Precocious puberty

Common Name(s)

Precocious puberty

Precocious puberty is when a child goes through puberty too soon. Puberty is the physical changes a child goes through when their body is maturing into an adult body capable of reproduction. Precocious puberty is defined as a girl beginning puberty before age 8, and a boy reaching puberty before age 9. Symptoms in girls include breast growth and menstruation, while symptoms in boys include facial hair, deepening voice, and enlarged testicles. Both boys and girls will experience rapid growth, pubic and underarm hair, and acne. The causes of precocious puberty are not entirely known in most cases. In rare cases, tumors, infections, hormone disorders, or brain abnormalities may be the cause of precocious puberty. Treatment may include medications that help delay puberty.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Precocious puberty" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Precocious puberty" returned 194 free, full-text research articles on human participants. First 3 results:

Serum Anti-Müllerian Hormone Levels in Precocious Puberty Girls according to Stage of GnRH Agonist Treatment.
 

Author(s): Hyo Kyoung Nam, Hye Ryun Kim, Young Jun Rhie, Kee Hyoung Lee

Journal: J. Korean Med. Sci.. 2017 Mar;32(3):475-479.

 

Few studies have investigated the long-term effects of gonadotropin-releasing hormone (GnRH) agonist treatment on the reproductive function of central precocious puberty (CPP) girls. In this cross-sectional study, we assessed the ovarian function by analyzing the serum anti-Müllerian ...

Last Updated: 1 Feb 2017

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Predictive Value of Dental Maturity for a Positive Gonadotropin-Releasing Hormone Stimulation Test Result in Girls with Precocious Puberty.
 

Author(s): Jee Seon Baik, Jin Woo Choi, Su Jin Kim, Ji Hyun Kim, Sollip Kim, Jae Hyun Kim

Journal: J. Korean Med. Sci.. 2017 Feb;32(2):296-302.

 

Dental maturity is associated with skeletal maturity, which is advanced in girls with central precocious puberty (CPP). We investigated the performance of dental maturity as a screening method for CPP using mandibular second premolar and molar calcification stages, assessed the associated ...

Last Updated: 3 Jan 2017

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A 6-Month Trial of the Efficacy and Safety of Triptorelin Pamoate (11.25 mg) Every 3 Months in Children with Precocious Puberty: A Retrospective Comparison with Triptorelin Acetate.
 

Author(s): Delphine Zenaty, Joelle Blumberg, Nilani Liyanage, Evelyne Jacqz-Aigrain, Najiba Lahlou, Jean-Claude Carel,

Journal: Horm Res Paediatr. 2016 ;86(3):188-195.

 

To evaluate the efficacy and safety of a triptorelin pamoate (11.25 mg) 3-month formulation in the management of central precocious puberty (CPP) (TP Study) and to retrospectively compare it with a triptorelin acetate (11.25 mg) 3-month formulation (TA Study).

Last Updated: 12 Sep 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Precocious puberty" returned 17 free, full-text review articles on human participants. First 3 results:

Treatment of Peripheral Precocious Puberty.
 

Author(s): Melissa Schoelwer, Erica A Eugster

Journal: Endocr Dev. 2016 ;29():230-9.

 

There are many etiologies of peripheral precocious puberty (PPP) with diverse manifestations resulting from exposure to androgens, estrogens, or both. The clinical presentation depends on the underlying process and may be acute or gradual. The primary goals of therapy are to halt ...

Last Updated: 18 Dec 2015

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Optic glioma and precocious puberty in a girl with neurofibromatosis type 1 carrying an R681X mutation of NF1: case report and review of the literature.
 

Author(s): Mirjana Kocova, Elena Kochova, Elena Sukarova-Angelovska

Journal:

 

Neurofibromatosis type 1 (NF1) is a common autosomal dominant genetic disorder with an extremely variable phenotype. In childhood NF1 can be associated with optic glioma and central precocious puberty; the latter is more common when the optic chiasm is affected. The mutational spectrum ...

Last Updated: 15 Dec 2015

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Association of PAEs with Precocious Puberty in Children: A Systematic Review and Meta-Analysis.
 

Author(s): Yi Wen, Shu-Dan Liu, Xun Lei, Yu-Shuang Ling, Yan Luo, Qin Liu

Journal:

 

Precocious puberty (PP) currently affects 1 in 5000 children and is 10 times more common in girls. Existing studies have tried to detect an association between phathalic acid esters (PAEs) and PP, but the results did not reach a consensus.

Last Updated: 4 Dec 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Clinical Trial of Experienced Chinese Herbal Formulas on Different Types of Precocious Puberty
 

Status: Recruiting

Condition Summary: Precocious Puberty

 

Last Updated: 30 Apr 2016

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Analysis of Body Mass Index in Central Precocious Puberty Patients Treated With Leuprolide Acetate
 

Status: Recruiting

Condition Summary: Precocious Puberty, Central

 

Last Updated: 22 Nov 2016

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Last Updated: 24 Mar 2017

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