Premature aging

Common Name(s)

Premature aging

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Premature aging" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Premature aging" returned 46 free, full-text research articles on human participants. First 3 results:

Premature aging in telomerase-deficient zebrafish.
 

Author(s): Monique Anchelin, Francisca Alcaraz-Pérez, Carlos M Martínez, Manuel Bernabé-García, Victoriano Mulero, María L Cayuela

Journal: Dis Model Mech. 2013 Sep;6(5):1101-12.

 

The study of telomere biology is crucial to the understanding of aging and cancer. In the pursuit of greater knowledge in the field of human telomere biology, the mouse has been used extensively as a model. However, there are fundamental differences between mouse and human cells. ...

Last Updated: 18 Sep 2013

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LMNA-associated cardiocutaneous progeria: an inherited autosomal dominant premature aging syndrome with late onset.
 

Author(s): Megan S Kane, Mark E Lindsay, Daniel P Judge, Jemima Barrowman, Colette Ap Rhys, Lisa Simonson, Harry C Dietz, Susan Michaelis

Journal: Am. J. Med. Genet. A. 2013 Jul;161A(7):1599-611.

 

Hutchinson-Gilford Progeria Syndrome (HGPS) is a premature aging disorder caused by mutations in LMNA, which encodes the nuclear scaffold proteins lamin A and C. In HGPS and related progerias, processing of prelamin A is blocked at a critical step mediated by the zinc metalloprotease ...

Last Updated: 20 Jun 2013

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Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment.
 

Author(s): Ahmed F Salem, Mazhar Salim Al-Zoubi, Diana Whitaker-Menezes, Ubaldo E Martinez-Outschoorn, Rebecca Lamb, James Hulit, Anthony Howell, Ricardo Gandara, Marina Sartini, Ferruccio Galbiati, Generoso Bevilacqua, Federica Sotgia, Michael P Lisanti

Journal: Cell Cycle. 2013 Mar;12(5):818-25.

 

Cigarette smoke has been directly implicated in the disease pathogenesis of a plethora of different human cancer subtypes, including breast cancers. The prevailing view is that cigarette smoke acts as a mutagen and DNA damaging agent in normal epithelial cells, driving tumor initiation. ...

Last Updated: 5 Mar 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Premature aging" returned 12 free, full-text review articles on human participants. First 3 results:

The epidemiology of premature aging and associated comorbidities.
 

Author(s): Fabio Coppedè

Journal: Clin Interv Aging. 2013 ;8():1023-32.

 

Hutchinson-Gilford Progeria Syndrome and Werner syndrome, also known as childhood- and adulthood-progeria, respectively, represent two of the best characterized human progeroid diseases with clinical features mimicking physiological aging at an early age. The discovery of their genetic ...

Last Updated: 10 Sep 2013

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The endothelium abridges insulin resistance to premature aging.
 

Author(s): Angelo Avogaro, Saula Vigili de Kreutzenberg, Massimo Federici, Gian Paolo Fadini

Journal:

 

Last Updated: 6 Aug 2013

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NF-kB in premature aging.
 

Author(s): Fernando G Osorio, Carlos López-Otín, José M P Freije

Journal: Aging (Albany NY). 2012 Nov;4(11):726-7.

 

Last Updated: 13 Dec 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Premature Aging and Type 2 Diabetes Mellitus: an Increased Risk of Cardiomyopathy?
 

Status: Recruiting

Condition Summary: Type 2 Diabetes Mellitus

 

Last Updated: 17 Jan 2013

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