Recurrent respiratory papillomatosis

Common Name(s)

Recurrent respiratory papillomatosis

Recurrent respiratory papillomatosis (RRP) is a rare viral disease where tumors (papillomas) grow in the air passages leading from the nose and mouth into the lungs (respiratory tract). Although the tumors can grow anywhere in the respiratory tract, their presence in the larynx (voice box) causes the most frequent problems, a condition called laryngeal papillomatosis. The tumors may vary in size and grow very quickly. They often grow back even when removed. RRP is caused by two types of human papillomavirus (HPV), called HPV 6 and HPV 11.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Recurrent respiratory papillomatosis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Recurrent respiratory papillomatosis" returned 45 free, full-text research articles on human participants. First 3 results:

Differences in Transcriptional Activity of Human Papillomavirus Type 6 Molecular Variants in Recurrent Respiratory Papillomatosis.
 

Author(s): Caroline Measso do Bonfim, João Simão Sobrinho, Rodrigo Lacerda Nogueira, Daniel Salgado Kupper, Fabiana Cardoso Pereira Valera, Maurício Lacerda Nogueira, Luisa Lina Villa, Paula Rahal, Laura Sichero

Journal:

 

A significant proportion of recurrent respiratory papillomatosis (RRP) is caused by human papillomavirus type 6 (HPV-6). The long control region (LCR) contains cis-elements for regulation of transcription. Our aim was to characterize LCR HPV-6 variants in RRP cases, compare promoter ...

Last Updated: 8 Jul 2015

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A Case of the Intrapulmonary Spread of Recurrent Respiratory Papillomatosis With Malignant Transformation.
 

Author(s): Yang Xiao, Jun Wang, Demin Han, Lijing Ma

Journal: Am. J. Med. Sci.. 2015 Jul;350(1):55-7.

 

To describe an individual with recurrent respiratory papillomatosis that extended into the lung parenchyma and underwent malignant transformation and to discuss the characteristic imaging findings associated with this condition.

Last Updated: 1 Jul 2015

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Risk factors for aggressive recurrent respiratory papillomatosis in adults and juveniles.
 

Author(s): Turid Omland, Harriet Akre, Kathrine A Lie, Peter Jebsen, Leiv Sandvik, Kjell Brøndbo

Journal:

 

In this cohort study we examined whether gender, age at onset, observation time or human papillomavirus (HPV) genotype are risk factors for an aggressive clinical course in Recurrent Respiratory Papillomatosis (RRP). Clinical data from patient records comprised gender, age at onset, ...

Last Updated: 25 Nov 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Recurrent respiratory papillomatosis" returned 8 free, full-text review articles on human participants. First 3 results:

Surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis.
 

Author(s): Melissa Ameloti Gomes Avelino, Tallyta Campos Domingues Teixeira Zaiden, Raquel Oliveira Gomes

Journal: Braz J Otorhinolaryngol. ;79(5):636-42.

 

Recurrent respiratory papillomatosis or recurrent laryngeal papillomatosis is a disease of the larynx caused by human papilloma virus, characterized by verrucous epithelial lesions and usually recurring. In the literature there are several types of treatment, such as surgery to cold, ...

Last Updated: 21 Oct 2013

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Recurrent respiratory papillomatosis.
 

Author(s): Naren N Venkatesan, Harold S Pine, Michael P Underbrink

Journal: Otolaryngol. Clin. North Am.. 2012 Jun;45(3):671-94, viii-ix.

 

Recurrent respiratory papillomatosis (RRP) is a rare, benign disease with no known cure. RRP is caused by infection of the upper aerodigestive tract with the human papillomavirus (HPV). Passage through the birth canal is thought to be the initial transmission event, but infection ...

Last Updated: 16 May 2012

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Recurrent respiratory papillomatosis: a complex defect in immune responsiveness to human papillomavirus-6 and -11.
 

Author(s): Vincent R Bonagura, Lynda J Hatam, David W Rosenthal, James A de Voti, Fung Lam, Bettie M Steinberg, Allan L Abramson

Journal: APMIS. 2010 Jun;118(6-7):455-70.

 

Recurrent respiratory papillomatosis (RRP) is a rare disease of the larynx caused by infection with human papillomaviruses (HPV) -6 or -11, associated with significant morbidity and on occasion mortality. Here we summarize our current understanding of the permissive adaptive and innate ...

Last Updated: 17 Jun 2010

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Bevacizumab Versus Cidofovir for the Treatment of Recurrent Respiratory Papillomatosis
 

Status: Recruiting

Condition Summary: Recurrent Respiratory Papillomatosis

 

Last Updated: 25 Jul 2016

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4-valent HPV Vaccine to Treat Recurrent Respiratory Papillomatosis in Children
 

Status: Not yet recruiting

Condition Summary: Recurrent Respiratory Papillomatosis

 

Last Updated: 20 Nov 2013

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Safety Study of EF-022 in Adults With Recurrent Respiratory Papillomatosis (RRP)
 

Status: Not yet recruiting

Condition Summary: Recurrent Respiratory Papillomatosis

 

Last Updated: 2 Aug 2016

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