Arthritis

Common Name(s)

Arthritis

Arthritis is the inflammation of a joint (the point where two bones fit together). There are many types of arthritis and each one has its own cause and symptoms. Typically, all forms of arthritis are associated with symptoms that include pain, stiffness, swelling, redness, and decreased range of motion in the joint that usually gets worse with age. Severe arthritis that affects the hands and arms may make it difficult to do daily tasks while arthritis that affects the knees or ankles may make it difficult to walk or stand. The most common types of arthritis are osteoarthritis and rheumatoid arthritis (RA). Osteoarthritis is caused by the breakdown of the hard tissue that covers and protects the ends of bones (cartilage). Rheumatoid arthritis (RA) is an autoimmune disease that causes the body’s immune system to attack the lining of joints (synovium).

Risk factors for arthritis include a family history of arthritis, increasing age, previous joint injury, obesity and gender, as women are more likely than men to develop RA. Causes of other forms of arthritis include a build up of uric acid crystals in the joint, infections, or underlying disease, such as psoriasis or lupus. Your doctor may use a physical exam, imaging, lab tests and video assessment of your joints to diagnosis arthritis. Imaging can include an X-ray and an MRI to get a detailed look at the joint and cartilage. Doctors may also perform arthroscopy, which uses a small video camera inserted into a small cut near the affected joint to obtain images of the affected area. Although there is no cure for arthritis, there are treatments that help reduce symptoms. These include pain medications, therapy and surgery. If you or someone in your family has been diagnosed with arthritis, talk with a doctor to determine the best treatment plan.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Arthritis" for support, advocacy or research.

International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

Last Updated: 18 Apr 2010

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US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

Last Updated: 24 Sep 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Arthritis" for support, advocacy or research.

International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

http://www.sclero.org/

Last Updated: 18 Apr 2010

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US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

http://www.uspainfoundation.org

Last Updated: 24 Sep 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Arthritis" returned 12831 free, full-text research articles on human participants. First 3 results:

Autoimmune hepatitis triggered by adalimumab and allergic reactions after various anti-TNFα therapy agents in a patient with rheumatoid arthritis.
 

Author(s): Jana Petríková, Peter Jarčuška, Marián Svajdler, Daniel Pella, Zelmíra Macejová

Journal: Isr. Med. Assoc. J.. 2015 Apr;17(4):256-8.

 

Last Updated: 4 Jun 2015

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Preoperative antibiotics for septic arthritis in children: delay in diagnosis.
 

Author(s): Simon B M MacLean, Christopher Timmis, Scott Evans, Dominik Lawniczak, Amit Nijran, Edward Bache

Journal: J Orthop Surg (Hong Kong). 2015 Apr;23(1):80-3.

 

To review the records of 50 children who underwent open joint washout for septic arthritis with (n=25) or without (n=25) preoperative antibiotics.

Last Updated: 29 Apr 2015

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Disease activity guided dose reduction and withdrawal of adalimumab or etanercept compared with usual care in rheumatoid arthritis: open label, randomised controlled, non-inferiority trial.
 

Author(s): Noortje van Herwaarden, Aatke van der Maas, Michiel J M Minten, Frank H J van den Hoogen, Wietske Kievit, Ronald F van Vollenhoven, Johannes W J Bijlsma, Bart J F van den Bemt, Alfons A den Broeder

Journal:

 

To evaluate whether a disease activity guided strategy of dose reduction of two tumour necrosis factor (TNF) inhibitors, adalimumab or etanercept, is non-inferior in maintaining disease control in patients with rheumatoid arthritis compared with usual care.

Last Updated: 10 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Arthritis" returned 1536 free, full-text review articles on human participants. First 3 results:

Methotrexate use and risk of lung disease in psoriasis, psoriatic arthritis, and inflammatory bowel disease: systematic literature review and meta-analysis of randomised controlled trials.
 

Author(s): Richard Conway, Candice Low, Robert J Coughlan, Martin J O'Donnell, John J Carey

Journal:

 

To evaluate the relative risk of pulmonary disease among patients with psoriasis, psoriatic arthritis, and inflammatory bowel disease treated with methotrexate.

Last Updated: 15 Mar 2015

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The supplementary therapeutic DMARD role of low-dose glucocorticoids in rheumatoid arthritis.
 

Author(s): Maurizio Cutolo, Cornelia M Spies, Frank Buttgereit, Sabrina Paolino, Carmen Pizzorni

Journal:

 

The management of rheumatoid arthritis (RA) is primarily based on the use of disease-modifying antirheumatic drugs (DMARDs), mainly comprising synthetic chemical compounds (that is, methotrexate or leflunomide) and biological agents (tumor necrosis factor inhibitors or abatacept). ...

Last Updated: 22 Jan 2015

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The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis, psoriasis and psoriatic arthritis: a systematic review and meta-analysis.
 

Author(s): Camille Roubille, Vincent Richer, Tara Starnino, Collette McCourt, Alexandra McFarlane, Patrick Fleming, Stephanie Siu, John Kraft, Charles Lynde, Janet Pope, Wayne Gulliver, Stephanie Keeling, Jan Dutz, Louis Bessette, Robert Bissonnette, Boulos Haraoui

Journal: Ann. Rheum. Dis.. 2015 Mar;74(3):480-9.

 

The objective of this systematic literature review was to determine the association between cardiovascular events (CVEs) and antirheumatic drugs in rheumatoid arthritis (RA) and psoriatic arthritis (PsA)/psoriasis (Pso). Systematic searches were performed of MEDLINE, EMBASE and Cochrane ...

Last Updated: 6 Feb 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

An MRI-guided Treatment Strategy to Prevent Disease Progression in Patients With Rheumatoid Arthritis
 

Status: Recruiting

Condition Summary: Arthritis; Arthritis, Rheumatoid; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Autoimmune Diseases

 

Last Updated: 16 Feb 2015

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Yoga as Self-Care for Arthritis in Minority Communities
 

Status: Recruiting

Condition Summary: Rheumatoid Arthritis; Arthritis

 

Last Updated: 30 Oct 2014

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