Prothrombin

Common Name(s)

Prothrombin

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Prothrombin" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Prothrombin" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Prothrombin" returned 588 free, full-text research articles on human participants. First 3 results:

A deep vein thrombosis caused by 20209C>T mutation in homozygosis of the prothrombin gene in a Caucasian patient.
 

Author(s): Silvia Izquierdo Alvarez, Eva Barrio Ollero, Francisco Miguel Llinares Sanjuan, Fabiola Lorente Martínez, María Teresa Calvo Martín

Journal:

 

Additional nucleotide substitutions in the 3'-untranslated region of prothrombin gene could explain some thrombotic events and also adverse pregnancy outcomes. We describe the first case of a homozygous 20209C>T mutation as the cause of deep vein thrombosis in a Spanish patient.

Last Updated: 14 Mar 2014

Go To URL
Mesenteric vein thrombosis in a patient heterozygous for factor V Leiden and G20210A prothrombin genotypes.
 

Author(s): Paras Karmacharya, Madan Raj Aryal, Anthony Donato

Journal: World J. Gastroenterol.. 2013 Nov;19(43):7813-5.

 

Mesenteric venous thrombosis (MVT) is a rare but life threatening form of bowel ischemia. It is implicated in 6%-9% of all cases of acute mesenteric ischemia. The proportion of patients with primary (or idiopathic) MVT varies from 0% to 49%, with a decrease in frequency secondary ...

Last Updated: 27 Nov 2013

Go To URL
Detection of antiphosphatidylserine/prothrombin antibodies and their potential diagnostic value.
 

Author(s): Polona Žigon, Saša Čučnik, Aleš Ambrožič, Tanja Kveder, Snežna Sodin Šemrl, Blaž Rozman, Borut Božič

Journal: Clin. Dev. Immunol.. 2013 ;2013():724592.

 

Antiprothrombin antibodies, measured with phosphatidylserine/prothrombin complex (aPS/PT) ELISA, have been reported to be associated with antiphospholipid syndrome (APS). They are currently being evaluated as a potential classification criterion for this autoimmune disease, characterized ...

Last Updated: 4 Nov 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Prothrombin" returned 17 free, full-text review articles on human participants. First 3 results:

Clinical use and the Italian demand for prothrombin complex concentrates.
 

Author(s): Massimo Franchini, Giancarlo M Liumbruno, Monica Lanzoni, Fabio Candura, Stefania Vaglio, Samantha Profili, Giuseppina Facco, Gabriele Calizzani, Giuliano Grazzini

Journal: Blood Transfus. 2013 Sep;11 Suppl 4():s94-100.

 

Last Updated: 16 Dec 2013

Go To URL
Clinical use and the Italian demand for activated prothrombin complex and activated recombinant factor VII concentrates.
 

Author(s): Antonio Coppola, Annarita Tagliaferri, Gabriele Calizzani, Fabio Candura, Massimo Franchini, Carlo Ruosi, Giuliano Grazzini, Giovanni Di Minno

Journal: Blood Transfus. 2013 Sep;11 Suppl 4():s101-9.

 

Last Updated: 16 Dec 2013

Go To URL
Long-term safety and efficacy of a pasteurized nanofiltrated prothrombin complex concentrate (Beriplex P/N): a pharmacovigilance study.
 

Author(s): A A Hanke, C Joch, K Görlinger

Journal: Br J Anaesth. 2013 May;110(5):764-72.

 

The rapid reversal of the effects of vitamin K antagonists is often required in cases of emergency surgery and life-threatening bleeding, or during bleeding associated with high morbidity and mortality such as intracranial haemorrhage. Increasingly, four-factor prothrombin complex ...

Last Updated: 19 Apr 2013

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Prognostic Value of Prothrombin Fragments 1+2 for Pulmonary Embolism Incidence
 

Status: Not yet recruiting

Condition Summary: Pulmonary Disease, Chronic Obstructive; Disease Exacerbation; Pulmonary Embolism; Prothrombin Fragments

 

Last Updated: 1 Mar 2010

Go to URL
Evaluating the Role of Thrombin in Saphenous Vein Graft Failure After Heart Bypass Surgery
 

Status: Recruiting

Condition Summary: Coronary Artery Bypass; Thrombosis

 

Last Updated: 8 May 2013

Go to URL

Last Updated: 14 Jun 2013

Go to URL