Abdominal Aortic Aneurysm

Common Name(s)

Abdominal Aortic Aneurysm

Abdominal aortic aneurysms (AAAs) are aneurysms that occur in the part of the aorta that passes through the abdomen. They may occur at any age, but are most common in men between 50 and 80 years of age. Many people with an AAA have no symptoms, but some people have a pulsing sensation in the abdomen and/or pain in the back. If the aneurysm ruptures, it may cause deep, severe pain; nausea; vomiting; fast heart rate; clammy skin; and/or shock. About 20% of AAAs eventually rupture and are often fatal. The condition has multiple genetic and environmental risk factors, and may sometimes occur as part of an inherited syndrome. When more than one family member is affected, it may be considered "familial abdominal aortic aneurysm." Treatment depends on the size of the aneurysm and may include blood pressure medications, or surgery to repair the aneurysm.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Abdominal Aortic Aneurysm" for support, advocacy or research.

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Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

Last Updated: 22 Jan 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Abdominal Aortic Aneurysm" for support, advocacy or research.

Logo
Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

http://www.marfan.ca

Last Updated: 22 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Abdominal Aortic Aneurysm" returned 1335 free, full-text research articles on human participants. First 3 results:

High incidence of periodontitis in Japanese patients with abdominal aortic aneurysm.
 

Author(s): Jun-Ichi Suzuki, Norio Aoyama, Mieko Aoki, Yuko Tada, Kouji Wakayama, Hiroshi Akazawa, Kunihiro Shigematsu, Katsuyuki Hoshina, Yuichi Izumi, Issei Komuro, Tetsuro Miyata, Yasunobu Hirata, Mitsuaki Isobe

Journal: Int Heart J. 2014 ;55(3):268-70.

 

Periodontitis is known to be a risk factor for abdominal aortic aneurysm (AAA). However, the influence of periodontitis on AAA in Japanese patients has not yet been elucidated. The aim of this clinical investigation was to assess the relationship between periodontal bacterial burden ...

Last Updated: 26 May 2014

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Aneurysmal lesions of patients with abdominal aortic aneurysm contain clonally expanded T cells.
 

Author(s): Song Lu, John V White, Wan Lu Lin, Xiaoying Zhang, Charalambos Solomides, Kyle Evans, Nectaria Ntaoula, Ifeyinwa Nwaneshiudu, John Gaughan, Dimitri S Monos, Emilia L Oleszak, Chris D Platsoucas

Journal: J. Immunol.. 2014 May;192(10):4897-912.

 

Abdominal aortic aneurysm (AAA) is a common disease with often life-threatening consequences. This vascular disorder is responsible for 1-2% of all deaths in men aged 65 years or older. Autoimmunity may be responsible for the pathogenesis of AAA. Although it is well documented that ...

Last Updated: 5 May 2014

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Endovascular or open repair strategy for ruptured abdominal aortic aneurysm: 30 day outcomes from IMPROVE randomised trial.
 

Author(s): , Janet T Powell, Michael J Sweeting, Matthew M Thompson, Ray Ashleigh, Rachel Bell, Manuel Gomes, Roger M Greenhalgh, Richard Grieve, Francine Heatley, Robert J Hinchliffe, Simon G Thompson, Pinar Ulug

Journal:

 

To assess whether a strategy of endovascular repair (if aortic morphology is suitable, open repair if not) versus open repair reduces early mortality for patients with suspected ruptured abdominal aortic aneurysm.

Last Updated: 14 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Abdominal Aortic Aneurysm" returned 121 free, full-text review articles on human participants. First 3 results:

Current status of medical treatment for abdominal aortic aneurysm.
 

Author(s): Koji Kurosawa, Jon S Matsumura, Dai Yamanouchi

Journal: Circ. J.. 2013 ;77(12):2860-6.

 

Although cardiovascular disease is widely recognized as the leading cause of death, a lesser known fact is that aortic aneurysm is the 15th leading cause of death over the age of 65 years in the USA. The golden standard of the treatments are invasive interventions either with open ...

Last Updated: 25 Nov 2013

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Exome sequencing reveals new insights into the progression of abdominal aortic aneurysm.
 

Author(s): S-M Wang, G Zhao, L Peng, W Yang

Journal: Eur Rev Med Pharmacol Sci. 2013 Sep;17(17):2401-9.

 

Abdominal aortic aneurysm (AAA) is a multi-factorial disease and its underlying pathogenesis remains poorly understood.

Last Updated: 25 Sep 2013

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The role of geometric and biomechanical factors in abdominal aortic aneurysm rupture risk assessment.
 

Author(s): Samarth S Raut, Santanu Chandra, Judy Shum, Ender A Finol

Journal: Ann Biomed Eng. 2013 Jul;41(7):1459-77.

 

The current clinical management of abdominal aortic aneurysm (AAA) disease is based to a great extent on measuring the aneurysm maximum diameter to decide when timely intervention is required. Decades of clinical evidence show that aneurysm diameter is positively associated with the ...

Last Updated: 10 Jun 2013

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Reduction of Myocardial Infarction by Preconditioning in Patients With Ruptured Abdominal Aortic Aneurysm
 

Status: Recruiting

Condition Summary: Abdominal Aortic Aneurysm

 

Last Updated: 30 Jan 2012

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Screening for Abdominal Aortic Aneurysm and Abdominal Aortic Atherosclerosis by Hand-Held Ultrasonography
 

Status: Recruiting

Condition Summary: Hypertension; Abdominal Aortic Aneurysm; Atheromatosis

 

Last Updated: 5 Sep 2012

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Curcumin to Prevent Complications After Elective Abdominal Aortic Aneurysm (AAA) Repair
 

Status: Recruiting

Condition Summary: Acute Kidney Injury; Abdominal Aortic Aneurysm

 

Last Updated: 21 Dec 2012

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