Pulmonary Hypertension

Common Name(s)

Pulmonary Hypertension

Our mission is to find ways to prevent and cure pulmonary hypertension, and to provide hope for the pulmonary hypertension community through support, education, advocacy and awareness.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pulmonary Hypertension" for support, advocacy or research.

Caring Voice Coalition,Inc,

Caring Voice Coalition empowers patients who live with a life threatening chronic disease through comprehensive outreach programs and services aimed at financial, emotional and educational support. With a steadfast dedication to the organization’s set of core values, our knowledgeable, caring staff maintains our solid reputation as a dependable, responsive organization with a unique, holistic approach to improving the lives of our patients.

Last Updated: 17 Feb 2017

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Cure HHT (formerly HHT Foundation International, Inc.)

To find a cure for HHT while saving the lives and improving the well-being of individuals and families affected by HHT. To achieve this mission, the HHT Foundation will: fund research;educate families and physicians; provide linkages among people affected by HHT; collaborate with multidisciplinary HHT Treatment Centers worldwide; and advocate for and support those with HHT

Last Updated: 12 Feb 2016

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International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

Last Updated: 18 Apr 2010

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Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

Last Updated: 4 May 2015

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PHCentral

Pulmonary Hypertension Information, Support and Advocacy Since 1999

Last Updated: 19 Dec 2012

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Pulmonary Hypertension Association

The mission of the Pulmonary Hypertension Association (PHA) is to find ways to prevent and cure pulmonary hypertension, and to provide hope for the pulmonary hypertension community through support, education, advocacy and awareness.

Last Updated: 25 Oct 2012

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pulmonary Hypertension" for support, advocacy or research.

Caring Voice Coalition,Inc,

Caring Voice Coalition empowers patients who live with a life threatening chronic disease through comprehensive outreach programs and services aimed at financial, emotional and educational support. With a steadfast dedication to the organization’s set of core values, our knowledgeable, caring staff maintains our solid reputation as a dependable, responsive organization with a unique, holistic approach to improving the lives of our patients.

http://www.caringvoice.org

Last Updated: 17 Feb 2017

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Cure HHT (formerly HHT Foundation International, Inc.)

To find a cure for HHT while saving the lives and improving the well-being of individuals and families affected by HHT. To achieve this mission, the HHT Foundation will: fund research;educate families and physicians; provide linkages among people affected by HHT; collaborate with multidisciplinary HHT Treatment Centers worldwide; and advocate for and support those with HHT

http://www.curehht.org

Last Updated: 12 Feb 2016

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International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

http://www.sclero.org/

Last Updated: 18 Apr 2010

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Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

http://www.kidswithheart.org

Last Updated: 4 May 2015

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PHCentral

Pulmonary Hypertension Information, Support and Advocacy Since 1999

http://www.phcentral.org

Last Updated: 19 Dec 2012

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Pulmonary Hypertension Association

The mission of the Pulmonary Hypertension Association (PHA) is to find ways to prevent and cure pulmonary hypertension, and to provide hope for the pulmonary hypertension community through support, education, advocacy and awareness.

http://www.PHAssociation.org

Last Updated: 25 Oct 2012

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General Support Organizations

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General Resources

Recorded Webinars

The Cure HHT webinar series informs patients and physicians of the latest information in HHT treatment, medicine and research, but also builds and strengthens the HHT community. The live webinars feature physicians and scientists specializing in HHT,

Updated 22 Dec 2015

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HHT Treatment Centers

An HHT Center of Excellence is defined as a medical practice that facilitates the comprehensive coordination of care necessary for treating a patient who has HHT. The standard of care must either meet or exceed the guidelines recognized by the HHT Fo

Updated 22 Dec 2015

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HHT Fact Sheets and Brochures

We encourage you to print and share the HHT Fact Sheets & Brochures with your local physicians and family members.

Updated 22 Dec 2015

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HHT Patient Resources

Link to a variety of patient resources

Updated 22 Dec 2015

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Physician Resources for HHT

A variety of resources available to physicians treating HHT patients

Updated 22 Dec 2015

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HHT Scientific and Medical Publications

View a comprehensive list of articles that have been published in various scientific and medical journals with references relating to HHT research and discoveries along with updates on medical treatments and procedures.

Updated 22 Dec 2015

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HHT Publications by Topic

For more in depth reading on specific areas of interest, please review the following articles.

Updated 22 Dec 2015

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Glossary of HHT Terminology

Laypersons Guide to HHT Medical Terminology

Updated 22 Dec 2015

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Insurance Issues

Insurance Resources for HHT Patients

state insurance regulators, medicare, social security and disability benefits, how to file an insurance appeal

Uploaded by Advocacy Organization: Cure HHT (formerly HHT Foundation International, Inc.)

