Preeclampsia

Common Name(s)

Preeclampsia

Preeclampsia is a disorder that only effects pregnant women. The condition is characterized by high blood pressure and protein in the urine after 20 weeks of pregnancy, and is seen in 5-8% of pregnancies. Symptoms of preeclampsia include swelling, sudden weight gain, problems with vision and severe headaches, though symptoms will differ depending on the patient. With proper prenatal care, preeclampsia can be diagnosed early and treated. The only cure for preeclampsia is delivery of the baby, but if it is too early to safely deliver the baby the condition can be managed with bed rest, medications for high blood pressure or anti-seizure medications. If not treated, preeclampsia can turn into the dangerous condition eclampsia. The cause of preeclampsia is unknown, but researchers have produced a number of theories about the condition.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Preeclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

View Details
Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 20 May 2014

View Details
Sidelines National Support Network

Sidelines provides support, education, advocacy and resources to women and their families experiencing a complicated high-risk pregnancy or premature birth.

Last Updated: 4 Apr 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Preeclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

View Details
Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 20 May 2014

View Details
Sidelines National Support Network

Sidelines provides support, education, advocacy and resources to women and their families experiencing a complicated high-risk pregnancy or premature birth.

http://www.sidelines.org

Last Updated: 4 Apr 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Preeclampsia" returned 756 free, full-text research articles on human participants. First 3 results:

Hypertension after preeclampsia and relation to the C1114G polymorphism (rs4606) in RGS2: data from the Norwegian HUNT2 study.
 

Author(s): Anne Stine Kvehaugen, Øyvind Melien, Oddgeir L Holmen, Hannele Laivuori, Ralf Dechend, Anne Cathrine Staff

Journal:

 

Preeclampsia is associated with an increased risk of hypertension later in life. The regulator of G protein signaling 2 negatively regulates several vasoconstrictors. We recently demonstrated an association between preeclampsia and the CG or GG genotype of the C1114G polymorphism ...

Last Updated: 11 Mar 2014

Go To URL
Images in clinical medicine. Hypertensive retinopathy associated with preeclampsia.
 

Author(s): Hanan Handor, Rajae Daoudi

Journal: N. Engl. J. Med.. 2014 Feb;370(8):752.

 

Last Updated: 20 Feb 2014

Go To URL
Effect of folic acid supplementation in pregnancy on preeclampsia: the folic acid clinical trial study.
 

Author(s): Shi Wu Wen, Josee Champagne, Ruth Rennicks White, Doug Coyle, William Fraser, Graeme Smith, Dean Fergusson, Mark C Walker

Journal: J Pregnancy. 2013 ;2013():294312.

 

Preeclampsia (PE) is hypertension with proteinuria that develops during pregnancy and affects at least 5% of pregnancies. The Effect of Folic Acid Supplementation in Pregnancy on Preeclampsia: the Folic Acid Clinical Trial (FACT) aims to recruit 3,656 high risk women to evaluate a ...

Last Updated: 18 Dec 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Preeclampsia" returned 122 free, full-text review articles on human participants. First 3 results:

Pregnancy, parturition and preeclampsia in women of African ancestry.
 

Author(s): Annettee Nakimuli, Olympe Chazara, Josaphat Byamugisha, Alison M Elliott, Pontiano Kaleebu, Florence Mirembe, Ashley Moffett

Journal: Am. J. Obstet. Gynecol.. 2014 Jun;210(6):510-520.e1.

 

Maternal and associated neonatal mortality rates in sub-Saharan Africa remain unacceptably high. In Mulago Hospital (Kampala, Uganda), 2 major causes of maternal death are preeclampsia and obstructed labor and their complications, conditions occurring at the extremes of the birthweight ...

Last Updated: 2 Jun 2014

Go To URL
Angiogenic factors in preeclampsia: potential for diagnosis and treatment.
 

Author(s): Arvind Goel, Sarosh Rana

Journal: Curr. Opin. Nephrol. Hypertens.. 2013 Nov;22(6):643-50.

 

The review summarizes new observations of key roles for circulating angiogenic factors in diagnosing, managing, and treating preeclampsia.

Last Updated: 9 Oct 2013

Go To URL
Mixing nulliparous and multiparous women in randomised controlled trials of preeclampsia prevention is debatable: evidence from a systematic review.
 

Author(s): Emmanuel Simon, Agnès Caille, Franck Perrotin, Bruno Giraudeau

Journal:

 

Nulliparity is a major risk factor of preeclampsia investigated in numerous trials of its prevention.

Last Updated: 4 Jul 2013

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

First-trimester Prediction of Preeclampsia
 

Status: Not yet recruiting

Condition Summary: Early Onset Preeclampsia; Severe Preeclampsia; Fetal Growth Restriction; Preterm Birth

 

Last Updated: 11 Jul 2014

Go to URL
İs There a Relationship Between Severity of Preeclampsia and Maternal Heavy Metal Levels?
 

Status: Recruiting

Condition Summary: Mild Pre-eclampsia; Severe Preeclampsia

 

Last Updated: 4 Aug 2013

Go to URL
Vitamin D and Preeclampsia
 

Status: Recruiting

Condition Summary: Vitamin D Deficiency Defined as Serum 25OHD < 75 Nmol/l or 30ng/ml; Preeclampsia; Neonatal Hypercalcemia; Pregnancy

 

Last Updated: 25 Jun 2014

Go to URL