Retinal degeneration

Common Name(s)

Retinal degeneration

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Retinal degeneration" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Retinal degeneration" returned 368 free, full-text research articles on human participants. First 3 results:

Advanced quantitative analysis of the sub-retinal pigment epithelial space in recurrent neovascular age-related macular degeneration.
 

Author(s): Mariko Sasaki, Yu Kato, Kaoru Fujinami, Toshiaki Hirakata, Kazushige Tsunoda, Ken Watanabe, Kunihiko Akiyama, Toru Noda

Journal:

 

To quantitatively evaluate changes in the sub-retinal pigment epithelial (RPE) space and determine the association with recurrent neovascular age-related macular degeneration (AMD). Twenty-two eyes treated with intravitreal aflibercept for treatment-naïve neovascular AMD were studied ...

Last Updated: 31 Dec 1969

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Enhanced Detection of Sub-Retinal Pigment Epithelial Cell Layer Deposits in Human and Murine Tissue: Imaging Zinc as a Biomarker for Age-Related Macular Degeneration (An American Ophthalmological Society Thesis).
 

Author(s): Frederik J G M van Kuijk, Scott W McPherson, Heidi Roehrich

Journal:

 

Understanding the apparent paradoxical role of zinc in the pathogenesis and prevention of age-related macular degeneration (AMD) has been limited by the lack of animal models for its detection in sub-retinal epithelial deposits (drusen), a definitive early hallmark of AMD. In-vitro ...

Last Updated: 31 Dec 1969

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Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration.
 

Author(s): Michiko Mandai, Yasuo Kurimoto, Masayo Takahashi

Journal: N. Engl. J. Med.. 2017 08;377(8):792-793.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Retinal degeneration" returned 49 free, full-text review articles on human participants. First 3 results:

Biochemical Measurements of Free Opsin in Macular Degeneration Eyes: Examining the 11- Retinal Deficiency Hypothesis of Delayed Dark Adaptation (An American Ophthalmological Society Thesis).
 

Author(s): Anne Hanneken, Thomas Neikirk, Jennifer Johnson, Masahiro Kono

Journal:

 

To test the hypothesis that delayed dark adaptation in patients with macular degeneration is due to an excess of free unliganded opsin (apo-opsin) and a deficiency of the visual chromophore, 11 retinal, in rod outer segments.

Last Updated: 31 Dec 1969

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Progress of stem/progenitor cell-based therapy for retinal degeneration.
 

Author(s): Zhimin Tang, Yi Zhang, Yuyao Wang, Dandan Zhang, Bingqiao Shen, Min Luo, Ping Gu

Journal:

 

Retinal degeneration (RD), such as age-related macular degeneration (AMD) and retinitis pigmentosa, is one of the leading causes of blindness. Presently, no satisfactory therapeutic options are available for these diseases principally because the retina and retinal pigmented epithelium ...

Last Updated: 31 Dec 1969

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Neuroprotective Strategy in Retinal Degeneration: Suppressing ER Stress-Induced Cell Death via Inhibition of the mTOR Signal.
 

Author(s): Bin Fan, Ying-Jian Sun, Shu-Yan Liu, Lin Che, Guang-Yu Li

Journal:

 

The retina is a specialized sensory organ, which is essential for light detection and visual formation in the human eye. Inherited retinal degenerations are a heterogeneous group of eye diseases that can eventually cause permanent vision loss. UPR (unfolded protein response) and ER ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Natural History Study of CEP290-Related Retinal Degeneration
 

Status: Recruiting

Condition Summary: Retinal Degeneration

 

Last Updated: 18 May 2018

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Natural History of Eye Diseases Related to ABCA4 Mutations
 

Status: Recruiting

Condition Summary: Retinal Degeneration; ABCA4-Related Retinopathies

 

Last Updated: 24 Apr 2018

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Stem Cell Therapy for Outer Retinal Degenerations
 

Status: Recruiting

Condition Summary: Age Related Macular Degeneration; Stargardt's Disease; Exudative Age-related Macular Degeneration

 

Last Updated: 8 Aug 2017

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