Recurrent respiratory papillomatosis

Common Name(s)

Recurrent respiratory papillomatosis

Recurrent respiratory papillomatosis (RRP) is a rare viral disease where tumors (papillomas) grow in the air passages leading from the nose and mouth into the lungs (respiratory tract). Although the tumors can grow anywhere in the respiratory tract, their presence in the larynx (voice box) causes the most frequent problems, a condition called laryngeal papillomatosis. The tumors may vary in size and grow very quickly. They often grow back even when removed. RRP is caused by two types of human papillomavirus (HPV), called HPV 6 and HPV 11.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Recurrent respiratory papillomatosis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Recurrent respiratory papillomatosis" returned 42 free, full-text research articles on human participants. First 3 results:

Immunological response to quadrivalent HPV vaccine in treatment of recurrent respiratory papillomatosis.
 

Author(s): Robin E A Tjon Pian Gi, Michel R M San Giorgi, Michael Pawlita, Angelika Michel, Bettien M van Hemel, Ed M D Schuuring, Edwin R van den Heuvel, Bernard F A M van der Laan, Frederik G Dikkers

Journal: Eur Arch Otorhinolaryngol. 2016 Oct;273(10):3231-6.

 

Aim of this study was to explore influence of the quadrivalent HPV vaccine (Gardasil(®)) on the immune status of recurrent respiratory papillomatosis (RRP) patients. In retrospective observational study, six RRP patients who received the quadrivalent HPV vaccine and whose HPV seroreactivity ...

Last Updated: 8 Sep 2016

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Differences in Transcriptional Activity of Human Papillomavirus Type 6 Molecular Variants in Recurrent Respiratory Papillomatosis.
 

Author(s): Caroline Measso do Bonfim, João Simão Sobrinho, Rodrigo Lacerda Nogueira, Daniel Salgado Kupper, Fabiana Cardoso Pereira Valera, Maurício Lacerda Nogueira, Luisa Lina Villa, Paula Rahal, Laura Sichero

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A significant proportion of recurrent respiratory papillomatosis (RRP) is caused by human papillomavirus type 6 (HPV-6). The long control region (LCR) contains cis-elements for regulation of transcription. Our aim was to characterize LCR HPV-6 variants in RRP cases, compare promoter ...

Last Updated: 8 Jul 2015

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A Case of the Intrapulmonary Spread of Recurrent Respiratory Papillomatosis With Malignant Transformation.
 

Author(s): Yang Xiao, Jun Wang, Demin Han, Lijing Ma

Journal: Am. J. Med. Sci.. 2015 Jul;350(1):55-7.

 

To describe an individual with recurrent respiratory papillomatosis that extended into the lung parenchyma and underwent malignant transformation and to discuss the characteristic imaging findings associated with this condition.

Last Updated: 1 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Recurrent respiratory papillomatosis" returned 10 free, full-text review articles on human participants. First 3 results:

Recurrent respiratory papillomatosis by HPV: review of the literature and update on the use of cidofovir.
 

Author(s): M Fusconi, M Grasso, A Greco, A Gallo, F Campo, M Remacle, R Turchetta, G Pagliuca, M DE Vincentiis

Journal: Acta Otorhinolaryngol Ital. 2014 Dec;34(6):375-81.

 

Recurrent respiratory papillomatosis is a viral induced disease characterised by exophytic epithelial lesions affecting the larynx. The problem with its treatment is the high recurrence of papilloma growth after surgical removal. The aim of our review is to analyse the actual use ...

Last Updated: 12 Mar 2015

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Surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis.
 

Author(s): Melissa Ameloti Gomes Avelino, Tallyta Campos Domingues Teixeira Zaiden, Raquel Oliveira Gomes

Journal: Braz J Otorhinolaryngol. ;79(5):636-42.

 

Recurrent respiratory papillomatosis or recurrent laryngeal papillomatosis is a disease of the larynx caused by human papilloma virus, characterized by verrucous epithelial lesions and usually recurring. In the literature there are several types of treatment, such as surgery to cold, ...

Last Updated: 21 Oct 2013

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Recurrent respiratory papillomatosis.
 

Author(s): Naren N Venkatesan, Harold S Pine, Michael P Underbrink

Journal: Otolaryngol. Clin. North Am.. 2012 Jun;45(3):671-94, viii-ix.

 

Recurrent respiratory papillomatosis (RRP) is a rare, benign disease with no known cure. RRP is caused by infection of the upper aerodigestive tract with the human papillomavirus (HPV). Passage through the birth canal is thought to be the initial transmission event, but infection ...

Last Updated: 16 May 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Bevacizumab Versus Cidofovir for the Treatment of Recurrent Respiratory Papillomatosis
 

Status: Recruiting

Condition Summary: Recurrent Respiratory Papillomatosis

 

Last Updated: 25 Jul 2016

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Safety Study of EF-022 in Adults With Recurrent Respiratory Papillomatosis (RRP)
 

Status: Not yet recruiting

Condition Summary: Recurrent Respiratory Papillomatosis

 

Last Updated: 2 Aug 2016

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Recurrent Respiratory Papillomatosis and Extraesophageal Reflux
 

Status: Recruiting

Condition Summary: Recurrent Respiratory Papillomatosis; Extra Oesophageal Reflux; Laryngeal Cyst

 

Last Updated: 2 Sep 2016

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