothelium as a Potential Target for Treatment of Abdominal Aortic Aneurysm.
 

Author(s): Jingyuan Sun, Hongping Deng, Zhen Zhou, Xiaoxing Xiong, Ling Gao

Journal:

 

Abdominal aortic aneurysm (AAA) was previously ascribed to weaken defective medial arterial/adventitial layers, for example, smooth muscle/fibroblast cells. Therefore, besides surgical repair, medications targeting the medial layer to strengthen the aortic wall are the most feasible ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Efficacy Study of Abdominal Aortic Aneurysm Stent Graft System
 

Status: Not yet recruiting

Condition Summary: Abdominal Aortic Aneurysm

 

Last Updated: 26 Sep 2018

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Biomarker Profiling in Abdominal Aortic Aneurysm Patients
 

Status: Recruiting

Condition Summary: Abdominal Aortic Aneurysm

 

Last Updated: 11 Oct 2018

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