Relapsing polychondritis

Common Name(s)

Relapsing polychondritis

Relapsing polychondritis is a condition that affects connective tissue, particularly cartilage. Cartilage is a tough but flexible tissue that covers the ends of your bones at a joint, and gives shape and support to other parts of your body. Early symptoms of relapsing polychondritis may include irritation, redness, and swelling (inflammation) of the ears, nose, and/or eye. A person may experience arthritis involving multiple joints as well.  Relapsing polychondritis may affect the inner ear, heart, and skin and can cause sensorineural deafness, vertigo, aortic valve regurgitation, mitral valve regurgitation, and aneurysms.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Relapsing polychondritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Relapsing polychondritis" returned 114 free, full-text research articles on human participants. First 3 results:

3-D printouts of the tracheobronchial tree generated from CT images as an aid to management in a case of tracheobronchial chondromalacia caused by relapsing polychondritis.
 

Author(s): Matthew David Tam, Stephen David Laycock, David Jayne, Judith Babar, Brendon Noble

Journal:

 

This report concerns a 67 year old male patient with known advanced relapsing polychondritis complicated by tracheobronchial chondromalacia who is increasingly symptomatic and therapeutic options such as tracheostomy and stenting procedures are being considered. The DICOM files from ...

Last Updated: 14 Jan 2014

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Relapsing polychondritis diagnosed by transbronchial needle aspiration and (18)F-fluorodeoxyglucose positron emission tomography/computed tomography.
 

Author(s): Tao Chen, Jun-Hong Jiang, Chun-Hua Ling, Cheng Ji, Bin Zhang, Jian-An Huang

Journal: Chin. Med. J.. 2013 Oct;126(20):3930.

 

Last Updated: 25 Oct 2013

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Laryngotracheal stenosis requiring emergency tracheostomy as the first manifestation of childhood-relapsing polychondritis.
 

Author(s): Izabel M Buscatti, Maria Fernanda A Giacomin, Marco Felipe C Silva, LĂșcia M A Campos, Adriana M E Sallum, Clovis A Silva

Journal: Acta Reumatol Port. ;38(3):208-11.

 

Relapsing polychondritis is a rare childhood disorder of unknown etiology, characterized by inflammatory, recurrent and destructive cartilage lesions. The chondritis could be widespread and involves generally laryngeal and auricular hyaline cartilages. We described a 9 years and 4 ...

Last Updated: 23 Oct 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Relapsing polychondritis" returned 4 free, full-text review articles on human participants. First 3 results:

[Airway involvement in relapsing polychondritis].
 

Author(s): Naoto Azuma

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2012 ;35(3):157-67.

 

Relapsing Polychondritis (RP) is an uncommon, chronic, and potentially life-threatening multisystem disorder characterized by recurrent inflammatory episodes affecting the cartilaginous tissues of the external ears, nose, peripheral joints, larynx and tracheobronchial tree, sometimes ...

Last Updated: 13 Jul 2012

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[Manifestations mimicking relapsing polychondritis in a patient with microscopic polyangiitis].
 

Author(s): Hiroe Ogawa, Eiko Nishi, Hideto Kameda, Koichi Amano, Tsutomu Takeuchi

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2005 Apr;28(2):104-8.

 

Microscopic polyangiitis (MPA) is a systemic disorder characterized by inflammation of small vessels mainly affecting the kidneys and lungs. We describe a 72-year-old woman who developed multiple cartilage involvements as well as major manifestations of MPA. The left ear biopsy demonstrated ...

Last Updated: 2 May 2005

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Cartilage-specific autoimmunity in animal models and clinical aspects in patients - focus on relapsing polychondritis.
 

Author(s): Ann-Sofie Hansson, Rikard Holmdahl

Journal: Arthritis Res.. 2002 ;4(5):296-301.

 

Relapsing polychondritis is an autoimmune disease in which an inappropriate immune response destroys cartilage. Cartilage of the ears, larynx and nose rather than spine and joint cartilage is affected by a chronic relapsing and erosive inflammation. Several animal models for relapsing ...

Last Updated: 11 Sep 2002

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.