Preeclampsia

Common Name(s)

Preeclampsia

Preeclampsia is a disorder that only effects pregnant women. The condition is characterized by high blood pressure and protein in the urine after 20 weeks of pregnancy, and is seen in 5-8% of pregnancies. Symptoms of preeclampsia include swelling, sudden weight gain, problems with vision and severe headaches, though symptoms will differ depending on the patient. With proper prenatal care, preeclampsia can be diagnosed early and treated. The only cure for preeclampsia is delivery of the baby, but if it is too early to safely deliver the baby the condition can be managed with bed rest, medications for high blood pressure or anti-seizure medications. If not treated, preeclampsia can turn into the dangerous condition eclampsia. The cause of preeclampsia is unknown, but researchers have produced a number of theories about the condition.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Preeclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 20 May 2014

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Sidelines National Support Network

Sidelines provides support, education, advocacy and resources to women and their families experiencing a complicated high-risk pregnancy or premature birth.

Last Updated: 4 Apr 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Preeclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

View Details
Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 20 May 2014

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Sidelines National Support Network

Sidelines provides support, education, advocacy and resources to women and their families experiencing a complicated high-risk pregnancy or premature birth.

http://www.sidelines.org

Last Updated: 4 Apr 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Preeclampsia" returned 766 free, full-text research articles on human participants. First 3 results:

Hypertension after preeclampsia and relation to the C1114G polymorphism (rs4606) in RGS2: data from the Norwegian HUNT2 study.
 

Author(s): Anne Stine Kvehaugen, Øyvind Melien, Oddgeir L Holmen, Hannele Laivuori, Ralf Dechend, Anne Cathrine Staff

Journal:

 

Preeclampsia is associated with an increased risk of hypertension later in life. The regulator of G protein signaling 2 negatively regulates several vasoconstrictors. We recently demonstrated an association between preeclampsia and the CG or GG genotype of the C1114G polymorphism ...

Last Updated: 11 Mar 2014

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Images in clinical medicine. Hypertensive retinopathy associated with preeclampsia.
 

Author(s): Hanan Handor, Rajae Daoudi

Journal: N. Engl. J. Med.. 2014 Feb;370(8):752.

 

Last Updated: 20 Feb 2014

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Interbirth interval and history of previous preeclampsia: a case-control study among multiparous women.
 

Author(s): Arusyak Harutyunyan, Haroutune Armenian, Varduhi Petrosyan

Journal:

 

Preeclampsia is a disorder with a reported incidence of 2%-8% among all pregnancies, accounting for more than 50,000 deaths worldwide each year. In low- and middle- income countries maternal/perinatal morbidity and mortality associated with preeclampsia are high due to the lack of ...

Last Updated: 2 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Preeclampsia" returned 124 free, full-text review articles on human participants. First 3 results:

Pregnancy, parturition and preeclampsia in women of African ancestry.
 

Author(s): Annettee Nakimuli, Olympe Chazara, Josaphat Byamugisha, Alison M Elliott, Pontiano Kaleebu, Florence Mirembe, Ashley Moffett

Journal: Am. J. Obstet. Gynecol.. 2014 Jun;210(6):510-520.e1.

 

Maternal and associated neonatal mortality rates in sub-Saharan Africa remain unacceptably high. In Mulago Hospital (Kampala, Uganda), 2 major causes of maternal death are preeclampsia and obstructed labor and their complications, conditions occurring at the extremes of the birthweight ...

Last Updated: 2 Jun 2014

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Angiogenic factors in preeclampsia: potential for diagnosis and treatment.
 

Author(s): Arvind Goel, Sarosh Rana

Journal: Curr. Opin. Nephrol. Hypertens.. 2013 Nov;22(6):643-50.

 

The review summarizes new observations of key roles for circulating angiogenic factors in diagnosing, managing, and treating preeclampsia.

Last Updated: 9 Oct 2013

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New developments in the pathogenesis of preeclampsia.
 

Author(s): Mihran V Naljayan, S Ananth Karumanchi

Journal: Adv Chronic Kidney Dis. 2013 May;20(3):265-70.

 

Preeclampsia affects 3% to 5% of all pregnancies and is a major cause of maternal and perinatal morbidity and mortality worldwide. This disorder is characterized by a constellation of signs and symptoms, most notably new-onset hypertension and proteinuria during the last trimester ...

Last Updated: 9 Aug 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

First-trimester Prediction of Preeclampsia
 

Status: Not yet recruiting

Condition Summary: Early Onset Preeclampsia; Severe Preeclampsia; Fetal Growth Restriction; Preterm Birth

 

Last Updated: 11 Jul 2014

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İs There a Relationship Between Severity of Preeclampsia and Maternal Heavy Metal Levels?
 

Status: Recruiting

Condition Summary: Mild Pre-eclampsia; Severe Preeclampsia

 

Last Updated: 4 Aug 2013

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Vitamin D and Preeclampsia
 

Status: Recruiting

Condition Summary: Vitamin D Deficiency Defined as Serum 25OHD < 75 Nmol/l or 30ng/ml; Preeclampsia; Neonatal Hypercalcemia; Pregnancy

 

Last Updated: 25 Jun 2014

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