Polymyositis

Common Name(s)

Polymyositis

Polymyositis is one of a group of muscle diseases known as the inflammatory myopathies, which are characterized by chronic muscle inflammation accompanied by muscle weakness.  Polymyositis affects skeletal muscles (those involved with making movement) on both sides of the body.  It is rarely seen in persons under age 18; most cases are seen in adults between the ages of 31 and 60. The cause of polymyositis is not fully understood.  Although there's no cure for polymyositis, treatment can improve muscle strength and function.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polymyositis" for support, advocacy or research.

Logo
Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

Last Updated: 8 Mar 2010

View Details
Logo
The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

Last Updated: 14 Jan 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polymyositis" for support, advocacy or research.

Logo
Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

http://www.mdausa.org

Last Updated: 8 Mar 2010

View Details
Logo
The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

http://www.myositis.org

Last Updated: 14 Jan 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Polymyositis" returned 326 free, full-text research articles on human participants. First 3 results:

Polymyositis with myotonia in a patient with common variable immunodefi ciency.
 

Author(s): Ying Li, Wei Zhang, L Q Feng, Yun Yuan

Journal: Neurol India. ;62(1):68-70.

 

Last Updated: 10 Mar 2014

Go To URL
Cardiac metastasis and tumor embolism in a patient with adenocarcinoma of the colon presenting with paraneoplastic polymyositis.
 

Author(s): E Mihali, Mihaela Mureşan, M L Rusu, Daniela Fodor

Journal: Rom J Morphol Embryol. 2013 ;54(3 Suppl):897-900.

 

Colorectal cancer usually presents with alterations in the bowel habit. Less commonly, the presenting symptoms may be part of a paraneoplastic syndrome. Metastasis can occur by lymphatic or hematogenous spread, most frequently to the lungs and liver. We present the case of a 56-year-old ...

Last Updated: 10 Dec 2013

Go To URL
Suppression of soluble T cell-associated proteins by an anti-interferon-α monoclonal antibody in adult patients with dermatomyositis or polymyositis.
 

Author(s): Xiang Guo, Brandon W Higgs, Marlon Rebelatto, Wei Zhu, Warren Greth, Yihong Yao, Lorin K Roskos, Wendy I White

Journal: Rheumatology (Oxford). 2014 Apr;53(4):686-95.

 

The aim of this study was to identify serum markers that are modulated by an investigational anti-IFN-α mAb, sifalimumab, in adult DM or PM patients.

Last Updated: 21 Mar 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Polymyositis" returned 31 free, full-text review articles on human participants. First 3 results:

The concurrent association of inflammatory polymyositis and Crohn's ileo-colitis in a Sri Lankan man: a case report of a rare association and literature review.
 

Author(s): Vipula R Bataduwaarachchi, Nilesh Fenandopulle, Upul Liyanage, Champa Jayasundara

Journal:

 

Crohn's disease is a relapsing, systemic inflammatory disease affecting the gastrointestinal tract with associated extraintestinal manifestations and immune disorders. Among the few cases reported, the association of Crohn's disease with polymyositis varies in its complexity and severity. ...

Last Updated: 3 Mar 2014

Go To URL
Dermatomyositis and polymyositis: from immunopathology to immunotherapy (immunobiologics).
 

Author(s): Samuel Katsuyuki Shinjo, Fernando Henrique Carlos de Souza, Julio Cesar Bertacini de Moraes

Journal: Rev Bras Reumatol. 2013 Feb;53(1):101-10.

 

Idiopathic inflammatory myopathies (IIM), which include dermatomyositis (DM) and polymyositis (PM), are chronic systemic diseases associated with high morbidity and functional disability. Current treatment is based on the use of glucocorticoids and immunosuppressive drugs, but a considerable ...

Last Updated: 16 Apr 2013

Go To URL
Pancreas cancer-associated polymyositis of the legs regressing after cephalic duodenopancreatectomy: case report and review of the literature.
 

Author(s): Koceila Lamine Amroun, Louis De Mestier, Sophie Deguelte-Lardiere, Marie-Danièle Diebold, Olivier Bouché, Reza Kianmanesh

Journal:

 

Inflammatory myopathy, such as polymyositis, has been widely reported as paraneoplastic syndrome associated with various malignancies. However, its association with pancreas adenocarcinoma is very uncommon.

Last Updated: 27 Nov 2012

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis
 

Status: Recruiting

Condition Summary: Dermatomyositis; Polymyositis

 

Last Updated: 29 Oct 2014

Go to URL
Acthar in Treatment of Refractory Dermatomyositis and Polymyositis
 

Status: Recruiting

Condition Summary: Dermatomyositis; Polymyositis

 

Last Updated: 6 Feb 2014

Go to URL
Efficacy and Tolerability of BAF312 in Patients With Polymyositis
 

Status: Recruiting

Condition Summary: Polymyositis

 

Last Updated: 5 Nov 2014

Go to URL