Portal hypertension

Common Name(s)

Portal hypertension

Portal hypertension is abnormally high blood pressure in branches of the portal vein, the large vein that brings blood from the intestine to the liver. Portal hypertension itself does not cause symptoms, but complications from the condition can lead to an enlarged abdomen, abdominal discomfort, confusion, drowsiness and internal bleeding. It may be caused by a variety of conditions, but cirrhosis is the most common cause in Western countries. Treatment is generally directed toward the cause of the condition, although emergency treatment is sometimes needed for serious complications.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Portal hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Portal hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Portal hypertension" returned 614 free, full-text research articles on human participants. First 3 results:

Laparoscopic distal splenoadrenal shunt for the treatment of portal hypertension in children with congenital hepatic fibrosis: A case report.
 

Author(s): Jin-Shan Zhang, Wei Cheng, Long Li

Journal: Medicine (Baltimore). 2017 Jan;96(3):e5843.

 

The distal splenorenal shunt is an effective procedure for the treatment of portal hypertension in children. However, there has been no report about laparoscopic distal splenorenal shunt in the treatment of portal hypertension in children.

Last Updated: 18 Jan 2017

Go To URL
Portosystemic Shunt Surgery in Patients with Idiopathic Noncirrhotic Portal Hypertension.
 

Author(s): Servet Karagul, Mehmet Ali Yagci, Ali Tardu, Ismail Ertugrul, Serdar Kirmizi, Fatih Sumer, Burak Isik, Cuneyt Kayaalp, Sezai Yilmaz

Journal:

 

BACKGROUND Idiopathic noncirrhotic portal hypertension (INCPH) is a rare disease characterized by increased portal venous pressure in the absence of cirrhosis and other causes of liver diseases. The aim of the present study was to present our results in using portosystemic shunt surgery ...

Last Updated: 19 May 2016

Go To URL
Osteopontin: A non-invasive parameter of portal hypertension and prognostic marker of cirrhosis.
 

Author(s): Radan Bruha, Marie Jachymova, Jaromir Petrtyl, Karel Dvorak, Martin Lenicek, Petr Urbanek, Tomislav Svestka, Libor Vitek

Journal: World J. Gastroenterol.. 2016 Mar;22(12):3441-50.

 

To investigate the relationship between osteopontin plasma concentrations and the severity of portal hypertension and to assess osteopontin prognostic value.

Last Updated: 29 Mar 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Portal hypertension" returned 117 free, full-text review articles on human participants. First 3 results:

Angiogenesis and portal-systemic collaterals in portal hypertension.
 

Author(s): Juan Cristóbal Gana, Carolina A Serrano, Simon C Ling

Journal: Ann Hepatol. ;15(3):303-13.

 

In patients with advanced liver disease with portal hypertension, portal-systemic collaterals contribute to circulatory disturbance, gastrointestinal hemorrhage, hepatic encephalopathy, ascites, hepatopulmonary syndrome and portopulmonary hypertension. Angiogenesis has a pivotal role ...

Last Updated: 7 Apr 2016

Go To URL
Liver surgery in cirrhosis and portal hypertension.
 

Author(s): Christina Hackl, Hans J Schlitt, Philipp Renner, Sven A Lang

Journal: World J. Gastroenterol.. 2016 Mar;22(9):2725-35.

 

The prevalence of hepatic cirrhosis in Europe and the United States, currently 250 patients per 100000 inhabitants, is steadily increasing. Thus, we observe a significant increase in patients with cirrhosis and portal hypertension needing liver resections for primary or metastatic ...

Last Updated: 14 Mar 2016

Go To URL
Ultrasound-based elastography for the diagnosis of portal hypertension in cirrhotics.
 

Author(s): Roxana Şirli, Ioan Sporea, Alina Popescu, Mirela Dănilă

Journal: World J. Gastroenterol.. 2015 Nov;21(41):11542-51.

 

Progressive fibrosis is encountered in almost all chronic liver diseases. Its clinical signs are diagnostic in advanced cirrhosis, but compensated liver cirrhosis is harder to diagnose. Liver biopsy is still considered the reference method for staging the severity of fibrosis, but ...

Last Updated: 11 Nov 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Low-grade Cirrhotic Portal Hypertension Due to Hepatitis B Virus With Fuzheng Huayu and Entecavir
 

Status: Not yet recruiting

Condition Summary: Portal Hypertension

 

Last Updated: 24 Oct 2016

Go to URL

Last Updated: 24 Oct 2016

Go to URL

Last Updated: 2 Dec 2016

Go to URL