Portal hypertension

Common Name(s)

Portal hypertension

Portal hypertension is abnormally high blood pressure in branches of the portal vein, the large vein that brings blood from the intestine to the liver. Portal hypertension itself does not cause symptoms, but complications from the condition can lead to an enlarged abdomen, abdominal discomfort, confusion, drowsiness and internal bleeding. It may be caused by a variety of conditions, but cirrhosis is the most common cause in Western countries. Treatment is generally directed toward the cause of the condition, although emergency treatment is sometimes needed for serious complications.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Portal hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Portal hypertension" returned 482 free, full-text research articles on human participants. First 3 results:

Comparison of effects of devascularization versus shunt on patients with portal hypertension: a meta-analysis.
 

Author(s): G-Q Zong, Y Fei, R-M Liu

Journal: Chirurgia (Bucur). ;110(1):15-25.

 

To systematically evaluate the effectiveness of devascularization and shunt on patients with portal hypertension.

Last Updated: 24 Mar 2015

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Development of nodular regenerative hyperplasia (NRH) with portal hypertension following the administration of oxaliplatin for the recurrence of colon cancer.
 

Author(s): Hiroaki Takaya, Hideto Kawaratani, Keisuke Nakanishi, Shinya Takeyama, Chie Morioka, Masayoshi Sawai, Masahisa Toyohara, Masao Fujimoto, Hitoshi Yoshiji, Junichi Yamao, Hiroshi Fukui

Journal: Intern. Med.. 2015 ;54(4):383-7.

 

Nodular regenerative hyperplasia (NRH) is associated with autoimmune and hematologic diseases and may lead to portal hypertension. We herein report a case of NRH diagnosed based on a liver biopsy. A 63-year-old woman developed esophageal varices and splenomegaly. She had undergone ...

Last Updated: 9 Mar 2015

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Splenic artery ligature associated with endoscopic banding for schistosomal portal hypertension.
 

Author(s): Renata Potonyacz Colaneri, Fabrício Ferreira Coelho, Roberto de Cleva, Marcos Vinícius Perini, Paulo Herman

Journal: World J. Gastroenterol.. 2014 Nov;20(44):16734-8.

 

To propose a less invasive surgical treatment for schistosomal portal hypertension.

Last Updated: 3 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Portal hypertension" returned 109 free, full-text review articles on human participants. First 3 results:

The accuracy of ultrasonography for the evaluation of portal hypertension in patients with cirrhosis: a systematic review.
 

Author(s): Gaeun Kim, Youn Zoo Cho, Soon Koo Baik, Moon Young Kim, Won Ki Hong, Sang Ok Kwon

Journal: Korean J Radiol. ;16(2):314-24.

 

Studies have presented conflicting results regarding the accuracy of ultrasonography (US) for diagnosing portal hypertension (PH). We sought to identify evidence in the literature regarding the accuracy of US for assessing PH in patients with liver cirrhosis.

Last Updated: 5 Mar 2015

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Extrahepatic complications to cirrhosis and portal hypertension: haemodynamic and homeostatic aspects.
 

Author(s): Søren Møller, Jens H Henriksen, Flemming Bendtsen

Journal: World J. Gastroenterol.. 2014 Nov;20(42):15499-517.

 

In addition to complications relating to the liver, patients with cirrhosis and portal hypertension develop extrahepatic functional disturbances of multiple organ systems. This can be considered a multiple organ failure that involves the heart, lungs, kidneys, the immune systems, ...

Last Updated: 17 Nov 2014

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Utility of endoscopic ultrasound in patients with portal hypertension.
 

Author(s): Ghassan M Hammoud, Jamal A Ibdah

Journal: World J. Gastroenterol.. 2014 Oct;20(39):14230-6.

 

Endoscopic ultrasound (EUS) has revolutionized the diagnostic and therapeutic approach to patients with gastrointestinal disorders. Its application in patients with liver disease and portal hypertension is increasing. Patients with chronic liver disease are at risk for development ...

Last Updated: 23 Oct 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

MRI in Portal Hypertension
 

Status: Recruiting

Condition Summary: Portal Hypertension

 

Last Updated: 14 Jan 2014

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Transient Elastography to Assess Liver Fibrosis and Portal Hypertension in HCV Cirrhotic Patients Treated With New Antiviral Drugs (SPLEEN-C)
 

Status: Recruiting

Condition Summary: Chronic Hepatitis C; Cirrhosis; Portal Hypertension

 

Last Updated: 6 May 2015

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Value of Von Willebrand Factor in Portal Hypertension
 

Status: Recruiting

Condition Summary: Liver Cirrhosis; Portal Hypertension

 

Last Updated: 12 Jan 2015

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