Asplenia

Common Name(s)

Asplenia

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Asplenia" for support, advocacy or research.

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Heterotaxy Foundation

The Heterotaxy Foundation is a non-profit organization created to raise funds for research and promote awareness of a rare disease called Heterotaxy Syndrome.

Last Updated: 12 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Asplenia" for support, advocacy or research.

Logo
Heterotaxy Foundation

The Heterotaxy Foundation is a non-profit organization created to raise funds for research and promote awareness of a rare disease called Heterotaxy Syndrome.

http://www.heterotaxy.org

Last Updated: 12 Feb 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Asplenia" returned 39 free, full-text research articles on human participants. First 3 results:

Dextrocardia and asplenia in situs inversus totalis in a baby: a case report.
 

Author(s): Abnish Kumar, Manoj Kumar Singh, Neeraj Yadav

Journal:

 

Situs inversus with dextrocardia is the complete inversion of position of the thoracic and abdominal viscera. It may be isolated or associated with malformations, especially cardiac and/or alimentary. It may be discovered in infancy because of associated anomalies but often remains ...

Last Updated: 17 Dec 2014

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Perinatal and infant outcomes of prenatal diagnosis of heterotaxy syndrome (asplenia and polysplenia).
 

Author(s): Maria C Escobar-Diaz, Kevin Friedman, Yishay Salem, Gerald R Marx, Brian T Kalish, Terra Lafranchi, Rahul H Rathod, Sitaram Emani, Tal Geva, Wayne Tworetzky

Journal: Am. J. Cardiol.. 2014 Aug;114(4):612-7.

 

Patients with heterotaxy syndrome (HS) have a range of anomalies and outcomes. There are limited data on perinatal outcomes after prenatal diagnosis. To determine the factors influencing perinatal and infant outcomes, we analyzed prenatal and postnatal variables in fetuses with HS ...

Last Updated: 4 Aug 2014

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ZEB2, a new candidate gene for asplenia.
 

Author(s): Linda Pons, Sophie Dupuis-Girod, Marie-Pierre Cordier, Patrick Edery, Massimiliano Rossi

Journal:

 

Last Updated: 14 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Asplenia" returned 3 free, full-text review articles on human participants. First 3 results:

[Children with asplenia or hyposplenia: Preventing overwhelming post splenectomy infection].
 

Author(s): Fernanda Cofré, José Cofré

Journal: Rev Chilena Infectol. 2014 Feb;31(1):66-72.

 

The spleen's ability to prevent overwhelming post-splenectomy infection (OPSI) is mainly given by its capacity to filter and phagocyte bacterial elements from the blood, remove foreign elements from it, and the early production of opsonins. The anatomic absence of the spleen is usually ...

Last Updated: 17 Apr 2014

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[Congenital asplenia and pneumococcal purpura fulminans in a pediatric patient: case report with pathological findings and review].
 

Author(s): Katalina Bertrán S, Alejandro Donoso F, Pablo Cruces R, Franco Díaz R, Daniela Arriagada S

Journal: Rev Chilena Infectol. 2009 Feb;26(1):55-9.

 

Absent or defective splenic function is associated with a high risk of fulminant bacterial infections, especially due to encapsulated bacteria. Not knowing this condition may delay medical treatment. Streptococcus pneumoniae is the leading cause of sepsis in these patients. Asplenic ...

Last Updated: 7 Apr 2009

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Congenital asplenia and group B streptococcus sepsis in the adult: case report and review of the literature.
 

Author(s): Kumaran Thiruppathy, Antonio Privitera, Kapila Jain, Sanjay Gupta

Journal: FEMS Immunol. Med. Microbiol.. 2008 Aug;53(3):437-9.

 

Asplenia is associated with an increased incidence of fatal and life-threatening sepsis caused by encapsulated pathogens. Isolated congenital asplenia is a very rare condition, with only 33 cases reported in the literature. The authors report another case of this condition complicated ...

Last Updated: 4 Sep 2008

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 1 Dec 2014

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Molecular Genetics of Heterotaxy and Related Congenital Heart Defects
 

Status: Recruiting

Condition Summary: Heterotaxy Syndrome; Congenital Heart Defects

 

Last Updated: 30 Apr 2015

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