Psoriasis

Common Name(s)

Psoriasis

Psoriasis is a skin disease that causes itchy or sore patches of thick, red skin with silvery scales. The skin on the elbows, knees, scalp, back, face, palms and feet is most often affected, but other parts of the body can be affected as well. A problem with the immune system causes psoriasis. In a process called cell turnover, skin cells that grow deep in the skin rise to the surface. Normally, this takes a month. In psoriasis, it happens in just days because the cells rise too fast. Although symptoms may come and go, for many, psoriasis is a lifelong condition. Infections, stress, dry skin and certain medications may make symptoms worse. Psoriasis usually occurs in adults. It sometimes runs in families. Treatments include creams, medications and light therapy.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Psoriasis" for support, advocacy or research.

National Psoriasis Foundation

Our mission is to find a cure for psoriasis and psoriatic arthritis and to eliminate their devastating effects through research, advocacy and education.

Last Updated: 15 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Psoriasis" for support, advocacy or research.

National Psoriasis Foundation

Our mission is to find a cure for psoriasis and psoriatic arthritis and to eliminate their devastating effects through research, advocacy and education.

http://www.psoriasis.org/

Last Updated: 15 Nov 2012

View Details

 

General Support Organizations

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General Resources

For scientists and medical professionals

Information about how to apply for National Psoriasis Foundation research grants and fellowships, our medical journal and other science-related materials for medical professionals.

Updated 15 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Psoriasis" returned 1385 free, full-text research articles on human participants. First 3 results:

Association of carotid intima-media thickness with leptin and apoliprotein b/apoliprotein a-I ratio reveals imminent predictors of subclinical atherosclerosis in psoriasis patients.
 

Author(s): Kumari Asha, Suman B Sharma, Archana Singal, Amitesh Aggarwal

Journal: Acta Medica (Hradec Kralove). 2014 ;57(1):21-7.

 

Psoriasis patients are often susceptible to cardiovascular diseases (CVD), including atherosclerosis. Traditional markers (biochemical and inflammatory) and diagnostic tools could detect occlusive but not subclinical atherosclerosis. Carotid intima-media thickness (CIMT), has recently ...

Last Updated: 10 Jul 2014

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Occurrence of psoriatic plaques on previous adalimumab injection sites during disease relapse in a patient with pustular psoriasis.
 

Author(s): Ting-Shun Wang, Tsen-Fang Tsai

Journal: J. Am. Acad. Dermatol.. 2014 Jul;71(1):e24-6.

 

Last Updated: 20 Jun 2014

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Cellular dissection of psoriasis for transcriptome analyses and the post-GWAS era.
 

Author(s): William R Swindell, Philip E Stuart, Mrinal K Sarkar, John J Voorhees, James T Elder, Andrew Johnston, Johann E Gudjonsson

Journal:

 

Genome-scale studies of psoriasis have been used to identify genes of potential relevance to disease mechanisms. For many identified genes, however, the cell type mediating disease activity is uncertain, which has limited our ability to design gene functional studies based on genomic findings.

Last Updated: 18 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Psoriasis" returned 221 free, full-text review articles on human participants. First 3 results:

[Psychological and biological background of the correlation between psoriasis and stress].
 

Author(s): L János Kálmán, Xénia Gonda, Lajos Kemény, Zoltán Rihmer, Zoltán Janka

Journal: Orv Hetil. 2014 Jun;155(24):939-48.

 

Stress is considered as a major contributor to the development and exacerbation of psoriasis by a significant proportion of patients and dermatologists. As both stressor and its effects are subject-dependent, thus extremely difficult to measure, our understanding of the exact role ...

Last Updated: 11 Jun 2014

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Management of psoriasis vulgaris and multiple sclerosis with fumaric acid.
 

Author(s): Spyridon Gkalpakiotis, Petr Arenberger, Petra Gkalpakioti, Eva Meluzinova, Devika Chandran, Monika Arenbergerova

Journal: J. Am. Acad. Dermatol.. 2014 Mar;70(3):e60-1.

 

Last Updated: 17 Feb 2014

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Psoriasis: female skin changes in various hormonal stages throughout life--puberty, pregnancy, and menopause.
 

Author(s): Romana Ceovic, Marko Mance, Zrinka Bukvic Mokos, Maja Svetec, Kresimir Kostovic, Daska Stulhofer Buzina

Journal: Biomed Res Int. 2013 ;2013():571912.

 

Psoriasis is one of the most prevalent immune mediated skin diseases worldwide. Despite the large prevalence in both men and women, the pathogenesis of this disease has not yet been fully clarified. Nowadays, it is believed that psoriasis is most likely a T helper Th1/Th17 induced ...

Last Updated: 24 Jan 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Determination of Lymphocyte JAM-C Expression in Patients With Psoriasis Vulgaris
 

Status: Recruiting

Condition Summary: Psoriasis; Psoriasis Vulgaris

 

Last Updated: 1 Feb 2010

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A Study to Evaluate the Safety and Efficacy of Adalimumab in Subjects With Chronic Plaque Psoriasis and Nail Psoriasis
 

Status: Recruiting

Condition Summary: Nail Psoriasis; Plaque Psoriasis

 

Last Updated: 21 Jul 2014

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A Study to Evaluate the Effectiveness of STELARA ™ (USTEKINUMAB) in the Treatment of Scalp Psoriasis
 

Status: Not yet recruiting

Condition Summary: Scalp Psoriasis; Plaque Psoriasis

 

Last Updated: 17 Jul 2012

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