Polymyositis

Common Name(s)

Polymyositis

Polymyositis is one of a group of muscle diseases known as the inflammatory myopathies, which are characterized by chronic muscle inflammation accompanied by muscle weakness.  Polymyositis affects skeletal muscles (those involved with making movement) on both sides of the body.  It is rarely seen in persons under age 18; most cases are seen in adults between the ages of 31 and 60. The cause of polymyositis is not fully understood.  Although there's no cure for polymyositis, treatment can improve muscle strength and function.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polymyositis" for support, advocacy or research.

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Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

Last Updated: 15 Jul 2015

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

Last Updated: 14 Jan 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polymyositis" for support, advocacy or research.

Logo
Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

http://www.mdausa.org

Last Updated: 15 Jul 2015

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

http://www.myositis.org

Last Updated: 14 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Polymyositis" returned 375 free, full-text research articles on human participants. First 3 results:

Treatment of Fulminant Giant Cell Myocarditis Associated with Polymyositis Using a Left Ventricular Assist Device and Subsequent Corticosteroid and Immunosuppressive Therapy Leading to Remission.
 

Author(s): Junichi Ooka, Hidekazu Tanaka, Yutaka Hatani, Yukio Tsuji, Ryo Takeshige, Shumpei Mori, Kensuke Matsumoto, Shigeo Hara, Hiroshi Tanaka, Yutaka Okita, Ken-Ichi Hirata

Journal: Intern. Med.. 2017 Aug;56(16):2155-2158.

 

A 58-year-old man with a recent history of generalized myalgia and muscle weakness was transferred to our hospital because of acute progressive dyspnea. The patient underwent left ventricular (LV) assist device (LVAD) implantation due to cardiogenic shock with a LV ejection fraction ...

Last Updated: 31 Dec 1969

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Progressive hypoventilation due to mixed CD8and CD4lymphocytic polymyositis following tremelimumab - durvalumab treatment.
 

Author(s): Sooraj John, Scott J Antonia, Trevor A Rose, Robert P Seifert, Barbara A Centeno, Aaron S Wagner, Ben C Creelan

Journal:

 

The combination of CTLA-4 and PD-L1 inhibitors has a manageable adverse effect profile, although rare immune-related adverse events (irAE) can occur.

Last Updated: 31 Dec 1969

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An efficacy analysis of whole-body magnetic resonance imaging in the diagnosis and follow-up of polymyositis and dermatomyositis.
 

Author(s): Zhen-Guo Huang, Bao-Xiang Gao, He Chen, Min-Xing Yang, Xiao-Liang Chen, Ran Yan, Xin Lu, Kai-Ning Shi, Queenie Chan, Guo-Chun Wang

Journal:

 

To evaluate the value of whole-body magnetic resonance imaging (WBMRI) in diagnosing muscular and extra muscular lesions in patients with polymyositis (PM) and dermatomyositis (DM).

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Polymyositis" returned 39 free, full-text review articles on human participants. First 3 results:

Polymyositis with elevated serum IgG4 levels and abundant IgG4+ plasma cell infiltration: A case report and literature review.
 

Author(s): Ryusuke Anan, Mitsuhiro Akiyama, Yuko Kaneko, Jun Kikuchi, Kazuko Suzuki, Shiro Matsubara, Tsutomu Takeuchi

Journal: Medicine (Baltimore). 2017 Dec;96(48):e8710.

 

Polymyositis (PM) is a type of autoimmune, inflammatory myopathy. IgG4-related disease (IgG4-RD) is a recently recognized disease entity characterized by elevated serum IgG4 levels and IgG4 plasma-cell infiltration of various organs. However, several reports have described cases of ...

Last Updated: 31 Dec 1969

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Factors Associated with Interstitial Lung Disease in Patients with Polymyositis and Dermatomyositis: A Systematic Review and Meta-Analysis.
 

Author(s): Li Zhang, Guoqin Wu, Di Gao, Guijian Liu, Lin Pan, Liyan Ni, Zheng Li, Qiang Wang

Journal:

 

Interstitial lung disease (ILD) is an extramuscular manifestation that results in increased morbidity and mortality from polymyositis (PM) and dermatomyositis (DM). The aim of this study was to systematically evaluate risk factors associated with the development of ILD in PM/DM.

Last Updated: 31 Dec 1969

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Polymyositis in a patient with ulcerative colitis.
 

Author(s): Andrés González García, Walter Alberto Sifuentes-Giraldo, Sergio Diz Fariña, Héctor Pian

Journal: Reumatol Clin. ;12(6):360-362.

 

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis
 

Status: Recruiting

Condition Summary: Dermatomyositis; Polymyositis

 

Last Updated: 30 Oct 2017

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Effects of High-intensity Interval Training (HIIT) in Recent Onset Polymyositis and Dermatomyositis
 

Status: Not yet recruiting

Condition Summary: Polymyositis; Dermatomyositis

 

Last Updated: 24 Oct 2017

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Lipid-lowering Agents in Patients With Dermatomyositis and Polymyositis
 

Status: Recruiting

Condition Summary: Treatment Side Effects

 

Last Updated: 24 Mar 2017

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