Relapsing polychondritis

Common Name(s)

Relapsing polychondritis

Relapsing polychondritis is a condition that affects connective tissue, particularly cartilage. Cartilage is a tough but flexible tissue that covers the ends of your bones at a joint, and gives shape and support to other parts of your body. Early symptoms of relapsing polychondritis may include irritation, redness, and swelling (inflammation) of the ears, nose, and/or eye. A person may experience arthritis involving multiple joints as well.  Relapsing polychondritis may affect the inner ear, heart, and skin and can cause sensorineural deafness, vertigo, aortic valve regurgitation, mitral valve regurgitation, and aneurysms.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Relapsing polychondritis" for support, advocacy or research.

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Relapsing Polychondritis Awareness and Support Foundation

Advocating increased Awareness and Support for persons affected by Relapsing Polychondritis. The Relapsing Polychondritis Awareness and Support Foundation, Inc. is a non-profit organization dedicated to supporting and advocating research, providing patient and family assistance and educating the general public and medical communities an increased awareness and support of Relapsing Polychondritis.

Last Updated: 19 May 2015

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Relapsing polychondritis" for support, advocacy or research.

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Relapsing Polychondritis Awareness and Support Foundation

Advocating increased Awareness and Support for persons affected by Relapsing Polychondritis. The Relapsing Polychondritis Awareness and Support Foundation, Inc. is a non-profit organization dedicated to supporting and advocating research, providing patient and family assistance and educating the general public and medical communities an increased awareness and support of Relapsing Polychondritis.

http://www.polychondritis.org

Last Updated: 19 May 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Relapsing polychondritis" returned 126 free, full-text research articles on human participants. First 3 results:

Relapsing Polychondritis with Central Nervous System Involvement: Experience of Three Different Cases in a Single Center.
 

Author(s): Chan Hong Jeon

Journal: J. Korean Med. Sci.. 2016 Nov;31(11):1846-1850.

 

Relapsing polychondritis (RP) is an autoimmune disorder characterized by inflammation in cartilaginous structures including the ears, noses, peripheral joints, and tracheobronchial tree. It rarely involves the central nervous system (CNS) but diagnosis of CNS complication of RP is ...

Last Updated: 6 Oct 2016

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18F-FDG PET/CT imaging of relapsing polychondritis: A case report.
 

Author(s): Huijun Zhou, Minggang Su, Lin Li

Journal: Medicine (Baltimore). 2016 Aug;95(33):e4496.

 

Relapsing polychondritis (RP) is an uncommon autoimmune inflammatory disease that may affect cartilage throughout the body.

Last Updated: 19 Aug 2016

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Corticosteroid Therapy for a Patient with Relapsing Polychondritis Complicated by IgG4-Related Disease.
 

Author(s): Mari Yamasue, Shin-Ichi Nureki, Hiroyuki Matsumoto, Takamasa Kan, Takehiro Hashimoto, Ryoichi Ushijima, Yuko Usagawa, Jun-Ichi Kadota

Journal: Tohoku J. Exp. Med.. 2016 ;239(3):223-30.

 

Relapsing polychondritis (RP) is a rare systemic disorder characterized by recurrent, widespread chondritis of the auricular, nasal, and tracheal cartilages. IgG4-related disease (IgG4-RD) is a systemic immune-mediated disease characterized by the infiltration of IgG4-bearing plasma ...

Last Updated: 11 Jul 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Relapsing polychondritis" returned 8 free, full-text review articles on human participants. First 3 results:

Relapsing polychondritis with encephalitis: a case report and literature review.
 

Author(s): Mizuho Nara, Atsushi Komatsuda, Masaru Togashi, Hideki Wakui

Journal: Intern. Med.. 2015 ;54(2):231-4.

 

We herein report the case of a 39-year-old man who developed bilateral auricular chondritis, conjunctivitis, and central neurological symptoms. He was diagnosed with encephalitis associated with relapsing polychondritis (RP) based on the findings of an ear cartilage biopsy, cerebrospinal ...

Last Updated: 6 Mar 2015

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[Airway involvement in relapsing polychondritis].
 

Author(s): Naoto Azuma

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2012 ;35(3):157-67.

 

Relapsing Polychondritis (RP) is an uncommon, chronic, and potentially life-threatening multisystem disorder characterized by recurrent inflammatory episodes affecting the cartilaginous tissues of the external ears, nose, peripheral joints, larynx and tracheobronchial tree, sometimes ...

Last Updated: 13 Jul 2012

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Cholestasis as the initial presentation of relapsing polychondritis.
 

Author(s): Maria da Graça Ferronato, Leonardo Jönck Staub, Renata Cristina Teixeira Pinto Viana, Lígia da Rosa, Maria Beatriz Cacese Shiozawa, Janaína L Narciso-Schiavon, Esther Buzaglo Dantas-Correa, Leonardo de Lucca Schiavon

Journal: Ann Hepatol. ;10(4):565-7.

 

Relapsing polychondritis is an immune-mediated disease associated with inflammation in cartilaginous structures and other tissues throughout the body, particularly the ears, nose, eyes, joints, and respiratory tract. Although association with other conditions is seen in about one-third ...

Last Updated: 13 Sep 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Physical Training in Patients With Relapsing Polychondritis
 

Status: Recruiting

Condition Summary: Physical Activity

 

Last Updated: 24 Mar 2017

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