Updated 22 Dec 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pulmonary Hypertension" returned 3449 free, full-text research articles on human participants. First 3 results:

Pentaerythritol Tetranitrate In Vivo Treatment Improves Oxidative Stress and Vascular Dysfunction by Suppression of Endothelin-1 Signaling in Monocrotaline-Induced Pulmonary Hypertension.
 

Author(s): Sebastian Steven, Matthias Oelze, Moritz Brandt, Elisabeth Ullmann, Swenja Kröller-Schön, Tjebo Heeren, Lan P Tran, Steffen Daub, Mobin Dib, Dirk Stalleicken, Philip Wenzel, Thomas Münzel, Andreas Daiber

Journal: Oxid Med Cell Longev. 2017 ;2017():4353462.

 

Objective. Oxidative stress and endothelial dysfunction contribute to pulmonary arterial hypertension (PAH). The role of the nitrovasodilator pentaerythritol tetranitrate (PETN) on endothelial function and oxidative stress in PAH has not yet been defined. Methods and Results. PAH ...

Last Updated: 24 Mar 2017

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Implication of overexpression of dishevelled-associated activator of morphogenesis 1 (Daam-1) for the pathogenesis of human Idiopathic Pulmonary Arterial Hypertension (IPAH).
 

Author(s): Shun Yanai, Megumi Wakayama, Haruo Nakayama, Minoru Shinozaki, Hisayuki Tsukuma, Naobumi Tochigi, Tetsuo Nemoto, Tsutomu Saji, Kazutoshi Shibuya

Journal:

 

Idiopathic pulmonary arterial hypertension (IPAH) is a rare, fatal disease of unknown pathogenesis. Evidence from our recent study suggests that IPAH pathogenesis is related to upregulation of the Wnt/planar cell polarity (Wnt/PCP) pathway. We used microscopic observation and immunohistochemical ...

Last Updated: 14 Mar 2017

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The Correlation of Decreased Heart Rate Recovery and Chronotropic Incompetence with Exercise Capacity in Idiopathic Pulmonary Arterial Hypertension Patients.
 

Author(s): Changwei Wu, Jian Guo, Hui Liu, Bigyan Pudasaini, Wenlan Yang, Qinhua Zhao, Lan Wang, Jinming Liu

Journal: Biomed Res Int. 2017 ;2017():3415401.

 

We show by this study that a decrease in HRR1 in IPAH patients is associated with severe limitation of exercise capacity. HRR1 < 16 beats and CI just after completion of a CPET could be an indicator of poor prognosis.

Last Updated: 13 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pulmonary Hypertension" returned 674 free, full-text review articles on human participants. First 3 results:

A Review of Clinical Trial Endpoints of Patients with Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension and How They Relate to Patient Outcomes in the United States.
 

Author(s): Christine Divers, David Platt, Edward Wang, Jay Lin, Melissa Lingohr-Smith, Stephen C Mathai

Journal: J Manag Care Spec Pharm. 2017 Jan;23(1):92-104.

 

Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are subgroups of pulmonary hypertension and are considered rare diseases. Understanding how endpoints of clinical trials (and patient registry studies) of patients with PAH and CTEPH are ...

Last Updated: 27 Dec 2016

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Pregnancy in pulmonary arterial hypertension.
 

Author(s): Karen M Olsson, Richard Channick

Journal: Eur Respir Rev. 2016 Dec;25(142):431-437.

 

Despite advanced therapies, maternal mortality in women with pulmonary arterial hypertension (PAH) remains high in pregnancy and is especially high during the post-partum period. However, recent data indicates that morbidity and mortality during pregnancy and after birth have improved ...

Last Updated: 1 Dec 2016

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Beyond a single pathway: combination therapy in pulmonary arterial hypertension.
 

Author(s): Olivier Sitbon, Sean Gaine

Journal: Eur Respir Rev. 2016 Dec;25(142):408-417.

 

There is a strong rationale for combining therapies to simultaneously target three of the key pathways implicated in the pathogenesis of pulmonary arterial hypertension (PAH). Evidence to support this strategy is growing, and a number of studies have demonstrated that combination ...

Last Updated: 1 Dec 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Inhaled Nitrite in Subjects With Pulmonary Hypertension
 

Status: Recruiting

Condition Summary: Pulmonary Hypertension

 

Last Updated: 8 Dec 2016

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Diagnosis of Pulmonary Hypertension Using Cardiac Magnetic Resonance Images
 

Status: Recruiting

Condition Summary: Pulmonary Hypertension

 

Last Updated: 5 Apr 2017

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Database for Clinical and Anamnestic Data in Pulmonary Hypertension
 

Status: Recruiting

Condition Summary: Pulmonary Hypertension

 

Last Updated: 29 Nov 2016

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