Polycystic liver disease

Common Name(s)

Polycystic liver disease

Polycystic liver disease is an inherited condition characterized by many cysts of various sizes scattered throughout the liver. Abdominal discomfort from swelling of the liver may occur; however, most affected individuals do not have any symptoms. In some cases, polycystic liver disease appears to occur randomly, with no apparent cause. Most cases are inherited in an autosomal dominant fashion. Sometimes, cysts are found in the liver in association with the presence of autosomal dominant polycystic kidney disease (AD-PKD). In fact, about half of the people who have AD-PKD experience liver cysts. However, kidney cysts are uncommon in those affected by polycystic liver disease.

 

Advocacy and Support Organizations

 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polycystic liver disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Polycystic liver disease" returned 83 free, full-text research articles on human participants. First 3 results:

Last Updated: 20 Mar 2015

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Development and validation of a polycystic liver disease complaint-specific assessment (POLCA) - use of the Delphi technique for content validation.
 

Author(s): Daisson José Trevisol, Alexandre da Silva, Fabrício de Souza, Clávison Martinelli Zapelini

Journal: J. Hepatol.. 2015 Apr;62(4):988.

 

Last Updated: 20 Mar 2015

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Cyst infection in hospital-admitted autosomal dominant polycystic kidney disease patients is predominantly multifocal and associated with kidney and liver volume.
 

Author(s): B E P Balbo, M T Sapienza, C R Ono, S K Jayanthi, J B Dettoni, I Castro, L F Onuchic

Journal: Braz. J. Med. Biol. Res.. 2014 Jul;47(7):584-93.

 

Positron-emission tomography/computed tomography (PET/CT) has improved cyst infection (CI) management in autosomal dominant polycystic kidney disease (ADPKD). The determinants of kidney and/or liver involvement, however, remain uncertain. In this study, we evaluated clinical and imaging ...

Last Updated: 9 Jul 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Polycystic liver disease" returned 11 free, full-text review articles on human participants. First 3 results:

Review of nonalcoholic fatty liver disease in women with polycystic ovary syndrome.
 

Author(s): Carly E Kelley, Ann J Brown, Anna Mae Diehl, Tracy L Setji

Journal: World J. Gastroenterol.. 2014 Oct;20(39):14172-84.

 

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive-aged women. Women with PCOS frequently have metabolic complications including insulin resistance (IR), early diabetes, hypertension and dyslipidemia. Recent studies have demonstrated an association ...

Last Updated: 23 Oct 2014

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Nonalcoholic fatty liver disease and polycystic ovary syndrome.
 

Author(s): Evangeline Vassilatou

Journal: World J. Gastroenterol.. 2014 Jul;20(26):8351-63.

 

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the Western world comprising a spectrum of liver damage from fatty liver infiltration to end-stage liver disease, in patients without significant alcohol consumption. Increased prevalence ...

Last Updated: 15 Jul 2014

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Polycystic liver disease: an overview of pathogenesis, clinical manifestations and management.
 

Author(s): Wybrich R Cnossen, Joost P H Drenth

Journal:

 

Polycystic liver disease (PLD) is the result of embryonic ductal plate malformation of the intrahepatic biliary tree. The phenotype consists of numerous cysts spread throughout the liver parenchyma. Cystic bile duct malformations originating from the peripheral biliary tree are called ...

Last Updated: 4 Jun 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pasireotide LAR in Severe Polycystic Liver Disease
 

Status: Recruiting

Condition Summary: Somatostatin Analogs; Polycystic Liver Disease; Autosomal Dominant Polycystic Kidney Disease; Autosomal Dominant Polycystic Liver Disease

 

Last Updated: 6 Apr 2015

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Ursodeoxycholic Acid as Treatment for Polycystic Liver Disease
 

Status: Recruiting

Condition Summary: Polycystic Liver Disease (PLD):; Polycystic Kidney, Autosomal Dominant; Polycystic Liver Disease

 

Last Updated: 5 Nov 2014

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Development and Assessment of The Polycystic Liver Disease Questionnaire (PLD-Q).
 

Status: Recruiting

Condition Summary: Polycystic Liver Disease

 

Last Updated: 6 Apr 2015

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