Aspergillosis

Common Name(s)

Aspergillosis

Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aspergillosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aspergillosis" returned 884 free, full-text research articles on human participants. First 3 results:

Tumoral presentation of invasive cerebral aspergillosis.
 

Author(s): Andreia Matas, Andreia Veiga, João Paulo Gabriel

Journal: Rev. Soc. Bras. Med. Trop.. ;48(1):115.

 

Last Updated: 11 Apr 2015

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Aspergillosis of the bone.
 

Author(s): T M Dabkana, Umaru H Pindiga, Ahmed A Mayun, Haruna A Nggada

Journal: Ann Afr Med. ;14(1):62-4.

 

Aspergillosis of the long bones has not been reported. Those of the bones of the paranasal sinuses and ear canal have been reported but rare. A young woman reported to us with history of discharging sinuses around the right knee and recent fracture of the right femur. Despite all ...

Last Updated: 8 Jan 2015

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Pleuritis clinically diagnosed as aspergillosis during the course of microscopic polyangiitis.
 

Author(s): Yasutaka Kimoto, Kensuke Oryoji, Ayumi Uchino, Shigeru Yoshizawa, Hiroaki Niiro, Hiroshi Tsukamoto, Takahiko Horiuchi

Journal: Intern. Med.. 2014 ;53(24):2821-4.

 

Pleural aspergillosis is a rare fungal infection. We herein report a case of pleuritis clinically diagnosed as aspergillosis without apparent Aspergillus lung lesions. A 75-year-old man receiving immunosuppressive therapy due to microscopic polyangiitis was admitted for treatment ...

Last Updated: 16 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aspergillosis" returned 104 free, full-text review articles on human participants. First 3 results:

Chronic pulmonary aspergillosis: an update on diagnosis and treatment.
 

Author(s): Cendrine Godet, Bruno Philippe, François Laurent, Jacques Cadranel

Journal: Respiration. 2014 ;88(2):162-74.

 

Chronic pulmonary aspergillosis (CPA) affects individuals with non-systemic or mildly systemic immunodepression or altered pulmonary integrity due to underlying disease. It has been reported with a variety of clinical and radiological patterns. The condition should be distinguished ...

Last Updated: 30 Jul 2014

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Immune correlates of protection in human invasive aspergillosis.
 

Author(s): Jose F Camargo, Shahid Husain

Journal: Clin. Infect. Dis.. 2014 Aug;59(4):569-77.

 

Protective immunity against Aspergillus depends on a highly coordinated interaction between the innate and adaptive arms of the immune system. Fungal recognition via pattern recognition receptors, such as pentraxin 3, dectin-1, and Toll-like receptors, leads to complement activation, ...

Last Updated: 28 Jul 2014

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Role of inhaled amphotericin in allergic bronchopulmonary aspergillosis.
 

Author(s): I S Sehgal, R Agarwal

Journal: J Postgrad Med. ;60(1):41-5.

 

Allergic bronchopulmonary aspergillosis (ABPA) is an immunological pulmonary disorder caused by immune reactions mounted against the ubiquitous fungus Aspergillus fumigatus. The disease clinically manifests with poorly controlled asthma, hemoptysis, systemic manifestations like fever, ...

Last Updated: 14 Mar 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Diagnostic Accuracy of Pleural Effusion Aspergillosis Biomarker Testing
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis; Pleural Effusion; Immunosuppression

 

Last Updated: 1 Apr 2014

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Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis
 

Status: Recruiting

Condition Summary: Cystic Fibrosis; Allergic Bronchopulmonary Aspergillosis; A. Fumigatus

 

Last Updated: 14 Oct 2010

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Voriconazole Versus Oral Steroids in Allergic Bronchopulmonary Aspergillosis
 

Status: Recruiting

Condition Summary: Allergic Bronchopulmonary Aspergillosis

 

Last Updated: 26 Dec 2014

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