Q fever

Common Name(s)

Q fever

Q fever is an infectious disease caused by the bacteria Coxiella burnetii. This disease is common in both animals and humans. Q fever is usually a mild disease that has flue like symptoms. However in rare cases when the infection returns, it can affect the heart, liver, brain or lungs. This type of the Q fever can lead to atypical pneumonia, hepatitis, and inflammation of inner lining of the heart. Common symptoms include, dry cough, fever, headache, joint pain, muscle pain. Other symptoms may include abdominal pain, rash, yellow skin, and shortness of breath. These symptoms often appear 20 days after the individual is expose to the bacteria. Q fever is usually treated with antibiotics like doxycycline. However when the infection lasts for more than 6 months, hydroxychloroquine might be also prescribed. This disease is more common in individuals who have contact with farm animals and raw dairy products. Talk with your doctor if you or your child has been diagnosed with Q fever to decide on the best treatment plan.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Q fever" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Q fever" returned 365 free, full-text research articles on human participants. First 3 results:

Granulomatous response to Coxiella burnetii, the agent of Q fever: the lessons from gene expression analysis.
 

Author(s): Delphine Faugaret, Amira Ben Amara, Julie Alingrin, Aurélie Daumas, Amélie Delaby, Catherine Lépolard, Didier Raoult, Julien Textoris, Jean-Louis Mège

Journal:

 

The formation of granulomas is associated with the resolution of Q fever, a zoonosis due to Coxiella burnetii; however the molecular mechanisms of granuloma formation remain poorly understood. We generated human granulomas with peripheral blood mononuclear cells (PBMCs) and beads ...

Last Updated: 8 Jan 2015

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Persistent high antibody titres against Coxiella burnetii after acute Q fever not explained by continued exposure to the source of infection: a case-control study.
 

Author(s): Rana Jajou, Cornelia Christina Henrica Wielders, Monique Leclercq, Jeroen van Leuken, Shahan Shamelian, Nicole Renders, Wim van der Hoek, Peter Schneeberger

Journal:

 

From 2007 to 2010, (the southern part of) the Netherlands experienced a large Q fever epidemic, with more than 4,000 reported symptomatic cases. Approximately 1 - 5% of the acute Q fever patients develop chronic Q fever. A high IgG antibody titre against phase I of Coxiella burnetii ...

Last Updated: 10 Mar 2015

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[Diagnosis and treatment of a patient with serous Q-fever, a case report].
 

Author(s): Shengyong Xu, Xuezhong Yu

Journal: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2014 Aug;26(8):595-6.

 

Last Updated: 15 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Q fever" returned 33 free, full-text review articles on human participants. First 3 results:

Q fever--selected issues.
 

Author(s): Agata Bielawska-Drózd, Piotr Cieślik, Tomasz Mirski, Michał Bartoszcze, Józef Piotr Knap, Jerzy Gaweł, Dorota Żakowska

Journal: Ann Agric Environ Med. 2013 ;20(2):222-32.

 

Q fever is an infectious disease of humans and animals caused by Gram-negative coccobacillus Coxiella burnetii, belonging to the Legionellales order, Coxiellaceae family. The presented study compares selected features of the bacteria genome, including chromosome and plasmids QpH1, ...

Last Updated: 18 Jun 2013

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Q fever in humans and farm animals in four European countries, 1982 to 2010.
 

Author(s): M Georgiev, A Afonso, H Neubauer, H Needham, R Thiery, A Rodolakis, Hj Roest, Kd Stark, Ja Stegeman, P Vellema, W van der Hoek, Sj More

Journal:

 

Q fever is a disease of humans, caused by Coxiella burnetii, and a large range of animals can be infected. This paper presents a review of the epidemiology of Q fever in humans and farm animals between 1982 and 2010, using case studies from four European countries (Bulgaria, France, ...

Last Updated: 1 Mar 2013

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Q fever and Mediterranean spotted fever associated with hemophagocytic syndrome: case study and literature review.
 

Author(s): M Lecronier, V Prendki, M Gerin, M Schneerson, A Renvoisé, C Larroche, M Ziol, O Fain, A Mekinian

Journal: Int. J. Infect. Dis.. 2013 Aug;17(8):e629-33.

 

Hemophagocytosis during Q fever (QF) and Mediterranean spotted fever (MSF) is rare and only a few cases have been reported. We aimed to investigate the characteristics, outcome, and treatment of QF/MSF-associated hemophagocytosis.

Last Updated: 17 Jun 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Immunogenicity of Q Fever Vaccine
 

Status: Not yet recruiting

Condition Summary: Q Fever

 

Last Updated: 30 Apr 2015

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A Screening Strategy for Q Fever Among Pregnant Women
 

Status: Recruiting

Condition Summary: Q Fever

 

Last Updated: 30 Jun 2010

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Laboratory Diagnosis of of Rickettsial and Rickettsia-like Diseases
 

Status: Recruiting

Condition Summary: Rickettsioses

 

Last Updated: 28 Sep 2012

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