Prothrombin

Common Name(s)

Prothrombin

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Prothrombin" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Prothrombin" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Prothrombin" returned 599 free, full-text research articles on human participants. First 3 results:

Clinical utility of simultaneous measurement of alpha-fetoprotein and des-γ-carboxy prothrombin for diagnosis of patients with hepatocellular carcinoma in China: A multi-center case-controlled study of 1,153 subjects.
 

Author(s): Peipei Song, Xiaobin Feng, Yoshinori Inagaki, Tianqiang Song, Keming Zhang, Zhigang Wang, Shuguo Zheng, Kuansheng Ma, Qiang Li, Dalu Kong, Qiang Wu, Ti Zhang, Xin Zhao, Kiyoshi Hasegawa, Yasuhiko Sugawara, Norihiro Kokudo, Wei Tang,

Journal: Biosci Trends. 2014 Oct;8(5):266-73.

 

This study aimed to investigate the clinical utility of simultaneous measurement of alphafetoprotein (AFP) and des-γ-carboxy prothrombin (DCP) for hepatocellular carcinoma (HCC) diagnosis in Chinese patients predominantly caused by hepatitis B virus infection by a multi-center case-controlled ...

Last Updated: 10 Nov 2014

Go To URL
The benefit of prothrombin complex concentrate in decreasing neurological deterioration in patients with warfarin-associated intracerebral haemorrhage.
 

Author(s): W C Fong, W T Lo, Y W Ng, Y F Cheung, Gordon C K Wong, H F Ho, John H M Chan, Patrick C K Li

Journal: Hong Kong Med J. 2014 Dec;20(6):486-94.

 

To compare the outcomes of patients with warfarin-associated intracerebral haemorrhage given different treatments to reverse the effect of anticoagulation.

Last Updated: 9 Dec 2014

Go To URL
Association of apixaban therapy and prothrombin time in patients with atrial fibrillation.
 

Author(s): Masashi Kanemoto, Hiroko Kuhara, Toru Ueda, Takahiro Shinohara, Takamasa Oda, Fumiaki Nakao, Toshiaki Kamei, Yasuhiro Ikeda, Takashi Fujii

Journal: Circ. J.. 2014 ;78(11):2651-6.

 

This study evaluated whether measuring prothrombin time (PT) using particular reagents of interest predicted apixaban-associated anticoagulant activity in Japanese patients with non-valvular atrial fibrillation (NVAF). METHODS AND RESULTS: Two reagents, Shinplastin Excel S and ...

Last Updated: 24 Oct 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Prothrombin" returned 18 free, full-text review articles on human participants. First 3 results:

Management of the bleeding patient receiving new oral anticoagulants: a role for prothrombin complex concentrates.
 

Author(s): Lisa M Baumann Kreuziger, Joseph C Keenan, Colleen T Morton, David J Dries

Journal: Biomed Res Int. 2014 ;2014():583794.

 

Ease of dosing and simplicity of monitoring make new oral anticoagulants an attractive therapy in a growing range of clinical conditions. However, newer oral anticoagulants interact with the coagulation cascade in different ways than traditional warfarin therapy. Replacement of clotting ...

Last Updated: 19 Aug 2014

Go To URL
Clinical use and the Italian demand for prothrombin complex concentrates.
 

Author(s): Massimo Franchini, Giancarlo M Liumbruno, Monica Lanzoni, Fabio Candura, Stefania Vaglio, Samantha Profili, Giuseppina Facco, Gabriele Calizzani, Giuliano Grazzini

Journal: Blood Transfus. 2013 Sep;11 Suppl 4():s94-100.

 

Last Updated: 16 Dec 2013

Go To URL
Clinical use and the Italian demand for activated prothrombin complex and activated recombinant factor VII concentrates.
 

Author(s): Antonio Coppola, Annarita Tagliaferri, Gabriele Calizzani, Fabio Candura, Massimo Franchini, Carlo Ruosi, Giuliano Grazzini, Giovanni Di Minno

Journal: Blood Transfus. 2013 Sep;11 Suppl 4():s101-9.

 

Last Updated: 16 Dec 2013

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Prognostic Value of Prothrombin Fragments 1+2 for Pulmonary Embolism Incidence
 

Status: Not yet recruiting

Condition Summary: Pulmonary Disease, Chronic Obstructive; Disease Exacerbation; Pulmonary Embolism; Prothrombin Fragments

 

Last Updated: 1 Mar 2010

Go to URL
Reversal of Dabigatran With Prothrombin Complex Concentrate
 

Status: Recruiting

Condition Summary: Drug Action Reversal

 

Last Updated: 3 Jun 2015

Go to URL
Evaluating the Role of Thrombin in Saphenous Vein Graft Failure After Heart Bypass Surgery
 

Status: Recruiting

Condition Summary: Coronary Artery Bypass; Thrombosis

 

Last Updated: 8 May 2013

Go to URL