Retinal degeneration

Common Name(s)

Retinal degeneration

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Retinal degeneration" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Retinal degeneration" returned 333 free, full-text research articles on human participants. First 3 results:

Gene expression changes in the retina following subretinal injection of human neural progenitor cells into a rodent model for retinal degeneration.
 

Author(s): Melissa K Jones, Bin Lu, Mehrnoosh Saghizadeh, Shaomei Wang

Journal:

 

Retinal degenerative diseases (RDDs) affect millions of people and are the leading cause of vision loss. Although treatment options for RDDs are limited, stem and progenitor cell-based therapies have great potential to halt or slow the progression of vision loss. Our previous studies ...

Last Updated: 24 May 2016

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The role of sub-retinal fluid in determining treatment outcomes in patients with neovascular age-related macular degeneration--a phase IV randomised clinical trial with ranibizumab: the FLUID study.
 

Author(s): Jennifer J Arnold, Caroline M Markey, Nicol P Kurstjens, Robyn H Guymer

Journal:

 

With increasing experience using anti-VEGF therapy for the treatment of neovascular age-related macular degeneration (nAMD), ophthalmologists have shifted away from a "one size fits all" to an "individualised" approach based on disease activity with the aim of achieving a fluid-free ...

Last Updated: 24 Mar 2016

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Involvement of Endoplasmic Reticulum Stress in TULP1 Induced Retinal Degeneration.
 

Author(s): Glenn P Lobo, Adrian Au, Philip D Kiser, Stephanie A Hagstrom

Journal:

 

Inherited retinal disorders (IRDs) result in severe visual impairments in children and adults. A challenge in the field of retinal degenerations is identifying mechanisms of photoreceptor cell death related to specific genetic mutations. Mutations in the gene TULP1 have been associated ...

Last Updated: 18 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Retinal degeneration" returned 42 free, full-text review articles on human participants. First 3 results:

Retinal degeneration following lead exposure - functional aspects.
 

Author(s): Andrzej Sobieniecki, Izabela Gutowska, Anna MachaliƄska, Dariusz Chlubek, Irena Baranowska-Bosiacka

Journal:

 

Due to the prevalence of lead (Pb) in the environment, the neurotoxic effects on the human body have become an important clinical problem. Despite that Pb concentration in the environment decreased after banning its use in petrol, it is still a significant issue which can affect child ...

Last Updated: 16 Dec 2015

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Therapeutic Approaches to Histone Reprogramming in Retinal Degeneration.
 

Author(s): Andre K Berner, Mark E Kleinman

Journal: Adv. Exp. Med. Biol.. 2016 ;854():39-44.

 

Recent data have revealed epigenetic derangements and subsequent chromatin remodeling as a potent biologic switch for chronic inflammation and cell survival which are important therapeutic targets in the pathogenesis of several retinal degenerations. Histone deacetylases (HDACs) are ...

Last Updated: 2 Oct 2015

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Dementia of the eye: the role of amyloid beta in retinal degeneration.
 

Author(s): J A Ratnayaka, L C Serpell, A J Lotery

Journal: Eye (Lond). 2015 Aug;29(8):1013-26.

 

Age-related macular degeneration (AMD) is one of the most common causes of irreversible blindness affecting nearly 50 million individuals globally. The disease is characterised by progressive loss of central vision, which has significant implications for quality of life concerns in ...

Last Updated: 13 Aug 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Quality of Life Measures in Patients With Retinal Degeneration
 

Status: Recruiting

Condition Summary: Retinal Degeneration

 

Last Updated: 12 Jul 2016

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Color Vision as a Measure for Inherited Retinal Diseases
 

Status: Recruiting

Condition Summary: Healthy Volunteer; Retinal Disease; Inherited Retinal Degeneration

 

Last Updated: 31 Aug 2016

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Natural History of Eye Diseases Related to ABCA4 Mutations
 

Status: Recruiting

Condition Summary: Retinal Degeneration; ABCA4-Related Retinopathies

 

Last Updated: 31 Aug 2016

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