Polyarteritis nodosa

Common Name(s)

Polyarteritis nodosa

Polyarteritis nodosa is a serious blood vessel disease in which medium-sized arteries become swollen and damaged. It occurs when certain immune cells attack the affected arteries preventing vital oxygen and nourishment. Signs and symptoms may include fever, fatigue, weakness, loss of appetite, weight loss, muscle and joint aches, and abdominal pain. The skin may show rashes, swelling, ulcers, and lumps. When nerve cells are involved numbness, pain, burning, and weakness may be present. Polyarteritis nodosa can cause serious health complications including strokes, seizures, and kidney failure. Treatment often includes steroids and other drugs to suppress the immune system.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polyarteritis nodosa" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Polyarteritis nodosa" returned 174 free, full-text research articles on human participants. First 3 results:

Minocycline-induced polyarteritis nodosa-like vasculitis.
 

Author(s): Timna Agur, Yair Levy, Eleonora Plotkin, Sydney Benchetrit

Journal: Isr. Med. Assoc. J.. 2014 May;16(5):322-3.

 

Last Updated: 1 Jul 2014

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Mutant adenosine deaminase 2 in a polyarteritis nodosa vasculopathy.
 

Author(s): Paulina Navon Elkan, Sarah B Pierce, Reeval Segel, Tom Walsh, Judith Barash, Shai Padeh, Abraham Zlotogorski, Yackov Berkun, Joseph J Press, Masha Mukamel, Isabel Voth, Philip J Hashkes, Liora Harel, Vered Hoffer, Eduard Ling, Fatos Yalcinkaya, Ozgur Kasapcopur, Ming K Lee, Rachel E Klevit, Paul Renbaum, Ariella Weinberg-Shukron, Elif F Sener, Barbara Schormair, Sharon Zeligson, Dina Marek-Yagel, Tim M Strom, Mordechai Shohat, Amihood Singer, Alan Rubinow, Elon Pras, Juliane Winkelmann, Mustafa Tekin, Yair Anikster, Mary-Claire King, Ephrat Levy-Lahad

Journal: N. Engl. J. Med.. 2014 Mar;370(10):921-31.

 

Polyarteritis nodosa is a systemic necrotizing vasculitis with a pathogenesis that is poorly understood. We identified six families with multiple cases of systemic and cutaneous polyarteritis nodosa, consistent with autosomal recessive inheritance. In most cases, onset of the disease ...

Last Updated: 6 Mar 2014

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Cardiac arrest in a patient with polyarteritis nodosa.
 

Author(s): Yuko Harada, Takahiro Suzuki, Toshihito Shinagawa, Tatsuji Yoshimoto

Journal: Intern. Med.. 2013 ;52(24):2759-63.

 

Polyarteritis nodosa (PAN) is a rare necrotizing vasculitis that occurs in small- to medium-sized muscular arteries. A 71-year-old man was admitted to our hospital for an evaluation of a sustained fever and he later died of cardiac arrest. The autopsy revealed that the patient had ...

Last Updated: 16 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Polyarteritis nodosa" returned 15 free, full-text review articles on human participants. First 3 results:

Acute kidney injury in a patient with polyarteritis nodosa and multiple myeloma.
 

Author(s): Kazuhiro Yokota, Tsutomu Inoue, Yuji Akiyama, Hiroshi Kajiyama, Yu Funakubo Asanuma, Eiichi Arai, Hiromichi Suzuki, Toshihide Mimura

Journal: Intern. Med.. 2014 ;53(3):263-7.

 

We herein report the case of a Japanese man with polyarteritis nodosa (PAN) accompanied by multiple myeloma (MM). The patient was diagnosed with PAN. Concurrently, IgG kappa paraprotein was detected, and bone marrow changes indicative of MM were observed. Prednisolone (PSL) administered ...

Last Updated: 4 Feb 2014

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Coil embolization of intracranial aneurysm in polyarteritis nodosa. A case report and review of the literature.
 

Author(s): V Gupta, S D Chinchure, G Goe, A N Jha, S Malviya, R Gupta

Journal: Interv Neuroradiol. 2013 Jun;19(2):203-8.

 

Polyarteritis nodosa (PAN) is a rare multisystem disease characterized by systemic necrotizing arteritis of small and medium size arteries. The skin, joints, kidneys, gastrointestinal tract and peripheral nerves are most commonly involved. Although aneurysms are commonly seen in the ...

Last Updated: 22 May 2013

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Polyarteritis nodosa diagnosed by surgically resected jejunal necrosis following acute abdomen.
 

Author(s): Yuta Hiraike, Makoto Kodaira, Munetaka Sano, Yasuyuki Terazawa, Shingo Yamagata, Syuzo Terada, Masaharu Ohura, Ken Kuriki

Journal: World J. Gastroenterol.. 2013 May;19(18):2830-4.

 

The differential diagnosis of acute abdomen is typically extremely broad in range, with vasculitis posing a rare but potentially life-threatening cause of acute abdomen. Here, we report a case of acute abdomen with bowel wall thickening limited to jejunum, accompanied by unexplained ...

Last Updated: 20 May 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Determining Disease Activity Biomarkers in Individuals With Polyarteritis Nodosa
 

Status: Recruiting

Condition Summary: Polyarteritis Nodosa

 

Last Updated: 22 Nov 2013

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Pediatric Vasculitis Initiative
 

Status: Recruiting

Condition Summary: Wegeners Granulomatosis (Granulomatosis With Polyangiitis); Microscopic Polyangiitis; Churg Strauss Syndrome (Eosinophilic Granulomatosis With Polyangiitis); Polyarteritis Nodosa; Takayasu Arteritis; Primary CNS Vasculitis; Unclassified Vasculitis

 

Last Updated: 25 Jul 2014

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American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) Diagnostic and Classification Criteria for Primary Systemic Vasculitis
 

Status: Recruiting

Condition Summary: Wegener's Granulomatosis; Microscopic Polyangiitis; Churg Strauss Syndrome; Polyarteritis Nodosa; Giant Cell Arteritis; Takayasu Arteritis

 

Last Updated: 3 Jun 2014

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