Portal hypertension

Common Name(s)

Portal hypertension

Portal hypertension is abnormally high blood pressure in branches of the portal vein, the large vein that brings blood from the intestine to the liver. Portal hypertension itself does not cause symptoms, but complications from the condition can lead to an enlarged abdomen, abdominal discomfort, confusion, drowsiness and internal bleeding. It may be caused by a variety of conditions, but cirrhosis is the most common cause in Western countries. Treatment is generally directed toward the cause of the condition, although emergency treatment is sometimes needed for serious complications.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Portal hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Portal hypertension" returned 620 free, full-text research articles on human participants. First 3 results:

The VITRO Score (Von Willebrand Factor Antigen/Thrombocyte Ratio) as a New Marker for Clinically Significant Portal Hypertension in Comparison to Other Non-Invasive Parameters of Fibrosis Including ELF Test.
 

Author(s): Stephanie Hametner, Arnulf Ferlitsch, Monika Ferlitsch, Alexandra Etschmaier, Rainer Schöfl, Alexander Ziachehabi, Andreas Maieron

Journal:

 

Clinically significant portal hypertension (CSPH), defined as hepatic venous pressure gradient (HVPG) ≥10 mmHg, causes major complications. HVPG is not always available, so a non-invasive tool to diagnose CSPH would be useful. VWF-Ag can be used to diagnose. Using the VITRO score ...

Last Updated: 20 Feb 2016

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Liver and spleen transient elastography predicts portal hypertension in patients with chronic liver disease: a prospective cohort study.
 

Author(s): Romanas Zykus, Laimas Jonaitis, Vitalija Petrenkienė, Andrius Pranculis, Limas Kupčinskas

Journal:

 

To assess correlation between liver or spleen stiffness measurement by transient elastography (TE) and hepatic venous pressure gradient (HVPG) in patients with chronic liver disease as well find optimal and rule in/rule out cut-offs for prognosis of clinically significant (CSPH) and ...

Last Updated: 25 Dec 2015

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Combined transjugular intrahepatic portosystemic shunt and other interventions for hepatocellular carcinoma with portal hypertension.
 

Author(s): Bin Qiu, Meng-Fei Zhao, Zhen-Dong Yue, Hong-Wei Zhao, Lei Wang, Zhen-Hua Fan, Fu-Liang He, Shan Dai, Jian-Nan Yao, Fu-Quan Liu

Journal: World J. Gastroenterol.. 2015 Nov;21(43):12439-47.

 

To evaluate combination transjugular intrahepatic portosystemic shunt (TIPS) and other interventions for hepatocellular carcinoma (HCC) and portal hypertension.

Last Updated: 25 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Portal hypertension" returned 116 free, full-text review articles on human participants. First 3 results:

Ultrasound-based elastography for the diagnosis of portal hypertension in cirrhotics.
 

Author(s): Roxana Şirli, Ioan Sporea, Alina Popescu, Mirela Dănilă

Journal: World J. Gastroenterol.. 2015 Nov;21(41):11542-51.

 

Progressive fibrosis is encountered in almost all chronic liver diseases. Its clinical signs are diagnostic in advanced cirrhosis, but compensated liver cirrhosis is harder to diagnose. Liver biopsy is still considered the reference method for staging the severity of fibrosis, but ...

Last Updated: 11 Nov 2015

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Contemporary concepts of the medical therapy of portal hypertension under liver cirrhosis.
 

Author(s): Dmitry Victorovich Garbuzenko

Journal: World J. Gastroenterol.. 2015 May;21(20):6117-26.

 

Severe complications of liver cirrhosis are mostly related to portal hypertension. At the base of the pathogenesis of portal hypertension is the increase in hepatic vascular resistance to portal blood flow with subsequent development of hyperdynamic circulation, which, despite of ...

Last Updated: 2 Jun 2015

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Idiopathic non-cirrhotic portal hypertension: a review.
 

Author(s): Jeoffrey N L Schouten, Joanne Verheij, Susana Seijo

Journal:

 

Idiopathic non-cirrhotic portal hypertension (INCPH) is a rare disease characterized of intrahepatic portal hypertension in the absence of cirrhosis or other causes of liver disease and splanchnic venous thrombosis. The etiology of INCPH can be classified in five categories: 1) immunological ...

Last Updated: 6 Jun 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Low-grade Cirrhotic Portal Hypertension Due to Hepatitis B Virus With Fuzheng Huayu and Entecavir
 

Status: Not yet recruiting

Condition Summary: Portal Hypertension

 

Last Updated: 24 Oct 2016

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Last Updated: 24 Oct 2016

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Last Updated: 23 Nov 2016

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