Premature aging

Common Name(s)

Premature aging

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Premature aging" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Premature aging" returned 59 free, full-text research articles on human participants. First 3 results:

Impact of Oxidative Stress in Premature Aging and Iron Overload in Hemodialysis Patients.
 

Author(s): Blanca Murillo-Ortiz, Joel Ramírez Emiliano, Wendy Ivett Hernández Vázquez, Sandra Martínez-Garza, Sergio Solorio-Meza, Froylán Albarrán-Tamayo, Edna Ramos-Rodríguez, Luis Benítez-Bribiesca

Journal: Oxid Med Cell Longev. 2016 ;2016():1578235.

 

Background. Increased oxidative stress is a well described feature of patients in hemodialysis. Their need for multiple blood transfusions and supplemental iron causes a significant iron overload that has recently been associated with increased oxidation of polyunsaturated lipids ...

Last Updated: 1 Nov 2016

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Hypermethylation of FOXP3 Promoter and Premature Aging of the Immune System in Female Patients with Panic Disorder?
 

Author(s): Martina Prelog, Deborah Hilligardt, Christian A Schmidt, Grzegorz K Przybylski, Johannes Leierer, Giovanni Almanzar, Nady El Hajj, Klaus-Peter Lesch, Volker Arolt, Peter Zwanzger, Thomas Haaf, Katharina Domschke

Journal:

 

Immunological abnormalities associated with pathological conditions, such as higher infection rates, inflammatory diseases, cancer or cardiovascular events are common in patients with panic disorder. In the present study, T cell receptor excision circles (TRECs), Forkhead-Box-Protein ...

Last Updated: 1 Jul 2016

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Multiple Mechanisms Contribute to the Cell Growth Defects Imparted by Human Telomerase Insertion in Fingers Domain Mutations Associated with Premature Aging Diseases.
 

Author(s): Tsz Wai Chu, Deanna Elise MacNeil, Chantal Autexier

Journal: J. Biol. Chem.. 2016 Apr;291(16):8374-86.

 

Normal human stem cells rely on low levels of active telomerase to sustain their high replicative requirements. Deficiency in telomere maintenance mechanisms leads to the development of premature aging diseases, such as dyskeratosis congenita and aplastic anemia. Mutations in the ...

Last Updated: 30 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Premature aging" returned 17 free, full-text review articles on human participants. First 3 results:

Molecular insights into the premature aging disease progeria.
 

Author(s): Sandra Vidak, Roland Foisner

Journal: Histochem. Cell Biol.. 2016 Apr;145(4):401-17.

 

Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare premature aging disease presenting many features resembling the normal aging process. HGPS patients die before the age of 20 years due to cardiovascular problems and heart failure. HGPS is linked to mutations in the ...

Last Updated: 17 Mar 2016

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Skin Disease in Laminopathy-Associated Premature Aging.
 

Author(s): Tomás McKenna, Agustín Sola Carvajal, Maria Eriksson

Journal: J. Invest. Dermatol.. 2015 Nov;135(11):2577-83.

 

The nuclear lamina, a protein network located under the nuclear membrane, has during the past decade found increasing interest due to its significant involvement in a range of genetic diseases, including the segmental premature aging syndromes Hutchinson-Gilford progeria syndrome, ...

Last Updated: 9 Nov 2015

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SIRTain regulators of premature senescence and accelerated aging.
 

Author(s): Shrestha Ghosh, Zhongjun Zhou

Journal: Protein Cell. 2015 May;6(5):322-33.

 

The sirtuin proteins constitute class III histone deacetylases (HDACs). These evolutionarily conserved NAD(+)-dependent enzymes form an important component in a variety of cellular and biological processes with highly divergent as well as convergent roles in maintaining metabolic ...

Last Updated: 4 May 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Mental Ability Challenge Study in Adults With and Without HIV
 

Status: Recruiting

Condition Summary: HIV-1-infection; Aging, Premature; Cognitive Impairment; Memory Impairment; HIV-Associated Cognitive Motor Complex

 

Last Updated: 4 Aug 2017

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Inovium Ovarian Rejuvenation Trials
 

Status: Recruiting

Condition Summary: Perimenopausal Disorder; Menopause; Menopause, Premature; Menopause Related Conditions; Menopause Premature Symptomatic; Menopause Premature Asymptomatic; Premature Ovarian Failure; Premature Ovarian Failure, Familial; Premature Ovarian Failure 2A; Premature Ovarian Failure 3; Premature Ovarian Failure 4; Premature Ovarian Failure 1; Premature Ovarian Failure 5; Premature Ovarian Failure 6; Premature Ovarian Failure 7; Premature Ovarian Failure 9; Premature Ovarian Failure 8; Infertility; Infertility, Female; Infertility Unexplained

 

Last Updated: 29 Jun 2017

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