Abdominal aortic aneurysm

Common Name(s)

Abdominal aortic aneurysm

An abdominal aortic aneurysm (AAA) is when the lower part of the aorta becomes enlarged, like a balloon. The aorta is the largest artery in the body. It carries blood from the heart down along the backbone where it splits into many smaller arteries that bring blood to all of the organs. Aneurysm is a general term that describes an enlargement of any blood vessel in the body. Aneurysms usually develop slowly over time and may not cause problems until they become so enlarged that they can rupture.

Smaller AAAs generally do not cause symptoms. Larger AAAs can cause symptoms such as a pulsating feeling near the belly button, deep and constant abdominal pain, or back pain. Rupture of an aortic aneurysm is a medical emergency. If an aortic aneurysm ruptures, symptoms include vomiting, intense pain, excessive sweating, a drop in blood pressure, fainting, and shortness of breath.

AAAs can be caused by stiffening of the artery walls due to plaque build up (atherosclerosis), infection of the aorta, or connective tissue diseases. Risk factors for the development of AAAs are increased in individuals who smoke, are male, or have a family history of aneurysms.

A doctor can perform many tests to diagnose this condition. Possible tests include imaging by abdominal ultrasound, chest X-ray, and MRI. Treatment options will vary depending on the size of the aneurysm. For smaller aneurysms, it may be better to wait and watch before seeking surgery. For larger aneurysms that are at risk of rupturing, surgery is usually the best treatment. Talk to your doctor about which of the current treatment options is right for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Abdominal aortic aneurysm" for support, advocacy or research.

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Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

Last Updated: 22 Jan 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Abdominal aortic aneurysm" for support, advocacy or research.

Logo
Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

http://www.marfan.ca

Last Updated: 22 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Abdominal aortic aneurysm" returned 1631 free, full-text research articles on human participants. First 3 results:

[Change of Serum Angiopoietin-related Growth Factor in Patients with Abdominal Aortic Aneurysm and Its Clinical Significance].
 

Author(s): Hao Nie, Yue Liang, Hua-liang Ren, Yue-wei Wang, Cui Tian, Hui-hua Li, Yue-hong Zheng

Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2016 Apr;38(2):150-4.

 

To investigate the changes and value of plasma angiopoietin-related growth factor (AGF) in patients with abdominal aortic aneurysm (AAA).

Last Updated: 16 May 2016

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Results of Open and Endovascular Abdominal Aortic Aneurysm Repair According to the E-PASS Score.
 

Author(s): Fábio Hüsemann Menezes, Bárbara Ferrarezi, Moisés Amâncio de Souza, Susyanne Lavor Cosme, Giovani José Dal Poggetto Molinari

Journal: Braz J Cardiovasc Surg. 2016 Feb;31(1):22-30.

 

Endovascular repair (EVAR) of abdominal aortic aneurysm has become the standard of care due to a lower 30-day mortality, a lower morbidity, shorter hospital stay and a quicker recovery. The role of open repair (OR) and to whom this type of operation should be offered is subject to discussion.

Last Updated: 14 Apr 2016

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Matricellular protein CCN3 mitigates abdominal aortic aneurysm.
 

Author(s): Chao Zhang, Dustin van der Voort, Hong Shi, Rongli Zhang, Yulan Qing, Shuichi Hiraoka, Minoru Takemoto, Koutaro Yokote, Joseph V Moxon, Paul Norman, Laure Rittié, Helena Kuivaniemi, G Brandon Atkins, Stanton L Gerson, Guo-Ping Shi, Jonathan Golledge, Nianguo Dong, Bernard Perbal, Domenick A Prosdocimo, Zhiyong Lin

Journal: J. Clin. Invest.. 2016 Apr;126(4):1282-99.

 

Abdominal aortic aneurysm (AAA) is a major cause of morbidity and mortality; however, the mechanisms that are involved in disease initiation and progression are incompletely understood. Extracellular matrix proteins play an integral role in modulating vascular homeostasis in health ...

Last Updated: 2 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Abdominal aortic aneurysm" returned 156 free, full-text review articles on human participants. First 3 results:

Endovascular vs. Open Repair for Ruptured Abdominal Aortic Aneurysm.
 

Author(s): Nikolaos Patelis, Demetrios Moris, Georgios Karaolanis, Sotiris Georgopoulos

Journal:

 

Patients presenting with ruptured abdominal aortic aneurysms are most often treated with open repair despite the fact that endovascular aneurysm repair is a less invasive and widely accepted method with clear benefits for elective aortic aneurysm patients. A debate exists regarding ...

Last Updated: 19 Apr 2016

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The Effect of Perioperative Ischemia and Reperfusion on Multiorgan Dysfunction following Abdominal Aortic Aneurysm Repair.
 

Author(s): Konstantina Katseni, Athanasios Chalkias, Thomas Kotsis, Nikolaos Dafnios, Vassilis Arapoglou, Georgios Kaparos, Emmanuel Logothetis, Nicoletta Iacovidou, Eleni Karvouni, Konstantinos Katsenis

Journal: Biomed Res Int. 2015 ;2015():598980.

 

Abdominal aortic aneurysms (AAAs) are relatively common and are potentially life-threatening medical problems. The aim of this review is to provide an overview of the effect of I/R injury on multiorgan failure following AAA repair. The PubMed, CINAHL, EMBASE, Medline, Cochrane Review, ...

Last Updated: 22 Jan 2016

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Novel Molecular Imaging Approaches to Abdominal Aortic Aneurysm Risk Stratification.
 

Author(s): Jakub Toczek, Judith L Meadows, Mehran M Sadeghi

Journal: Circ Cardiovasc Imaging. 2016 Jan;9(1):e003023.

 

Selection of patients for abdominal aortic aneurysm repair is currently based on aneurysm size, growth rate, and symptoms. Molecular imaging of biological processes associated with aneurysm growth and rupture, for example, inflammation and matrix remodeling, could improve patient ...

Last Updated: 14 Jan 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Clinical Study of the Treovance Stent-Graft for Patients With Abdominal Aortic Aneurysms
 

Status: Recruiting

Condition Summary: Abdominal Aortic Aneurysm (AAA)

 

Last Updated: 21 Aug 2015

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Sodium Fluoride Imaging of Abdominal Aortic Aneurysms
 

Status: Recruiting

Condition Summary: Abdominal Aortic Aneurysm

 

Last Updated: 25 Oct 2016

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