Poliomyelitis

Common Name(s)

Poliomyelitis, Polio

Poliomyelitis is a viral disease that can affect nerves and can lead to partial or full paralysis. It is caused by infection with the poliovirus which can be spread by direct person-to-person contact, by contact with infected mucus or phlegm from the nose or mouth, or by contact with infected feces. Since the development of polio vaccine, the incidence of the disease has been greatly reduced. There are three basic patterns of polio infection: subclinical infections, nonparalytic, and paralytic. Approximately 95% of infections are subclinical infections, which may not have symptoms. Clinical poliomyelitis affects the central nervous system (brain and spinal cord) and is divided into nonparalytic and paralytic forms. It may occur after recovery from a subclinical infection. Treatment is aimed at controlling symptoms while the infection runs its course. The prognosis depends on the form of the disease (subclinical, nonparalytic, or paralytic) and the site affected. If the spinal cord and brain are not involved, which is the case more than 90% of the time, complete recovery is likely.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Poliomyelitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Poliomyelitis" returned 993 free, full-text research articles on human participants. First 3 results:

Performance of acute flaccid paralysis (AFP) surveillance and incidence of poliomyelitis, 2016.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2016 Sep;91(36-37):427-32.

 

Last Updated: 13 Sep 2016

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Performance of acute flaccid paralysis (AFP) surveillance and incidence of poliomyelitis, 2015.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2016 Apr;91(15):203-7.

 

Last Updated: 15 Apr 2016

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Performance of acute flaccid paralysis (AFP) surveillance and incidence of poliomyelitis, 2015.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2015 Dec;90(49):675-9.

 

Last Updated: 4 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Poliomyelitis" returned 33 free, full-text review articles on human participants. First 3 results:

Post-poliomyelitis syndrome as a possible viral disease.
 

Author(s): Andreina Baj, Martina Colombo, Joan L Headley, John R McFarlane, Mary-Ann Liethof, Antonio Toniolo

Journal: Int. J. Infect. Dis.. 2015 Jun;35():107-16.

 

This review summarizes current concepts on post-polio syndrome (PPS), a condition that may arise in polio survivors after partial or complete functional recovery followed by a prolonged interval of stable neurological function. PPS affects 15-20 million people worldwide. Epidemiological ...

Last Updated: 8 Jul 2015

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Vaccine-associated paralytic poliomyelitis: a review of the epidemiology and estimation of the global burden.
 

Author(s): Lauren R Platt, Concepción F Estívariz, Roland W Sutter

Journal: J. Infect. Dis.. 2014 Nov;210 Suppl 1():S380-9.

 

Vaccine-associated paralytic poliomyelitis (VAPP) is a rare adverse event associated with oral poliovirus vaccine (OPV). This review summarizes the epidemiology and provides a global burden estimate.

Last Updated: 15 Oct 2014

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[Eradication of poliomyelitis and emergence of pathogenic vaccine-derived polioviruses: from Madagascar to Cameroon].
 

Author(s): Francis Delpeyroux, Florence Colbère-Garapin, Richter Razafindratsimandresy, Serge Sadeuh-Mba, Marie-Line Joffret, Dominique Rousset, Bruno Blondel

Journal: Med Sci (Paris). 2013 Nov;29(11):1034-41.

 

The oral poliovaccine, a live vaccine made of attenuated poliovirus strains, is the main tool of the vaccination campaigns organised for eradicating poliomyelitis. these campaigns had led to the decline and, thereafter, to the disappearance of wild poliovirus strains of the three ...

Last Updated: 27 Nov 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

To Develop, Implement and Evaluate the Polio Demonstration Project Comprising of a Community Based Intervention Package for Polio Eradication in Pakistan
 

Status: Recruiting

Condition Summary: Polio; Polio Sero Conversion; Polio Sero Prevalence; Immunization Coverage

 

Last Updated: 24 Jul 2013

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Study of Mental Fatigue in Polio Survivors
 

Status: Recruiting

Condition Summary: Post-Poliomyelitis Syndrome

 

Last Updated: 15 Jun 2007

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L-Citrulline in Patients With Post-Polio Syndrome
 

Status: Recruiting

Condition Summary: Post-Polio Syndrome

 

Last Updated: 10 Jun 2016

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