Aspergillosis

Common Name(s)

Aspergillosis

Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aspergillosis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aspergillosis" returned 878 free, full-text research articles on human participants. First 3 results:

Pleuritis clinically diagnosed as aspergillosis during the course of microscopic polyangiitis.
 

Author(s): Yasutaka Kimoto, Kensuke Oryoji, Ayumi Uchino, Shigeru Yoshizawa, Hiroaki Niiro, Hiroshi Tsukamoto, Takahiko Horiuchi

Journal: Intern. Med.. 2014 ;53(24):2821-4.

 

Pleural aspergillosis is a rare fungal infection. We herein report a case of pleuritis clinically diagnosed as aspergillosis without apparent Aspergillus lung lesions. A 75-year-old man receiving immunosuppressive therapy due to microscopic polyangiitis was admitted for treatment ...

Last Updated: 16 Dec 2014

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Pulmonary toxocariasis mimicking invasive aspergillosis in a patient with ulcerative colitis.
 

Author(s): Eun Jin Park, Joon Young Song, Min Ju Choi, Ji Ho Jeon, Jah-Yeon Choi, Tae Un Yang, Kyung Wook Hong, Ji Yun Noh, Hee Jin Cheong, Woo Joo Kim

Journal: Korean J. Parasitol.. 2014 Aug;52(4):425-8.

 

A 45-year-old-male who had underlying ulcerative colitis and presented with fever and dry cough. Initially, the patient was considered to have invasive aspergillosis due to a positive galactomannan assay. He was treated with amphotericin B followed by voriconazole. Nevertheless, the ...

Last Updated: 23 Sep 2014

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Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction.
 

Author(s): Luna Azulay-Abulafia, Maria Auxiliadora Jeunon Sousa, Andrea Pussanti, Daniel Dal'Asta Coimbra, Hernando Vega, Fred Bernardes Filho

Journal: Rev. Soc. Bras. Med. Trop.. 2014 Jul;47(4):533-6.

 

Aspergillosis is an infection caused by saprophytic fungi of the genus Aspergillus, which typically occurs in immunosuppressed individuals, but has also been reported in immunocompetent patients. The main routes of entry are the respiratory tract, skin, cornea, and ear, and the infection ...

Last Updated: 18 Sep 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aspergillosis" returned 102 free, full-text review articles on human participants. First 3 results:

Chronic pulmonary aspergillosis: an update on diagnosis and treatment.
 

Author(s): Cendrine Godet, Bruno Philippe, François Laurent, Jacques Cadranel

Journal: Respiration. 2014 ;88(2):162-74.

 

Chronic pulmonary aspergillosis (CPA) affects individuals with non-systemic or mildly systemic immunodepression or altered pulmonary integrity due to underlying disease. It has been reported with a variety of clinical and radiological patterns. The condition should be distinguished ...

Last Updated: 30 Jul 2014

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Role of inhaled amphotericin in allergic bronchopulmonary aspergillosis.
 

Author(s): I S Sehgal, R Agarwal

Journal: J Postgrad Med. ;60(1):41-5.

 

Allergic bronchopulmonary aspergillosis (ABPA) is an immunological pulmonary disorder caused by immune reactions mounted against the ubiquitous fungus Aspergillus fumigatus. The disease clinically manifests with poorly controlled asthma, hemoptysis, systemic manifestations like fever, ...

Last Updated: 14 Mar 2014

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Allergic aspergillosis of the respiratory tract.
 

Author(s): Ashok Shah, Chandramani Panjabi

Journal: Eur Respir Rev. 2014 Mar;23(131):8-29.

 

Last Updated: 4 Mar 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Diagnostic Accuracy of Pleural Effusion Aspergillosis Biomarker Testing
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis; Pleural Effusion; Immunosuppression

 

Last Updated: 1 Apr 2014

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Application of an Electronic Nose in the Early Detection of ASpergillosis
 

Status: Recruiting

Condition Summary: Pulmonary Invasive Aspergillosis

 

Last Updated: 14 Jul 2011

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Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis
 

Status: Recruiting

Condition Summary: Cystic Fibrosis; Allergic Bronchopulmonary Aspergillosis; A. Fumigatus

 

Last Updated: 14 Oct 2010

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