Aspergillosis

Common Name(s)

Aspergillosis

Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aspergillosis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aspergillosis" returned 847 free, full-text research articles on human participants. First 3 results:

PTX3 deficiency and aspergillosis.
 

Author(s): Cristina Cunha, Oliver Kurzai, Agostinho Carvalho

Journal: N. Engl. J. Med.. 2014 Apr;370(17):1666-7.

 

Last Updated: 24 Apr 2014

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Invasive aspergillosis in kidney transplant recipients: a cohort study.
 

Author(s): Maria José Pérez-Sáez, Marisa Mir, Maria Milagro Montero, Marta Crespo, Núria Montero, Julià Gómez, Juan Pablo Horcajada, Julio Pascual

Journal: Exp Clin Transplant. 2014 Apr;12(2):101-5.

 

Fungal infections represent 5% of infections in renal transplant recipients. Candidiasis is the most frequent, followed by aspergillosis and cryptococcosis. Invasive aspergillosis is severe and has a poor prognosis, but recent series focused on outcomes are scarce in the literature. ...

Last Updated: 7 Apr 2014

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[Evaluation of galactomannan antigen and Aspergillus real time PCR for diagnosis of invasive aspergillosis].
 

Author(s): M Chanzá, M T Fraile, C Gimeno, M D Ocete

Journal: Rev Esp Quimioter. 2014 Mar;27(1):43-5.

 

The aim of the study was to compare the galactomannan antigen (GA) and molecular biology (PCRrt) tests with the culture in the diagnosis of invasive aspergillosis (IA).

Last Updated: 28 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aspergillosis" returned 95 free, full-text review articles on human participants. First 3 results:

Allergic aspergillosis of the respiratory tract.
 

Author(s): Ashok Shah, Chandramani Panjabi

Journal: Eur Respir Rev. 2014 Mar;23(131):8-29.

 

Last Updated: 4 Mar 2014

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[Diagnosis of invasive aspergillosis].
 

Author(s): Koichiro Yoshida

Journal: Med Mycol J. 2013 ;54(4):323-7.

 

Last Updated: 2 Dec 2013

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Last Updated: 8 Nov 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Diagnostic Accuracy of Pleural Effusion Aspergillosis Biomarker Testing
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis; Pleural Effusion; Immunosuppression

 

Last Updated: 1 Apr 2014

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Application of an Electronic Nose in the Early Detection of ASpergillosis
 

Status: Recruiting

Condition Summary: Pulmonary Invasive Aspergillosis

 

Last Updated: 14 Jul 2011

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Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis
 

Status: Recruiting

Condition Summary: Cystic Fibrosis; Allergic Bronchopulmonary Aspergillosis; A. Fumigatus

 

Last Updated: 14 Oct 2010

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