Portal hypertension

Common Name(s)

Portal hypertension

Portal hypertension is abnormally high blood pressure in branches of the portal vein, the large vein that brings blood from the intestine to the liver. Portal hypertension itself does not cause symptoms, but complications from the condition can lead to an enlarged abdomen, abdominal discomfort, confusion, drowsiness and internal bleeding. It may be caused by a variety of conditions, but cirrhosis is the most common cause in Western countries. Treatment is generally directed toward the cause of the condition, although emergency treatment is sometimes needed for serious complications.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Portal hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Portal hypertension" returned 598 free, full-text research articles on human participants. First 3 results:

Laparoscopic distal splenoadrenal shunt for the treatment of portal hypertension in children with congenital hepatic fibrosis: A case report.
 

Author(s): Jin-Shan Zhang, Wei Cheng, Long Li

Journal: Medicine (Baltimore). 2017 Jan;96(3):e5843.

 

The distal splenorenal shunt is an effective procedure for the treatment of portal hypertension in children. However, there has been no report about laparoscopic distal splenorenal shunt in the treatment of portal hypertension in children.

Last Updated: 18 Jan 2017

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Effects of asymmetric dimethylarginine on renal arteries in portal hypertension and cirrhosis.
 

Author(s): Gloria Segarra, Belén Cortina, María Dolores Mauricio, Susana Novella, Paloma Lluch, Javier Navarrete-Navarro, Inmaculada Noguera, Pascual Medina

Journal: World J. Gastroenterol.. 2016 Dec;22(48):10545-10556.

 

To evaluate the effects of asymmetric dimethylarginine (ADMA) in renal arteries from portal hypertensive and cirrhotic rats.

Last Updated: 13 Jan 2017

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Portal hypertension in polycystic liver disease patients does not affect wait-list or immediate post-liver transplantation outcomes.
 

Author(s): Neil Rajoriya, Dhiraj Tripathi, Joanna A Leithead, Bridget K Gunson, Sophie Lord, James W Ferguson, Gideon M Hirschfield

Journal: World J. Gastroenterol.. 2016 Dec;22(45):9966-9973.

 

To establish the impact of portal hypertension (PH) on wait-list/post-transplant outcomes in patients with polycystic liver disease (PCLD) listed for liver transplantation.

Last Updated: 26 Dec 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Portal hypertension" returned 118 free, full-text review articles on human participants. First 3 results:

Case report and systematic literature review of a novel etiology of sinistral portal hypertension presenting with UGI bleeding: Left gastric artery pseudoaneurysm compressing the splenic vein treated by embolization of the pseudoaneurysm.
 

Author(s): Seifeldin Hakim, Jared Bortman, Molly Orosey, Mitchell S Cappell

Journal: Medicine (Baltimore). 2017 Mar;96(13):e6413.

 

A novel case is reported of upper gastrointestinal (UGI) bleeding from sinistral portal hypertension, caused by a left gastric artery (LGA) pseudoaneurysm (PA) compressing the splenic vein (SV) that was successfully treated with PA embolization.

Last Updated: 29 Mar 2017

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Transient elastography versus hepatic venous pressure gradient for diagnosing portal hypertension: a systematic review and meta-analysis.
 

Author(s): Gaeun Kim, Moon Young Kim, Soon Koo Baik

Journal: Clin Mol Hepatol. 2017 Mar;23(1):34-41.

 

Transient elastography (TE) has been proposed as a promising noninvasive alternative to hepatic venous pressure gradient (HVPG) for detecting portal hypertension (PH). However, previous studies have yielded conflicting results. We gathered evidence from literature on the clinical ...

Last Updated: 6 Mar 2017

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[Acute Kidney Injury in Cirrhotic Patients with Portal Hypertension].
 

Author(s): So Mi Kim, Il Han Song

Journal: Korean J Gastroenterol. 2016 Nov;68(5):237-244.

 

Acute kidney injury (AKI) is one of the most common manifestations encountered in clinical practice. It is associated with high morbidity and mortality in cirrhotic pre- and post-transplantation patients. Hepatorenal syndrome (HRS), a special form of AKI in cirrhotic patients, was ...

Last Updated: 22 Nov 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Low-grade Cirrhotic Portal Hypertension Due to Hepatitis B Virus With Fuzheng Huayu and Entecavir
 

Status: Not yet recruiting

Condition Summary: Portal Hypertension

 

Last Updated: 24 Oct 2016

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Last Updated: 24 Oct 2016

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Utility of EUS-elastography to Predict Portal Hypertension
 

Status: Recruiting

Condition Summary: Portal Hypertension

 

Last Updated: 13 May 2017

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