Preeclampsia

Common Name(s)

Preeclampsia

Preeclampsia is a disorder that only affects pregnant women. The condition is characterized by high blood pressure and protein in the urine after 20 weeks of pregnancy. Preeclampsia and related hypertensive disorders in pregnancy are seen in 5-8% of pregnancies. Symptoms of preeclampsia include swelling, sudden weight gain, problems with vision and severe headaches, though symptoms will differ depending on the patient and some women will exhibit no symptoms. Preeclampsia is a serious condition. The high blood pressure, if untreated, may damage the pregnant woman's kidneys, and potentially other organs such as the liver and brain. When preeclampsia damage causes seizures the condition is called "eclampsia." In addition to harming the pregnant woman, preeclampsia-eclampsia can harm the developing baby. With proper prenatal care, preeclampsia can be diagnosed early and treated. Preeclampsia is detected by measuring protein in the mother's urine, a sign of kidney damage. If the pregnancy is to term, or almost to term, labor is often induced or a cesarean section performed. If the pregnancy is still in its early or middle stages, medication, bed rest, and other treatments will often be prescribed to help control the mother's blood pressure and treat symptoms until the baby can be safely delivered. Once the baby is delivered, preeclampsia usually goes away very quickly. Risk factors for developing preeclampsia include women with chronic hypertension, who are obese, who are under 20 or over 40 years of age, who are pregnant with more than one baby, and who have preexisting health problems, such as diabetes. The cause of preeclampsia is unknown, but researchers have produced a number of theories about the condition. (See also Eclampsia and Gestational hypertension.)

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Preeclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 23 Oct 2014

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Sidelines National Support Network

Sidelines provides support, education, advocacy and resources to women and their families experiencing a complicated high-risk pregnancy or premature birth.

Last Updated: 4 Apr 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Preeclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

View Details
Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 23 Oct 2014

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Sidelines National Support Network

Sidelines provides support, education, advocacy and resources to women and their families experiencing a complicated high-risk pregnancy or premature birth.

http://www.sidelines.org

Last Updated: 4 Apr 2013

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General Support Organizations

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General Resources

The Preeclampsia Registry

The Preeclampsia Registry is a "Living Database" bringing together those affected, their family members, and researchers to advance knowledge and discover preventions and treatments for preeclampsia, HELLP syndrome, and related hypertensive disorders

Updated 23 Oct 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Preeclampsia" returned 1133 free, full-text research articles on human participants. First 3 results:

The sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia.
 

Author(s): Harald Zeisler, Martin Hund, Stefan Verlohren

Journal: N. Engl. J. Med.. 2016 May;374(18):1785-6.

 

Last Updated: 5 May 2016

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Preeclampsia and toxic metals: a case-control study in Kinshasa, DR Congo.
 

Author(s): Jean-Pierre Elongi Moyene, Hans Scheers, Barthélémy Tandu-Umba, Vincent Haufroid, Baudouin Buassa-Bu-Tsumbu, Fons Verdonck, Bernard Spitz, Benoit Nemery

Journal:

 

Preeclampsia is frequent in Kinshasa (Democratic Republic of Congo), especially during the dry season. We tested whether preeclampsia was associated with exposure to environmental metals.

Last Updated: 5 Apr 2016

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Heart Rate Variability and Autonomic Modulations in Preeclampsia.
 

Author(s): Shaza M Musa, Ishag Adam, Mohamed F Lutfi

Journal:

 

Although the exact pathophysiology of preeclampsia is not well understood, autonomic nervous system imbalance is suggested as one of the main factors.

Last Updated: 5 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Preeclampsia" returned 179 free, full-text review articles on human participants. First 3 results:

Prevalence of Preeclampsia and Eclampsia in Iran.
 

Author(s): Roghieh Kharaghani, Zahra Cheraghi, Batool Okhovat Esfahani, Zahra Mohammadian, Reyhaneh Sadat Nooreldinc

Journal: Arch Iran Med. 2016 Jan;19(1):64-71.

 

Several studies have been conducted to investigate the prevalence of preeclampsia and eclampsia in Iran. These studies have yielded different results. This meta-analysis was aimed to estimate the prevalence of preeclampsia and eclampsia in Iran.

Last Updated: 25 Dec 2015

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Immune Mechanisms Linking Obesity and Preeclampsia.
 

Author(s): Frank T Spradley, Ana C Palei, Joey P Granger

Journal:

 

Preeclampsia (PE) is characterized by hypertension occurring after the twentieth week of pregnancy. It is a significant contributor to maternal and perinatal morbidity and mortality in developing countries and its pervasiveness is increasing within developed countries including the ...

Last Updated: 17 Nov 2015

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Cigarette smoking during pregnancy and preeclampsia risk: a systematic review and meta-analysis of prospective studies.
 

Author(s): Jun Wei, Cai-Xia Liu, Ting-Ting Gong, Qi-Jun Wu, Lang Wu

Journal: Oncotarget. 2015 Dec;6(41):43667-78.

 

Although evidence from epidemiological studies evaluating the association between cigarette smoking during pregnancy and preeclampsia risk has been systematically reviewed, the findings have been out of date. To further clarify the relationship, we conducted this comprehensive meta-analysis ...

Last Updated: 6 Jan 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Prevalence of Antiphospholipid Antibodies Among Women With Preeclampsia
 

Status: Recruiting

Condition Summary: Preeclampsia

 

Last Updated: 18 Nov 2016

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Low Dose Aspirin in the Prevention of Preeclampsia in China
 

Status: Recruiting

Condition Summary: Preeclampsia

 

Last Updated: 10 Jun 2016

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Standard 24-hour Urine Protein vs Shorter Period for Diagnosis of Pre-eclampsia
 

Status: Recruiting

Condition Summary: Preeclampsia

 

Last Updated: 15 Aug 2016

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