Primary effusion lymphoma

Common Name(s)

Primary effusion lymphoma

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Primary effusion lymphoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Primary effusion lymphoma" returned 117 free, full-text research articles on human participants. First 3 results:

Human herpesvirus 8 viral interleukin-6 signaling through gp130 promotes virus replication in primary effusion lymphoma and endothelial cells.
 

Author(s): Emily Cousins, Yang Gao, Gordon Sandford, John Nicholas

Journal: J. Virol.. 2014 Oct;88(20):12167-72.

 

The contributions of human herpesvirus 8 (HHV-8) viral interleukin-6 (vIL-6) to virus biology remain unclear. Here we examined the role of vIL-6/gp130 signaling in HHV-8 productive replication in primary effusion lymphoma and endothelial cells. Depletion and depletion-complementation ...

Last Updated: 23 Sep 2014

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Downregulation of IRF4 induces lytic reactivation of KSHV in primary effusion lymphoma cells.
 

Author(s): Adriana Forero, Kevin D McCormick, Frank J Jenkins, Saumendra N Sarkar

Journal: Virology. 2014 Jun;458-459():4-10.

 

Primary effusion lymphoma (PEL), associated with the latent infection by KSHV, constitutively expresses interferon-regulatory factor 4 (IRF4). We recently showed that IRF4 differentially regulates expression of cellular interferon-stimulated genes (ISGs) and viral genes (Forero et ...

Last Updated: 14 Jun 2014

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Systematic analysis of a xenograft mice model for KSHV+ primary effusion lymphoma (PEL).
 

Author(s): Lu Dai, Jimena Trillo-Tinoco, Lihua Bai, Baoli Kang, Zengguang Xu, Xiaofei Wen, Luis Del Valle, Zhiqiang Qin

Journal:

 

Kaposi's sarcoma-associated herpesvirus is the causative agent of primary effusion lymphoma (PEL), which arises preferentially in the setting of infection with human immunodeficiency virus (HIV). Even with standard cytotoxic chemotherapy, PEL continues to cause high mortality rates, ...

Last Updated: 3 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Primary effusion lymphoma" returned 9 free, full-text review articles on human participants. First 3 results:

Human herpesvirus-8: Kaposi sarcoma, multicentric Castleman disease, and primary effusion lymphoma.
 

Author(s): Lawrence D Kaplan

Journal: Hematology Am Soc Hematol Educ Program. 2013 ;2013():103-8.

 

Human herpesvirus 8 (HHV8) is a gamma herpesvirus associated with Kaposi sarcoma, multicentric Castleman disease, and primary effusion lymphoma, lymphoproliferative diseases that are most commonly observed in immunocompromised individuals. The viral genome expresses genes responsible ...

Last Updated: 9 Dec 2013

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Human herpesvirus 8-unrelated primary effusion lymphoma-like lymphoma: report of a rare case and review of 54 cases in the literature.
 

Author(s): William Wu, Wonita Youm, Sherif A Rezk, Xiaohui Zhao

Journal: Am. J. Clin. Pathol.. 2013 Aug;140(2):258-73.

 

To report a patient with primary effusion lymphoma who was negative for human herpesvirus-8 (HHV-8), human immunodeficiency virus, Epstein-Barr virus, hepatitis C virus, and hepatitis B virus, as well as review 54 reported cases of HHV-8-unrelated primary effusion lymphoma (PEL)-like ...

Last Updated: 30 Jul 2013

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Use of cidofovir for the treatment of HIV-negative human herpes virus-8-associated primary effusion lymphoma.
 

Author(s): Tamara K Moyo, Kristy L Richards, Blossom Damania

Journal: Clin Adv Hematol Oncol. 2010 May;8(5):372-4.

 

Last Updated: 16 Jun 2010

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Specimen Collections From Patients With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer
 

Status: Recruiting

Condition Summary: HIV; Kaposi's Sarcoma; Lymphomas; Multicentric Castleman's Disease; Primary Effusion Lymphoma

 

Last Updated: 22 Apr 2015

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Gene Therapy and Combination Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin Lymphoma
 

Status: Not yet recruiting

Condition Summary: AIDS-Related Burkitt Lymphoma; AIDS-Related Diffuse Large B-cell Lymphoma; AIDS-Related Plasmablastic Lymphoma; AIDS-Related Primary Effusion Lymphoma; HIV Infection

 

Last Updated: 22 Jul 2015

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Intravenous Chemotherapy or Oral Chemotherapy in Treating Patients With Previously Untreated Stage III-IV HIV-Associated Non-Hodgkin Lymphoma
 

Status: Not yet recruiting

Condition Summary: AIDS-related Diffuse Large Cell Lymphoma; AIDS-related Diffuse Mixed Cell Lymphoma; AIDS-related Diffuse Small Cleaved Cell Lymphoma; AIDS-related Immunoblastic Large Cell Lymphoma; AIDS-related Lymphoblastic Lymphoma; AIDS-related Peripheral/Systemic Lymphoma; AIDS-related Small Noncleaved Cell Lymphoma; Stage III AIDS-related Lymphoma; Stage IV AIDS-related Lymphoma

 

Last Updated: 7 May 2015

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