Psoriasis

Common Name(s)

Psoriasis

Psoriasis is a chronic (long-lasting) skin condition that causes cells to grow too quickly and results in red, scaly, and occasionally itchy patches on the skin. In normal skin, cells flake off from the surface and are replaced by new cells every four weeks. In people with psoriasis, new cells form and quickly move to the surface of the skin, forming thick patches (plaques) that typically appear on the elbows, knees, scalp, lower back, hands, or feet. These patches are usually dry and itchy. If scraped or picked, they can also bleed. In some cases of psoriasis, the areas where bones meet (joints) may also become swollen and stiff, which is called psoriatic arthritis. Psoriasis can be mild, causing small areas of rash, or severe, causing large areas of raised, red and loose plaques. Symptoms of psoriasis tend to come and go. Risk factors that can lead to the return of symptoms (flare-ups) include a dry climate, infections, stress, dry skin and certain medications.

The exact cause of psoriasis is unknown. However, it is thought to be an autoimmune disease, which means something causes the body’s immune system to attack itself, mistaking healthy cells for something foreign (from outside the body). It is believed that both genetic and environmental factors play a role in psoriasis. In order to diagnose psoriasis, your doctor will gather a medical history and perform a physical exam that focuses on the skin. Your doctor may also remove and examine a small piece of the affected skin (skin biopsy). There is no cure for psoriasis. However, there are many treatment options that may help control the symptoms. These include creams that can be applied to the surface of the skin (topical), oral medications, moisturizers, and light therapy. If you or your child have been diagnosed with psoriasis, talk with your doctor to decide which treatment option is best for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Psoriasis" for support, advocacy or research.

National Psoriasis Foundation

Our mission is to find a cure for psoriasis and psoriatic arthritis and to eliminate their devastating effects through research, advocacy and education.

Last Updated: 26 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Psoriasis" for support, advocacy or research.

National Psoriasis Foundation

Our mission is to find a cure for psoriasis and psoriatic arthritis and to eliminate their devastating effects through research, advocacy and education.

http://www.psoriasis.org/

Last Updated: 26 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
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General Resources

For scientists and medical professionals

Information about how to apply for National Psoriasis Foundation research grants and fellowships, our medical journal and other science-related materials for medical professionals.

Updated 15 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Psoriasis" returned 2369 free, full-text research articles on human participants. First 3 results:

Genotype combination contributes to psoriasis: An exhaustive algorithm perspective.
 

Author(s): Jinfa Dou, Huimin Guo, Fang Cheng, Hequn Huang, Liying Fu, Longnian Li, Chao Yang, Lei Ye, Leilei Wen, Yuyan Cheng, Lili Tang, Caihong Zhu, Zhengwei Zhu, Wenjun Wang, Yujun Sheng, Zaixing Wang, Shengxiu Liu, Xing Fan, Xianbo Zuo, Fusheng Zhou, Liangdan Sun, Xiaodong Zheng, Xuejun Zhang

Journal:

 

Researchers have learned that nearly all conditions and diseases have a genetic component. With the benefit of technological advances, many single-nucleotide polymorphisms (SNPs) have been found to be associated with the risk of complex disorders by using genome wide association studies ...

Last Updated: 11 Oct 2017

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Psychopathology and alexithymia in patients with psoriasis.
 

Author(s): Panagiota Korkoliakou, Vasiliki Efstathiou, Ioanna Giannopoulou, Christos Christodoulou, Anargyros Kouris, Dimitrios Rigopoulos, Athanasios Douzenis

Journal: An Bras Dermatol. ;92(4):510-515.

 

Psoriasis is a chronic, inflammatory, relapsing skin disease that has a psychosocial impact on the patients' life.

Last Updated: 27 Sep 2017

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The relationship between pruritus and clinical variables in patients with psoriasis.
 

Author(s): Anil Gulsel Bahali, Nahide Onsun, Ozlem Su, Dilek Biyik Ozkaya, Didem Dizman, Bugce Topukcu, Omer Uysal

Journal: An Bras Dermatol. ;92(4):470-473.

 

Pruritus is the most commonly occurring subjective symptom of dermatological disease. Published data on both prevalence and intensity of pruritus in psoriasis is limited.

Last Updated: 27 Sep 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Psoriasis" returned 383 free, full-text review articles on human participants. First 3 results:

Musculoskeletal ultrasonography for psoriatic arthritis and psoriasis patients: a systematic literature review.
 

Author(s): Alen Zabotti, Francesca Bandinelli, Alberto Batticciotto, Carlo Alberto Scirè, Annamaria Iagnocco, Garifallia Sakellariou,

Journal: Rheumatology (Oxford). 2017 Sep;56(9):1518-1532.

 

To systematically review the role of musculoskeletal US in patients suffering from PsA or psoriasis (Pso) in terms of prevalence, diagnosis, prognosis, monitoring and treatment.

Last Updated: 18 May 2017

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Quantitative Evaluation of Biologic Therapy Options for Psoriasis: A Systematic Review and Network Meta-Analysis.
 

Author(s): Zarif K Jabbar-Lopez, Zenas Z N Yiu, Victoria Ward, Lesley S Exton, M Firouz Mohd Mustapa, Eleanor Samarasekera, A David Burden, Ruth Murphy, Caroline M Owen, Richard Parslew, Vanessa Venning, Richard B Warren, Catherine H Smith

Journal: J. Invest. Dermatol.. 2017 Aug;137(8):1646-1654.

 

Multiple biologic treatments are licensed for psoriasis. The lack of head-to-head randomized controlled trials makes choosing between them difficult for patients, clinicians, and guideline developers. To establish their relative efficacy and tolerability, we searched MEDLINE, PubMed, ...

Last Updated: 1 May 2017

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Diagnosis and management of psoriasis.
 

Author(s): Whan B Kim, Dana Jerome, Jensen Yeung

Journal: Can Fam Physician. 2017 Apr;63(4):278-285.

 

To provide primary care clinicians with an up-to-date and practical overview of the diagnosis and management of psoriasis.

Last Updated: 13 Apr 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis
 

Status: Recruiting

Condition Summary: Psoriasis

 

Last Updated: 15 Sep 2017

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Efficacy and Safety Study of NP000888 in Subjects With Plaque and Nail Psoriasis
 

Status: Recruiting

Condition Summary: Psoriasis

 

Last Updated: 5 Sep 2017

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Videocapillaroscopy Assessment During Systemic Agent Therapy in Psoriasis
 

Status: Recruiting

Condition Summary: Psoriasis

 

Last Updated: 8 Sep 2017

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