Aspergillosis

Common Name(s)

Aspergillosis

Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aspergillosis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aspergillosis" returned 949 free, full-text research articles on human participants. First 3 results:

Is Bulpa criteria suitable for the diagnosis of probable invasive pulmonary Aspergillosis in critically ill patients with chronic obstructive pulmonary disease? A comparative study with EORTC/ MSG and ICU criteria.
 

Author(s): Linna Huang, Hangyong He, Jingjing Jin, Qingyuan Zhan

Journal:

 

Three diagnostic criteria have been proposed used for invasive pulmonary aspergillosis (IPA) diagnosis, namely EORTC/ MSG criteria, Bulpa criteria and intensive care unit (ICU) criteria. The Bulpa criteria were proposed to diagnose IPA in chronic obstructive pulmonary disease (COPD) ...

Last Updated: 15 Mar 2017

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Unexpected extrapyramidal symptoms and pulmonary aspergillosis in exertional heatstroke with fulminant liver failure: a case report.
 

Author(s): Jie Jiao, Feihu Zhou, Hongjun Kang, Chao Liu, Mengmeng Yang, Jie Hu

Journal:

 

Exertional heatstroke is a life-threatening condition with high mortality because of the rapid progress of multiple organ dysfunction syndrome even if aggressive treatments are initiated rapidly. Mild to moderate hepatic injury is common in exertional heatstroke, while fulminant liver ...

Last Updated: 10 Feb 2017

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Fulminant Laryngeal-tracheobronchial-pulmonary Aspergillosis: A Rare and Fatal Complication in Allogeneic Hematopoietic Stem Cell Transplantation Recipients.
 

Author(s): Tao Tao, Ying-Hui Zhang, Sheng-Li Xue, De-Pei Wu, Feng Chen

Journal: Intern. Med.. 2017 ;56(3):347-351.

 

A 23-year-old man who had previously undergone allogeneic hematopoietic stem cell transplantation (allo-HSCT) for severe aplastic anemia was diagnosed with invasive laryngeal-tracheobronchial-pulmonary aspergillosis after presenting with a persistent dry cough at six months post-transplantation ...

Last Updated: 3 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aspergillosis" returned 109 free, full-text review articles on human participants. First 3 results:

Complications of chronic necrotizing pulmonary aspergillosis: review of published case reports.
 

Author(s): Aleksandra Barac, Tatjana Adzic Vukicevic, Aleksandra Dudvarski Ilic, Salvatore Rubino, Vladimir Zugic, Goran Stevanovic

Journal:

 

Chronic necrotizing pulmonary aspergillosis (CNPA), a form of chronic pulmonary aspergillosis (CPA), affects immunocompetent or mildly immunocompromised persons with underlying pulmonary disease. These conditions are associated with high morbidity and mortality and often require long-term ...

Last Updated: 19 Apr 2017

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[Invasive pulmonary aspergillosis in non-neutropenic patients].
 

Author(s): M I Tejeda, S Salso, J Barberán

Journal: Rev Esp Quimioter. 2016 Sep;29 Suppl 1():56-8.

 

The incidence of invasive pulmonary aspergillosis (IPA) is increasing among non-neutropenic patients in recent years. The difficulty of early diagnosis in these patients involves a delay in the onset of adequate treatment and higher mortality.

Last Updated: 9 Sep 2016

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Factors affecting patient outcome in primary cutaneous aspergillosis.
 

Author(s): Alexander M Tatara, Antonios G Mikos, Dimitrios P Kontoyiannis

Journal: Medicine (Baltimore). 2016 Jun;95(26):e3747.

 

Primary cutaneous aspergillosis (PCA) is an uncommon infection of the skin. There is a paucity of organized literature regarding this entity in regard to patient characteristics, associated Aspergillus species, and treatment modalities on outcome (disease recurrence, disease dissemination, ...

Last Updated: 2 Jul 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Impact of Pre-existing Invasive Aspergillosis on Allogeneic Stem Cell Transplantation
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis

 

Last Updated: 19 Jan 2017

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Novel Biomarkers for Invasive Aspergillosis
 

Status: Recruiting

Condition Summary: Aspergillosis Invasive

 

Last Updated: 24 Jan 2017

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Clinical Implications of Azole-Resistant Aspergillosis in Hematological Malignancy
 

Status: Recruiting

Condition Summary: Invasive Aspergillosis

 

Last Updated: 13 Jul 2017

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