Recurrent respiratory papillomatosis

Common Name(s)

Recurrent respiratory papillomatosis

Recurrent respiratory papillomatosis (RRP) is a rare viral disease where tumors (papillomas) grow in the air passages leading from the nose and mouth into the lungs (respiratory tract). Although the tumors can grow anywhere in the respiratory tract, their presence in the larynx (voice box) causes the most frequent problems, a condition called laryngeal papillomatosis. The tumors may vary in size and grow very quickly. They often grow back even when removed. RRP is caused by two types of human papillomavirus (HPV), called HPV 6 and HPV 11.
 

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Condition Specific Organizations

Following organizations serve the condition "Recurrent respiratory papillomatosis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Recurrent respiratory papillomatosis" returned 32 free, full-text research articles on human participants. First 3 results:

Nucleotide and phylogenetic analysis of human papillomavirus types 6 and 11 isolated from recurrent respiratory papillomatosis in Brazil.
 

Author(s): Renata Prandini Adum de Matos, Laura Sichero, Isabela Mazuco Mansur, Caroline Measso do Bonfim, Cíntia Bittar, Rodrigo Lacerda Nogueira, Daniel Salgado Küpper, Fabiana Cardoso Pereira Valera, Maurício Lacerda Nogueira, Luisa Lina Villa, Marilia Freitas Calmon, Paula Rahal

Journal: Infect. Genet. Evol.. 2013 Jun;16():282-9.

 

There are few studies about the distribution of natural molecular variants of low-risk HPVs. Our aim was to evaluate the E6 early gene variability among HPV-6 and HPV-11 isolates detected in recurrent respiratory papillomatosis (RRP) samples obtained in a cohort of Brazilian patients. ...

Last Updated: 30 May 2013

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Identical human papillomavirus (HPV) genomic variants persist in recurrent respiratory papillomatosis for up to 22 years.
 

Author(s): Boštjan J Kocjan, Nina Gale, Irena Hočevar Boltežar, Katja Seme, Kristina Fujs Komloš, Lea Hošnjak, Polona J Maver, Mateja M Jelen, Irena Zupanič Pajnič, Jože Balažic, Mario Poljak

Journal: J. Infect. Dis.. 2013 Feb;207(4):583-7.

 

Seventy initial and 125 follow-up tissue specimens of laryngeal papillomas, obtained from 70 patients who had had recurrent respiratory papillomatosis for from 1-22 years, were investigated for the presence of human papillomavirus (HPV) DNA and HPV E5a, LCR and/or full-length genomic ...

Last Updated: 22 Jan 2013

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Lung squamous cell carcinoma arising in a patient with adult-onset recurrent respiratory papillomatosis.
 

Author(s): Yukihiro Hasegawa, Nobuyuki Sato, Hiromichi Niikawa, Satoshi Kamata, Seiya Sannohe, Hidekachi Kurotaki, Taisuke Sasaki, Akio Ebina

Journal: Jpn. J. Clin. Oncol.. 2013 Jan;43(1):78-82.

 

A 75-year-old male was admitted to our hospital in December 2011 with a mass in the right upper pulmonary lobe. He was incidentally diagnosed as having tracheal papillomas 10 years ago. Bronchoscopy revealed multiple polypoid papillomas in the dorsal lesion of the trachea. Polymerase ...

Last Updated: 28 Dec 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Recurrent respiratory papillomatosis" returned 8 free, full-text review articles on human participants. First 3 results:

Surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis.
 

Author(s): Melissa Ameloti Gomes Avelino, Tallyta Campos Domingues Teixeira Zaiden, Raquel Oliveira Gomes

Journal: Braz J Otorhinolaryngol. ;79(5):636-42.

 

Recurrent respiratory papillomatosis or recurrent laryngeal papillomatosis is a disease of the larynx caused by human papilloma virus, characterized by verrucous epithelial lesions and usually recurring. In the literature there are several types of treatment, such as surgery to cold, ...

Last Updated: 21 Oct 2013

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Recurrent respiratory papillomatosis.
 

Author(s): Naren N Venkatesan, Harold S Pine, Michael P Underbrink

Journal: Otolaryngol. Clin. North Am.. 2012 Jun;45(3):671-94, viii-ix.

 

Recurrent respiratory papillomatosis (RRP) is a rare, benign disease with no known cure. RRP is caused by infection of the upper aerodigestive tract with the human papillomavirus (HPV). Passage through the birth canal is thought to be the initial transmission event, but infection ...

Last Updated: 16 May 2012

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Recurrent respiratory papillomatosis: a complex defect in immune responsiveness to human papillomavirus-6 and -11.
 

Author(s): Vincent R Bonagura, Lynda J Hatam, David W Rosenthal, James A de Voti, Fung Lam, Bettie M Steinberg, Allan L Abramson

Journal: APMIS. 2010 Jun;118(6-7):455-70.

 

Recurrent respiratory papillomatosis (RRP) is a rare disease of the larynx caused by infection with human papillomaviruses (HPV) -6 or -11, associated with significant morbidity and on occasion mortality. Here we summarize our current understanding of the permissive adaptive and innate ...

Last Updated: 17 Jun 2010

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

4-valent HPV Vaccine to Treat Recurrent Respiratory Papillomatosis in Children
 

Status: Not yet recruiting

Condition Summary: Recurrent Respiratory Papillomatosis

 

Last Updated: 20 Nov 2013

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