Retinal degeneration

Common Name(s)

Retinal degeneration

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Retinal degeneration" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Retinal degeneration" returned 348 free, full-text research articles on human participants. First 3 results:

Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration.
 

Author(s): Michiko Mandai, Yasuo Kurimoto, Masayo Takahashi

Journal: N. Engl. J. Med.. 2017 08;377(8):792-793.

 

Last Updated: 23 Aug 2017

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Activated Retinal Pigment Epithelium, an Optical Coherence Tomography Biomarker for Progression in Age-Related Macular Degeneration.
 

Author(s): Christine A Curcio, Emma C Zanzottera, Thomas Ach, Chandrakumar Balaratnasingam, K Bailey Freund

Journal: Invest. Ophthalmol. Vis. Sci.. 2017 May;58(6):BIO211-BIO226.

 

To summarize and contextualize recent histology and clinical imaging publications on retinal pigment epithelium (RPE) fate in advanced age-related macular degeneration (AMD); to support RPE activation and migration as important precursors to atrophy, manifest as intraretinal hyperreflective ...

Last Updated: 8 Aug 2017

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Segmented inner plexiform layer thickness as a potential biomarker to evaluate open-angle glaucoma: Dendritic degeneration of retinal ganglion cell.
 

Author(s): Eun Kyoung Kim, Hae-Young Lopilly Park, Chan Kee Park

Journal:

 

To evaluate the changes of retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), and ganglion cell-inner plexiform layer (GCIPL) thicknesses and compare structure-function relationships of 4 retinal layers using spectral-domain optical coherence ...

Last Updated: 3 Aug 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Retinal degeneration" returned 48 free, full-text review articles on human participants. First 3 results:

Biochemical Measurements of Free Opsin in Macular Degeneration Eyes: Examining the 11-CIS Retinal Deficiency Hypothesis of Delayed Dark Adaptation (An American Ophthalmological Society Thesis).
 

Author(s): Anne Hanneken, Thomas Neikirk, Jennifer Johnson, Masahiro Kono

Journal:

 

To test the hypothesis that delayed dark adaptation in patients with macular degeneration is due to an excess of free unliganded opsin (apo-opsin) and a deficiency of the visual chromophore, 11-cis retinal, in rod outer segments.

Last Updated: 13 Sep 2017

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Neuroprotective Strategy in Retinal Degeneration: Suppressing ER Stress-Induced Cell Death via Inhibition of the mTOR Signal.
 

Author(s): Bin Fan, Ying-Jian Sun, Shu-Yan Liu, Lin Che, Guang-Yu Li

Journal:

 

The retina is a specialized sensory organ, which is essential for light detection and visual formation in the human eye. Inherited retinal degenerations are a heterogeneous group of eye diseases that can eventually cause permanent vision loss. UPR (unfolded protein response) and ER ...

Last Updated: 20 Jan 2017

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Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration.
 

Author(s): Kai Kaarniranta, Paulina Tokarz, Ali Koskela, Jussi Paterno, Janusz Blasiak

Journal: Cell Biol. Toxicol.. 2017 Apr;33(2):113-128.

 

Age-related macular degeneration (AMD) is an eye disease underlined by the degradation of retinal pigment epithelium (RPE) cells, photoreceptors, and choriocapillares, but the exact mechanism of cell death in AMD is not completely clear. This mechanism is important for prevention ...

Last Updated: 30 Nov 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Quality of Life Measures in Patients With Retinal Degeneration
 

Status: Recruiting

Condition Summary: Retinal Degeneration

 

Last Updated: 12 Jul 2016

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Natural History of Eye Diseases Related to ABCA4 Mutations
 

Status: Recruiting

Condition Summary: Retinal Degeneration; ABCA4-Related Retinopathies

 

Last Updated: 18 Oct 2017

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Stem Cell Therapy for Outer Retinal Degenerations
 

Status: Recruiting

Condition Summary: Age Related Macular Degeneration; Stargardt's Disease; Exudative Age-related Macular Degeneration

 

Last Updated: 8 Aug 2017

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