Post Polio syndrome

Common Name(s)

Post Polio syndrome

Post polio syndrome (PPS) is a condition that affects polio survivors years after recovery from the initial polio illness. Symptoms and severity vary among affected people and may include muscle weakness and a gradual decrease in the size of muscles (atrophy); muscle and joint pain; fatigue; difficulty with gait; respiratory problems; and/or swallowing problems.  Only a polio survivor can develop PPS. While polio is a contagious disease, PPS is not. The exact cause of PPS years after the first episode of polio is unclear, although several theories have been proposed. Treatment focuses on reducing symptoms and improving quality of life.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Post Polio syndrome" for support, advocacy or research.

United Spinal Association

United Spinal Association’s mission is to improve the quality of life of all people living with spinal cord injuries and disorders (SCI/D). United Spinal never loses sight of our founders' grassroots efforts to provide a voice to the disability community and to transform the public’s perception of wheelchair users. Now the largest non-profit organization dedicated to helping people living with SCI/D, United Spinal is committed to providing active-lifestyle information, peer support and advocacy that empowers individuals to achieve their highest potential in all facets of life.

Last Updated: 20 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Post Polio syndrome" for support, advocacy or research.

United Spinal Association

United Spinal Association’s mission is to improve the quality of life of all people living with spinal cord injuries and disorders (SCI/D). United Spinal never loses sight of our founders' grassroots efforts to provide a voice to the disability community and to transform the public’s perception of wheelchair users. Now the largest non-profit organization dedicated to helping people living with SCI/D, United Spinal is committed to providing active-lifestyle information, peer support and advocacy that empowers individuals to achieve their highest potential in all facets of life.

http://www.unitedspinal.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Post Polio syndrome" returned 30 free, full-text research articles on human participants. First 3 results:

Immunoglobulin treatment in post-polio syndrome: Identification of responders and non-responders.
 

Author(s): Gunilla Östlund, Lisbet Broman, Lars Werhagen, Kristian Borg

Journal: J Rehabil Med. 2015 Sep;47(8):727-33.

 

To define and characterize responders and non-responders in a group of 124 patients with post-polio syndrome who received a single treatment with intravenous immunoglobulin.

Last Updated: 3 Sep 2015

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Elevated blood lipids are uncommon in patients with post-polio syndrome--a cross sectional study.
 

Author(s): Eva Melin, Thomas Kahan, Kristian Borg

Journal:

 

The post-polio syndrome occurs in people who previously have had poliomyelitis. After the initial recovery, new or increasing neurologic symptoms occur. Inflammation and dyslipidaemia may play an important role in the development of atherosclerotic complications, for example myocardial ...

Last Updated: 13 May 2015

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Multidimensional fatigue inventory and post-polio syndrome - a Rasch analysis.
 

Author(s): Anna Dencker, Katharina S Sunnerhagen, Charles Taft, Åsa Lundgren-Nilsson

Journal:

 

Fatigue is a common symptom in post-polio syndrome (PPS) and can have a substantial impact on patients. There is a need for validated questionnaires to assess fatigue in PPS for use in clinical practice and research. The aim with this study was to assess the validity and reliability ...

Last Updated: 17 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Post Polio syndrome" returned 3 free, full-text review articles on human participants. First 3 results:

Post-polio syndrome: Pathophysiological hypotheses, diagnosis criteria, drug therapy.
 

Author(s): F-C Boyer, V Tiffreau, A Rapin, I Laffont, L Percebois-Macadré, C Supper, J-L Novella, A-P Yelnik

Journal: Ann Phys Rehabil Med. 2010 Feb;53(1):34-41.

 

Post-polio syndrome (PPS) refers to a clinical disorder affecting polio survivors with sequelae years after the initial polio attack. These patients report new musculoskeletal symptoms, loss of muscular strength or endurance. PPS patients are tired, in pain and experience new and ...

Last Updated: 15 Feb 2010

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Post-polio syndrome and rehabilitation.
 

Author(s): V Tiffreau, A Rapin, R Serafi, L Percebois-Macadré, C Supper, D Jolly, F-C Boyer

Journal: Ann Phys Rehabil Med. 2010 Feb;53(1):42-50.

 

Post-polio syndrome (PPS) is the commonly affected term to describe the symptoms that may develop many years after acute paralytic poliomyelitis. The etiology of PPS is still unclear. An overuse of enlarged motor units is suspected causing denervation again due to distal degeneration ...

Last Updated: 15 Feb 2010

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[Post-polio syndrome: a review of its clinical characteristics and treatment].
 

Author(s): C Bouza, J M Amate

Journal: Rev Neurol. ;43(5):295-301.

 

Post-polio syndrome (PPS) is recognised as a clinical syndrome that causes the late, progressive functional impairment suffered by survivors of an acute episode of poliomyelitis. The importance of PPS is acknowledged by increasingly wider sectors of the population and health care ...

Last Updated: 30 Aug 2006

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

L-Citrulline in Patients With Post-Polio Syndrome
 

Status: Recruiting

Condition Summary: Post-Polio Syndrome

 

Last Updated: 10 Jun 2016

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Last Updated: 5 Apr 2016

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Comparing Functional Outcomes in Individuals Using Micro-processor Controlled Orthosis Versus Stance Control Orthosis
 

Status: Recruiting

Condition Summary: Spinal Cord Injuries; Poliomyelitis; Post-polio Syndrome; Arthritis; Lower Motor Neurone Lesion

 

Last Updated: 6 May 2016

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