Primary aldosteronism

Common Name(s)

Primary aldosteronism, Conn's syndrome

Primary aldosteronism, also known as Conn's syndrome, is considered one of the most common causes of secondary hypertension or high blood pressure. Primary aldosteronism occurs when your body produces too much aldosterone, which is a hormone that controls the sodium and patassium levels in the blood. When too much aldosterone is produced, the result is too much salt (sodium) and too little potassium in the blood, which leads to hypertension. Conn's syndrome is more common in females than males and can occur at any age, but most commonly in people in their 30s and 40s. Symptoms may include muscle weakness, frequent urination, excessive thirst, or muscle twitching and cramps. Medical therapy is a good treatment option.

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Condition Specific Organizations

Following organizations serve the condition "Primary aldosteronism" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Primary aldosteronism" returned 224 free, full-text research articles on human participants. First 3 results:

Sleep quality in patients with primary aldosteronism.
 

Author(s): Franziska M Hanusch, Evelyn Fischer, Katharina Lang, Sven Diederich, Stephan Endres, Bruno Allolio, Felix Beuschlein, Martin Reincke, Marcus Quinkler

Journal: Hormones (Athens). ;13(1):57-64.

 

In subjects at high risk for sleep apnea (SA), aldosterone concentrations correlate with severity of SA and primary aldosteronism (PA) is very often diagnosed. Patients with PA show a high prevalence of SA. Treatment of PA either by adrenalectomy (ADX) or mineralocorticoid receptor ...

Last Updated: 11 Apr 2014

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Twenty-four-hour urinary aldosterone predicts inappropriate left ventricular mass index in patients with primary aldosteronism.
 

Author(s): Chi-Sheng Hung, Yi-Lwun Ho, Yi-Yao Chang, Vin-Cent Wu, Xue-Ming Wu, Jen-Kuang Lee, Shih-Chieh Chueh, Yen-Hung Lin, Yuan-Shian Changh, Shao-Yu Yang, Ya-Hui Hu, Ming-Jai Sui, Ming-Fong Chen, Kwan-Dun Wu

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Primary aldosteronism (PA) is associated with inappropriate left ventricular hypertrophy (LVH) in relation to a given gender and body size. There is no ideal parameter to predict the presence of LVH or inappropriate LVH in patients with PA. We investigate the performance of 24-hour ...

Last Updated: 24 Jan 2014

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[Subclinical Cushing's syndrome with primary aldosteronism with the developing symptom of complications : a case report].
 

Author(s): Yusuke Inagaki, Motohide Uemura, Wataru Nakata, Yasutomo Nakai, Hitoshi Takayama, Akira Tsujimura, Norio Nonomura, Tetsuhiro Kitamura, Michio Otsuki

Journal: Hinyokika Kiyo. 2013 Nov;59(11):719-22.

 

A 42-year-old female patient had been receiving medication for hypertension. Her symptoms worsened in 2007. A computed tomography image revealed a 2.5 cm round mass in the right adrenal gland. According to a careful examination, the patient was diagnosed with primary aldosteronism ...

Last Updated: 10 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Primary aldosteronism" returned 23 free, full-text review articles on human participants. First 3 results:

Endocrine and hypertensive disorders of potassium regulation: primary aldosteronism.
 

Author(s): I David Weiner

Journal: Semin. Nephrol.. 2013 May;33(3):265-76.

 

The identification of primary aldosteronism as a common cause of resistant hypertension is a significant advance in our ability to care for patients with hypertension. Primary aldosteronism is common, and when unrecognized is associated with an increased incidence of adverse cardiovascular ...

Last Updated: 19 Aug 2013

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Is there a role for Nuclear Medicine in diagnosis and management of patients with primary aldosteronism?
 

Author(s): Trifon J Spyridonidis, Dimitris J Apostolopoulos

Journal: Hell J Nucl Med. ;16(2):134-9.

 

Primary aldosteronism (PA) is the most common cause of secondary hypertension. The diagnosis of PA is of clinical importance for choosing the appropriate treatment, meaning, surgery for the unilateral disease, and inclusion of aldosterone antagonists in the antihypertensive treatment ...

Last Updated: 18 Jul 2013

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Primary aldosteronism: a common and important problem. A practical guide to the diagnosis and treatment.
 

Author(s): Janusz Myśliwiec, Maria Górska

Journal: Endokrynol Pol. 2012 ;63(4):324-36.

 

In view of the fact that primary aldosteronism (PA) is a problem that is more prevalent than previously thought and its diagnosis is of greater clinical significance than previously believed, the Endocrine Society has recently published recommendations on the diagnosis and management ...

Last Updated: 30 Aug 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Primary Aldosteronism in General Practice: Organ Damage, Epidemiology and Treatment
 

Status: Not yet recruiting

Condition Summary: Primary Aldosteronism; Primary Hyperaldosteronism

 

Last Updated: 23 Jul 2013

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Metabolic Syndrome and Insulin Resistance in Primary Aldosteronism
 

Status: Recruiting

Condition Summary: Primary Aldosteronism

 

Last Updated: 28 Nov 2007

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Last Updated: 28 Apr 2014

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