Preeclampsia

Common Name(s)

Preeclampsia

Preeclampsia is a disorder that only affects pregnant women. The condition is characterized by high blood pressure and protein in the urine after 20 weeks of pregnancy. Preeclampsia and related hypertensive disorders in pregnancy are seen in 5-8% of pregnancies. Symptoms of preeclampsia include swelling, sudden weight gain, problems with vision and severe headaches, though symptoms will differ depending on the patient and some women will exhibit no symptoms. Preeclampsia is a serious condition. The high blood pressure, if untreated, may damage the pregnant woman's kidneys, and potentially other organs such as the liver and brain. When preeclampsia damage causes seizures the condition is called "eclampsia." In addition to harming the pregnant woman, preeclampsia-eclampsia can harm the developing baby. With proper prenatal care, preeclampsia can be diagnosed early and treated. Preeclampsia is detected by measuring protein in the mother's urine, a sign of kidney damage. If the pregnancy is to term, or almost to term, labor is often induced or a cesarean section performed. If the pregnancy is still in its early or middle stages, medication, bed rest, and other treatments will often be prescribed to help control the mother's blood pressure and treat symptoms until the baby can be safely delivered. Once the baby is delivered, preeclampsia usually goes away very quickly. Risk factors for developing preeclampsia include women with chronic hypertension, who are obese, who are under 20 or over 40 years of age, who are pregnant with more than one baby, and who have preexisting health problems, such as diabetes. The cause of preeclampsia is unknown, but researchers have produced a number of theories about the condition. (See also Eclampsia and Gestational hypertension.)

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Preeclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 23 Oct 2014

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Sidelines National Support Network

Sidelines provides support, education, advocacy and resources to women and their families experiencing a complicated high-risk pregnancy or premature birth.

Last Updated: 4 Apr 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Preeclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 23 Oct 2014

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Sidelines National Support Network

Sidelines provides support, education, advocacy and resources to women and their families experiencing a complicated high-risk pregnancy or premature birth.

http://www.sidelines.org

Last Updated: 4 Apr 2013

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General Support Organizations

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General Resources

The Preeclampsia Registry

The Preeclampsia Registry is a "Living Database" bringing together those affected, their family members, and researchers to advance knowledge and discover preventions and treatments for preeclampsia, HELLP syndrome, and related hypertensive disorders

Updated 23 Oct 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Preeclampsia" returned 1086 free, full-text research articles on human participants. First 3 results:

Heart Rate Variability and Autonomic Modulations in Preeclampsia.
 

Author(s): Shaza M Musa, Ishag Adam, Mohamed F Lutfi

Journal:

 

Although the exact pathophysiology of preeclampsia is not well understood, autonomic nervous system imbalance is suggested as one of the main factors.

Last Updated: 5 Apr 2016

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Prognostic Value of Cardiovascular Disease Risk Factors Measured in the First-Trimester on the Severity of Preeclampsia.
 

Author(s): Po-Jen Cheng, Shang-Yu Huang, Sheng-Yuan Su, Ching-Hwa Hsiao, Hsiu-Huei Peng, Tao Duan

Journal: Medicine (Baltimore). 2016 Feb;95(5):e2653.

 

Recent studies have suggested that preeclampsia and cardiovascular disease may share common mechanisms. The purpose of this prospective nested case-controlled study was to characterize a variety of cardiovascular disease risk factors measured during the first trimester of pregnancy ...

Last Updated: 5 Feb 2016

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Effect of Placenta Previa on Preeclampsia.
 

Author(s): Hao Ying, Yi Lu, Yi-Nuo Dong, De-Fen Wang

Journal:

 

The correlation between gestational hypertension-preeclampsia (GH-PE) and placenta previa (PP) is controversial. Specifically, it is unknown whether placenta previa has any effect on the various types of preeclampsia (PE), and the role PP with concurrent placenta accreta (PA) play ...

Last Updated: 6 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Preeclampsia" returned 168 free, full-text review articles on human participants. First 3 results:

Immune Mechanisms Linking Obesity and Preeclampsia.
 

Author(s): Frank T Spradley, Ana C Palei, Joey P Granger

Journal:

 

Preeclampsia (PE) is characterized by hypertension occurring after the twentieth week of pregnancy. It is a significant contributor to maternal and perinatal morbidity and mortality in developing countries and its pervasiveness is increasing within developed countries including the ...

Last Updated: 17 Nov 2015

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The Relationship between Serum Zinc Level and Preeclampsia: A Meta-Analysis.
 

Author(s): Yue Ma, Xiaoli Shen, Dongfeng Zhang

Journal:

 

The association between serum zinc level and preeclampsia (PE) remains controversial. A systematic literature search was performed in PubMed, Web of Science and Embase for relevant available articles. The articles were limited to those in English from January 1990 to April 2015. Observational ...

Last Updated: 22 Sep 2015

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Regional changes of placental vascularization in preeclampsia: a review.
 

Author(s): Akriti S Sahay, Deepali P Sundrani, Sadhana R Joshi

Journal: IUBMB Life. 2015 Aug;67(8):619-25.

 

Preeclampsia is characterized by vascular dysfunction and results in maternal and fetal morbidity and mortality. The placenta plays a critical role in the growth and development of the fetus, and recent studies indicate that placental architecture, oxygen availability, and oxidative ...

Last Updated: 31 Aug 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Preeclampsia Registry
 

Status: Recruiting

Condition Summary: Preeclampsia; Eclampsia; HELLP Syndrome; Toxemia; Hypertensive Disorder of Pregnancy

 

Last Updated: 22 Oct 2015

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First-trimester Prediction of Preeclampsia
 

Status: Recruiting

Condition Summary: Preeclampsia; Severe Preeclampsia; Fetal Growth Restriction; Preterm Birth

 

Last Updated: 25 Jul 2016

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Influence of Conditional Workout Postpartum on Arterial Stiffness Among Women With Status After Preeclampsia, Superimposed Preeclampsia or HELLP-syndrome
 

Status: Recruiting

Condition Summary: Preeclampsia; Superimposed Preeclampsia; HELLP Syndrome

 

Last Updated: 25 Apr 2016

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