Aspergillosis

Common Name(s)

Aspergillosis

Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aspergillosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aspergillosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aspergillosis" returned 930 free, full-text research articles on human participants. First 3 results:

Fulminant Laryngeal-tracheobronchial-pulmonary Aspergillosis: A Rare and Fatal Complication in Allogeneic Hematopoietic Stem Cell Transplantation Recipients.
 

Author(s): Tao Tao, Ying-Hui Zhang, Sheng-Li Xue, De-Pei Wu, Feng Chen

Journal: Intern. Med.. 2017 ;56(3):347-351.

 

A 23-year-old man who had previously undergone allogeneic hematopoietic stem cell transplantation (allo-HSCT) for severe aplastic anemia was diagnosed with invasive laryngeal-tracheobronchial-pulmonary aspergillosis after presenting with a persistent dry cough at six months post-transplantation ...

Last Updated: 3 Feb 2017

Go To URL
A rare disease mimics postoperative bile leakage: Invasive aspergillosis.
 

Author(s): Fatih Mehmet Yazar, Aykut Urfalıoğlu, Ömer Faruk Boran, Hamide Sayar, Burhan Hakan Kanat, Arif Emre, Emrah Cengiz, Ertan Bülbüloğlu

Journal: Ulus Travma Acil Cerrahi Derg. 2016 Sep;22(5):498-501.

 

Aspergillus fungi can cause serious infections, including intra-abdominal infection, particularly in patients with compromised immune system. Described in the present report is case of 46-year-old female patient who had undergone laparoscopic cholecystectomy (LC) at another healthcare ...

Last Updated: 16 Nov 2016

Go To URL
Application of a low molecular weight antifungal protein from Penicillium chrysogenum (PAF) to treat pulmonary aspergillosis in mice.
 

Author(s): Zoltán Palicz, Tamás Gáll, Éva Leiter, Sándor Kollár, Ilona Kovács, Kornél Miszti-Blasius, István Pócsi, László Csernoch, Péter Szentesi

Journal:

 

PAF, a small antifungal protein from Penicillium chrysogenum, inhibits the growth of several pathogenic filamentous fungi, including members of the Aspergillus genus. PAF has been proven to have no toxic effects in vivo in mice by intranasal application. To test its efficacy against ...

Last Updated: 9 Nov 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aspergillosis" returned 108 free, full-text review articles on human participants. First 3 results:

[Invasive pulmonary aspergillosis in non-neutropenic patients].
 

Author(s): M I Tejeda, S Salso, J Barberán

Journal: Rev Esp Quimioter. 2016 Sep;29 Suppl 1():56-8.

 

The incidence of invasive pulmonary aspergillosis (IPA) is increasing among non-neutropenic patients in recent years. The difficulty of early diagnosis in these patients involves a delay in the onset of adequate treatment and higher mortality.

Last Updated: 9 Sep 2016

Go To URL
Factors affecting patient outcome in primary cutaneous aspergillosis.
 

Author(s): Alexander M Tatara, Antonios G Mikos, Dimitrios P Kontoyiannis

Journal: Medicine (Baltimore). 2016 Jun;95(26):e3747.

 

Primary cutaneous aspergillosis (PCA) is an uncommon infection of the skin. There is a paucity of organized literature regarding this entity in regard to patient characteristics, associated Aspergillus species, and treatment modalities on outcome (disease recurrence, disease dissemination, ...

Last Updated: 2 Jul 2016

Go To URL
Aspergillosis of the Heart and Lung and Review of Published Reports on Fungal Endocarditis.
 

Author(s): Beata Sulik-Tyszka, Piotr Kacprzyk, Krzysztof Mądry, Bogna Ziarkiewicz-Wróblewska, Wiesław Jędrzejczak, Marta Wróblewska

Journal: Mycopathologia. 2016 Aug;181(7-8):583-8.

 

Invasive aspergillosis (IA) is increasingly diagnosed in high-risk patients. The lesions are usually located in the lungs and/or sinuses, and the fungus may spread haematogenously to different organs; however, involvement of the heart during IA is very rare. We describe a unique case ...

Last Updated: 8 Jul 2016

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Impact of Pre-existing Invasive Aspergillosis on Allogeneic Stem Cell Transplantation
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis

 

Last Updated: 19 Jan 2017

Go to URL
Novel Biomarkers for Invasive Aspergillosis
 

Status: Recruiting

Condition Summary: Aspergillosis Invasive

 

Last Updated: 24 Jan 2017

Go to URL
Aspergillus-specific IgG Assays for the Diagnosis of Chronic Pulmonary Aspergillosis (CPA)-Multicenter Study
 

Status: Recruiting

Condition Summary: Chronic Pulmonary Aspergillosis

 

Last Updated: 18 Jan 2017

Go to URL