Poliomyelitis

Common Name(s)

Poliomyelitis

Poliomyelitis is a viral disease that can affect nerves and can lead to partial or full paralysis. It is caused by infection with the poliovirus which can be spread by direct person-to-person contact, by contact with infected mucus or phlegm from the nose or mouth, or by contact with infected feces. Since the development of polio vaccine, the incidence of the disease has been greatly reduced. There are three basic patterns of polio infection: subclinical infections, nonparalytic, and paralytic. Approximately 95% of infections are subclinical infections, which may not have symptoms. Clinical poliomyelitis affects the central nervous system (brain and spinal cord) and is divided into nonparalytic and paralytic forms. It may occur after recovery from a subclinical infection. Treatment is aimed at controlling symptoms while the infection runs its course. The prognosis depends on the form of the disease (subclinical, nonparalytic, or paralytic) and the site affected. If the spinal cord and brain are not involved, which is the case more than 90% of the time, complete recovery is likely.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Poliomyelitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Poliomyelitis" returned 570 free, full-text research articles on human participants. First 3 results:

Performance of acute flaccid paralysis (AFP) surveillance and incidence of poliomyelitis,2014.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2014 Sep;89(37):405-8.

 

Last Updated: 12 Sep 2014

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Vaccine-associated paralytic poliomyelitis and BCG-osis in an immigrant child with severe combined immunodeficiency syndrome - Texas, 2013.
 

Author(s): Robert Trimble, Jane Atkins, Troy C Quigg, Cara C Burns, Gregory S Wallace, Mary Thomas, Anil T Mangla, Anthony J Infante,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2014 Aug;63(33):721-4.

 

Poliovirus transmission has been eliminated in most of the world through the use of inactivated poliovirus vaccine (IPV) and live, attenuated oral poliovirus vaccine (OPV). In the United States, use of OPV was discontinued by the year 2000 because of the potential for vaccine-associated ...

Last Updated: 22 Aug 2014

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Performance of acute flaccid paralysis (AFP) surveillance and incidence of poliomyelitis, 2014.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2014 Jun;89(26):289-96.

 

Last Updated: 30 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Poliomyelitis" returned 30 free, full-text review articles on human participants. First 3 results:

The final stages of the global eradication of poliomyelitis.
 

Author(s): Nicholas C Grassly

Journal:

 

The global incidence of poliomyelitis has dropped by more than 99 per cent since the governments of the world committed to eradication in 1988. One of the three serotypes of wild poliovirus has been eradicated and the remaining two serotypes are limited to just a small number of endemic ...

Last Updated: 26 Jun 2013

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Eradicating poliomyelitis: India's journey from hyperendemic to polio-free status.
 

Author(s): T Jacob John, Vipin M Vashishtha

Journal: Indian J. Med. Res.. 2013 May;137(5):881-94.

 

India's success in eliminating wild polioviruses (WPVs) has been acclaimed globally. Since the last case on January 13, 2011 success has been sustained for two years. By early 2014 India could be certified free of WPV transmission, if no indigenous transmission occurs, the chances ...

Last Updated: 13 Jun 2013

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Certification of poliomyelitis eradication in Singapore and the challenges ahead.
 

Author(s): Hwee Ching Lee, Joanne Tay, Cynthia Y H Kwok, Moi Kim Wee, Li Wei Ang, Yuske Kita, Jeffery L Cutter, Kwai Peng Chan, Suok Kai Chew, Kee Tai Goh

Journal: Ann. Acad. Med. Singap.. 2012 Nov;41(11):518-28.

 

This study reviewed the epidemiological trends of poliomyelitis from 1946 to 2010, and the impact of the national immunisation programme in raising the population herd immunity against poliovirus. We also traced the efforts Singapore has made to achieve certification of poliomyelitis ...

Last Updated: 13 Dec 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

To Develop, Implement and Evaluate the Polio Demonstration Project Comprising of a Community Based Intervention Package for Polio Eradication in Pakistan
 

Status: Recruiting

Condition Summary: Polio; Polio Sero Conversion; Polio Sero Prevalence; Immunization Coverage

 

Last Updated: 24 Jul 2013

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Last Updated: 17 Jan 2012

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Polio End-game Strategies - Poliovirus Type 2 Challenge Study
 

Status: Not yet recruiting

Condition Summary: Poliomyelitis

 

Last Updated: 14 Jul 2014

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