Relapsing polychondritis

Common Name(s)

Relapsing polychondritis

Relapsing polychondritis is a condition that affects connective tissue, particularly cartilage. Cartilage is a tough but flexible tissue that covers the ends of your bones at a joint, and gives shape and support to other parts of your body. Early symptoms of relapsing polychondritis may include irritation, redness, and swelling (inflammation) of the ears, nose, and/or eye. A person may experience arthritis involving multiple joints as well.  Relapsing polychondritis may affect the inner ear, heart, and skin and can cause sensorineural deafness, vertigo, aortic valve regurgitation, mitral valve regurgitation, and aneurysms.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Relapsing polychondritis" for support, advocacy or research.

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Relapsing Polychondritis Awareness and Support Foundation

Advocating increased Awareness and Support for persons affected by Relapsing Polychondritis. The Relapsing Polychondritis Awareness and Support Foundation, Inc. is a non-profit organization dedicated to supporting and advocating research, providing patient and family assistance and educating the general public and medical communities an increased awareness and support of Relapsing Polychondritis.

Last Updated: 19 May 2015

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Relapsing polychondritis" for support, advocacy or research.

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Relapsing Polychondritis Awareness and Support Foundation

Advocating increased Awareness and Support for persons affected by Relapsing Polychondritis. The Relapsing Polychondritis Awareness and Support Foundation, Inc. is a non-profit organization dedicated to supporting and advocating research, providing patient and family assistance and educating the general public and medical communities an increased awareness and support of Relapsing Polychondritis.

http://www.polychondritis.org

Last Updated: 19 May 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Relapsing polychondritis" returned 137 free, full-text research articles on human participants. First 3 results:

Relapsing Polychondritis Presenting with Meningoencephalitis and Dementia: Correlation with Neuroimaging and Clinical Features.
 

Author(s): Yung-Pin Hwang, Richard Kuo, Tien-Ling Chen, Pei-Hao Chen, Shih-Jung Cheng

Journal: Acta Neurol Taiwan. 2015 Mar;24(1):30-3.

 

Relapsing polychondritis (RP) is a rare systemic autoimmune disease affecting cartilaginous and non-cartilaginous structures. Neurological involvement is rarer but results in profound disability. Early identification and treatment of underlying RP may promote neurological recovery.

Last Updated: 16 Jul 2015

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Chronological assessment of airway lesions in relapsing polychondritis by positron emission tomography.
 

Author(s): Satoshi Ikeda, Machiko Arita, Satoshi Ikeo, Akihiro Nishiyama, Akihiro Ito, Kenjiro Furuta, Machiko Hotta, Tadashi Ishida

Journal: Intern. Med.. 2015 ;54(9):1099-102.

 

A 40-year old woman presented with pyrexia, productive cough, and bilateral precordial pain. Positron emission tomography (PET)-computed tomography (CT) showed high, diffuse F-18 deoxyglucose accumulation in the tracheal, peribronchial, and bilateral costal cartilage. We diagnosed ...

Last Updated: 7 May 2015

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Relapsing polychondritis with initial presentations of recurrent negative-pressure pulmonary edema and acute respiratory failure.
 

Author(s): Meng-Fang Wu, Yi-Shan Li, Chen-Yiu Hung, Wei-Chieh Chao, Zhey-Ying Fu, Kuo-Chin Kao, Chung-Chi Huang, Ying-Huang Tsai, Meng-Jer Hsieh

Journal: Respir Care. 2015 May;60(5):e101-4.

 

Relapsing polychondritis is a rare autoimmune disease causing inflammation in cartilaginous structures and other tissues throughout the body. Negative-pressure pulmonary edema (NPPE) due to laryngeal swelling from relapsing polychondritis is rare and has not been reported. Here, we ...

Last Updated: 6 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Relapsing polychondritis" returned 8 free, full-text review articles on human participants. First 3 results:

Relapsing polychondritis with encephalitis: a case report and literature review.
 

Author(s): Mizuho Nara, Atsushi Komatsuda, Masaru Togashi, Hideki Wakui

Journal: Intern. Med.. 2015 ;54(2):231-4.

 

We herein report the case of a 39-year-old man who developed bilateral auricular chondritis, conjunctivitis, and central neurological symptoms. He was diagnosed with encephalitis associated with relapsing polychondritis (RP) based on the findings of an ear cartilage biopsy, cerebrospinal ...

Last Updated: 6 Mar 2015

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[Airway involvement in relapsing polychondritis].
 

Author(s): Naoto Azuma

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2012 ;35(3):157-67.

 

Relapsing Polychondritis (RP) is an uncommon, chronic, and potentially life-threatening multisystem disorder characterized by recurrent inflammatory episodes affecting the cartilaginous tissues of the external ears, nose, peripheral joints, larynx and tracheobronchial tree, sometimes ...

Last Updated: 13 Jul 2012

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Cholestasis as the initial presentation of relapsing polychondritis.
 

Author(s): Maria da Graça Ferronato, Leonardo Jönck Staub, Renata Cristina Teixeira Pinto Viana, Lígia da Rosa, Maria Beatriz Cacese Shiozawa, Janaína L Narciso-Schiavon, Esther Buzaglo Dantas-Correa, Leonardo de Lucca Schiavon

Journal: Ann Hepatol. ;10(4):565-7.

 

Relapsing polychondritis is an immune-mediated disease associated with inflammation in cartilaginous structures and other tissues throughout the body, particularly the ears, nose, eyes, joints, and respiratory tract. Although association with other conditions is seen in about one-third ...

Last Updated: 13 Sep 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.