Psoriasis

Common Name(s)

Psoriasis

Psoriasis is a skin disease that causes itchy or sore patches of thick, red skin with silvery scales. The skin on the elbows, knees, scalp, back, face, palms and feet is most often affected, but other parts of the body can be affected as well. A problem with the immune system causes psoriasis. In a process called cell turnover, skin cells that grow deep in the skin rise to the surface. Normally, this takes a month. In psoriasis, it happens in just days because the cells rise too fast. Although symptoms may come and go, for many, psoriasis is a lifelong condition. Infections, stress, dry skin and certain medications may make symptoms worse. Psoriasis usually occurs in adults. It sometimes runs in families. Treatments include creams, medications and light therapy.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Psoriasis" for support, advocacy or research.

National Psoriasis Foundation

Our mission is to find a cure for psoriasis and psoriatic arthritis and to eliminate their devastating effects through research, advocacy and education.

Last Updated: 15 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Psoriasis" for support, advocacy or research.

National Psoriasis Foundation

Our mission is to find a cure for psoriasis and psoriatic arthritis and to eliminate their devastating effects through research, advocacy and education.

http://www.psoriasis.org/

Last Updated: 15 Nov 2012

View Details

 

General Support Organizations

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General Resources

For scientists and medical professionals

Information about how to apply for National Psoriasis Foundation research grants and fellowships, our medical journal and other science-related materials for medical professionals.

Updated 15 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Psoriasis" returned 1371 free, full-text research articles on human participants. First 3 results:

Psoriasis in an HIV-infected woman on antiretroviral therapy.
 

Author(s): K Nwako-Mohamadi Maitseo, Vidushi Madan, Matthew N Tanko, Sandro Vento

Journal: Isr. Med. Assoc. J.. 2014 Apr;16(4):262-3.

 

Last Updated: 19 May 2014

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Focal segmental glomerulosclerosis associated with psoriasis.
 

Author(s): Subal Kumar Pradhan, Siba Shankar Beriha

Journal: Saudi J Kidney Dis Transpl. 2014 May;25(3):670-1.

 

Last Updated: 13 May 2014

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Guselkumab (an IL-23-specific mAb) demonstrates clinical and molecular response in patients with moderate-to-severe psoriasis.
 

Author(s): Howard Sofen, Stacy Smith, Robert T Matheson, Craig L Leonardi, Cesar Calderon, Carrie Brodmerkel, Katherine Li, Kim Campbell, Stanley J Marciniak, Yasmine Wasfi, Yuhua Wang, Philippe Szapary, James G Krueger

Journal: J. Allergy Clin. Immunol.. 2014 Apr;133(4):1032-40.

 

IL-23 expression is increased in psoriatic lesions and might regulate TH17 T-cell counts in patients with psoriasis.

Last Updated: 31 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Psoriasis" returned 221 free, full-text review articles on human participants. First 3 results:

[Psychological and biological background of the correlation between psoriasis and stress].
 

Author(s): L János Kálmán, Xénia Gonda, Lajos Kemény, Zoltán Rihmer, Zoltán Janka

Journal: Orv Hetil. 2014 Jun;155(24):939-48.

 

Stress is considered as a major contributor to the development and exacerbation of psoriasis by a significant proportion of patients and dermatologists. As both stressor and its effects are subject-dependent, thus extremely difficult to measure, our understanding of the exact role ...

Last Updated: 11 Jun 2014

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Management of psoriasis vulgaris and multiple sclerosis with fumaric acid.
 

Author(s): Spyridon Gkalpakiotis, Petr Arenberger, Petra Gkalpakioti, Eva Meluzinova, Devika Chandran, Monika Arenbergerova

Journal: J. Am. Acad. Dermatol.. 2014 Mar;70(3):e60-1.

 

Last Updated: 17 Feb 2014

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Psoriasis: female skin changes in various hormonal stages throughout life--puberty, pregnancy, and menopause.
 

Author(s): Romana Ceovic, Marko Mance, Zrinka Bukvic Mokos, Maja Svetec, Kresimir Kostovic, Daska Stulhofer Buzina

Journal: Biomed Res Int. 2013 ;2013():571912.

 

Psoriasis is one of the most prevalent immune mediated skin diseases worldwide. Despite the large prevalence in both men and women, the pathogenesis of this disease has not yet been fully clarified. Nowadays, it is believed that psoriasis is most likely a T helper Th1/Th17 induced ...

Last Updated: 24 Jan 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study to Evaluate the Safety and Efficacy of Adalimumab in Subjects With Chronic Plaque Psoriasis and Nail Psoriasis
 

Status: Recruiting

Condition Summary: Nail Psoriasis; Plaque Psoriasis

 

Last Updated: 21 Jul 2014

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Tofacitinib Ointment For Chronic Plaque Psoriasis
 

Status: Recruiting

Condition Summary: Psoriasis Vulgaris; Psoriasis

 

Last Updated: 29 Jul 2014

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Determination of Lymphocyte JAM-C Expression in Patients With Psoriasis Vulgaris
 

Status: Recruiting

Condition Summary: Psoriasis; Psoriasis Vulgaris

 

Last Updated: 1 Feb 2010

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