Pseudomyxoma peritonei

Common Name(s)

Pseudomyxoma peritonei, Gelatinous ascites

Pseudomyxoma peritonei is a tumor that most often begins in the appendix.  As the tumor grows, tumor cells may spread into the peritoneal cavity and land on other nearby organs (such as the ovaries or intestines), sometimes forming additional tumors on the surface of these organs.   Pseudomyxoma peritonei is extremely unlikely to grow into these organs (to become invasive) or spread to more distant parts of the body (metastasize); therefore, it is not usually thought of as a malignant tumor.   It is rare, occurring in approximately two out of a million people, and women are affected two to three times more frequently than men.   The first symptoms of pseudomyxoma peritonei are an increase in the size of the belly, appendicitis, or the finding of a mass on the ovary during medical imaging tests.   
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pseudomyxoma peritonei" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pseudomyxoma peritonei" returned 95 free, full-text research articles on human participants. First 3 results:

[Ultrasonographic Features of Pseudomyxoma Peritonei and TheirComparison with Computed Tomographic Findings].
 

Author(s): Zhen-hong Qi, Sheng Cai, Jian-chu Li, Ke L, Yan Zhang, Meng-su Xiao, Na Su

Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2015 Aug;37(4):424-9.

 

To investigate the value of ultrasound in the diagnosis of pseudomyxoma peritonei (PMP) and summarize the ultrasonographic features of PMP by comparing with computed tomography (CT) findings.

Last Updated: 13 Nov 2015

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Pseudomyxoma peritonei extending to the lower extremity: a case report.
 

Author(s): Min Wook Joo, Yang-Guk Chung, Soo Young Hur, Ahwon Lee, Chan Kwon Jung, Won-Hee Jee, Jong Ho Kim

Journal:

 

Pseudomyxoma peritonei is characterized by mucinous ascites originating from a mucin-producing neoplasm; however, even the definition is still under debate. Tumor deposits extend and ultimately engulf the entire cavity, causing death from cachexia due to limited intestinal movement. ...

Last Updated: 18 Jul 2015

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Global gene expression in pseudomyxoma peritonei, with parallel development of two immortalized cell lines.
 

Author(s): Darren L Roberts, Sarah T O'Dwyer, Peter L Stern, Andrew G Renehan

Journal: Oncotarget. 2015 May;6(13):10786-800.

 

Pseudomyxoma peritonei (PMP) is a rare tumor of appendiceal origin. Treatment is major cytoreductive surgery but morbidity is high. PMP is considered chemo-resistant; its molecular biology is understudied; and presently, there is no platform for pre-clinical drug testing. Here, we ...

Last Updated: 1 Jun 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pseudomyxoma peritonei" returned 11 free, full-text review articles on human participants. First 3 results:

Mucinous epithelial neoplasms of the appendix and pseudomyxoma peritonei.
 

Author(s): Joseph Misdraji

Journal: Mod. Pathol.. 2015 Jan;28 Suppl 1():S67-79.

 

The classification of appendiceal mucinous neoplasms has been controversial, largely focused on a particular subset of low-grade mucinous tumors that, despite their innocuous appearance, can disseminate to the peritoneal cavity as pseudomyxoma peritonei (PMP). Recent WHO classification ...

Last Updated: 6 Jan 2015

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Secreted mucins in pseudomyxoma peritonei: pathophysiological significance and potential therapeutic prospects.
 

Author(s): Afshin Amini, Samar Masoumi-Moghaddam, Anahid Ehteda, David Lawson Morris

Journal:

 

Pseudomyxoma peritonei (PMP, ORPHA26790) is a clinical syndrome characterized by progressive dissemination of mucinous tumors and mucinous ascites in the abdomen and pelvis. PMP is a rare disease with an estimated incidence of 1-2 out of a million. Clinically, PMP usually presents ...

Last Updated: 4 Jun 2014

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Pathologic diagnosis, origin, and natural history of pseudomyxoma peritonei.
 

Author(s): Rebecca Buell-Gutbrod, Katja Gwin

Journal: Am Soc Clin Oncol Educ Book. 2013 ;():221-5.

 

Mucinous ascites and pools of mucin within the peritoneal cavity associated with neoplastic, mucinous epithelium are the characteristic features of pseudomyxoma peritonei (PMP). Clinically, PMP presents with abdominal distension and gelatinous ascites. In female patients, pelvic masses ...

Last Updated: 11 Dec 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Antibiotic Treatment and Long-term Outcomes of Patients With Pseudomyxoma Peritonei of Appendiceal Origin
 

Status: Recruiting

Condition Summary: Pseudomyxoma Peritonei; Appendiceal Neoplasms

 

Last Updated: 6 Oct 2015

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Gastrointestinal Microbiome Study of Appendiceal Cancer
 

Status: Not yet recruiting

Condition Summary: Pseudomyxoma Peritonei; Appendiceal Neoplasm; Cancer, Appendiceal

 

Last Updated: 4 Nov 2015

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Register With Patients in Which Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) Was Performed
 

Status: Recruiting

Condition Summary: Peritoneal Carcinomatosis; Pseudomyxoma Peritonei; Peritoneal Mesothelioma

 

Last Updated: 3 Jul 2015

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