Primary hyperoxaluria type 1
Common Name(s)
Primary hyperoxaluria type 1
Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Primary hyperoxaluria type 1" for support, advocacy or research.
To seek the cause, improve the clinical treatment and discover the cure of hyperoxaluria and oxalate stone disease and enhance the quality of life of patients and their families.
How do you compare to others with this condition?
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Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Primary hyperoxaluria type 1" for support, advocacy or research.
To seek the cause, improve the clinical treatment and discover the cure of hyperoxaluria and oxalate stone disease and enhance the quality of life of patients and their families.
http://www.ohf.org/Recommended Apps
Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.
Finding the right clinical trial for Primary hyperoxaluria type 1 can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Scientific Literature
Articles from the PubMed Database
Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Primary hyperoxaluria type 1" returned 45 free, full-text research articles on human participants.
First 3 results:
Journal: Mol. Ther.. 2016 Apr;24(4):770-8.
Primary hyperoxaluria type 1 (PH1) is an autosomal recessive, metabolic disorder caused by mutations of alanine-glyoxylate aminotransferase (AGT), a key hepatic enzyme in the detoxification of glyoxylate arising from multiple normal metabolic pathways to glycine. Accumulation of glyoxylate, ...
Journal: Exp Clin Transplant. 2015 Nov;13 Suppl 3():97-100.
Primary hyperoxaluria type 1 is an autosomal recessive disorder that is responsible for the overproduction of oxalate and has an incidence of 1 in 120 000 live births. Indications for combined liver and kidney transplant are still debated. However, combined liver and kidney transplant ...
Journal: Gene Ther.. 2016 Feb;23(2):129-34.
Primary hyperoxaluria type 1 (PH1) is an inborn error of liver metabolism due to deficiency of the peroxisomal enzyme alanine:glyoxylate aminotransferase (AGT), which catalyzes conversion of glyoxylate into glycine. AGT deficiency results in overproduction of oxalate that ultimately ...
To view other free, full-text articles on human participants, please click on the link below.
Reviews from the PubMed Database
Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Primary hyperoxaluria type 1" returned 3 free, full-text review articles on human participants.
First 3 results:
Journal: Acta Cardiol. 2007 Apr;62(2):202-6.
Primary hyperoxaluria type I (PH I) is a rare recessive autosomal disorder characterized by systemic calcium oxalate depositions, that results in renal failure and systemic oxalosis. We report a 38-year-old male with cardiac oxalosis, a severe complication of PHI, presenting with ...
Journal: Biochim. Biophys. Acta. 2006 Dec;1763(12):1776-84.
Primary hyperoxaluria type 1 (PH1) is an atypical peroxisomal disorder, as befits a deficiency of alanine:glyoxylate aminotransferase (AGT), which is itself an atypical peroxisomal enzyme. PH1 is characterized by excessive synthesis and excretion of the metabolic end-product oxalate ...
To view other free, full-text review articles on human participants, please click on the link below.
Symptoms, Diagnosis, and Treatment
https://ghr.nlm.nih.gov/gene/AGXT
https://ghr.nlm.nih.gov/gene/GRHPR
https://ghr.nlm.nih.gov/gene/HOGA1
https://ghr.nlm.nih.gov/condition/leukocyte-adhesion-deficiency-type-1
https://ghr.nlm.nih.gov/condition/distal-arthrogryposis-type-1
https://ghr.nlm.nih.gov/condition/atelosteogenesis-type-1
https://ghr.nlm.nih.gov/condition/neurofibromatosis-type-1
https://ghr.nlm.nih.gov/condition/optic-atrophy-type-1
https://ghr.nlm.nih.gov/condition/otopalatodigital-syndrome-type-1
https://ghr.nlm.nih.gov/condition/pseudohypoaldosteronism-type-1
https://ghr.nlm.nih.gov/condition/spinocerebellar-ataxia-type-1
https://ghr.nlm.nih.gov/condition/type-1-diabetes
https://ghr.nlm.nih.gov/condition/primary-myelofibrosis
https://ghr.nlm.nih.gov/condition/acute-necrotizing-encephalopathy-type-1
https://ghr.nlm.nih.gov/condition/primary-carnitine-deficiency
https://ghr.nlm.nih.gov/condition/primary-localized-cutaneous-amyloidosis
https://ghr.nlm.nih.gov/condition/autosomal-recessive-primary-microcephaly
https://ghr.nlm.nih.gov/condition/primary-sclerosing-cholangitis
https://ghr.nlm.nih.gov/condition/primary-coenzyme-q10-deficiency
Clinical Trial Information This information is provided by ClinicalTrials.gov
Condition Summary: Primary Hyperoxaluria Type 1 (PH1)
Condition Summary: Primary Hyperoxaluria
Finding the right clinical trial for Primary hyperoxaluria type 1 can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.