Preeclampsia

Common Name(s)

Preeclampsia

Preeclampsia is a disorder that only affects pregnant women. The condition is characterized by high blood pressure and protein in the urine after 20 weeks of pregnancy. Preeclampsia and related hypertensive disorders in pregnancy are seen in 5-8% of pregnancies. Symptoms of preeclampsia include swelling, sudden weight gain, problems with vision and severe headaches, though symptoms will differ depending on the patient and some women will exhibit no symptoms. Preeclampsia is a serious condition. The high blood pressure, if untreated, may damage the pregnant woman's kidneys, and potentially other organs such as the liver and brain. When preeclampsia damage causes seizures the condition is called "eclampsia." In addition to harming the pregnant woman, preeclampsia-eclampsia can harm the developing baby. With proper prenatal care, preeclampsia can be diagnosed early and treated. Preeclampsia is detected by measuring protein in the mother's urine, a sign of kidney damage. If the pregnancy is to term, or almost to term, labor is often induced or a cesarean section performed. If the pregnancy is still in its early or middle stages, medication, bed rest, and other treatments will often be prescribed to help control the mother's blood pressure and treat symptoms until the baby can be safely delivered. Once the baby is delivered, preeclampsia usually goes away very quickly. Risk factors for developing preeclampsia include women with chronic hypertension, who are obese, who are under 20 or over 40 years of age, who are pregnant with more than one baby, and who have preexisting health problems, such as diabetes. The cause of preeclampsia is unknown, but researchers have produced a number of theories about the condition. (See also Eclampsia and Gestational hypertension.)

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Preeclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 23 Oct 2014

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Sidelines National Support Network

Sidelines provides support, education, advocacy and resources to women and their families experiencing a complicated high-risk pregnancy or premature birth.

Last Updated: 4 Apr 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Preeclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 23 Oct 2014

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Sidelines National Support Network

Sidelines provides support, education, advocacy and resources to women and their families experiencing a complicated high-risk pregnancy or premature birth.

http://www.sidelines.org

Last Updated: 4 Apr 2013

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General Support Organizations

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General Resources

The Preeclampsia Registry

The Preeclampsia Registry is a "Living Database" bringing together those affected, their family members, and researchers to advance knowledge and discover preventions and treatments for preeclampsia, HELLP syndrome, and related hypertensive disorders

Updated 23 Oct 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Preeclampsia" returned 1044 free, full-text research articles on human participants. First 3 results:

Trend in admissions, clinical features and outcome of preeclampsia and eclampsia as seen from the intensive care unit of the Douala General Hospital, Cameroon.
 

Author(s): Eugene Belley Priso, Theophile Nana Njamen, Charlotte Nguefack Tchente, Albert Justin Kana, Tchuenkam Landry, Ulrich Flore Nyaga Tchawa, Romuald Hentchoya, Gerard Beyiha, Marie Patrice Halle, Leopold Aminde, Anastase Dzudie

Journal:

 

Hypertensive disorders in pregnancy (HDP) are a major cause of maternal morbidity and mortality. We aimed at determining the trends in admission, profiles and outcomes of women admitted for preeclampsia and eclampsia to an intensive care unit (ICU) in Cameroon.

Last Updated: 2 Nov 2015

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Posterior reversible encephalopathy syndrome in patient of severe preeclampsia with Hellp syndrome immediate postpartum.
 

Author(s): Moulay Abdellah Babahabib, Ibrahima Abdillahi, Farid Kassidi, Jaouad Kouach, Driss Moussaoui, Mohammed Dehayni

Journal:

 

Posterior reversible encephalopathy syndrome (PRES) is a rare clinico-neuroradiologic condition, not commonly reported in the literature. PRES is an uncommon complication of severe preeclampsia/eclampsia. We report the management of one patient with postpartum preeclampsia as an association ...

Last Updated: 25 Sep 2015

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Placental damages in preeclampsia - from ultrasound images to histopathological findings.
 

Author(s): C G Predoi, C Grigoriu, R Vladescu, A E Mihart

Journal: J Med Life. 2015 ;8 Spec Issue():62-5.

 

Preeclampsia is a unique pregnancy-related disease that affects 5-7% pregnancies worldwide. Placental architecture is modified in PE and eclampsia. Placental morphology and cellular arrangement are important for oxygen delivery from the mother to the fetus. Fetal growth and well-being ...

Last Updated: 14 Sep 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Preeclampsia" returned 161 free, full-text review articles on human participants. First 3 results:

Maternal Antioxidant Levels in Pregnancy and Risk of Preeclampsia and Small for Gestational Age Birth: A Systematic Review and Meta-Analysis.
 

Author(s): Jacqueline M Cohen, Margaret Beddaoui, Michael S Kramer, Robert W Platt, Olga Basso, Susan R Kahn

Journal:

 

Oxidative stress in preeclampsia and small for gestational age (SGA) birth suggests antioxidant supplementation could prevent these conditions. However, it remains unclear whether maternal antioxidant levels are systematically lower in these pregnancies.

Last Updated: 7 Aug 2015

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Preeclampsia: long-term consequences for vascular health.
 

Author(s): Lorena M Amaral, Mark W Cunningham, Denise C Cornelius, Babbette LaMarca

Journal:

 

Preeclampsia (PE) is a pregnancy-specific syndrome and one of the leading causes of preterm birth, neonatal and maternal morbidity and mortality. This disease is characterized by new onset hypertension usually in the third trimester of pregnancy and is sometimes associated with proteinuria, ...

Last Updated: 23 Jul 2015

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Low-Dose Aspirin for Preventing Preeclampsia and Its Complications: A Meta-Analysis.
 

Author(s): Ting-ting Xu, Fan Zhou, Chun-yan Deng, Gui-qiong Huang, Jin-ke Li, Xiao-dong Wang

Journal: J Clin Hypertens (Greenwich). 2015 Jul;17(7):567-73.

 

Low-dose aspirin (LDA) is thought to prevent preeclampsia in high-risk pregnancy, but it is not universally used out of concern for its efficacy and safety. The authors meta-analyzed 29 randomized controlled trials (RCTs) to evaluate LDA for preventing preeclampsia and its complications. ...

Last Updated: 3 Jul 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Preeclampsia Registry
 

Status: Recruiting

Condition Summary: Preeclampsia; Eclampsia; HELLP Syndrome; Toxemia; Hypertensive Disorder of Pregnancy

 

Last Updated: 22 Oct 2015

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First-trimester Prediction of Preeclampsia
 

Status: Recruiting

Condition Summary: Preeclampsia; Severe Preeclampsia; Fetal Growth Restriction; Preterm Birth

 

Last Updated: 16 Feb 2015

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Influence of Conditional Workout Postpartum on Arterial Stiffness Among Women With Status After Preeclampsia, Superimposed Preeclampsia or HELLP-syndrome
 

Status: Recruiting

Condition Summary: Preeclampsia; Superimposed Preeclampsia; HELLP Syndrome

 

Last Updated: 25 Apr 2016

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