Portal hypertension

Common Name(s)

Portal hypertension

Portal hypertension is abnormally high blood pressure in branches of the portal vein, the large vein that brings blood from the intestine to the liver. Portal hypertension itself does not cause symptoms, but complications from the condition can lead to an enlarged abdomen, abdominal discomfort, confusion, drowsiness and internal bleeding. It may be caused by a variety of conditions, but cirrhosis is the most common cause in Western countries. Treatment is generally directed toward the cause of the condition, although emergency treatment is sometimes needed for serious complications.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Portal hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Portal hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Portal hypertension" returned 617 free, full-text research articles on human participants. First 3 results:

The VITRO Score (Von Willebrand Factor Antigen/Thrombocyte Ratio) as a New Marker for Clinically Significant Portal Hypertension in Comparison to Other Non-Invasive Parameters of Fibrosis Including ELF Test.
 

Author(s): Stephanie Hametner, Arnulf Ferlitsch, Monika Ferlitsch, Alexandra Etschmaier, Rainer Schöfl, Alexander Ziachehabi, Andreas Maieron

Journal:

 

Clinically significant portal hypertension (CSPH), defined as hepatic venous pressure gradient (HVPG) ≥10 mmHg, causes major complications. HVPG is not always available, so a non-invasive tool to diagnose CSPH would be useful. VWF-Ag can be used to diagnose. Using the VITRO score ...

Last Updated: 20 Feb 2016

Go To URL
Efficacy of covered and bare stent in TIPS for cirrhotic portal hypertension: A single-center randomized trial.
 

Author(s): Lei Wang, Zhibo Xiao, Zhendong Yue, Hongwei Zhao, Zhenhua Fan, Mengfei Zhao, Fuliang He, Shan Dai, Bin Qiu, Jiannan Yao, Qiushi Lin, Xiaoqun Dong, Fuquan Liu

Journal:

 

We conducted a single-center randomized trial to compare the efficacy of 8 mm Fluency covered stent and bare stent in transjugular intrahepatic portosystemic shunt (TIPS) for cirrhotic portal hypertension. From January 2006 to December 2010, the covered (experimental group) or bare ...

Last Updated: 15 Feb 2016

Go To URL
Liver and spleen transient elastography predicts portal hypertension in patients with chronic liver disease: a prospective cohort study.
 

Author(s): Romanas Zykus, Laimas Jonaitis, Vitalija Petrenkienė, Andrius Pranculis, Limas Kupčinskas

Journal:

 

To assess correlation between liver or spleen stiffness measurement by transient elastography (TE) and hepatic venous pressure gradient (HVPG) in patients with chronic liver disease as well find optimal and rule in/rule out cut-offs for prognosis of clinically significant (CSPH) and ...

Last Updated: 25 Dec 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Portal hypertension" returned 119 free, full-text review articles on human participants. First 3 results:

Angiogenesis and portal-systemic collaterals in portal hypertension.
 

Author(s): Juan Cristóbal Gana, Carolina A Serrano, Simon C Ling

Journal: Ann Hepatol. ;15(3):303-13.

 

In patients with advanced liver disease with portal hypertension, portal-systemic collaterals contribute to circulatory disturbance, gastrointestinal hemorrhage, hepatic encephalopathy, ascites, hepatopulmonary syndrome and portopulmonary hypertension. Angiogenesis has a pivotal role ...

Last Updated: 7 Apr 2016

Go To URL
Liver surgery in cirrhosis and portal hypertension.
 

Author(s): Christina Hackl, Hans J Schlitt, Philipp Renner, Sven A Lang

Journal: World J. Gastroenterol.. 2016 Mar;22(9):2725-35.

 

The prevalence of hepatic cirrhosis in Europe and the United States, currently 250 patients per 100000 inhabitants, is steadily increasing. Thus, we observe a significant increase in patients with cirrhosis and portal hypertension needing liver resections for primary or metastatic ...

Last Updated: 14 Mar 2016

Go To URL
Ultrasound-based elastography for the diagnosis of portal hypertension in cirrhotics.
 

Author(s): Roxana Şirli, Ioan Sporea, Alina Popescu, Mirela Dănilă

Journal: World J. Gastroenterol.. 2015 Nov;21(41):11542-51.

 

Progressive fibrosis is encountered in almost all chronic liver diseases. Its clinical signs are diagnostic in advanced cirrhosis, but compensated liver cirrhosis is harder to diagnose. Liver biopsy is still considered the reference method for staging the severity of fibrosis, but ...

Last Updated: 11 Nov 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Low-grade Cirrhotic Portal Hypertension Due to Hepatitis B Virus With Fuzheng Huayu and Entecavir
 

Status: Not yet recruiting

Condition Summary: Portal Hypertension

 

Last Updated: 24 Oct 2016

Go to URL

Last Updated: 24 Oct 2016

Go to URL

Last Updated: 2 Dec 2016

Go to URL