Retroperitoneal fibrosis

Common Name(s)

Retroperitoneal fibrosis, Ormond's Disease

Retroperitoneal fibrosis is a slowly progressive disorder in which the tubes that carry urine from the kidneys to the bladder (ureters) and other abdominal organs are blocked by a fibrous mass and inflammation in the back of the abdomen. The disorder may cause chronic unilateral obstructive uropathy or chronic bilateral obstructive uropathy. Risk factors for retroperitoneal fibrosis include asbestos exposure, smoking, tumor, infection, trauma, radiotherapy, surgery, and use of certain drugs.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Retroperitoneal fibrosis" for support, advocacy or research.

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Retroperitoneal Fibrosis World Support

We offer both a warm and comforting welcome and an unrivaled learning experience to build self awareness of RF. We welcome all patients, caregivers, family, friends, and interested medical professionals. This forum is for each member to offer others moral support, friendship, and opinions and advice based on our personal experiences with RF This group includes access to unsurpassed resources of professional papers, case histories, files, relevant links, a member recommended doctor database, information tables, and much more; to allow meaningful, valued exchanges and social interaction.

Last Updated: 29 Mar 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Retroperitoneal fibrosis" for support, advocacy or research.

Logo
Retroperitoneal Fibrosis World Support

We offer both a warm and comforting welcome and an unrivaled learning experience to build self awareness of RF. We welcome all patients, caregivers, family, friends, and interested medical professionals. This forum is for each member to offer others moral support, friendship, and opinions and advice based on our personal experiences with RF This group includes access to unsurpassed resources of professional papers, case histories, files, relevant links, a member recommended doctor database, information tables, and much more; to allow meaningful, valued exchanges and social interaction.

https://groups.yahoo.com/neo/groups/retroperitoneal_fibrosisworldsuppo ...

Last Updated: 29 Mar 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Retroperitoneal fibrosis" returned 167 free, full-text research articles on human participants. First 3 results:

[Retroperitoneal fibrosis associated with malignancies: report of eight cases].
 

Author(s): Jorge Vega, Alejandro Ceriani, Daniela Jensen

Journal: Rev Med Chil. 2014 Jun;142(6):791-8.

 

Retroperitoneal fibrosis (RPF) is uncommon. Eight percent of cases are associated with malignancies. The pathogenesis of cancer related RPF (MRPF) is unknown. It may be originated from a desmoplastic reaction of the retroperitoneum to the presence of malignant cells, to the action ...

Last Updated: 20 Oct 2014

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Chronic periaortitis (retroperitoneal fibrosis) concurrent with giant cell arteritis: a case report.
 

Author(s): Ioannis Protopsaltis, Athanasios Sotiropoulos, Argyrios Foteinos, Kassiani Manoloudaki, Kiriaki Boki, Garifallia Linardaki, Athanasia Papazafiropoulou, Stavros Antonopoulos

Journal:

 

Giant cell arteritis is the most common form of large-vessel vasculitides. However, it is probable that extracranial involvement is underdiagnosed in patients with classical giant cell arteritis. In the recent literature most cases of giant cell arteritis have been described in conjunction ...

Last Updated: 26 Jun 2014

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[IgG4-related prostatitis associated with retroperitoneal fibrosis: a case report].
 

Author(s): Yasushi Nakai, Yoriaki Kagebayashi, Yoshihiro Matsumoto, Shinji Fukui, Yoshikatsu Kim, Shuhei Yoshimoto, Naoki Maruyama, Shoji Samma

Journal: Hinyokika Kiyo. 2013 Dec;59(12):781-4.

 

A 70-year-old male was referred to our hospital because of an abnormally high prostate specific antigen (PSA) level (4.4 ng/ml) associated with lower urinary tract symptoms. Needle biopsy of the prostate did not reveal any malignant tissue. Four months later, the patient presented ...

Last Updated: 14 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Retroperitoneal fibrosis" returned 15 free, full-text review articles on human participants. First 3 results:

Clinical features of 10 patients with IgG4-related retroperitoneal fibrosis.
 

Author(s): Kazuro Chiba, Terumi Kamisawa, Taku Tabata, Seiichi Hara, Sawako Kuruma, Takashi Fujiwara, Go Kuwata, Hideto Egashira, Koichi Koizumi, Satomi Koizumi, Junko Fujiwara, Takeo Arakawa, Kumiko Momma, Keigo Setoguchi, Mitsuru Shinohara

Journal: Intern. Med.. 2013 ;52(14):1545-51.

 

To elucidate the clinical characteristics of IgG4-related retroperitoneal fibrosis (RF).

Last Updated: 16 Jul 2013

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Retroperitoneal fibrosis associated with immunoglobulin G4-related disease.
 

Author(s): Nao Fujimori, Tetsuhide Ito, Hisato Igarashi, Takamasa Oono, Taichi Nakamura, Yusuke Niina, Masayuki Hijioka, Lingaku Lee, Masahiko Uchida, Ryoichi Takayanagi

Journal: World J. Gastroenterol.. 2013 Jan;19(1):35-41.

 

Retroperitoneal fibrosis is a rare disease characterized by the development of inflammation and fibrosis in the soft tissues of the retroperitoneum and other abdominal organs. Retroperitoneal fibrosis can be of 2 types: idiopathic and secondary. The recently advocated concept and ...

Last Updated: 17 Jan 2013

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Proteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA) positive IgG4-related retroperitoneal fibrosis: utility of PET-CT with 18F-fluorodeoxy glucose (FDG).
 

Author(s): Shie Kotani, Ryo Wakamatsu, Ayano Itoh, Kanyu Miyamoto, Masabumi Yoshino, Kazuhisa Takami, Satoshi Ishihara, Naoto Miura, Shogo Banno, Hirokazu Imai

Journal: Intern. Med.. 2012 ;51(7):755-8.

 

A 55-year-old man showed a serum creatinine level of 1.51 mg/dL, CRP of 0.79 mg/dL, and proteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA) of 43.9 EU (normal range: below 10). The serum levels and ratios of IgG1, IgG2, IgG3, and IgG4 to total IgG were 1,570 mg/dL (49%), ...

Last Updated: 2 Apr 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Methotrexate as a Steroid-sparing Agent in Idiopathic Retroperitoneal Fibrosis: a Randomised, Multicenter Trial
 

Status: Recruiting

Condition Summary: Idiopathic Retroperitoneal Fibrosis; Perianeurysmal Retroperitoneal Fibrosis; Chronic Periaortitis

 

Last Updated: 12 Nov 2010

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