Progressive Aphasia

Common Name(s)

Progressive Aphasia

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Progressive Aphasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Progressive Aphasia" returned 173 free, full-text research articles on human participants. First 3 results:

Differentiating between subtypes of primary progressive aphasia and mild cognitive impairment on a modified version of the Frontal Behavioral Inventory.
 

Author(s): Donna C Tippett, Carol B Thompson, Cornelia Demsky, Rajani Sebastian, Amy Wright, Argye E Hillis

Journal:

 

Behavioral assessment has been investigated in frontotemporal lobar degeneration and Alzheimer's disease, but has not been explored extensively in subtypes of primary progressive aphasia (PPA). We explored the ability of a modified version of the Frontal Behavioral Inventory (FBI-mod) ...

Last Updated: 16 Aug 2017

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Data-driven classification of patients with primary progressive aphasia.
 

Author(s): Paul Hoffman, Seyed Ahmad Sajjadi, Karalyn Patterson, Peter J Nestor

Journal: Brain Lang. 2017 Nov;174():86-93.

 

Current diagnostic criteria classify primary progressive aphasia into three variants-semantic (sv), nonfluent (nfv) and logopenic (lv) PPA-though the adequacy of this scheme is debated. This study took a data-driven approach, applying k-means clustering to data from 43 PPA patients. ...

Last Updated: 13 Aug 2017

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Variable disruption of a syntactic processing network in primary progressive aphasia.
 

Author(s): Stephen M Wilson, Andrew T DeMarco, Maya L Henry, Benno Gesierich, Miranda Babiak, Bruce L Miller, Maria Luisa Gorno-Tempini

Journal: Brain. 2016 Nov;139(11):2994-3006.

 

Syntactic processing deficits are highly variable in individuals with primary progressive aphasia. Damage to left inferior frontal cortex has been associated with syntactic deficits in primary progressive aphasia in a number of structural and functional neuroimaging studies. However, ...

Last Updated: 24 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Progressive Aphasia" returned 17 free, full-text review articles on human participants. First 3 results:

Transcranial direct current stimulation in post stroke aphasia and primary progressive aphasia: Current knowledge and future clinical applications.
 

Author(s): Rajani Sebastian, Kyrana Tsapkini, Donna C Tippett

Journal: NeuroRehabilitation. 2016 Jun;39(1):141-52.

 

The application of transcranial direct current stimulation (tDCS) in chronic post stroke aphasia is documented in a substantial literature, and there is some new evidence that tDCS can augment favorable language outcomes in primary progressive aphasia. Anodal tDCS is most often applied ...

Last Updated: 20 Jul 2016

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Primary progressive aphasia and the evolving neurology of the language network.
 

Author(s): M-Marsel Mesulam, Emily J Rogalski, Christina Wieneke, Robert S Hurley, Changiz Geula, Eileen H Bigio, Cynthia K Thompson, Sandra Weintraub

Journal: Nat Rev Neurol. 2014 Oct;10(10):554-69.

 

Primary progressive aphasia (PPA) is caused by selective neurodegeneration of the language-dominant cerebral hemisphere; a language deficit initially arises as the only consequential impairment and remains predominant throughout most of the course of the disease. Agrammatic, logopenic ...

Last Updated: 6 Oct 2014

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Primary progressive aphasia and apraxia of speech.
 

Author(s): Youngsin Jung, Joseph R Duffy, Keith A Josephs

Journal: Semin Neurol. 2013 Sep;33(4):342-7.

 

Primary progressive aphasia is a neurodegenerative syndrome characterized by progressive language dysfunction. The majority of primary progressive aphasia cases can be classified into three subtypes: nonfluent/agrammatic, semantic, and logopenic variants. Each variant presents with ...

Last Updated: 15 Nov 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Language in Primary Progressive Aphasia
 

Status: Recruiting

Condition Summary: Primary Progressive Aphasia

 

Last Updated: 12 Sep 2017

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Assessment of Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia
 

Status: Recruiting

Condition Summary: Primary Progressive Aphasia

 

Last Updated: 11 Oct 2017

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tDCS Intervention in Primary Progressive Aphasia
 

Status: Recruiting

Condition Summary: Primary Progressive Aphasia; MCI; FTD

 

Last Updated: 4 May 2016

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