Polymyositis

Common Name(s)

Polymyositis

Polymyositis is one of a group of muscle diseases known as the inflammatory myopathies, which are characterized by chronic muscle inflammation accompanied by muscle weakness.  Polymyositis affects skeletal muscles (those involved with making movement) on both sides of the body.  It is rarely seen in persons under age 18; most cases are seen in adults between the ages of 31 and 60. The cause of polymyositis is not fully understood.  Although there's no cure for polymyositis, treatment can improve muscle strength and function.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polymyositis" for support, advocacy or research.

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Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

Last Updated: 15 Jul 2015

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

Last Updated: 14 Jan 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polymyositis" for support, advocacy or research.

Logo
Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

http://www.mdausa.org

Last Updated: 15 Jul 2015

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

http://www.myositis.org

Last Updated: 14 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Polymyositis" returned 366 free, full-text research articles on human participants. First 3 results:

Effects of exercise therapy on polymyositis complicated by post-myocarditis cardiomyopathy: A case report.
 

Author(s): Hidetoshi Yanagi, Naohisa Shindo

Journal: J Rehabil Med. 2017 Mar;49(3):282-285.

 

A 42-year-old woman with chronic polymyositis complicated by post-myocarditis cardiomyopathy underwent supervised and unsupervised exercise therapy with staged increases in intensity.

Last Updated: 20 Feb 2017

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Identification of Palmitoleic Acid Controlled by mTOR Signaling as a Biomarker of Polymyositis.
 

Author(s): Geng Yin, Ying Wang, Xiao-Min Cen, Yuan Yang, Min Yang, Qi-Bing Xie

Journal: J Immunol Res. 2017 ;2017():3262384.

 

Polymyositis (PM) is a chronic disease characterized by muscle pain, weakness, and increase in muscle-related enzymes, accompanied with inflammations in lymphocytes. However, it is not well understood how the molecular alternations in lymphocytes contribute to the development of polymyositis. ...

Last Updated: 14 Feb 2017

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Atorvastatin-induced necrotizing autoimmune myositis: An emerging dominant entity in patients with autoimmune myositis presenting with a pure polymyositis phenotype.
 

Author(s): Yves Troyanov, Océane Landon-Cardinal, Marvin J Fritzler, José Ferreira, Ira N Targoff, Eric Rich, Michelle Goulet, Jean-Richard Goulet, Josiane Bourré-Tessier, Yves Robitaille, Julie Drouin, Alexandra Albert, Jean-Luc Senécal

Journal: Medicine (Baltimore). 2017 Jan;96(3):e5694.

 

The general aim of this study was to evaluate the disease spectrum in patients presenting with a pure polymyositis (pPM) phenotype. Specific objectives were to characterize clinical features, autoantibodies (aAbs), and membrane attack complex (MAC) in muscle biopsies of patients with ...

Last Updated: 18 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Polymyositis" returned 38 free, full-text review articles on human participants. First 3 results:

Factors Associated with Interstitial Lung Disease in Patients with Polymyositis and Dermatomyositis: A Systematic Review and Meta-Analysis.
 

Author(s): Li Zhang, Guoqin Wu, Di Gao, Guijian Liu, Lin Pan, Liyan Ni, Zheng Li, Qiang Wang

Journal:

 

Interstitial lung disease (ILD) is an extramuscular manifestation that results in increased morbidity and mortality from polymyositis (PM) and dermatomyositis (DM). The aim of this study was to systematically evaluate risk factors associated with the development of ILD in PM/DM.

Last Updated: 13 May 2016

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Polymyositis in a patient with ulcerative colitis.
 

Author(s): Andrés González García, Walter Alberto Sifuentes-Giraldo, Sergio Diz Fariña, Héctor Pian

Journal: Reumatol Clin. ;12(6):360-362.

 

Last Updated: 1 Apr 2016

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Polymyositis and dermatomyositis: novel insights into the pathogenesis and potential therapeutic targets.
 

Author(s): Arash H Lahouti, Lisa Christopher-Stine

Journal: Discov Med. 2015 Jun;19(107):463-70.

 

Polymyositis (PM) and dermatomyositis (DM) are the two major forms of inflammatory muscle diseases. They are characterized clinically primarily by proximal muscle weakness. The disease mechanisms that cause muscle damage and dysfunction are not fully understood. However, because of ...

Last Updated: 16 Jul 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis
 

Status: Recruiting

Condition Summary: Dermatomyositis; Polymyositis

 

Last Updated: 26 Oct 2016

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Lipid-lowering Agents in Patients With Dermatomyositis and Polymyositis
 

Status: Recruiting

Condition Summary: Treatment Side Effects

 

Last Updated: 24 Mar 2017

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Investigating Genes in Patients With Polymyositis and Dermatomyositis
 

Status: Recruiting

Condition Summary: Myositis

 

Last Updated: 14 Oct 2016

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