Portal hypertension

Common Name(s)

Portal hypertension

Portal hypertension is abnormally high blood pressure in branches of the portal vein, the large vein that brings blood from the intestine to the liver. Portal hypertension itself does not cause symptoms, but complications from the condition can lead to an enlarged abdomen, abdominal discomfort, confusion, drowsiness and internal bleeding. It may be caused by a variety of conditions, but cirrhosis is the most common cause in Western countries. Treatment is generally directed toward the cause of the condition, although emergency treatment is sometimes needed for serious complications.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Portal hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Portal hypertension" returned 467 free, full-text research articles on human participants. First 3 results:

Clinical outcomes of transjugular intrahepatic portosystemic shunt for portal hypertension: Korean multicenter real-practice data.
 

Author(s): Hyung Ki Kim, Yoon Jun Kim, Woo Jin Chung, Soon Sun Kim, Jae Jun Shim, Moon Seok Choi, Do Young Kim, Dae Won Jun, Soon Ho Um, Sung Jae Park, Hyun Young Woo, Young Kul Jung, Soon Koo Baik, Moon Young Kim, Soo Young Park, Jae Myeong Lee, Young Seok Kim

Journal: Clin Mol Hepatol. 2014 Mar;20(1):18-27.

 

This retrospective study assessed the clinical outcome of a transjugular intrahepatic portosystemic shunt (TIPS) procedure for managing portal hypertension in Koreans with liver cirrhosis.

Last Updated: 23 Apr 2014

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Idiopathic non cirrhotic portal hypertension and spleno-portal axis abnormalities in patients with severe primary antibody deficiencies.
 

Author(s): Federica Pulvirenti, Ilaria Pentassuglio, Cinzia Milito, Michele Valente, Adriano De Santis, Valentina Conti, Giulia d'Amati, Oliviero Riggio, Isabella Quinti

Journal: J Immunol Res. 2014 ;2014():672458.

 

Portal hypertension has been reported in association with acquired and primary immune deficiencies without a comprehensive description of associated spleno-portal axis abnormalities. Pathological mechanisms are poorly defined.

Last Updated: 17 Apr 2014

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Effects of secondary left-sided portal hypertension on the radical operation rate and prognosis in patients with pancreatic cancer.
 

Author(s): Shuo Zhang, Dong-Qing Wen, Ya-Lin Kong, Ya-Li Li, Hong-Yi Zhang

Journal: Asian Pac. J. Cancer Prev.. 2014 ;15(5):2239-44.

 

To investigate the effects of secondary left-sided portal hypertension (LSPH) on the radical operation rate of patients with pancreatic cancer and systemically evaluate the prognosis of patients with LSPH secondary to pancreatic cancer after radical surgery.

Last Updated: 10 Apr 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Portal hypertension" returned 84 free, full-text review articles on human participants. First 3 results:

Non-cirrhotic portal hypertension - diagnosis and management.
 

Author(s): Rajeev Khanna, Shiv K Sarin

Journal: J. Hepatol.. 2014 Feb;60(2):421-41.

 

NCPH is a heterogeneous group of liver disorders of vascular origin, leading to PHT with near normal HVPG. NCPF/IPH is a disorder of young adults or middle aged women, whereas EHPVO is a disorder of childhood. Early age acute or recurrent infections in an individual with thrombotic ...

Last Updated: 20 Jan 2014

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Portal hypertension and gastrointestinal bleeding: diagnosis, prevention and management.
 

Author(s): Erwin Biecker

Journal: World J. Gastroenterol.. 2013 Aug;19(31):5035-50.

 

Bleeding from esophageal varices is a life threatening complication of portal hypertension. Primary prevention of bleeding in patients at risk for a first bleeding episode is therefore a major goal. Medical prophylaxis consists of non-selective beta-blockers like propranolol or carvedilol. ...

Last Updated: 21 Aug 2013

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Current concepts on the role of nitric oxide in portal hypertension.
 

Author(s): Liang Shuo Hu, Jacob George, Jian Hua Wang

Journal: World J. Gastroenterol.. 2013 Mar;19(11):1707-17.

 

Portal hypertension (PHT) is defined as a pathological increase in portal venous pressure and frequently accompanies cirrhosis. Portal pressure can be increased by a rise in portal blood flow, an increase in vascular resistance, or the combination. In cirrhosis, the primary factor ...

Last Updated: 4 Apr 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

MRI in Portal Hypertension
 

Status: Recruiting

Condition Summary: Portal Hypertension

 

Last Updated: 14 Jan 2014

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Value of Von Willebrand Factor in Portal Hypertension
 

Status: Recruiting

Condition Summary: Liver Cirrhosis; Portal Hypertension

 

Last Updated: 23 Oct 2013

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A Study of IDN-6556 in Cirrhotic Subjects With Portal Hypertension
 

Status: Recruiting

Condition Summary: Liver Cirrhosis; Hepatic Cirrhosis; Portal Hypertension

 

Last Updated: 4 Nov 2014

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