Progressive Aphasia

Common Name(s)

Progressive Aphasia

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Progressive Aphasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Progressive Aphasia" returned 129 free, full-text research articles on human participants. First 3 results:

Frontal white matter tracts sustaining speech production in primary progressive aphasia.
 

Author(s): Maria Luisa Mandelli, Eduardo Caverzasi, Richard J Binney, Maya L Henry, Iryna Lobach, Nikolas Block, Bagrat Amirbekian, Nina Dronkers, Bruce L Miller, Roland G Henry, Maria Luisa Gorno-Tempini

Journal: J. Neurosci.. 2014 Jul;34(29):9754-67.

 

In primary progressive aphasia (PPA), speech and language difficulties are caused by neurodegeneration of specific brain networks. In the nonfluent/agrammatic variant (nfvPPA), motor speech and grammatical deficits are associated with atrophy in a left fronto-insular-striatal network ...

Last Updated: 17 Jul 2014

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Logopenic and nonfluent variants of primary progressive aphasia are differentiated by acoustic measures of speech production.
 

Author(s): Kirrie J Ballard, Sharon Savage, Cristian E Leyton, Adam P Vogel, Michael Hornberger, John R Hodges

Journal:

 

Differentiation of logopenic (lvPPA) and nonfluent/agrammatic (nfvPPA) variants of Primary Progressive Aphasia is important yet remains challenging since it hinges on expert based evaluation of speech and language production. In this study acoustic measures of speech in conjunction ...

Last Updated: 3 Mar 2014

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Progranulin-associated PiB-negative logopenic primary progressive aphasia.
 

Author(s): Keith A Josephs, Joseph R Duffy, Edythe A Strand, Mary M Machulda, Prashanthi Vemuri, Matthew L Senjem, Ralph B Perkerson, Matthew C Baker, Val Lowe, Clifford R Jack, Rosa Rademakers, Jennifer L Whitwell

Journal: J. Neurol.. 2014 Mar;261(3):604-14.

 

The logopenic variant of primary progressive aphasia (lvPPA) strongly associates with Alzheimer's disease, but can also associate with frontotemporal lobar degeneration. We aimed to assess the frequency of lvPPA in patients with speech and language disorders without β-amyloid deposition, ...

Last Updated: 10 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Progressive Aphasia" returned 12 free, full-text review articles on human participants. First 3 results:

Primary progressive aphasia and apraxia of speech.
 

Author(s): Youngsin Jung, Joseph R Duffy, Keith A Josephs

Journal: Semin Neurol. 2013 Sep;33(4):342-7.

 

Primary progressive aphasia is a neurodegenerative syndrome characterized by progressive language dysfunction. The majority of primary progressive aphasia cases can be classified into three subtypes: nonfluent/agrammatic, semantic, and logopenic variants. Each variant presents with ...

Last Updated: 15 Nov 2013

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Behavioural interventions for enhancing life participation in behavioural variant frontotemporal dementia and primary progressive aphasia.
 

Author(s): Kathleen B Kortte, Emily J Rogalski

Journal: Int Rev Psychiatry. 2013 Apr;25(2):237-45.

 

Primary progressive aphasia (PPA) and behavioural-variant frontotemporal dementia (bvFTD) are clinical syndromes under the umbrella term 'frontotemporal dementia' (FTD) and are caused by a neurodegenerative disease with an onset most typically in the productive years of adulthood. ...

Last Updated: 24 Apr 2013

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Are there susceptibility factors for primary progressive aphasia?
 

Author(s): Emily Rogalski, Sandra Weintraub, M-Marsel Mesulam

Journal: Brain Lang. 2013 Nov;127(2):135-8.

 

The determinants of selective vulnerability in neurodegenerative diseases remain elusive. The asymmetric loss of neurons in primary progressive aphasia offers a unique setting for addressing this question. Although no factor can yet account for the selective vulnerability of the left ...

Last Updated: 25 Nov 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Language in Primary Progressive Aphasia
 

Status: Recruiting

Condition Summary: Primary Progressive Aphasia

 

Last Updated: 11 Feb 2015

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Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
 

Status: Recruiting

Condition Summary: FTLD; Progressive Supranuclear Palsy (PSP); Frontotemporal Dementia (FTD); Corticobasal Degeneration (CBD); PPA Syndrome; Behavioral Variant Frontotemporal Dementia (bvFTD); Semantic Variant Primary Progressive Aphasia (svPPA); Nonfluent Variant Primary Progressive Aphasia (nfvPPA); FTD With Amyotrophic Lateral Sclerosis (FTD/ALS); Amyotrophic Lateral Sclerosis (ALS); Oligosymptomatic PSP (oPSP); Corticobasal Syndrome (CBS)

 

Last Updated: 11 Feb 2015

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Tau Imaging in Young Onset Dementia
 

Status: Recruiting

Condition Summary: Alzheimer's Disease, Early Onset; Logopenic Progressive Aphasia; Posterior Cortical Atrophy (PCA)

 

Last Updated: 13 Nov 2014

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