Arthritis

Common Name(s)

Arthritis

Arthritis is the inflammation of a joint (the point where two bones fit together). There are many types of arthritis and each one has its own cause and symptoms. Typically, all forms of arthritis are associated with symptoms that include pain, stiffness, swelling, redness, and decreased range of motion in the joint that usually gets worse with age. Severe arthritis that affects the hands and arms may make it difficult to do daily tasks while arthritis that affects the knees or ankles may make it difficult to walk or stand. The most common types of arthritis are osteoarthritis and rheumatoid arthritis (RA). Osteoarthritis is caused by the breakdown of the hard tissue that covers and protects the ends of bones (cartilage). Rheumatoid arthritis (RA) is an autoimmune disease that causes the body’s immune system to attack the lining of joints (synovium).

Risk factors for arthritis include a family history of arthritis, increasing age, previous joint injury, obesity and gender, as women are more likely than men to develop RA. Causes of other forms of arthritis include a build up of uric acid crystals in the joint, infections, or underlying disease, such as psoriasis or lupus. Your doctor may use a physical exam, imaging, lab tests and video assessment of your joints to diagnosis arthritis. Imaging can include an X-ray and an MRI to get a detailed look at the joint and cartilage. Doctors may also perform arthroscopy, which uses a small video camera inserted into a small cut near the affected joint to obtain images of the affected area. Although there is no cure for arthritis, there are treatments that help reduce symptoms. These include pain medications, therapy and surgery. If you or someone in your family has been diagnosed with arthritis, talk with a doctor to determine the best treatment plan.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Arthritis" for support, advocacy or research.

International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

Last Updated: 18 Apr 2010

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US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

Last Updated: 24 Sep 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Arthritis" for support, advocacy or research.

International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

http://www.sclero.org/

Last Updated: 18 Apr 2010

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US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

http://www.uspainfoundation.org

Last Updated: 24 Sep 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Arthritis" returned 14061 free, full-text research articles on human participants. First 3 results:

Effect of Tumor Necrosis Factor Inhibitor Therapy on Osteoclasts Precursors in Rheumatoid Arthritis.
 

Author(s): Inês P Perpétuo, Joana Caetano-Lopes, Ana Maria Rodrigues, Raquel Campanilho-Marques, Cristina Ponte, Helena Canhão, Mari Ainola, João E Fonseca

Journal: Biomed Res Int. 2017 ;2017():2690402.

 

Objective. Tumor necrosis factor (TNF) increases circulating osteoclast (OC) precursors numbers by promoting their proliferation and differentiation. The aim of this study was to assess the effect of TNF inhibitors (TNFi) on the differentiation and activity of OC in rheumatoid arthritis ...

Last Updated: 13 Mar 2017

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Vital Signs: Prevalence of Doctor-Diagnosed Arthritis and Arthritis-Attributable Activity Limitation - United States, 2013-2015.
 

Author(s): Kamil E Barbour, Charles G Helmick, Michael Boring, Teresa J Brady

Journal:

 

In the United States, doctor-diagnosed arthritis is a common and disabling chronic condition. Arthritis can lead to severe joint pain and poor physical function, and it can negatively affect quality of life.

Last Updated: 9 Mar 2017

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Results of Total Elbow Arthroplasty with Cementless Implantation of an Alumina Ceramic Elbow Prosthesis for Patients with Rheumatoid Arthritis.
 

Author(s): Keiichiro Nishida, Kenzo Hashizume, Masatsugu Ozawa, Ayumu Takeshita, Daisuke Kaneda, Ryuichi Nakahara, Yoshihisa Nasu, Yasunori Shimamura, Hajime Inoue, Toshifumi Ozaki

Journal: Acta Med. Okayama. 2017 Feb;71(1):41-47.

 

We investigated the long-term clinical results of total elbow arthroplasty (TEA) by cementless fixation of alumina ceramic unlinked elbow prostheses (J-alumina ceramic elbows: JACE) for the reconstruction of elbow joints with rheumatoid arthritis (RA). Seventeen elbows in 17 patients ...

Last Updated: 26 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Arthritis" returned 1690 free, full-text review articles on human participants. First 3 results:

The Mechanisms Underlying Chronic Inflammation in Rheumatoid Arthritis from the Perspective of the Epigenetic Landscape.
 

Author(s): Yasuto Araki, Toshihide Mimura

Journal: J Immunol Res. 2016 ;2016():6290682.

 

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that is characterized by synovial hyperplasia and progressive joint destruction. The activation of RA synovial fibroblasts (SFs), also called fibroblast-like synoviocytes (FLS), contributes significantly to perpetuation ...

Last Updated: 24 Jan 2017

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A better understanding of juvenile idiopathic arthritis with classification criteria.
 

Author(s): Shinji Akioka

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2016 ;39(6):513-521.

 

  Juvenile idiopathic arthritis, JIA, is a novel rheumatic disease in childhood introduced by the International League of Associations for Rheumatology. It is defined as a chronic, inflammatory disorder of unknown etiology, which is classified into seven categories; systemic-onset ...

Last Updated: 4 Jan 2017

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Treatment strategy of elderly rheumatoid arthritis.
 

Author(s): Tsuyoshi Takeda

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2016 ;39(6):497-504.

 

  Since the general population is ageing, the number and the mean age of elderly patients of rheumatoid arthritis (RA) have increased. Elderly RA is classified into two clinical subsets, younger onset elderly RA (YORA) and elderly-onset RA (EORA). In the past literature, onset after ...

Last Updated: 4 Jan 2017

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

CPMC Early Undifferentiated Arthritis Registry
 

Status: Recruiting

Condition Summary: Arthritis

 

Last Updated: 31 Jan 2017

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Discovering the Antecedents of Rheumatoid Arthritis Flare
 

Status: Recruiting

Condition Summary: Rheumatoid Arthritis

 

Last Updated: 6 Oct 2016

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Pro-calcitonin for Early Detection of Septic Arthritis
 

Status: Recruiting

Condition Summary: Arthritis, Infectious

 

Last Updated: 17 Nov 2015

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