Retinal degeneration

Common Name(s)

Retinal degeneration

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Retinal degeneration" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Retinal degeneration" returned 318 free, full-text research articles on human participants. First 3 results:

Fully Automated Robust System to Detect Retinal Edema, Central Serous Chorioretinopathy, and Age Related Macular Degeneration from Optical Coherence Tomography Images.
 

Author(s): Samina Khalid, M Usman Akram, Taimur Hassan, Ammara Nasim, Amina Jameel

Journal: Biomed Res Int. 2017 ;2017():7148245.

 

Maculopathy is the excessive damage to macula that leads to blindness. It mostly occurs due to retinal edema (RE), central serous chorioretinopathy (CSCR), or age related macular degeneration (ARMD). Optical coherence tomography (OCT) imaging is the latest eye testing technique that ...

Last Updated: 20 Apr 2017

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Spermidine Oxidation-Mediated Degeneration of Retinal Pigment Epithelium in Rats.
 

Author(s): Koji Ohashi, Masaaki Kageyama, Katsuhiko Shinomiya, Yukie Fujita-Koyama, Shin-Ichiro Hirai, Osamu Katsuta, Masatsugu Nakamura

Journal: Oxid Med Cell Longev. 2017 ;2017():4128061.

 

Retinal pigment epithelium (RPE) degeneration is a crucial event in dry age-related macular degeneration and gyrate atrophy. The polyamine spermidine has been shown to induce RPE cell death in vitro. The present study aimed to establish a novel in vivo model of spermidine-induced ...

Last Updated: 3 Apr 2017

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Gene expression changes in the retina following subretinal injection of human neural progenitor cells into a rodent model for retinal degeneration.
 

Author(s): Melissa K Jones, Bin Lu, Mehrnoosh Saghizadeh, Shaomei Wang

Journal:

 

Retinal degenerative diseases (RDDs) affect millions of people and are the leading cause of vision loss. Although treatment options for RDDs are limited, stem and progenitor cell-based therapies have great potential to halt or slow the progression of vision loss. Our previous studies ...

Last Updated: 24 May 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Retinal degeneration" returned 45 free, full-text review articles on human participants. First 3 results:

Neuroprotective Strategy in Retinal Degeneration: Suppressing ER Stress-Induced Cell Death via Inhibition of the mTOR Signal.
 

Author(s): Bin Fan, Ying-Jian Sun, Shu-Yan Liu, Lin Che, Guang-Yu Li

Journal:

 

The retina is a specialized sensory organ, which is essential for light detection and visual formation in the human eye. Inherited retinal degenerations are a heterogeneous group of eye diseases that can eventually cause permanent vision loss. UPR (unfolded protein response) and ER ...

Last Updated: 20 Jan 2017

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Retinal degeneration following lead exposure - functional aspects.
 

Author(s): Andrzej Sobieniecki, Izabela Gutowska, Anna MachaliƄska, Dariusz Chlubek, Irena Baranowska-Bosiacka

Journal:

 

Due to the prevalence of lead (Pb) in the environment, the neurotoxic effects on the human body have become an important clinical problem. Despite that Pb concentration in the environment decreased after banning its use in petrol, it is still a significant issue which can affect child ...

Last Updated: 16 Dec 2015

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Therapeutic Approaches to Histone Reprogramming in Retinal Degeneration.
 

Author(s): Andre K Berner, Mark E Kleinman

Journal: Adv. Exp. Med. Biol.. 2016 ;854():39-44.

 

Recent data have revealed epigenetic derangements and subsequent chromatin remodeling as a potent biologic switch for chronic inflammation and cell survival which are important therapeutic targets in the pathogenesis of several retinal degenerations. Histone deacetylases (HDACs) are ...

Last Updated: 2 Oct 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Quality of Life Measures in Patients With Retinal Degeneration
 

Status: Recruiting

Condition Summary: Retinal Degeneration

 

Last Updated: 12 Jul 2016

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Natural History of Eye Diseases Related to ABCA4 Mutations
 

Status: Recruiting

Condition Summary: Retinal Degeneration; ABCA4-Related Retinopathies

 

Last Updated: 21 Apr 2017

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Stem Cell Therapy for Outer Retinal Degenerations
 

Status: Recruiting

Condition Summary: Age Related Macular Degeneration; Stargardt's Disease; Exudative Age-related Macular Degeneration

 

Last Updated: 13 Feb 2017

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