Aspergillosis

Common Name(s)

Aspergillosis

Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aspergillosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aspergillosis" returned 984 free, full-text research articles on human participants. First 3 results:

Evaluation of a commercial quantitative Aspergillus fumigatus-specific IgM assay for the diagnosis of invasive pulmonary aspergillosis.
 

Author(s): Yake Yao, Hua Zhou, Yihong Shen, Qing Yang, Jian Ye, Guohua Lu, Yiqi Fu, Haiyan Lou, Yunsong Yu, Jianying Zhou

Journal: Medicine (Baltimore). 2017 Dec;96(51):e9436.

 

Invasive pulmonary aspergillosis (IPA) is a common fungal infection with high mortality rates in immunocompromised patients. Early diagnosis of IPA is still challenging because of its nonspecific clinical symptoms and radiological presentations.To evaluate the clinical value of a ...

Last Updated: 31 Dec 1969

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Efficacy and safety of micafungin for the treatment of patients with proven or probable invasive aspergillosis: A non-comparative, multicenter, phase IV, open-label study.
 

Author(s): Yu Ji, Yongping Song, Fang Zhou, Ting Liu, Ming Jiang, Xielan Zhao, Xiaojun Huang

Journal: Medicine (Baltimore). 2017 Dec;96(52):e9443.

 

Few studies have assessed the efficacy and safety of micafungin in patients with proven or probable invasive aspergillosis (IA). This was the aim of the current study, which was conducted in 22 hospitals in China, where micafungin was approved for treatment of IA in 2006.

Last Updated: 31 Dec 1969

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Infant Central Nervous System Aspergillosis with First-episode of Intracranial Hemorrhage: A case report.
 

Author(s): Yang Wang, Deyuan Li, Lina Qiao, Fumin Zhao

Journal: Medicine (Baltimore). 2017 Nov;96(47):e8893.

 

Central nervous system (CNS) aspergillosis has the characteristics of multifocality, polymorphism, and coexistence of pathological types, and missed diagnosis and misdiagnosis frequently occur at the initial stage. The thesis reports a rare case of infant infection of CNS aspergillosis ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aspergillosis" returned 125 free, full-text review articles on human participants. First 3 results:

Novel cutting-edge metabolite-based diagnostic tools for aspergillosis.
 

Author(s): Masha G Savelieff, Lucia Pappalardo

Journal:

 

Last Updated: 31 Dec 1969

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Simultaneous primary invasive cutaneous aspergillosis in two preterm twins: case report and review of the literature.
 

Author(s): Floriane Gallais, Julie Denis, Olfa Koobar, Laurence Dillenseger, Dominique Astruc, Raoul Herbrecht, Ermanno Candolfi, Valérie Letscher-Bru, Marcela Sabou

Journal:

 

Primary invasive cutaneous aspergillosis is a rare fungal infection that occurs mostly in immunocompromised patients. Newborns of very low birth weight present a high risk for this type of infection due to an immaturity of the cutaneous barrier and of the immune system.

Last Updated: 31 Dec 1969

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Immune responses to invasive aspergillosis: new understanding and therapeutic opportunities.
 

Author(s): Tobias M Hohl

Journal: Curr. Opin. Infect. Dis.. 2017 Aug;30(4):364-371.

 

Invasive aspergillosis is a worldwide disease that primarily affects immune-compromised patients, agricultural workers with corneal abrasions, individuals with structural lung disease, and patients with primary immune deficiency. The critical function of the immune system is to prevent ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Impact of Pre-existing Invasive Aspergillosis on Allogeneic Stem Cell Transplantation
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis

 

Last Updated: 19 Jan 2017

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Novel Biomarkers for Invasive Aspergillosis
 

Status: Recruiting

Condition Summary: Aspergillosis Invasive

 

Last Updated: 24 Jan 2017

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Clinical Implications of Azole-Resistant Aspergillosis in Hematological Malignancy
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis

 

Last Updated: 13 Jul 2017

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