Arthritis

Common Name(s)

Arthritis

Arthritis is the inflammation of a joint (the point where two bones fit together). There are many types of arthritis and each one has its own cause and symptoms. Typically, all forms of arthritis are associated with symptoms that include pain, stiffness, swelling, redness, and decreased range of motion in the joint that usually gets worse with age. Severe arthritis that affects the hands and arms may make it difficult to do daily tasks while arthritis that affects the knees or ankles may make it difficult to walk or stand. The most common types of arthritis are osteoarthritis and rheumatoid arthritis (RA). Osteoarthritis is caused by the breakdown of the hard tissue that covers and protects the ends of bones (cartilage). Rheumatoid arthritis (RA) is an autoimmune disease that causes the body’s immune system to attack the lining of joints (synovium).

Risk factors for arthritis include a family history of arthritis, increasing age, previous joint injury, obesity and gender, as women are more likely than men to develop RA. Causes of other forms of arthritis include a build up of uric acid crystals in the joint, infections, or underlying disease, such as psoriasis or lupus. Your doctor may use a physical exam, imaging, lab tests and video assessment of your joints to diagnosis arthritis. Imaging can include an X-ray and an MRI to get a detailed look at the joint and cartilage. Doctors may also perform arthroscopy, which uses a small video camera inserted into a small cut near the affected joint to obtain images of the affected area. Although there is no cure for arthritis, there are treatments that help reduce symptoms. These include pain medications, therapy and surgery. If you or someone in your family has been diagnosed with arthritis, talk with a doctor to determine the best treatment plan.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Arthritis" for support, advocacy or research.

International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

Last Updated: 18 Apr 2010

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US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

Last Updated: 24 Sep 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Arthritis" for support, advocacy or research.

International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

http://www.sclero.org/

Last Updated: 18 Apr 2010

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US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

http://www.uspainfoundation.org

Last Updated: 24 Sep 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Arthritis" returned 15247 free, full-text research articles on human participants. First 3 results:

Male patients with rheumatoid arthritis have an increased risk of osteoporosis: Frequency and risk factors.
 

Author(s): Seong-Min Kweon, Dong Hyun Sohn, Ji-Heh Park, Jung Hee Koh, Eun-Kyoung Park, Han-Na Lee, Keunyoung Kim, Yunkyung Kim, Geun-Tae Kim, Seung-Geun Lee

Journal: Medicine (Baltimore). 2018 Jun;97(24):e11122.

 

Most previous research investigating osteoporosis in rheumatoid arthritis (RA) has focused on female patients and there is a lack of data regarding clinical characteristics of osteoporosis in male patients with RA.The aim of this study was to compare the frequency of osteoporosis ...

Last Updated: 31 Dec 1969

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Inhibition of NF-κB signaling pathway induces apoptosis and suppresses proliferation and angiogenesis of human fibroblast-like synovial cells in rheumatoid arthritis.
 

Author(s): Zhong-Bin Xia, Fan-Ru Meng, Yu-Xuan Fang, Xia Wu, Chun-Wang Zhang, Ying Liu, Dan Liu, Guo-Qing Li, Fan-Bo Feng, Hai-Yang Qiu

Journal: Medicine (Baltimore). 2018 Jun;97(23):e10920.

 

Rheumatoid arthritis (RA) is the most common inflammatory arthritis and is a major cause of disability. The nuclear factor-kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway has been reported to be involved in the pathogenesis of RA with unclear mechanisms. ...

Last Updated: 31 Dec 1969

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Identification of key genes in rheumatoid arthritis and osteoarthritis based on bioinformatics analysis.
 

Author(s): Naiqiang Zhu, Jingyi Hou, Yuanhao Wu, Geng Li, Jinxin Liu, GuiYun Ma, Bin Chen, Youxin Song

Journal: Medicine (Baltimore). 2018 Jun;97(22):e10997.

 

Rheumatoid arthritis (RA) and osteoarthritis (OA) comprise the most common forms of arthritis. The aim of this study was to identify differentially expressed genes (DEGs) and associated biological processes between RA and OA using a bioinformatics approach to elucidate their potential ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Arthritis" returned 1848 free, full-text review articles on human participants. First 3 results:

One year in review 2018: pathogenesis of rheumatoid arthritis.
 

Author(s): Emanuele Calabresi, Fiorella Petrelli, Angelo Francesco Bonifacio, Ilaria Puxeddu, Alessia Alunno

Journal: Clin. Exp. Rheumatol.. ;36(2):175-184.

 

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that primarily affects joints. The several mechanisms involved in the development of the disease are not completely understood. It has been proposed that different environmental factors, such as cigarette smoking, ...

Last Updated: 31 Dec 1969

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Treatment of chikungunya chronic arthritis: A systematic review.
 

Author(s): Gabriella Maria Pitt Gameiro Sales, Izabel Crystine Pereira Barbosa, Laura Maia Sampaio Canejo Neta, Paloma Lopes de Melo, Raphael de Azevedo Leitão, Hugo Moura de Albuquerque Melo

Journal: Rev Assoc Med Bras (1992). 2018 Jan;64(1):63-70.

 

Chikungunya (CHIK) is a tropical arbovirus, transmitted by the female mosquito Aedes aegypti and Aedes albopictus. In Brazil, there have been cases reported since 2014. The initial manifestations of this virus are sudden onset high fever, headache, chills, rashes, myalgia and intense ...

Last Updated: 31 Dec 1969

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Whether innate immune together with genetic factor are involved in leukemic arthritis?: A case report and review of the literature.
 

Author(s): Danyi Xu, Guanhua Xu, Jin Lin

Journal: Medicine (Baltimore). 2018 Feb;97(7):e9919.

 

We report a case of leukemic arthritis (LA) of monocytic differentiation, which presented with spondyloarthritis-like symptoms and a positive human leukocyte antigen-B27, and discuss its potential mechanisms.The patient was admitted because of pain in her right knee and lower back ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

CPMC Early Undifferentiated Arthritis Registry
 

Status: Recruiting

Condition Summary: Arthritis

 

Last Updated: 23 Jan 2018

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INCMNSZ - Rheumatoid Arthritis Cohort
 

Status: Recruiting

Condition Summary: Early Rheumatoid Arthritis; Rheumatoid Arthritis

 

Last Updated: 9 Jan 2018

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A Nutrition Intervention for Arthritis -3 (WCCR-ARTH3)
 

Status: Recruiting

Condition Summary: Rheumatoid Arthritis

 

Last Updated: 6 Apr 2018

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