Portal hypertension

Common Name(s)

Portal hypertension

Portal hypertension is abnormally high blood pressure in branches of the portal vein, the large vein that brings blood from the intestine to the liver. Portal hypertension itself does not cause symptoms, but complications from the condition can lead to an enlarged abdomen, abdominal discomfort, confusion, drowsiness and internal bleeding. It may be caused by a variety of conditions, but cirrhosis is the most common cause in Western countries. Treatment is generally directed toward the cause of the condition, although emergency treatment is sometimes needed for serious complications.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Portal hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Portal hypertension" returned 459 free, full-text research articles on human participants. First 3 results:

Comparison of effects of devascularization versus shunt on patients with portal hypertension: a meta-analysis.
 

Author(s): G-Q Zong, Y Fei, R-M Liu

Journal: Chirurgia (Bucur). ;110(1):15-25.

 

To systematically evaluate the effectiveness of devascularization and shunt on patients with portal hypertension.

Last Updated: 24 Mar 2015

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Development of nodular regenerative hyperplasia (NRH) with portal hypertension following the administration of oxaliplatin for the recurrence of colon cancer.
 

Author(s): Hiroaki Takaya, Hideto Kawaratani, Keisuke Nakanishi, Shinya Takeyama, Chie Morioka, Masayoshi Sawai, Masahisa Toyohara, Masao Fujimoto, Hitoshi Yoshiji, Junichi Yamao, Hiroshi Fukui

Journal: Intern. Med.. 2015 ;54(4):383-7.

 

Nodular regenerative hyperplasia (NRH) is associated with autoimmune and hematologic diseases and may lead to portal hypertension. We herein report a case of NRH diagnosed based on a liver biopsy. A 63-year-old woman developed esophageal varices and splenomegaly. She had undergone ...

Last Updated: 9 Mar 2015

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[The impact of preoperative correction of coagulation disorders on massive abdominal bleeding during splenectomy plus perifundal devascularization for portal hypertension].
 

Author(s): Nan Zhang, Xinguang Qiu, Dongqiang Wang

Journal: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2014 Oct;26(10):755-6.

 

Last Updated: 15 Oct 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Portal hypertension" returned 93 free, full-text review articles on human participants. First 3 results:

Selection of a TIPS stent for management of portal hypertension in liver cirrhosis: an evidence-based review.
 

Author(s): Xing-Shun Qi, Ming Bai, Zhi-Ping Yang, Dai-Ming Fan

Journal: World J. Gastroenterol.. 2014 Jun;20(21):6470-80.

 

Nowadays, transjugular intrahepatic portosystemic shunt (TIPS) has become a mainstay treatment option for the management of portal hypertension-related complications in liver cirrhosis. Accumulated evidence has shown that its indications are being gradually expanded. Notwithstanding, ...

Last Updated: 10 Jun 2014

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Laparoscopic splenectomy for hypersplenism secondary to liver cirrhosis and portal hypertension.
 

Author(s): Xiao-Li Zhan, Yun Ji, Yue-Dong Wang

Journal: World J. Gastroenterol.. 2014 May;20(19):5794-800.

 

Since the first laparoscopic splenectomy (LS) was reported in 1991, LS has become the gold standard for the removal of normal to moderately enlarged spleens in benign conditions. Compared with open splenectomy, fewer postsurgical complications and better postoperative recovery have ...

Last Updated: 10 Jun 2014

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Therapeutic potential of microRNA: a new target to treat intrahepatic portal hypertension?
 

Author(s): Can-Jie Guo, Qin Pan, Hua Xiong, Yu-Qi Qiao, Zhao-Lian Bian, Wei Zhong, Li Sheng, Hai Li, Lei Shen, Jing Hua, Xiong Ma

Journal: Biomed Res Int. 2014 ;2014():797898.

 

Intrahepatic portal hypertension accounts for most of the morbidity and mortality encountered in patients with liver cirrhosis, due to increased portal inflow and intrahepatic vascular resistance. Most treatments have focused only on portal inflow or vascular resistance. However, ...

Last Updated: 9 May 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

MRI in Portal Hypertension
 

Status: Recruiting

Condition Summary: Portal Hypertension

 

Last Updated: 14 Jan 2014

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Transient Elastography to Assess Liver Fibrosis and Portal Hypertension in HCV Cirrhotic Patients Treated With New Antiviral Drugs (SPLEEN-C)
 

Status: Recruiting

Condition Summary: Chronic Hepatitis C; Cirrhosis; Portal Hypertension

 

Last Updated: 6 May 2015

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Value of Von Willebrand Factor in Portal Hypertension
 

Status: Recruiting

Condition Summary: Liver Cirrhosis; Portal Hypertension

 

Last Updated: 12 Jan 2015

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