Precocious puberty

Common Name(s)

Precocious puberty

Precocious puberty is when a child goes through puberty too soon. Puberty is the physical changes a child goes through when their body is maturing into an adult body capable of reproduction. Precocious puberty is defined as a girl beginning puberty before age 8, and a boy reaching puberty before age 9. Symptoms in girls include breast growth and menstruation, while symptoms in boys include facial hair, deepening voice, and enlarged testicles. Both boys and girls will experience rapid growth, pubic and underarm hair, and acne. The causes of precocious puberty are not entirely known in most cases. In rare cases, tumors, infections, hormone disorders, or brain abnormalities may be the cause of precocious puberty. Treatment may include medications that help delay puberty.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Precocious puberty" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Precocious puberty" returned 190 free, full-text research articles on human participants. First 3 results:

A Significant Increase in the Incidence of Central Precocious Puberty among Korean Girls from 2004 to 2010.
 

Author(s): Shin Hye Kim, Kyoung Huh, Sungho Won, Kuk-Wha Lee, Mi-Jung Park

Journal:

 

Few studies have explored the trends in central precocious puberty (CPP) in Asian populations. This study assessed the prevalence and annual incidence of CPP among Korean children.

Last Updated: 6 Nov 2015

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[Effects of HPGA suppression on predicted adult height in girls with central precocious puberty].
 

Author(s): Yue-Hong Tao, Bi-He Zeng, Nazir Sharif

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2015 Oct;17(10):1093-7.

 

To study the relationship between the suppression of the hypothalamic-pituitary-gonadal axis (HPGA) and the predicted adult height (PAH) in girls with central precocious puberty (CPP) during the treatment with gonadotropin-releasing hormone analogue (GnRHa), in order to provide guidance ...

Last Updated: 20 Oct 2015

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[Effects of obesity on peak level of luteinizing hormone in gonadotropin-releasing hormone agonist test and obesity-related hormones in girls with central precocious puberty].
 

Author(s): Xue-Lian Zhou, Jun-Fen Fu, Ju-Hua Jin, Guan-Ping Dong, You-Jun Jiang, Ke Huang, Xue-Feng Chen, Wei Wu

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2015 Aug;17(8):763-8.

 

To explore the effects of obesity on the peak level of luteinizing hormone (LH) in the gonadotropin-releasing hormone (GnRH) agonist test and obesity-related hormones in girls with central precocious puberty (CPP).

Last Updated: 20 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Precocious puberty" returned 16 free, full-text review articles on human participants. First 3 results:

MANAGEMENT OF ENDOCRINE DISEASE: Long-term outcomes of the treatment of central precocious puberty.
 

Author(s): Federica Guaraldi, Guglielmo Beccuti, Davide Gori, Lucia Ghizzoni

Journal: Eur. J. Endocrinol.. 2016 Mar;174(3):R79-87.

 

GnRH analogues (GnRHa) are the treatment of choice for central precocious puberty (CPP), with the main objective to recover the height potential compromised by the premature fusion of growth cartilages. The aim of this review was to analyze long-term effects of GnRHa on height, body ...

Last Updated: 16 Jan 2016

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Gonadotropin releasing hormone agonist treatment to increase final stature in children with precocious puberty: a meta-analysis.
 

Author(s): Pin Li, Yan Li, Chung-Lin Yang

Journal: Medicine (Baltimore). 2014 Dec;93(27):e260.

 

In the setting of central precocious puberty (CPP), the motivation for hormonal intervention is to help the child to reach a taller adult stature than she would achieve otherwise. While gonadotropin-releasing hormone analogs (GnRHa) constitute an established treatment for improving ...

Last Updated: 16 Dec 2014

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New causes of central precocious puberty: the role of genetic factors.
 

Author(s): Delanie Bulcao Macedo, Vinicius Nahime Brito, Ana Claudia Latronico

Journal: Neuroendocrinology. 2014 ;100(1):1-8.

 

A pivotal event in the onset of puberty in humans is the reemergence of the pulsatile release of the gonadotropin-releasing hormone (GnRH) from hypothalamic neurons. Pathways governing GnRH ontogeny and physiology have been discovered by studying animal models and humans with reproductive ...

Last Updated: 18 Nov 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Follow-up of Girls With Premature Thelarche and Precocious Puberty
 

Status: Not yet recruiting

Condition Summary: Precocious Puberty; Excess; Development, Breast

 

Last Updated: 12 Sep 2013

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First-Voided Urinary LH vs. GnRH-stimulation in Differentiating Slowly- From Rapidly Progressive-Precocious Puberty
 

Status: Recruiting

Condition Summary: Precocious Puberty, Gonadotropin-dependent

 

Last Updated: 25 Feb 2013

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Markers of Pubertal Suppression During Therapy for Precocious Puberty
 

Status: Recruiting

Condition Summary: Central Precocious Puberty

 

Last Updated: 3 Sep 2014

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