Premature aging

Common Name(s)

Premature aging

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Premature aging" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Premature aging" returned 61 free, full-text research articles on human participants. First 3 results:

Aging with ING: a comparative study of different forms of stress induced premature senescence.
 

Author(s): Uma Karthika Rajarajacholan, Karl Riabowol

Journal: Oncotarget. 2015 Oct;6(33):34118-27.

 

Cell senescence contributes to organismal aging and is induced by telomere erosion and an ensuing DNA damage signal as cells reach the end of their replicative lifespan in vitro or in vivo. Stresses induced by oncogene or tumor suppressor hyperactivation, oxidative stress, ionizing ...

Last Updated: 10 Nov 2015

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Aging-related premature luteinization of granulosa cells is avoided by early oocyte retrieval.
 

Author(s): Yan-Guang Wu, David H Barad, Vitaly A Kushnir, Emanuela Lazzaroni, Qi Wang, David F Albertini, Norbert Gleicher

Journal: J. Endocrinol.. 2015 Sep;226(3):167-80.

 

Why IVF pregnancy rates decline sharply after age 43 is unknown. In this study, we compared granulosa cell (GC) function in young oocyte donors (n=31, ages 21-29), middle-aged (n=64, ages 30-37) and older infertile patients (n=41, ages 43-47). Gene expressions related to gonadotropin ...

Last Updated: 22 Aug 2015

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Metabolic Damage and Premature Thymus Aging Caused by Stromal Catalase Deficiency.
 

Author(s): Ann V Griffith, Thomas Venables, Jianjun Shi, Andrew Farr, Holly van Remmen, Luke Szweda, Mohammad Fallahi, Peter Rabinovitch, Howard T Petrie

Journal: Cell Rep. 2015 Aug;12(7):1071-9.

 

T lymphocytes are essential mediators of immunity that are produced by the thymus in proportion to its size. The thymus atrophies rapidly with age, resulting in progressive diminution of new T cell production. This decreased output is compensated by duplication of existing T cells, ...

Last Updated: 20 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Premature aging" returned 18 free, full-text review articles on human participants. First 3 results:

Molecular insights into the premature aging disease progeria.
 

Author(s): Sandra Vidak, Roland Foisner

Journal: Histochem. Cell Biol.. 2016 Apr;145(4):401-17.

 

Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare premature aging disease presenting many features resembling the normal aging process. HGPS patients die before the age of 20 years due to cardiovascular problems and heart failure. HGPS is linked to mutations in the ...

Last Updated: 17 Mar 2016

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Skin Disease in Laminopathy-Associated Premature Aging.
 

Author(s): Tomás McKenna, Agustín Sola Carvajal, Maria Eriksson

Journal: J. Invest. Dermatol.. 2015 Nov;135(11):2577-83.

 

The nuclear lamina, a protein network located under the nuclear membrane, has during the past decade found increasing interest due to its significant involvement in a range of genetic diseases, including the segmental premature aging syndromes Hutchinson-Gilford progeria syndrome, ...

Last Updated: 9 Nov 2015

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SIRTain regulators of premature senescence and accelerated aging.
 

Author(s): Shrestha Ghosh, Zhongjun Zhou

Journal: Protein Cell. 2015 May;6(5):322-33.

 

The sirtuin proteins constitute class III histone deacetylases (HDACs). These evolutionarily conserved NAD(+)-dependent enzymes form an important component in a variety of cellular and biological processes with highly divergent as well as convergent roles in maintaining metabolic ...

Last Updated: 4 May 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.