Relapsing polychondritis

Common Name(s)

Relapsing polychondritis

Relapsing polychondritis is a condition that affects connective tissue, particularly cartilage. Cartilage is a tough but flexible tissue that covers the ends of your bones at a joint, and gives shape and support to other parts of your body. Early symptoms of relapsing polychondritis may include irritation, redness, and swelling (inflammation) of the ears, nose, and/or eye. A person may experience arthritis involving multiple joints as well.  Relapsing polychondritis may affect the inner ear, heart, and skin and can cause sensorineural deafness, vertigo, aortic valve regurgitation, mitral valve regurgitation, and aneurysms.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Relapsing polychondritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Relapsing polychondritis" returned 111 free, full-text research articles on human participants. First 3 results:

Relapsing polychondritis diagnosed by transbronchial needle aspiration and (18)F-fluorodeoxyglucose positron emission tomography/computed tomography.
 

Author(s): Tao Chen, Jun-Hong Jiang, Chun-Hua Ling, Cheng Ji, Bin Zhang, Jian-An Huang

Journal: Chin. Med. J.. 2013 Oct;126(20):3930.

 

Last Updated: 25 Oct 2013

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Relapsing polychondritis complicated by giant cell myocarditis and myositis.
 

Author(s): Mari Watanabe, Hiroki Suzuki, Tomoka Ara, Midori Nishizuka, Mami Morita, Chisa Sato, Fumihiro Tsuchida, Hiroaki Takeda, Tomoya Kato

Journal: Intern. Med.. 2013 ;52(12):1397-402.

 

An 83-year-old man presented with a three-week history of dyspnea. The clinical features suggested a diagnosis of relapsing polychondritis (RP); however, the patient died of heart failure. An autopsy revealed active chondritis of the tracheal and bronchial cartilage. Furthermore, ...

Last Updated: 18 Jun 2013

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Successful treatment with noninvasive positive-pressure ventilation based on the prediction of disease onset using CT and respiratory function tests in an elderly patient with relapsing polychondritis.
 

Author(s): Hiromichi Yamaguchi, Yuko Komase, Ayami Ono, Akane Morita, Akira Ishida

Journal: Intern. Med.. 2013 ;52(10):1085-9.

 

An 83-year-old man who had been receiving treatment for bronchial asthma since 62 years of age experienced difficulty breathing on exertion and was admitted to the hospital. On admission, computed tomography revealed tracheal wall thickening, while test results for antinuclear antibodies ...

Last Updated: 16 May 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Relapsing polychondritis" returned 4 free, full-text review articles on human participants. First 3 results:

[Airway involvement in relapsing polychondritis].
 

Author(s): Naoto Azuma

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2012 ;35(3):157-67.

 

Relapsing Polychondritis (RP) is an uncommon, chronic, and potentially life-threatening multisystem disorder characterized by recurrent inflammatory episodes affecting the cartilaginous tissues of the external ears, nose, peripheral joints, larynx and tracheobronchial tree, sometimes ...

Last Updated: 13 Jul 2012

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[Manifestations mimicking relapsing polychondritis in a patient with microscopic polyangiitis].
 

Author(s): Hiroe Ogawa, Eiko Nishi, Hideto Kameda, Koichi Amano, Tsutomu Takeuchi

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2005 Apr;28(2):104-8.

 

Microscopic polyangiitis (MPA) is a systemic disorder characterized by inflammation of small vessels mainly affecting the kidneys and lungs. We describe a 72-year-old woman who developed multiple cartilage involvements as well as major manifestations of MPA. The left ear biopsy demonstrated ...

Last Updated: 2 May 2005

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Cartilage-specific autoimmunity in animal models and clinical aspects in patients - focus on relapsing polychondritis.
 

Author(s): Ann-Sofie Hansson, Rikard Holmdahl

Journal: Arthritis Res.. 2002 ;4(5):296-301.

 

Relapsing polychondritis is an autoimmune disease in which an inappropriate immune response destroys cartilage. Cartilage of the ears, larynx and nose rather than spine and joint cartilage is affected by a chronic relapsing and erosive inflammation. Several animal models for relapsing ...

Last Updated: 11 Sep 2002

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.