Poliomyelitis

Common Name(s)

Poliomyelitis, Polio

Poliomyelitis is a viral disease that can affect nerves and can lead to partial or full paralysis. It is caused by infection with the poliovirus which can be spread by direct person-to-person contact, by contact with infected mucus or phlegm from the nose or mouth, or by contact with infected feces. Since the development of polio vaccine, the incidence of the disease has been greatly reduced. There are three basic patterns of polio infection: subclinical infections, nonparalytic, and paralytic. Approximately 95% of infections are subclinical infections, which may not have symptoms. Clinical poliomyelitis affects the central nervous system (brain and spinal cord) and is divided into nonparalytic and paralytic forms. It may occur after recovery from a subclinical infection. Treatment is aimed at controlling symptoms while the infection runs its course. The prognosis depends on the form of the disease (subclinical, nonparalytic, or paralytic) and the site affected. If the spinal cord and brain are not involved, which is the case more than 90% of the time, complete recovery is likely.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Poliomyelitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Poliomyelitis" returned 578 free, full-text research articles on human participants. First 3 results:

Progress toward poliomyelitis eradication--Nigeria, January 2013-September 2014.
 

Author(s): Andrew Etsano, Rajni Gunnala, Faisal Shuaib, Eunice Damisa, Pascal Mkanda, Richard Banda, Charles Korir, Ogu Enemaku, Melissa Corkum, Samuel Usman, Lora B Davis, Gatei wa Nganda, Cara C Burns, Frank Mahoney, John F Vertefeuille,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2014 Nov;63(46):1059-63.

 

In 1988, the World Health Assembly resolved to interrupt wild poliovirus (WPV) transmission worldwide. By 2013, only three countries remained that had never interrupted WPV transmission: Afghanistan, Nigeria, and Pakistan. Since 2003, northern Nigeria has been a reservoir for WPV ...

Last Updated: 21 Nov 2014

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Progress towards poliomyelitis eradication: Afghanistan and Pakistan, January 2013–August 2014.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2014 Oct;89(44):493-9.

 

Last Updated: 3 Nov 2014

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Progress toward poliomyelitis eradication--Afghanistan and Pakistan, January 2013-August 2014.
 

Author(s): Noha H Farag, James Alexander, Stephen Hadler, Arshad Quddus, Elias Durry, Mufty Zubair Wadood, Rudolph H Tangermann, Derek Ehrhardt,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2014 Oct;63(43):973-7.

 

In 2012, the World Health Assembly declared the completion of polio eradication a programmatic emergency for global public health and called for a comprehensive polio endgame strategy. Afghanistan and Pakistan are two of the three remaining countries (the other is Nigeria) where circulation ...

Last Updated: 31 Oct 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Poliomyelitis" returned 31 free, full-text review articles on human participants. First 3 results:

[Eradication of poliomyelitis and emergence of pathogenic vaccine-derived polioviruses: from Madagascar to Cameroon].
 

Author(s): Francis Delpeyroux, Florence Colbère-Garapin, Richter Razafindratsimandresy, Serge Sadeuh-Mba, Marie-Line Joffret, Dominique Rousset, Bruno Blondel

Journal: Med Sci (Paris). 2013 Nov;29(11):1034-41.

 

The oral poliovaccine, a live vaccine made of attenuated poliovirus strains, is the main tool of the vaccination campaigns organised for eradicating poliomyelitis. these campaigns had led to the decline and, thereafter, to the disappearance of wild poliovirus strains of the three ...

Last Updated: 27 Nov 2013

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The final stages of the global eradication of poliomyelitis.
 

Author(s): Nicholas C Grassly

Journal:

 

The global incidence of poliomyelitis has dropped by more than 99 per cent since the governments of the world committed to eradication in 1988. One of the three serotypes of wild poliovirus has been eradicated and the remaining two serotypes are limited to just a small number of endemic ...

Last Updated: 26 Jun 2013

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Eradicating poliomyelitis: India's journey from hyperendemic to polio-free status.
 

Author(s): T Jacob John, Vipin M Vashishtha

Journal: Indian J. Med. Res.. 2013 May;137(5):881-94.

 

India's success in eliminating wild polioviruses (WPVs) has been acclaimed globally. Since the last case on January 13, 2011 success has been sustained for two years. By early 2014 India could be certified free of WPV transmission, if no indigenous transmission occurs, the chances ...

Last Updated: 13 Jun 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 17 Jan 2012

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To Develop, Implement and Evaluate the Polio Demonstration Project Comprising of a Community Based Intervention Package for Polio Eradication in Pakistan
 

Status: Recruiting

Condition Summary: Polio; Polio Sero Conversion; Polio Sero Prevalence; Immunization Coverage

 

Last Updated: 24 Jul 2013

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Immunogenicity and Safety of Liquid Bivalent Oral Poliomyelitis Vaccine
 

Status: Not yet recruiting

Condition Summary: Poliomyelitis

 

Last Updated: 4 May 2015

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