Polycystic liver disease

Common Name(s)

Polycystic liver disease

Polycystic liver disease is an inherited condition characterized by many cysts of various sizes scattered throughout the liver. Abdominal discomfort from swelling of the liver may occur; however, most affected individuals do not have any symptoms. In some cases, polycystic liver disease appears to occur randomly, with no apparent cause. Most cases are inherited in an autosomal dominant fashion. Sometimes, cysts are found in the liver in association with the presence of autosomal dominant polycystic kidney disease (AD-PKD). In fact, about half of the people who have AD-PKD experience liver cysts. However, kidney cysts are uncommon in those affected by polycystic liver disease.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polycystic liver disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Polycystic liver disease" returned 109 free, full-text research articles on human participants. First 3 results:

Increased prevalence of polycystic ovary syndrome in premenopausal women with nonalcoholic fatty liver disease.
 

Author(s): E Vassilatou, D A Vassiliadi, K Salambasis, H Lazaridou, N Koutsomitopoulos, N Kelekis, D Kassanos, D Hadjidakis, G Dimitriadis

Journal: Eur. J. Endocrinol.. 2015 Dec;173(6):739-47.

 

Limited data exist concerning the presence of polycystic ovary syndrome (PCOS) in premenopausal women with nonalcoholic fatty liver disease (NAFLD). We aimed to investigate the prevalence of PCOS in overweight and obese premenopausal women with NAFLD.

Last Updated: 27 Oct 2015

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Hepatic Intracystic Organizing Hematoma Mimicking Biliary Cystadenocarcinoma in a Patient with Polycystic Liver Disease.
 

Author(s): Takashi Tanaka, Hideo Gobara, Koji Tomita, Takao Hiraki, Takehiro Tanaka, Susumu Kanazawa

Journal: Intern. Med.. 2015 ;54(16):2001-5.

 

Hepatic intracystic hemorrhage is a rare complication of polycystic liver diseases, such as autosomal dominant polycystic kidney disease (ADPKD). A hepatic cyst with mural nodules and septation may suggest the presence of a cystic malignancy, such as biliary cystadenocarcinoma. We ...

Last Updated: 17 Aug 2015

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Hepatocellular Carcinoma in a Patient with Polycystic Liver Disease.
 

Author(s): Masahiro Kawada, Noriko Hayami, Tatsuya Suwabe, Junichi Hoshino, Keiichi Sumida, Koki Mise, Satoshi Hamanoue, Masayuki Yamanouchi, Naoki Sawa, Kenmei Takaichi, Takeshi Fujii, Yoshifumi Ubara

Journal: Intern. Med.. 2015 ;54(15):1891-6.

 

A 49-year-old Japanese woman with polycystic liver disease (PLD) was admitted for right hypochondrial pain. CT showed a huge enhancing mass in the liver. She tested negative for other liver diseases, such as hepatitis B and C and alcoholic liver disease. After the patient expired ...

Last Updated: 3 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Polycystic liver disease" returned 13 free, full-text review articles on human participants. First 3 results:

Review of nonalcoholic fatty liver disease in women with polycystic ovary syndrome.
 

Author(s): Carly E Kelley, Ann J Brown, Anna Mae Diehl, Tracy L Setji

Journal: World J. Gastroenterol.. 2014 Oct;20(39):14172-84.

 

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive-aged women. Women with PCOS frequently have metabolic complications including insulin resistance (IR), early diabetes, hypertension and dyslipidemia. Recent studies have demonstrated an association ...

Last Updated: 23 Oct 2014

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Nonalcoholic fatty liver disease and polycystic ovary syndrome.
 

Author(s): Evangeline Vassilatou

Journal: World J. Gastroenterol.. 2014 Jul;20(26):8351-63.

 

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the Western world comprising a spectrum of liver damage from fatty liver infiltration to end-stage liver disease, in patients without significant alcohol consumption. Increased prevalence ...

Last Updated: 15 Jul 2014

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Polycystic liver disease: an overview of pathogenesis, clinical manifestations and management.
 

Author(s): Wybrich R Cnossen, Joost P H Drenth

Journal:

 

Polycystic liver disease (PLD) is the result of embryonic ductal plate malformation of the intrahepatic biliary tree. The phenotype consists of numerous cysts spread throughout the liver parenchyma. Cystic bile duct malformations originating from the peripheral biliary tree are called ...

Last Updated: 4 Jun 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Development and Assessment of The Polycystic Liver Disease Questionnaire (PLD-Q).
 

Status: Recruiting

Condition Summary: Polycystic Liver Disease

 

Last Updated: 6 Apr 2015

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NAFLD in Adolescents and Young Adults With PCOS
 

Status: Recruiting

Condition Summary: Polycystic Ovary Syndrome; Non-Alcoholic Fatty Liver Disease; Metabolic Syndrome

 

Last Updated: 3 Nov 2016

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Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS)
 

Status: Recruiting

Condition Summary: Polycystic Ovary Syndrome; Non-Alcoholic Fatty Liver Disease; Metabolic Syndrome

 

Last Updated: 3 Nov 2016

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