Precocious puberty

Common Name(s)

Precocious puberty

Precocious puberty is when a child goes through puberty too soon. Puberty is the physical changes a child goes through when their body is maturing into an adult body capable of reproduction. Precocious puberty is defined as a girl beginning puberty before age 8, and a boy reaching puberty before age 9. Symptoms in girls include breast growth and menstruation, while symptoms in boys include facial hair, deepening voice, and enlarged testicles. Both boys and girls will experience rapid growth, pubic and underarm hair, and acne. The causes of precocious puberty are not entirely known in most cases. In rare cases, tumors, infections, hormone disorders, or brain abnormalities may be the cause of precocious puberty. Treatment may include medications that help delay puberty.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Precocious puberty" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Precocious puberty" returned 159 free, full-text research articles on human participants. First 3 results:

Long-Term Continuous Suppression With Once-Yearly Histrelin Subcutaneous Implants for the Treatment of Central Precocious Puberty: A Final Report of a Phase 3 Multicenter Trial.
 

Author(s): Lawrence A Silverman, E Kirk Neely, Gad B Kletter, Katherine Lewis, Surya Chitra, Oksana Terleckyj, Erica A Eugster

Journal: J. Clin. Endocrinol. Metab.. 2015 Jun;100(6):2354-63.

 

The histrelin implant has proven to be an effective method of delivering GnRH analog (GnRHa) therapy to children with central precocious puberty (CPP), yet there are limited data available regarding hormonal suppression and auxological changes during an extended course of therapy.

Last Updated: 6 Jun 2015

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[Advances in the etiology, diagnosis and treatment of central precocious puberty].
 

Author(s): Delanie B Macedo, Priscilla Cukier, Berenice B Mendonca, Ana Claudia Latronico, Vinicius Nahime Brito

Journal: Arq Bras Endocrinol Metabol. 2014 Mar;58(2):108-17.

 

The onset of puberty is first detected as an increase in the amplitude and frequency of pulses of gonadotropin-releasing hormone (GnRH) after a quiescent period during childhood. The reemergence of pulsatile GnRH secretion leads to increases in the secretion of the gonadotropins, ...

Last Updated: 16 May 2014

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Central precocious puberty in a 3 year-old girl with Phenylketonuria: a rare association?
 

Author(s): Laura Lucaccioni, Bernd C Schwahn, Malcolm Donaldson, Claudio Giacomozzi

Journal:

 

Central precocious puberty (CPP) and phenylketonuria (PKU) are two rare conditions, the latter being the rarer. To date, only one case featuring both these conditions has been reported, and hyperphenylalaninemia was assumed triggering CPP.

Last Updated: 3 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Precocious puberty" returned 13 free, full-text review articles on human participants. First 3 results:

New causes of central precocious puberty: the role of genetic factors.
 

Author(s): Delanie Bulcao Macedo, Vinicius Nahime Brito, Ana Claudia Latronico

Journal: Neuroendocrinology. 2014 ;100(1):1-8.

 

A pivotal event in the onset of puberty in humans is the reemergence of the pulsatile release of the gonadotropin-releasing hormone (GnRH) from hypothalamic neurons. Pathways governing GnRH ontogeny and physiology have been discovered by studying animal models and humans with reproductive ...

Last Updated: 18 Nov 2014

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[Effects of central precocious puberty on physical and sexual development in children].
 

Author(s): Lan Zhao, Yan Zhong

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2014 May;16(5):555-9.

 

As abnormal pubertal development, central precocious puberty (CPP) is manifested by the secondary sexual characteristics, skeletal maturation, and physical development in advance. It ultimately affects the adult height of children, even producing some psychological and behavioral ...

Last Updated: 26 May 2014

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Precocious puberty in Turner Syndrome: report of a case and review of the literature.
 

Author(s): Nicola Improda, Martina Rezzuto, Sara Alfano, Giancarlo Parenti, Pietro Vajro, Claudio Pignata, Mariacarolina Salerno

Journal:

 

Turner Syndrome (TS) is caused by monosomy or structural abnormalities of the X chromosome, with a prevalence of about 1/2000 females live birth. Most important clinical features of TS are short stature and gonadal failure. Approximately one third of girls with TS may undergo spontaneous ...

Last Updated: 29 Oct 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Follow-up of Girls With Premature Thelarche and Precocious Puberty
 

Status: Not yet recruiting

Condition Summary: Precocious Puberty; Excess; Development, Breast

 

Last Updated: 12 Sep 2013

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First-Voided Urinary LH vs. GnRH-stimulation in Differentiating Slowly- From Rapidly Progressive-Precocious Puberty
 

Status: Recruiting

Condition Summary: Precocious Puberty, Gonadotropin-dependent

 

Last Updated: 25 Feb 2013

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Markers of Pubertal Suppression During Therapy for Precocious Puberty
 

Status: Recruiting

Condition Summary: Central Precocious Puberty

 

Last Updated: 3 Sep 2014

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