Progressive hemifacial atrophy

Common Name(s)

Progressive hemifacial atrophy, Parry-Romberg Syndrome

Progressive hemifacial atrophy, or Parry-Romberg syndrome, is a condition that causes the breakdown of the skin and soft tissues of half of the face. Symptoms and severity vary from person to person. This condition tends to begin in childhood between the ages of 5 and 15 years, and worsen over the course of 2 to 10 years before stabilizing. In addition to the skin and soft tissues, the deterioration can involve the mouth and tongue, facial bones, eye socket, and eye. Other symptoms may include loss of facial hair, changes in skin color in affected areas, seizures, and episodes of severe facial pain. Treatment may involve reconstructive or microvascular surgery. Currently, the cause of the condition is unknown.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Progressive hemifacial atrophy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Progressive hemifacial atrophy" returned 5 free, full-text research articles on human participants. First 3 results:

Progressive hemifacial atrophy. A natural history study.
 

Author(s): M T Miller, M A Spencer

Journal: Trans Am Ophthalmol Soc. 1995 ;93():203-15; discussion 215-7.

 

To describe two very different natural history courses in 2 patients with hemifacial atrophy. Progressive hemifacial atrophy (Parry-Romberg syndrome, Romberg syndrome, PHA) is characterized by slowly progressive atrophy, frequently involving only one side of the face, primarily affecting ...

Last Updated: 22 Oct 1996

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Progressive hemifacial atrophy with agenesis of the head of the caudate nucleus.
 

Author(s): M Leäo, M L da Silva

Journal: J. Med. Genet.. 1994 Dec;31(12):969-71.

 

We describe a woman with right hemifacial atrophy, a high palate, partial left motor seizures, and mild atrophy of the left arm. CT scan showed asymmetrical lateral ventricles and MRI (magnetic resonance imaging) showed atrophy of the right cerebral hemisphere and agenesis of the ...

Last Updated: 20 Apr 1995

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Some observations on the aetiology of progressive hemifacial atrophy ("Parry-Romberg syndrome")
 

Author(s): A J Larner, D P Bennison

Journal: J. Neurol. Neurosurg. Psychiatr.. 1993 Sep;56(9):1035-6.

 

Last Updated: 26 Oct 1993

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Progressive hemifacial atrophy" returned 2 free, full-text review articles on human participants. First 3 results:

Autologous fat transplantation for the treatment of progressive hemifacial atrophy (Parry-Romberg syndrome: case report and review of medical literatute).
 

Author(s): Júlio César Garcia de Alencar, Sarah Hanna de Carvalho Andrade, Salustiano Gomes de Pinho Pessoa, Iana Silva Dias

Journal: An Bras Dermatol. ;86(4 Suppl 1):S85-8.

 

Parry-Romberg syndrome, also known as progressive hemifacial atrophy, is a rare disorder characterized by slow and progressive hemifacial atrophy. The treatment offered for the syndrome generally aims at improving aesthetics. Fat grafts, silicone injections or acrylic prosthesis are ...

Last Updated: 9 Nov 2011

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Progressive Hemifacial Atrophy--case report.
 

Author(s): Thiago Pastor da Silva Pinheiro, Camila Camarinha da Silva, Carolina Souza Limeira da Silveira, Patrícia Cristina Ereno Botelho, Maria das Graças Rodriguez Pinheiro, João de Jesus Viana Pinheiro

Journal:

 

Progressive Hemifacial Atrophy, also known as Parry-Romberg Syndrome, is an uncommon degenerative and poorly understood condition. It is characterized by a slow and progressive atrophy affecting one side of the face. The incidence and the cause of this alteration is unknown. A cerebral ...

Last Updated: 28 Feb 2006

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.