Prune belly syndrome

Common Name(s)

Prune belly syndrome

Prune belly syndrome, also called Eagle-Barrett syndrome, is a condition characterized by three main features: (1) a lack of abdominal muscles, causing the skin on the belly area to wrinkle and appear "prune-like";  (2) undescended testicles in males; and (3) urinary tract problems. The incidence of prune belly syndrome (PBS) is 1 in 40,000 births; 95% of cases occur in boys. The severity of symptoms in infants with prune belly syndrome can vary greatly from child to child.  At one end of the spectrum, the condition may cause severe urogenital and pulmonary problems incompatible with life (resulting in stillbirth); at the other end of the spectrum, the condition may cause few, if any, urological abnormalities that require no treatment other than  undescended testicle repair in males. The cause of the condition is unknown.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Prune belly syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Prune belly syndrome" returned 21 free, full-text research articles on human participants. First 3 results:

A case of ultrasound-guided prenatal diagnosis of prune belly syndrome in Papua New Guinea--implications for management.
 

Author(s): Maria Ome, Regina Wangnapi, Nancy Hamura, Alexandra J Umbers, Peter Siba, Moses Laman, John Bolnga, Sheryle Rogerson, Holger W Unger

Journal:

 

Prune belly syndrome is a rare congenital malformation of unknown aetiology and is characterised by abnormalities of the urinary tract, a deficiency of abdominal musculature and bilateral cryptorchidism in males. We report a case of prune belly syndrome from Papua New Guinea, which ...

Last Updated: 15 May 2013

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The association between prune belly syndrome and dental anomalies: a case report.
 

Author(s): Maria Daniela Basso, Carla Oliveira Favretto, Robson Frederico Cunha

Journal:

 

Prune belly syndrome is a rare condition produced by an early mesodermal defect that causes abdominal abnormalities. However, the literature indicates that disturbances related to ectodermal development may also be present. This is the first case report in the literature to suggest ...

Last Updated: 6 Feb 2013

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Familial prune belly syndrome in a Nigerian family.
 

Author(s): Michael Okoeguale Ibadin, Ade Adeyekun Ademola, Gabriel Egberue Ofovwe

Journal: Saudi J Kidney Dis Transpl. 2012 Mar;23(2):338-42.

 

A case of Prune Belly Syndrome in an infant, the second in a middle class family with both parents in their late thirties, is presented because of its rarity. Constraints in the management are discussed and relevant literature reviewed. This is intended to awaken interest and sharpen ...

Last Updated: 2 Mar 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Prune belly syndrome" returned 1 free, full-text review articles on human participants. First 3 results:

Prenatal diagnosis of prune belly syndrome at 12 weeks of pregnancy: case report and review of the literature.
 

Author(s): T Hoshino, Y Ihara, H Shirane, T Ota

Journal: Ultrasound Obstet Gynecol. 1998 Nov;12(5):362-6.

 

We present a case of prune belly syndrome in a 12-week fetus whose previous anomaly scan at 10 weeks had been normal. The ultrasound diagnosis was based on the findings of a lower abdominal cystic echo caused by abnormal dilatation of the bladder. Termination was performed at 14 weeks ...

Last Updated: 21 Jan 1999

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Symptoms, Diagnosis, and Treatment

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