Retinal degeneration

Common Name(s)

Retinal degeneration

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Retinal degeneration" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Retinal degeneration" returned 314 free, full-text research articles on human participants. First 3 results:

Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration.
 

Author(s): Hiroshi Shirai, Michiko Mandai, Keizo Matsushita, Atsushi Kuwahara, Shigenobu Yonemura, Tokushige Nakano, Juthaporn Assawachananont, Toru Kimura, Koichi Saito, Hiroko Terasaki, Mototsugu Eiraku, Yoshiki Sasai, Masayo Takahashi

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2016 Jan;113(1):E81-90.

 

Retinal transplantation therapy for retinitis pigmentosa is increasingly of interest due to accumulating evidence of transplantation efficacy from animal studies and development of techniques for the differentiation of human embryonic stem cells (hESCs) and induced pluripotent stem ...

Last Updated: 6 Jan 2016

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Tyro3 Modulates Mertk-Associated Retinal Degeneration.
 

Author(s): Douglas Vollrath, Douglas Yasumura, Gillie Benchorin, Michael T Matthes, Wei Feng, Natalie M Nguyen, Cecilia D Sedano, Melissa A Calton, Matthew M LaVail

Journal:

 

Inherited photoreceptor degenerations (IPDs) are the most genetically heterogeneous of Mendelian diseases. Many IPDs exhibit substantial phenotypic variability, but the basis is usually unknown. Mutations in MERTK cause recessive IPD phenotypes associated with the RP38 locus. We have ...

Last Updated: 15 Dec 2015

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Comparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration.
 

Author(s): Anna Bennis, Theo G M F Gorgels, Jacoline B Ten Brink, Peter J van der Spek, Koen Bossers, Vivi M Heine, Arthur A Bergen

Journal:

 

The human retinal pigment epithelium (RPE) plays an important role in the pathogenesis of age related macular degeneration (AMD). AMD is the leading cause of blindness worldwide. There is currently no effective treatment available. Preclinical studies in AMD mouse models are essential ...

Last Updated: 31 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Retinal degeneration" returned 40 free, full-text review articles on human participants. First 3 results:

Retinal degeneration following lead exposure - functional aspects.
 

Author(s): Andrzej Sobieniecki, Izabela Gutowska, Anna MachaliƄska, Dariusz Chlubek, Irena Baranowska-Bosiacka

Journal:

 

Due to the prevalence of lead (Pb) in the environment, the neurotoxic effects on the human body have become an important clinical problem. Despite that Pb concentration in the environment decreased after banning its use in petrol, it is still a significant issue which can affect child ...

Last Updated: 16 Dec 2015

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Dementia of the eye: the role of amyloid beta in retinal degeneration.
 

Author(s): J A Ratnayaka, L C Serpell, A J Lotery

Journal: Eye (Lond). 2015 Aug;29(8):1013-26.

 

Age-related macular degeneration (AMD) is one of the most common causes of irreversible blindness affecting nearly 50 million individuals globally. The disease is characterised by progressive loss of central vision, which has significant implications for quality of life concerns in ...

Last Updated: 13 Aug 2015

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Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium.
 

Author(s): Debra A Thompson, Robin R Ali, Eyal Banin, Kari E Branham, John G Flannery, David M Gamm, William W Hauswirth, John R Heckenlively, Alessandro Iannaccone, K Thiran Jayasundera, Naheed W Khan, Robert S Molday, Mark E Pennesi, Thomas A Reh, Richard G Weleber, David N Zacks,

Journal:

 

Although rare in the general population, retinal dystrophies occupy a central position in current efforts to develop innovative therapies for blinding diseases. This status derives, in part, from the unique biology, accessibility, and function of the retina, as well as from the synergy ...

Last Updated: 10 Feb 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Quality of Life Measures in Patients With Retinal Degeneration
 

Status: Recruiting

Condition Summary: Retinal Degeneration

 

Last Updated: 12 Jul 2016

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Treatment of Cystoid Macular Edema in Patients With Retinal Degeneration
 

Status: Recruiting

Condition Summary: Retinal Degenerations

 

Last Updated: 12 Dec 2014

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Color Vision as a Measure for Inherited Retinal Diseases
 

Status: Recruiting

Condition Summary: Healthy Volunteer; Retinal Disease; Inherited Retinal Degeneration

 

Last Updated: 6 Apr 2016

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