Poliomyelitis

Common Name(s)

Poliomyelitis, Polio

Poliomyelitis is a viral disease that can affect nerves and can lead to partial or full paralysis. It is caused by infection with the poliovirus which can be spread by direct person-to-person contact, by contact with infected mucus or phlegm from the nose or mouth, or by contact with infected feces. Since the development of polio vaccine, the incidence of the disease has been greatly reduced. There are three basic patterns of polio infection: subclinical infections, nonparalytic, and paralytic. Approximately 95% of infections are subclinical infections, which may not have symptoms. Clinical poliomyelitis affects the central nervous system (brain and spinal cord) and is divided into nonparalytic and paralytic forms. It may occur after recovery from a subclinical infection. Treatment is aimed at controlling symptoms while the infection runs its course. The prognosis depends on the form of the disease (subclinical, nonparalytic, or paralytic) and the site affected. If the spinal cord and brain are not involved, which is the case more than 90% of the time, complete recovery is likely.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Poliomyelitis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Poliomyelitis" returned 949 free, full-text research articles on human participants. First 3 results:

Intrathecal Analgesic Drug Delivery is Effective for Analgesia in a Patient with Post-Poliomyelitis Syndrome: A Case Report.
 

Author(s): Cornelis W J van Tilburg

Journal:

 

BACKGROUND Post-poliomyelitis syndrome (PPS) is a progressive neuromuscular syndrome, with chronic pain being one of the most prevalent symptoms. We present a case report on intrathecal analgesic drug delivery to diminish chro-nic, refractory pain in a patient with PPS. CASE REPORT ...

Last Updated: 16 Dec 2016

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Progress Toward Poliomyelitis Eradication - Pakistan, January 2015-September 2016.
 

Author(s): Christopher H Hsu, Abdirahman Mahamud, Rana Muhammad Safdar, Jamal Ahmed, Jaume Jorba, Salmaan Sharif, Noha Farag, Maureen Martinez, Rudolph H Tangermann, Derek Ehrhardt

Journal:

 

Pakistan, Afghanistan, and Nigeria remain the only countries where endemic wild poliovirus type 1 (WPV1) transmission continues. This report describes the activities, challenges, and progress toward polio eradication in Pakistan during January 2015-September 2016 and updates previous ...

Last Updated: 23 Nov 2016

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Fixator-assisted tibial lengthening over a plate in a patient with sequelae of poliomyelitis.
 

Author(s): Haci Bayram Tosun, Sancar Serbest, Abuzer Uludag, Seyitali Gumustas, Suat Celik

Journal: Medicine (Baltimore). 2016 Nov;95(44):e5252.

 

There are many techniques for limb lengthening. Lengthening over a plate is an alternative choice of fixation in children or when nailing is difficult. We present a new technique for tibial lengthening with using a monolateral external fixator over a lengthening plate.Lengthening ...

Last Updated: 18 Nov 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Poliomyelitis" returned 25 free, full-text review articles on human participants. First 3 results:

Eradication and Current Status of Poliomyelitis in Pakistan: Ground Realities.
 

Author(s): Shazia Ghafoor, Nadeem Sheikh

Journal: J Immunol Res. 2016 ;2016():6837824.

 

Pakistan is among the last three countries along with Afghanistan and Nigeria, where polio virus is still endemic. More or less, with some fluctuations, numbers of reported cases in the past few years have shown a rising trend. Year 2014 pushed the country into the deep sea of difficulties, ...

Last Updated: 12 Aug 2016

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Post-poliomyelitis syndrome as a possible viral disease.
 

Author(s): Andreina Baj, Martina Colombo, Joan L Headley, John R McFarlane, Mary-Ann Liethof, Antonio Toniolo

Journal: Int. J. Infect. Dis.. 2015 Jun;35():107-16.

 

This review summarizes current concepts on post-polio syndrome (PPS), a condition that may arise in polio survivors after partial or complete functional recovery followed by a prolonged interval of stable neurological function. PPS affects 15-20 million people worldwide. Epidemiological ...

Last Updated: 8 Jul 2015

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[Eradication of poliomyelitis and emergence of pathogenic vaccine-derived polioviruses: from Madagascar to Cameroon].
 

Author(s): Francis Delpeyroux, Florence Colbère-Garapin, Richter Razafindratsimandresy, Serge Sadeuh-Mba, Marie-Line Joffret, Dominique Rousset, Bruno Blondel

Journal: Med Sci (Paris). 2013 Nov;29(11):1034-41.

 

The oral poliovaccine, a live vaccine made of attenuated poliovirus strains, is the main tool of the vaccination campaigns organised for eradicating poliomyelitis. these campaigns had led to the decline and, thereafter, to the disappearance of wild poliovirus strains of the three ...

Last Updated: 27 Nov 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study to Evaluate Immunogenicity of Various Schedules of Inactivated Polio Vaccine
 

Status: Not yet recruiting

Condition Summary: Poliomyelitis

 

Last Updated: 13 Jan 2017

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Last Updated: 23 Jan 2017

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Last Updated: 13 Feb 2017

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