Retinal degeneration

Common Name(s)

Retinal degeneration

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Retinal degeneration" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Retinal degeneration" returned 305 free, full-text research articles on human participants. First 3 results:

Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin.
 

Author(s): Wei-Chieh Chiang, Victory Joseph, Douglas Yasumura, Michael T Matthes, Alfred S Lewin, Marina S Gorbatyuk, Kelly Ahern, Matthew M LaVail, Jonathan H Lin

Journal: Adv. Exp. Med. Biol.. 2016 ;854():185-91.

 

RHO (Rod opsin) encodes a G-protein coupled receptor that is expressed exclusively by rod photoreceptors of the retina and forms the essential photopigment, rhodopsin, when coupled with 11-cis-retinal. Many rod opsin disease -mutations cause rod opsin protein misfolding and trigger ...

Last Updated: 2 Oct 2015

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Molecular Heterogeneity Within the Clinical Diagnosis of Pericentral Retinal Degeneration.
 

Author(s): Rodrigo Matsui, Artur V Cideciyan, Sharon B Schwartz, Alexander Sumaroka, Alejandro J Roman, Malgorzata Swider, Wei Chieh Huang, Rebecca Sheplock, Samuel G Jacobson

Journal: Invest. Ophthalmol. Vis. Sci.. 2015 Sep;56(10):6007-18.

 

To characterize in detail the phenotype and genotype of patients with pericentral retinal degeneration (PRD).

Last Updated: 23 Sep 2015

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Safety and Efficacy of Human Wharton's Jelly-Derived Mesenchymal Stem Cells Therapy for Retinal Degeneration.
 

Author(s): S N Leow, Chi D Luu, M H Hairul Nizam, P L Mok, R Ruhaslizan, H S Wong, Wan Haslina Wan Abdul Halim, M H Ng, B H I Ruszymah, S R Chowdhury, M L C Bastion, K Y Then

Journal:

 

To investigate the safety and efficacy of subretinal injection of human Wharton's Jelly-derived mesenchymal stem cells (hWJ-MSCs) on retinal structure and function in Royal College of Surgeons (RCS) rats.

Last Updated: 25 Jun 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Retinal degeneration" returned 39 free, full-text review articles on human participants. First 3 results:

Dementia of the eye: the role of amyloid beta in retinal degeneration.
 

Author(s): J A Ratnayaka, L C Serpell, A J Lotery

Journal: Eye (Lond). 2015 Aug;29(8):1013-26.

 

Age-related macular degeneration (AMD) is one of the most common causes of irreversible blindness affecting nearly 50 million individuals globally. The disease is characterised by progressive loss of central vision, which has significant implications for quality of life concerns in ...

Last Updated: 13 Aug 2015

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Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium.
 

Author(s): Debra A Thompson, Robin R Ali, Eyal Banin, Kari E Branham, John G Flannery, David M Gamm, William W Hauswirth, John R Heckenlively, Alessandro Iannaccone, K Thiran Jayasundera, Naheed W Khan, Robert S Molday, Mark E Pennesi, Thomas A Reh, Richard G Weleber, David N Zacks,

Journal:

 

Although rare in the general population, retinal dystrophies occupy a central position in current efforts to develop innovative therapies for blinding diseases. This status derives, in part, from the unique biology, accessibility, and function of the retina, as well as from the synergy ...

Last Updated: 10 Feb 2015

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Usher syndrome: Hearing loss, retinal degeneration and associated abnormalities.
 

Author(s): Pranav Mathur, Jun Yang

Journal: Biochim. Biophys. Acta. 2015 Mar;1852(3):406-20.

 

Usher syndrome (USH), clinically and genetically heterogeneous, is the leading genetic cause of combined hearing and vision loss. USH is classified into three types, based on the hearing and vestibular symptoms observed in patients. Sixteen loci have been reported to be involved in ...

Last Updated: 31 Jan 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Molecular Genetics of Retinal Degenerations
 

Status: Recruiting

Condition Summary: Retinal Degeneration; Retinitis Pigmentosa

 

Last Updated: 2 Dec 2015

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Treatment of Cystoid Macular Edema in Patients With Retinal Degeneration
 

Status: Recruiting

Condition Summary: Retinal Degenerations

 

Last Updated: 12 Dec 2014

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Color Vision as a Measure for Inherited Retinal Diseases
 

Status: Recruiting

Condition Summary: Healthy Volunteer; Retinal Disease; Inherited Retinal Degeneration

 

Last Updated: 6 Apr 2016

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