Prothrombin

Common Name(s)

Prothrombin

Description for this condition is not yet available.
 

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Condition Specific Organizations

Following organizations serve the condition "Prothrombin" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Prothrombin" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Prothrombin" returned 795 free, full-text research articles on human participants. First 3 results:

Prothrombin 3'end gene variants in isolated pulmonary embolism--the first report of FIIc.*64_*66del and FIIc.*303T>C variants.
 

Author(s): Maja Gvozdenov, Iva Pruner, Branko Tomic, Marijana Aradjanski, Nebojsa Antonijevic, Dragica Radojkovic, Valentina Djordjevic

Journal: Acta Cardiol. 2015 Apr;70(2):177-82.

 

Pulmonary embolism is usually considered as a complication of deep vein thrombosis, but there are still a number of cases of isolated pulmonary embolism. We aimed to investigate whether prothrombin 3'end gene variants might play a significant role in the pathogenesis of isolated pulmonary embolism.

Last Updated: 7 Jul 2015

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Lack of association between the prothrombin rs1799963 polymorphism and juvenile myoclonic epilepsy.
 

Author(s): João Paulo Lopes Born, Bruna Priscila dos Santos, Rodrigo Secolin, Fernando Tenório Gameleira, Tiago Gomes de Andrade, Luciana Cláudia Herculano Machado, Lívia Leite Góes Gitaí, Daniel Leite Góes Gitaí

Journal: Arq Neuropsiquiatr. 2015 Apr;73(4):289-92.

 

Juvenile myoclonic epilepsy (JME) accounts for 26% of generalized idiopathic epileptic syndromes. The highest levels of thrombin activity are closely involved in the development of neurological diseases, including epilepsy. The prothrombin c.20210G>A (rs1799963) variation, which alters ...

Last Updated: 21 May 2015

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Prognostic roles of preoperative α-fetoprotein and des-γ-carboxy prothrombin in hepatocellular carcinoma patients.
 

Author(s): Makoto Meguro, Toru Mizuguchi, Toshihiko Nishidate, Kenji Okita, Masayuki Ishii, Shigenori Ota, Tomomi Ueki, Emi Akizuki, Koichi Hirata

Journal: World J. Gastroenterol.. 2015 Apr;21(16):4933-45.

 

To clarify the utility of using des-γ-carboxy prothrombin (DCP) and α-fetoprotein (AFP) levels to predict the prognosis of hepatocellular carcinoma (HCC) in patients with hepatitis B virus (HBV) and the hepatitis C virus (HCV) infections.

Last Updated: 6 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Prothrombin" returned 23 free, full-text review articles on human participants. First 3 results:

Management of the bleeding patient receiving new oral anticoagulants: a role for prothrombin complex concentrates.
 

Author(s): Lisa M Baumann Kreuziger, Joseph C Keenan, Colleen T Morton, David J Dries

Journal: Biomed Res Int. 2014 ;2014():583794.

 

Ease of dosing and simplicity of monitoring make new oral anticoagulants an attractive therapy in a growing range of clinical conditions. However, newer oral anticoagulants interact with the coagulation cascade in different ways than traditional warfarin therapy. Replacement of clotting ...

Last Updated: 19 Aug 2014

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Clinical use and the Italian demand for prothrombin complex concentrates.
 

Author(s): Massimo Franchini, Giancarlo M Liumbruno, Monica Lanzoni, Fabio Candura, Stefania Vaglio, Samantha Profili, Giuseppina Facco, Gabriele Calizzani, Giuliano Grazzini

Journal: Blood Transfus. 2013 Sep;11 Suppl 4():s94-100.

 

Last Updated: 16 Dec 2013

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Clinical use and the Italian demand for activated prothrombin complex and activated recombinant factor VII concentrates.
 

Author(s): Antonio Coppola, Annarita Tagliaferri, Gabriele Calizzani, Fabio Candura, Massimo Franchini, Carlo Ruosi, Giuliano Grazzini, Giovanni Di Minno

Journal: Blood Transfus. 2013 Sep;11 Suppl 4():s101-9.

 

Last Updated: 16 Dec 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Prognostic Value of Prothrombin Fragments 1+2 for Pulmonary Embolism Incidence
 

Status: Not yet recruiting

Condition Summary: Pulmonary Disease, Chronic Obstructive; Disease Exacerbation; Pulmonary Embolism; Prothrombin Fragments

 

Last Updated: 1 Mar 2010

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PCC vs. FFP for Post Cardiopulmonary Bypass Coagulopathy and Bleeding
 

Status: Not yet recruiting

Condition Summary: Bleeding; Blood Loss, Surgical; Cardiovascular Surgical Procedures; Prothrombin Complex Concentrates; Fresh Frozen Plasma

 

Last Updated: 21 Sep 2015

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Reversal of Dabigatran With Prothrombin Complex Concentrate
 

Status: Recruiting

Condition Summary: Drug Action Reversal

 

Last Updated: 3 Jun 2015

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