Precocious puberty

Common Name(s)

Precocious puberty

Precocious puberty is when a child goes through puberty too soon. Puberty is the physical changes a child goes through when their body is maturing into an adult body capable of reproduction. Precocious puberty is defined as a girl beginning puberty before age 8, and a boy reaching puberty before age 9. Symptoms in girls include breast growth and menstruation, while symptoms in boys include facial hair, deepening voice, and enlarged testicles. Both boys and girls will experience rapid growth, pubic and underarm hair, and acne. The causes of precocious puberty are not entirely known in most cases. In rare cases, tumors, infections, hormone disorders, or brain abnormalities may be the cause of precocious puberty. Treatment may include medications that help delay puberty.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Precocious puberty" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Precocious puberty" returned 195 free, full-text research articles on human participants. First 3 results:

The Influence of GnRH Analog Therapy on Growth in Central Precocious Puberty.
 

Author(s): Ewa Głąb, Beata Wikiera, Jolanta Bieniasz, Ewa Barg

Journal: Adv Clin Exp Med. ;25(1):27-32.

 

Children with central precocious puberty (CPP) present various somatic and psychological abnormalities.

Last Updated: 3 Mar 2016

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A Significant Increase in the Incidence of Central Precocious Puberty among Korean Girls from 2004 to 2010.
 

Author(s): Shin Hye Kim, Kyoung Huh, Sungho Won, Kuk-Wha Lee, Mi-Jung Park

Journal:

 

Few studies have explored the trends in central precocious puberty (CPP) in Asian populations. This study assessed the prevalence and annual incidence of CPP among Korean children.

Last Updated: 6 Nov 2015

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A case of familial central precocious puberty caused by a novel mutation in the makorin RING finger protein 3 gene.
 

Author(s): Anna Grandone, Grazia Cantelmi, Grazia Cirillo, Pierluigi Marzuillo, Caterina Luongo, Emanuele Miraglia del Giudice, Laura Perrone

Journal:

 

Central precocious puberty (CPP) is often familial but its genetic cause is largely unknown. Very recently, the makorin RING finger protein 3 (MKRN3) gene, located on chromosome 15 in the Prader-Willi syndrome (PWS)-associated region (15q11-q13), has been found mutated in 5 families ...

Last Updated: 27 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Precocious puberty" returned 18 free, full-text review articles on human participants. First 3 results:

Optic glioma and precocious puberty in a girl with neurofibromatosis type 1 carrying an R681X mutation of NF1: case report and review of the literature.
 

Author(s): Mirjana Kocova, Elena Kochova, Elena Sukarova-Angelovska

Journal:

 

Neurofibromatosis type 1 (NF1) is a common autosomal dominant genetic disorder with an extremely variable phenotype. In childhood NF1 can be associated with optic glioma and central precocious puberty; the latter is more common when the optic chiasm is affected. The mutational spectrum ...

Last Updated: 15 Dec 2015

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Association of PAEs with Precocious Puberty in Children: A Systematic Review and Meta-Analysis.
 

Author(s): Yi Wen, Shu-Dan Liu, Xun Lei, Yu-Shuang Ling, Yan Luo, Qin Liu

Journal:

 

Precocious puberty (PP) currently affects 1 in 5000 children and is 10 times more common in girls. Existing studies have tried to detect an association between phathalic acid esters (PAEs) and PP, but the results did not reach a consensus.

Last Updated: 4 Dec 2015

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MANAGEMENT OF ENDOCRINE DISEASE: Long-term outcomes of the treatment of central precocious puberty.
 

Author(s): Federica Guaraldi, Guglielmo Beccuti, Davide Gori, Lucia Ghizzoni

Journal: Eur. J. Endocrinol.. 2016 Mar;174(3):R79-87.

 

GnRH analogues (GnRHa) are the treatment of choice for central precocious puberty (CPP), with the main objective to recover the height potential compromised by the premature fusion of growth cartilages. The aim of this review was to analyze long-term effects of GnRHa on height, body ...

Last Updated: 16 Jan 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Follow-up of Girls With Premature Thelarche and Precocious Puberty
 

Status: Not yet recruiting

Condition Summary: Precocious Puberty; Excess; Development, Breast

 

Last Updated: 12 Sep 2013

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First-Voided Urinary LH vs. GnRH-stimulation in Differentiating Slowly- From Rapidly Progressive-Precocious Puberty
 

Status: Recruiting

Condition Summary: Precocious Puberty, Gonadotropin-dependent

 

Last Updated: 25 Feb 2013

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Markers of Pubertal Suppression During Therapy for Precocious Puberty
 

Status: Recruiting

Condition Summary: Central Precocious Puberty

 

Last Updated: 3 Sep 2014

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