Aspergillosis

Common Name(s)

Aspergillosis

Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aspergillosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aspergillosis" returned 933 free, full-text research articles on human participants. First 3 results:

Fulminant Laryngeal-tracheobronchial-pulmonary Aspergillosis: A Rare and Fatal Complication in Allogeneic Hematopoietic Stem Cell Transplantation Recipients.
 

Author(s): Tao Tao, Ying-Hui Zhang, Sheng-Li Xue, De-Pei Wu, Feng Chen

Journal: Intern. Med.. 2017 ;56(3):347-351.

 

A 23-year-old man who had previously undergone allogeneic hematopoietic stem cell transplantation (allo-HSCT) for severe aplastic anemia was diagnosed with invasive laryngeal-tracheobronchial-pulmonary aspergillosis after presenting with a persistent dry cough at six months post-transplantation ...

Last Updated: 3 Feb 2017

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Application of a low molecular weight antifungal protein from Penicillium chrysogenum (PAF) to treat pulmonary aspergillosis in mice.
 

Author(s): Zoltán Palicz, Tamás Gáll, Éva Leiter, Sándor Kollár, Ilona Kovács, Kornél Miszti-Blasius, István Pócsi, László Csernoch, Péter Szentesi

Journal:

 

PAF, a small antifungal protein from Penicillium chrysogenum, inhibits the growth of several pathogenic filamentous fungi, including members of the Aspergillus genus. PAF has been proven to have no toxic effects in vivo in mice by intranasal application. To test its efficacy against ...

Last Updated: 9 Nov 2016

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Utility of the serum galactomannan assay for the diagnosis of invasive aspergillosis in children with acute lymphoblastic leukemia.
 

Author(s): Gulhadiye Avcu, Deniz Yilmaz Karapinar, Ayse Burcu Akinci, Zuhal Onder Sivis, Akkiz Sahin, Zumrut Sahbudak Bal, Suleyha Hilmioglu Polat, Dilek Yesim Metin, Fadil Vardar, Yesim Aydinok

Journal: Int. J. Infect. Dis.. 2017 Jan;54():8-12.

 

Invasive aspergillosis (IA) is an important cause of mortality and morbidity in children with hematological malignancies. The monitoring of serum galactomannan (GM) antigen is considered useful in the diagnosis of IA . The aim of this study was to determine the utility of serum GM ...

Last Updated: 5 Nov 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aspergillosis" returned 106 free, full-text review articles on human participants. First 3 results:

[Invasive pulmonary aspergillosis in non-neutropenic patients].
 

Author(s): M I Tejeda, S Salso, J Barberán

Journal: Rev Esp Quimioter. 2016 Sep;29 Suppl 1():56-8.

 

The incidence of invasive pulmonary aspergillosis (IPA) is increasing among non-neutropenic patients in recent years. The difficulty of early diagnosis in these patients involves a delay in the onset of adequate treatment and higher mortality.

Last Updated: 9 Sep 2016

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Factors affecting patient outcome in primary cutaneous aspergillosis.
 

Author(s): Alexander M Tatara, Antonios G Mikos, Dimitrios P Kontoyiannis

Journal: Medicine (Baltimore). 2016 Jun;95(26):e3747.

 

Primary cutaneous aspergillosis (PCA) is an uncommon infection of the skin. There is a paucity of organized literature regarding this entity in regard to patient characteristics, associated Aspergillus species, and treatment modalities on outcome (disease recurrence, disease dissemination, ...

Last Updated: 2 Jul 2016

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Allergic bronchopulmonary aspergillosis in a patient with rheumatoid arthritis under adalimumab therapy: a case report.
 

Author(s): Tatsuya Kawasaki, Mari Kamiya, Atsushi Nakagawa, Jun Takagiwa, Yutaka Kawahara, Yoshinori Nonomura

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2016 ;39(1):84-9.

 

  A 77-year-old woman with a 15-year history of rheumatoid arthritis (RA) was admitted to our hospital because of a wet cough that persisted for 1 month. The patient had been taking methotrexate (MTX) and adalimumab (ADA) for the past 3 years, and disease activity of RA was low. ...

Last Updated: 16 May 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Impact of Pre-existing Invasive Aspergillosis on Allogeneic Stem Cell Transplantation
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis

 

Last Updated: 19 Jan 2017

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Novel Biomarkers for Invasive Aspergillosis
 

Status: Recruiting

Condition Summary: Aspergillosis Invasive

 

Last Updated: 24 Jan 2017

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Exhaled Breath Analysis in the Early Detection of Aspergillosis
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis

 

Last Updated: 1 Apr 2015

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